VOWST® (fecal microbiota spores, live-brpk) capsules, sponsored by Nestlé Health Science and Seres Therapeutics, Inc.



  • Patient Savings

    Patient Savings

  • Request A Rep

    Request A Rep

  • Call Us

    Call Us

Resources for Your Practice
4 FILES

Physician Resources
Patient Resources
Savings and Support
2 FILES

Savings and Support
Indications & Usage

VOWST is indicated to prevent the recurrence of Clostridioides difficile infection (CDI) in individuals 18 years of age and older following antibacterial treatment for recurrent CDI (rCDI). 

Limitation of Use: VOWST is not indicated for treatment of CDI. 

 

Click here to see full Prescribing Information and Patient Information.

Dosage & Administration

For oral administration only.  

  • Prior to taking the first dose:

o Complete antibacterial treatment for rCDI 2 to 4 days before initiating treatment with VOWST.  

o Drink 296 mL (10 oz) of magnesium citrate on the day before and at least 8 hours prior to taking the first dose of VOWST. In clinical studies, participants with impaired kidney function received polyethylene glycol electrolyte solution (250 mL GoLYTELY, not approved for this use). 

  • The dosage of VOWST is 4 capsules taken orally once daily for 3 consecutive days.   
  • Take each dose (4 capsules) on an empty stomach prior to the first meal of the day.

Capsule. A single dose is 4 capsules. 

 

Click here to see full Prescribing Information and Patient Information.

Adverse Reactions

Most common adverse reactions (reported in ≥5% of participants) were abdominal distension (31.1%), fatigue (22.2%), constipation (14.4%), chills (11.1%) and diarrhea (10.0%). (6.1)   To report SUSPECTED ADVERSE REACTIONS, contact Aimmune Therapeutics, Inc. at 1-833-246-2566 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.  

 

Click here to see full Prescribing Information and Patient Information.

Drug Interactions

Antibacterials should not be administered concurrently with VOWST. 

 

Click here to see full Prescribing Information and Patient Information.

SERES and the Seres logo, VOWST, VOWST Voyage, and the Vowst logo are trademarks of Seres Therapeutics, Inc.  Unless otherwise indicated, all trademarks are owned by Société des Produits Nestlé S.A., Vevey, Switzerland or used with permission.
GoLYTELY is a registered trademark of Braintree Laboratories, Inc.

© 2024 Nestlé. VOW-PM-USA-0242 01/24

Click here to see full Prescribing Information and Patient Information.


INDICATION

VOWST is indicated to prevent the recurrence of Clostridioides difficile infection (CDI) in individuals
18 years of age and older following antibacterial treatment for recurrent CDI (rCDI).

Limitation of Use: VOWST is not indicated for treatment of CDI.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

Transmissible infectious agents: Because VOWST is manufactured from human fecal matter, it may carry a risk of transmitting infectious agents. Report any infection that is suspected to have been transmitted by VOWST to Aimmune Therapeutics, Inc. at 1-833-246-2566.

Potential presence of food allergens: VOWST may contain food allergens. The potential to cause adverse reactions due to food allergens is unknown.

ADVERSE REACTIONS

The most common adverse reactions (reported in ≥5% of Vowst-treated participants, and at a rate greater than placebo) were abdominal distension (31.1%), fatigue (22.2%), constipation (14.4%), chills (11.1%), and diarrhea (10.0%).

To report SUSPECTED ADVERSE REACTIONS, contact Aimmune Therapeutics at 1-833-AIM-2KNO
(1-833-246-2566), or the FDA at 1-800-FDA-1088, or visit www.fda.gov/MedWatch.

DRUG INTERACTIONS

Do not administer antibacterials concurrently with VOWST.

Click here to see full Prescribing Information and Patient Information.