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TOBRADEX ST (TOBRAMYCIN/DEXAMETHASONE)
- Ocular inflammation
- Superficial ocular infection
0.3 %-0.05 % eye drops,suspension
- Instill 1 drop into affected eye(s) by ophthalmic route every 6 hours
Ocular inflammation
- Instill 1 drop into left eye by ophthalmic route every 4 hours
- Instill 1 drop into left eye by ophthalmic route every 6 hours
- Instill 1 drop into right eye by ophthalmic route every 4 hours
- Instill 1 drop into right eye by ophthalmic route every 6 hours
- Instill 1 drop into both eyes by ophthalmic route every 4 hours
- Instill 1 drop into both eyes by ophthalmic route every 6 hours
- Instill 1 drop into right eye by ophthalmic route every 4-6 hours
- Instill 1 drop into left eye by ophthalmic route every 4-6 hours
- Instill 1 drop into both eyes by ophthalmic route every 4-6 hours
- Instill 1 drop into affected eye(s) by ophthalmic route every 4-6 hours
- Instill 1 drop into affected eye(s) by ophthalmic route every 4 hours
- Instill 1 drop into affected eye(s) by ophthalmic route every 6 hours
- None
Contraindicated
- None
Severe
Moderate
- None
- Amebic infection of the eye
- Herpes simplex dendritic keratitis
- Tuberculosis of the eye
- Vaccinia virus keratitis
Contraindicated
- Fungal infection of eye
- Herpes zoster ophthalmicus
- Ocular hypertension
Severe
Moderate
- Diabetes mellitus
- Krukenberg spindle
- No disease contraindications
- Open angle glaucoma
- Severe myopia
TOBRADEX ST (TOBRAMYCIN/DEXAMETHASONE)
- Ocular inflammation
- Superficial ocular infection
- None
- Blurred vision
More Frequent
Severe
Less Severe
- Ocular inflammation
- Ocular itching
- Ocular redness
- Blurred vision
- Headache disorder
- Iritis
- Ocular irritation
- Ocular pain
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Cataracts
- Central serous chorioretinopathy
- Corneal degeneration
- Corneal edema
- Corneal erosion
- Corneal ulcer
- Fungal infection of eye
- Glaucoma
- Globe perforation
- Keratitis
- Ocular hypertension
- Punctate keratitis
- Reduced visual acuity
- Uveitis
- Visual changes
- Visual field defect
Less Severe
- Accommodation disorder
- Allergic dermatitis
- Blepharoptosis
- Chemosis
- Conjunctival hyperemia
- Conjunctivitis
- Dizziness
- Dysgeusia
- Eye tearing
- Eyelid edema
- Foreign body sensation of eye
- Impaired wound healing
- Mydriasis
- Ocular infection
- Ocular irritation
- Ocular itching
- Ocular redness
- Photophobia
- Urticaria
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Tobramycin_Dexamethasone (Ophth)
Safety and efficacy not established age < 2 years.
- 1 Day – 2 Years
- Safety and efficacy not established age < 2 years.
Dexamethasone(ophthalmic)
- Severity Level:
2
- Additional Notes: Insuff human data; animal data sug dev tox
Tobramycin Sulfate (ophthalmic)
- Severity Level:
B
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Dexamethasone
Other corticosteroids excreted in trace amounts, potential for adv effects
Poor oral absorption; unlikely clinically significant levels in infant
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Other corticosteroids excreted in trace amounts, potential for adv effects |
Tobramycin
Other corticosteroids excreted in trace amounts, potential for adv effects
Poor oral absorption; unlikely clinically significant levels in infant
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Poor oral absorption; unlikely clinically significant levels in infant |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Dexamethasone(ophth)
Increased risk of diabetes, cataracts, or glaucoma. Frequent ophthalmic exams recommended.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | N | N | N | Y |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Ocular inflammation | |
| H57.8 | Other specified disorders of eye and adnexa |
| Superficial ocular infection | |
| H10.0 | Mucopurulent conjunctivitis |
| H10.01 | Acute follicular conjunctivitis |
| H10.011 | Acute follicular conjunctivitis, right eye |
| H10.012 | Acute follicular conjunctivitis, left eye |
| H10.013 | Acute follicular conjunctivitis, bilateral |
| H10.019 | Acute follicular conjunctivitis, unspecified eye |
| H10.02 | Other mucopurulent conjunctivitis |
| H10.021 | Other mucopurulent conjunctivitis, right eye |
| H10.022 | Other mucopurulent conjunctivitis, left eye |
| H10.023 | Other mucopurulent conjunctivitis, bilateral |
| H10.029 | Other mucopurulent conjunctivitis, unspecified eye |
| 0-9 | A-Z |
|---|---|
| H10.0 | Mucopurulent conjunctivitis |
| H10.01 | Acute follicular conjunctivitis |
| H10.011 | Acute follicular conjunctivitis, right eye |
| H10.012 | Acute follicular conjunctivitis, left eye |
| H10.013 | Acute follicular conjunctivitis, bilateral |
| H10.019 | Acute follicular conjunctivitis, unspecified eye |
| H10.02 | Other mucopurulent conjunctivitis |
| H10.021 | Other mucopurulent conjunctivitis, right eye |
| H10.022 | Other mucopurulent conjunctivitis, left eye |
| H10.023 | Other mucopurulent conjunctivitis, bilateral |
| H10.029 | Other mucopurulent conjunctivitis, unspecified eye |
| H57.8 | Other specified disorders of eye and adnexa |
Formulary Reference Tool