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LEVALBUTEROL TARTRATE HFA (LEVALBUTEROL TARTRATE)
- Bronchospastic pulmonary disease
- Acute asthma attack
- Bronchospasm prevention
45 mcg/actuation aerosol inhaler
- Inhale 2 puffs (90 mcg) by inhalation route every 6 hours
levalbuterol HFA 45 mcg/actuation aerosol inhaler
- Inhale 2 puffs (90 mcg) by inhalation route every 6 hours
Acute asthma attack
- Inhale 1 puff (45 mcg) by inhalation route every 4 hours
- Inhale 2 puffs (90 mcg) by inhalation route every 6 hours
- Inhale 2 puffs (90 mcg) by inhalation route every 4-6 hours
- Inhale 2 puffs (90 mcg) by inhalation route every 4 hours
Bronchospasm prevention
- Inhale 1 puff (45 mcg) by inhalation route every 4 hours
- Inhale 2 puffs (90 mcg) by inhalation route every 6 hours
- Inhale 2 puffs (90 mcg) by inhalation route every 4-6 hours
- Inhale 2 puffs (90 mcg) by inhalation route every 4 hours
Bronchospastic pulmonary disease
- Inhale 1 puff (45 mcg) by inhalation route every 4 hours
- Inhale 2 puffs (90 mcg) by inhalation route every 6 hours
- Inhale 2 puffs (90 mcg) by inhalation route every 4-6 hours
- Inhale 2 puffs (90 mcg) by inhalation route every 4 hours
- None
Contraindicated
- bromocriptine
- cabergoline
- Cafergot
- Compound 347
- Cycloset
- D.h.e.45
- dihydroergotamine
- enflurane
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- Forane
- isoflurane
- methylergonovine
- Migergot
- Migranal
- Parlodel
- sevoflurane
- Sojourn
- Terrell
- Ultane
Severe
Moderate
- None
- None
Contraindicated
- Congenital long QT syndrome
- Hypokalemia
- Prolonged QT interval
Severe
Moderate
- Cardiac arrhythmia
- Chronic myocardial ischemia
- Diabetes mellitus
- Hypertension
- Hyperthyroidism
- Ketoacidosis
- Kidney disease with reduction in GFR
- Metabolic acidosis
- Seizure disorder
LEVALBUTEROL TARTRATE HFA (LEVALBUTEROL TARTRATE)
- Bronchospastic pulmonary disease
- Acute asthma attack
- Bronchospasm prevention
- Bronchitis
- Accidental injury
More Frequent
Severe
Less Severe
- Asthma exacerbation
- Dizziness
- Pain
- Pharyngitis
- Rhinitis
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Angioedema
- Cardiac arrhythmia
- Chest pain
- Conjunctivitis
- Dyspnea
- Epistaxis
- Hematuria
- Hypersensitivity drug reaction
- Hypertension
- Hypokalemia
- Metabolic acidosis
- Paradoxical bronchospasm
- Tachycardia
- Urticaria
Less Severe
- Acne vulgaris
- Constipation
- Cough
- Dysmenorrhea
- Earache
- Flu-like symptoms
- Gastroenteritis
- Gastroesophageal reflux disease
- Headache disorder
- Herpes simplex infection
- Insomnia
- Myalgias
- Nausea
- Nervousness
- Skin rash
- Tremor
- Vertigo
- Viral infection
- Voice change
- Vulvovaginal candidiasis
- Xerostomia
Contraindicated
None
Severe Precaution
Levalbuterol (HFA)
Risk of asthma related adverse events (e.g., hypoxia, status asthmaticus) age < 4 years. No demonstrated efficacy in clinical trials.
- 1 Day – 4 Years
- Risk of asthma related adverse events (e.g., hypoxia, status asthmaticus) age < 4 years. No demonstrated efficacy in clinical trials.
Management or Monitoring Precaution
None
Levalbuterol
- Severity Level:
2
- Additional Notes: Insufficient human data
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Levalbuterol
Plasma levels very low in humans; mfr recommends caution
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Plasma levels very low in humans; mfr recommends caution |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Levalbuterol
Cardiovascular-Use caution in severe cardiovascular diseases, particularly coronary insufficiency, since beta-agonists increase heart rate and blood pressure. Endocrine-Use caution in poorly controlled hyperthyroidism or diabetes.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | N | N | Y |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Acute asthma attack | |
| J45.21 | Mild intermittent asthma with (acute) exacerbation |
| J45.22 | Mild intermittent asthma with status asthmaticus |
| J45.31 | Mild persistent asthma with (acute) exacerbation |
| J45.32 | Mild persistent asthma with status asthmaticus |
| J45.41 | Moderate persistent asthma with (acute) exacerbation |
| J45.42 | Moderate persistent asthma with status asthmaticus |
| J45.51 | Severe persistent asthma with (acute) exacerbation |
| J45.52 | Severe persistent asthma with status asthmaticus |
| J45.901 | Unspecified asthma with (acute) exacerbation |
| J45.902 | Unspecified asthma with status asthmaticus |
| J98.01 | Acute bronchospasm |
| Bronchospasm prevention | |
| J44.9 | Chronic obstructive pulmonary disease, unspecified |
| J45.20 | Mild intermittent asthma, uncomplicated |
| J45.30 | Mild persistent asthma, uncomplicated |
| J45.40 | Moderate persistent asthma, uncomplicated |
| J45.50 | Severe persistent asthma, uncomplicated |
| J45.909 | Unspecified asthma, uncomplicated |
| J45.990 | Exercise induced bronchospasm |
| J45.998 | Other asthma |
| Bronchospastic pulmonary disease | |
| J44.1 | Chronic obstructive pulmonary disease with (acute) exacerbation |
| J44.9 | Chronic obstructive pulmonary disease, unspecified |
| J45 | Asthma |
| J45.2 | Mild intermittent asthma |
| J45.20 | Mild intermittent asthma, uncomplicated |
| J45.21 | Mild intermittent asthma with (acute) exacerbation |
| J45.22 | Mild intermittent asthma with status asthmaticus |
| J45.3 | Mild persistent asthma |
| J45.30 | Mild persistent asthma, uncomplicated |
| J45.31 | Mild persistent asthma with (acute) exacerbation |
| J45.32 | Mild persistent asthma with status asthmaticus |
| J45.4 | Moderate persistent asthma |
| J45.40 | Moderate persistent asthma, uncomplicated |
| J45.41 | Moderate persistent asthma with (acute) exacerbation |
| J45.42 | Moderate persistent asthma with status asthmaticus |
| J45.5 | Severe persistent asthma |
| J45.50 | Severe persistent asthma, uncomplicated |
| J45.51 | Severe persistent asthma with (acute) exacerbation |
| J45.52 | Severe persistent asthma with status asthmaticus |
| J45.9 | Other and unspecified asthma |
| J45.90 | Unspecified asthma |
| J45.901 | Unspecified asthma with (acute) exacerbation |
| J45.902 | Unspecified asthma with status asthmaticus |
| J45.909 | Unspecified asthma, uncomplicated |
| J45.99 | Other asthma |
| J45.990 | Exercise induced bronchospasm |
| J45.998 | Other asthma |
| 0-9 | A-Z |
|---|---|
| J44.1 | Chronic obstructive pulmonary disease with (acute) exacerbation |
| J44.9 | Chronic obstructive pulmonary disease, unspecified |
| J44.9 | Chronic obstructive pulmonary disease, unspecified |
| J45 | Asthma |
| J45.2 | Mild intermittent asthma |
| J45.20 | Mild intermittent asthma, uncomplicated |
| J45.20 | Mild intermittent asthma, uncomplicated |
| J45.21 | Mild intermittent asthma with (acute) exacerbation |
| J45.21 | Mild intermittent asthma with (acute) exacerbation |
| J45.22 | Mild intermittent asthma with status asthmaticus |
| J45.22 | Mild intermittent asthma with status asthmaticus |
| J45.3 | Mild persistent asthma |
| J45.30 | Mild persistent asthma, uncomplicated |
| J45.30 | Mild persistent asthma, uncomplicated |
| J45.31 | Mild persistent asthma with (acute) exacerbation |
| J45.31 | Mild persistent asthma with (acute) exacerbation |
| J45.32 | Mild persistent asthma with status asthmaticus |
| J45.32 | Mild persistent asthma with status asthmaticus |
| J45.4 | Moderate persistent asthma |
| J45.40 | Moderate persistent asthma, uncomplicated |
| J45.40 | Moderate persistent asthma, uncomplicated |
| J45.41 | Moderate persistent asthma with (acute) exacerbation |
| J45.41 | Moderate persistent asthma with (acute) exacerbation |
| J45.42 | Moderate persistent asthma with status asthmaticus |
| J45.42 | Moderate persistent asthma with status asthmaticus |
| J45.5 | Severe persistent asthma |
| J45.50 | Severe persistent asthma, uncomplicated |
| J45.50 | Severe persistent asthma, uncomplicated |
| J45.51 | Severe persistent asthma with (acute) exacerbation |
| J45.51 | Severe persistent asthma with (acute) exacerbation |
| J45.52 | Severe persistent asthma with status asthmaticus |
| J45.52 | Severe persistent asthma with status asthmaticus |
| J45.9 | Other and unspecified asthma |
| J45.90 | Unspecified asthma |
| J45.901 | Unspecified asthma with (acute) exacerbation |
| J45.901 | Unspecified asthma with (acute) exacerbation |
| J45.902 | Unspecified asthma with status asthmaticus |
| J45.902 | Unspecified asthma with status asthmaticus |
| J45.909 | Unspecified asthma, uncomplicated |
| J45.909 | Unspecified asthma, uncomplicated |
| J45.99 | Other asthma |
| J45.990 | Exercise induced bronchospasm |
| J45.990 | Exercise induced bronchospasm |
| J45.998 | Other asthma |
| J45.998 | Other asthma |
| J98.01 | Acute bronchospasm |
Formulary Reference Tool