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DOXAZOSIN MESYLATE (doxazosin mesylate)
- Benign prostatic hyperplasia with lower urinary tract sx
- Hypertension
doxazosin 1 mg tablet
- 1 tablet (1 mg) by oral route once daily
doxazosin 2 mg tablet
- 1 tablet (2 mg) by oral route once daily
doxazosin 4 mg tablet
- 1 tablet (4 mg) by oral route once daily
doxazosin 8 mg tablet
- 1 tablet (8 mg) by oral route once daily
1 mg tablet
- 1 tablet (1 mg) by oral route once daily
2 mg tablet
- 1 tablet (2 mg) by oral route once daily
4 mg tablet
- 1 tablet (4 mg) by oral route once daily
8 mg tablet
- 1 tablet (8 mg) by oral route once daily
Benign prostatic hyperplasia with lower urinary tract sx
- 1 tablet (1 mg) by oral route once daily
- 2 tablets (2 mg) by oral route once daily
- 1 tablet (2 mg) by oral route once daily
- 2 tablets (4 mg) by oral route once daily
- 1 tablet (4 mg) by oral route once daily
- 2 tablets (8 mg) by oral route once daily
- 1 tablet (8 mg) by oral route once daily
Hypertension
- 1 tablet (1 mg) by oral route once daily
- 2 tablets (2 mg) by oral route once daily
- 1 tablet (2 mg) by oral route once daily
- 2 tablets (4 mg) by oral route once daily
- 1 tablet (4 mg) by oral route once daily
- 2 tablets (8 mg) by oral route once daily
- 1 tablet (8 mg) by oral route once daily
- 2 tablets (16 mg) by oral route once daily
- boceprevir
- Victrelis
Contraindicated
- None
Severe
Moderate
- acebutolol
- Adcirca
- atenolol
- atenolol-chlorthalidone
- avanafil
- betaxolol
- Betimol
- brimonidine-timolol
- Cialis
- Combigan
- Corgard
- Corzide
- Cosopt
- Cosopt Pf
- dorzolamide-timolol
- dorzolamide-timolol (PF)
- Dutoprol
- Inderal La
- Inderal Xl
- Innopran Xl
- Istalol
- Levitra
- Lopressor
- Lopressor Hct
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- nadolol
- nadolol-bendroflumethiazide
- pindolol
- propranolol
- propranolol-hydrochlorothiazid
- Revatio
- Sectral
- sildenafil
- Stendra
- tadalafil
- Tenoretic 100
- Tenoretic 50
- Tenormin
- timolol
- timolol maleate
- timolol maleate (PF)
- Timoptic
- Timoptic Ocudose (pf)
- Timoptic-xe
- Toprol Xl
- vardenafil
- Viagra
- None
Contraindicated
- Orthostatic hypotension
Severe
Moderate
- Cataract surgery
- Disease of liver
- Hypotension
- Intraoperative floppy iris syndrome
DOXAZOSIN MESYLATE (doxazosin mesylate)
- Benign prostatic hyperplasia with lower urinary tract sx
- Hypertension
- None
- Dizziness
- Fatigue
- General weakness
- Headache disorder
- Hypotension
More Frequent
Severe
Less Severe
- Dyspnea
- Orthostatic hypotension
- Tachycardia
- Acute abdominal pain
- Drowsy
- Dyspepsia
- Edema
- Irritability
- Myalgias
- Nausea
- Palpitations
- Rhinitis
- Upper respiratory infection
- Urinary tract infection
- Vertigo
- Xerostomia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Angioedema
- Bradycardia
- Bronchospastic pulmonary disease
- Cardiac arrhythmia
- Cholestasis
- Cholestatic hepatitis
- Chronic heart failure
- Gastrointestinal obstruction
- Hepatitis
- Intraoperative floppy iris syndrome
- Jaundice
- Leukopenia
- Neutropenic disorder
- Priapism
- Purpura
- Thrombocytopenic disorder
- Urticaria
- Visual changes
Less Severe
- Alopecia
- Angina
- Arthralgias
- Blurred vision
- Chest pain
- Cramps
- Diarrhea
- Dysuria
- Epistaxis
- Erectile dysfunction
- Flushing
- Gynecomastia
- Hematuria
- Hypesthesia
- Increased urinary frequency
- Insomnia
- Libido changes
- Malaise
- Muscle weakness
- Nervousness
- Nocturia
- Paresthesia
- Polyuria
- Pruritus of skin
- Skin rash
- Symptoms of anxiety
- Syncope
- Vomiting
- Weight gain
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Doxazosin
Safety and efficacy not established.
- 1 Day – 18 Years
- Safety and efficacy not established.
Doxazosin
- Severity Level:
2
- Additional Notes: Insuff human data avail; animal data does not suggest developmental toxicity
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Doxazosin
Limited data suggest small amount excreted w/no known adv effects on infant
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest small amount excreted w/no known adv effects on infant |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Doxazosin
Cardiovascular-Orthostatic hypotension more frequent age >70 years and during the first few days of dosing. May predispose to increased falls. Avoid if syncope is due to orthostasis. Consider alternative agent if treating hypertension. Urogenital-May aggravate urinary incontinence in women,
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | Y | N | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- None
| Benign prostatic hyperplasia with lower urinary tract sx | |
| N40.1 | Benign prostatic hyperplasia with lower urinary tract symptoms |
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| N40.1 | Benign prostatic hyperplasia with lower urinary tract symptoms |
Formulary Reference Tool