Raajit Rampal, MD, PhD
MPN Expert

Myelofibrosis >
POLYCYTHEMIA VERA
Managing for the risk of thrombosis is a key treatment goal for patients with PV. When it comes to managing for the risk of thrombosis, which counts are you most concerned about?

Hct only

Hct and WBC

Hct and PLT

Hct, PLT, and WBC

Hct=hematocrit; PLT=platelet; WBC=white blood cell.

POLYCYTHEMIA VERA
When managing for the risk of thrombosis, what is your target Hct level for your patients with PV?

<45%

48% to 50%

45% to 47%

>50%

POLYCYTHEMIA VERA
Your PV patient is on their maximum tolerated dose of HU.
At this point, what is the maximum Hct level you would allow before changing your management approach?

45% to <48%

Slightly below 45%

48% to <50%

Unsure

≥50%

HU=hydroxyurea.

POLYCYTHEMIA VERA
When it comes to managing for the risk of thrombosis, what is the maximum WBC count you would allow for your patients with PV?

I try to keep them ≤11 × 109/L

>15 to 20 × 109/L

11 to 15 × 109/L

I do not manage WBC counts for the risk of thrombosis

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Raajit Rampal, MD, PhD
MPN Expert

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