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LABETALOL HCL (labetalol HCl)
- Hypertension
100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day
200 mg tablet
- 1 tablet (200 mg) by oral route 2 times per day
300 mg tablet
- 1 tablet (300 mg) by oral route 2 times per day
labetalol 100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day
labetalol 200 mg tablet
- 1 tablet (200 mg) by oral route 2 times per day
labetalol 300 mg tablet
- 1 tablet (300 mg) by oral route 2 times per day
100 mg tablet
- 1 tablet (100 mg) by oral route 2 times per day
200 mg tablet
- 1 tablet (200 mg) by oral route 2 times per day
300 mg tablet
- 1 tablet (300 mg) by oral route 2 times per day
5 mg/mL intravenous solution
- Inject 4 milliliters (20 mg) over 2 minute(s) by intravenous route ; may repeat every 10 min until desired effect or a total of 300 mg
labetalol 5 mg/mL intravenous solution
- Inject 4 milliliters (20 mg) over 2 minute(s) by intravenous route ; may repeat every 10 min until desired effect or a total of 300 mg
Hypertension
- Infuse 2 mg/minute by continuous infusion route
- Infuse 0.5 mg/minute by continuous infusion route
- Infuse 2 mg/minute by continuous infusion route at a rate of 2 ml/min
- Infuse 2 mg/minute by continuous infusion route at a rate of 3 ml/min
- Infuse 1 mg/minute by continuous infusion route
- Inject 2 milliliters (10 mg) over 2 minute(s) by intravenous route ; may repeat every 10 min until desired effect or a total of 300 mg
- Inject 4 milliliters (20 mg) over 2 minute(s) by intravenous route ; may repeat every 10 min until desired effect or a total of 300 mg
- Inject 8 milliliters (40 mg) over 2 minute(s) by intravenous route ; may repeat every 10 min until desired effect or a total of 300 mg
- Inject 16 milliliters (80 mg) over 2 minute(s) by intravenous route ;May repeat every 10 min until desired effect or a total of 300 mg
- 1 tablet (100 mg) by oral route 2 times per day
- 2 tablets (200 mg) by oral route 2 times per day
- 1 tablet (200 mg) by oral route 2 times per day
- 1 tablet (300 mg) by oral route 2 times per day
- 2 tablets (400 mg) by oral route 2 times per day
- 2 tablets (600 mg) by oral route 2 times per day
- 2 tablets (600 mg) by oral route 3 times per day
- None
Contraindicated
- Adrenaclick
- Adrenalin
- Asthmanefrin Refill
- Asthmanefrin Starter Kit
- Auvi-q
- Bronchial Mist
- Bronchial Mist Refill
- bupivacaine-epinephrine
- bupivacaine-epinephrine (PF)
- bupivacaine-epinephrine bitart
- Catapres
- Catapres-tts-1
- Catapres-tts-2
- Catapres-tts-3
- clonidine
- clonidine (PF)
- clonidine-chlorthalidone
- Clorpres
- Compound 347
- Corlopam
- Duraclon (pf)
- enflurane
- epinephrine
- epinephrine (PF)
- epinephrine base (refill)
- epinephrine HCl
- Epipen
- Epipen 2-pak
- Epipen Jr
- Epipen Jr 2-pak
- fenoldopam
- fingolimod
- Forane
- Gilenya
- isoflurane
- Kapvay
- lidocaine-epinephrine
- lidocaine-epinephrine (PF)
- lidocaine-epinephrine bit
- Marcaine-epinephrine
- Marcaine-epinephrine (pf)
- methyldopa
- methyldopa-hydrochlorothiazide
- methyldopate
- racepinephrine
- S2 Racepinephrine
- Sensorcaine-mpf/epinephrine
- Sensorcaine/epinephrine
- sevoflurane
- Sojourn
- Terrell
- Ultane
- Xylocaine-epinephrine
- Xylocaine-mpf/epinephrine
Severe
Moderate
- Adalat Cc
- Afeditab Cr
- Amaryl
- Apidra
- Apidra Solostar
- Calan
- Calan Sr
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- Diabeta
- Dilacor Xr
- Dilt-xr
- diltiazem HCl
- Duetact
- glimepiride
- glipizide
- glipizide-metformin
- Glucotrol
- Glucotrol Xl
- Glucovance
- glyburide
- glyburide micronized
- glyburide-metformin
- Glynase
- Humalog
- Humalog Kwikpen
- Humalog Mix 50-50
- Humalog Mix 50-50 Kwikpen
- Humalog Mix 75-25
- Humalog Mix 75-25 Kwikpen
- Humulin 70/30
- Humulin N
- Humulin N Kwikpen
- Humulin R
- Humulin R U-500 "Concentrated"
- insulin asp prt-insulin aspart
- insulin aspart
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin lispro
- insulin lispro protam-lispro
- insulin NPH and regular human
- insulin regular hum U-500 conc
- insulin regular human
- Lantus
- Lantus Solostar
- Levemir
- Levemir Flexpen
- Matzim La
- nateglinide
- Nifedical Xl
- nifedipine
- Novolin 70/30
- Novolin N
- Novolin R
- Novolog
- Novolog Flexpen
- Novolog Mix 70-30
- Novolog Mix 70-30 Flexpen
- Novolog Penfill
- NPH insulin human recomb
- pioglitazone-glimepiride
- Procardia
- Procardia Xl
- Starlix
- Tarka
- Taztia Xt
- Tiazac
- tolazamide
- tolbutamide
- trandolapril-verapamil
- verapamil
- Verelan
- Verelan Pm
- Acute decompensated heart failure
- Asthma
- Cardiogenic shock
- Complete atrioventricular block
- Incomplete AV heart block
- Severe hypotension
- Sinus bradycardia
Contraindicated
- Hypotension
- Severe hepatic disease
Severe
Moderate
- Depression
- Diabetes mellitus
- Disease of liver
- Intraoperative floppy iris syndrome
- Kidney disease with reduction in GFR
- Pulmonary emphysema
LABETALOL HCL (labetalol HCl)
- Hypertension
- None
- Abnormal sexual function
- Drowsy
- Fatigue
- General weakness
- Insomnia
More Frequent
Severe
Less Severe
- Bronchospastic pulmonary disease
- Chronic heart failure
- Depression
- Dizziness
- Abdominal pain with cramps
- Constipation
- Diarrhea
- Nasal congestion
- Nausea
- Nervousness
- Symptoms of anxiety
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute confusion
- Arthralgias
- Back pain
- Cardiac arrhythmia
- Chest pain
- Drug-induced hepatitis
- Hallucinations
- Leukopenia
- Orthostatic hypotension
- Psoriasiform eruption
- Thrombocytopenic disorder
Less Severe
- Dry eye
- Dysgeusia
- Hypesthesia
- Nightmares
- Ocular irritation
- Pruritus of skin
- Tingling sensation of hands or feet
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Labetalol
Limited safety data available in pediatrics.
- 1 Day – 18 Years
- Limited safety data available in pediatrics.
Labetalol
- Severity Level:
C
- Additional Notes: Reports of intrauterine growth retardation;monitor fetus/infant for b-blockade
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Labetalol
Limited data suggest low level excreted with low risk for adverse effects
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest low level excreted with low risk for adverse effects |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Labetalol Hcl
Cardiovascular-Minimize dose to decrease dizziness and falls. Older adults may require lower maintenance doses.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | N | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- None
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
Formulary Reference Tool