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Drug overview for GEL-ONE (hyaluronate sod, cross-linked):
Generic name: hyaluronate sod, cross-linked (HYE-a-loo-RON-ate)
Drug class: Visco-Elastics, Intra-articular
Therapeutic class: Locomotor System
No enhanced Introduction information available for this drug.
No enhanced Uses information available for this drug.
Generic name: hyaluronate sod, cross-linked (HYE-a-loo-RON-ate)
Drug class: Visco-Elastics, Intra-articular
Therapeutic class: Locomotor System
No enhanced Introduction information available for this drug.
No enhanced Uses information available for this drug.
DRUG IMAGES
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The following indications for GEL-ONE (hyaluronate sod, cross-linked) have been approved by the FDA:
Indications:
Osteoarthritis of the knee
Professional Synonyms:
Degenerative arthritis of the knee
Degenerative joint disease of the knee
DJD of the knee
Hypertrophic arthritis of the knee
OA of the knee
Osteoarthrosis of the knee
Indications:
Osteoarthritis of the knee
Professional Synonyms:
Degenerative arthritis of the knee
Degenerative joint disease of the knee
DJD of the knee
Hypertrophic arthritis of the knee
OA of the knee
Osteoarthrosis of the knee
The following dosing information is available for GEL-ONE (hyaluronate sod, cross-linked):
No enhanced Dosing information available for this drug.
No enhanced Administration information available for this drug.
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| GEL-ONE 30 MG/3 ML SYRINGE | Maintenance | Adults inject 3 milliliters (30 mg) by intra-articular route to the affected knee(s) once |
No generic dosing information available.
The following drug interaction information is available for GEL-ONE (hyaluronate sod, cross-linked):
There are 0 contraindications.
There are 0 severe interactions.
There are 0 moderate interactions.
The following contraindication information is available for GEL-ONE (hyaluronate sod, cross-linked):
Drug contraindication overview.
No enhanced Contraindications information available for this drug.
No enhanced Contraindications information available for this drug.
There are 0 contraindications.
There are 1 severe contraindications.
Adequate patient monitoring is recommended for safer drug use.
| Severe List |
|---|
| Infection of bone, joint, skin, or soft tissue of knee |
There are 0 moderate contraindications.
The following adverse reaction information is available for GEL-ONE (hyaluronate sod, cross-linked):
Adverse reaction overview.
No enhanced Common Adverse Effects information available for this drug.
No enhanced Common Adverse Effects information available for this drug.
There are 4 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. |
Anaphylaxis Drug fever Skin rash Urticaria |
| Rare/Very Rare |
|---|
| None. |
There are 11 less severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
|
Abdominal pain with cramps Anorexia Diarrhea Ecchymosis Gastrointestinal irritation Headache disorder Injection site sequelae Knee inflammation Nausea Pruritus of skin Vomiting |
None. |
| Rare/Very Rare |
|---|
| None. |
The following precautions are available for GEL-ONE (hyaluronate sod, cross-linked):
No enhanced Pediatric Use information available for this drug.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
No enhanced Pregnancy information available for this drug.
| Drug/Drug Class | Severity | Precaution Description | Pregnancy Category Description |
|---|---|---|---|
| Hyaluronate | 2 | No fda rating; insufficient data available | No fda rating but may have precautions or warnings; may have animal and/or human studies or pre or post marketing information. |
No enhanced Lactation information available for this drug.
Precaution Exists
Precaution exists. (No data or inconclusive human data.) Use of this drug by breast feeding mothers should be evaluated carefully.
Precaution Exists
Precaution exists. (No data or inconclusive human data.) Use of this drug by breast feeding mothers should be evaluated carefully.
| Drug Name | Excretion Potential | Effect on Infant | Notes |
|---|---|---|---|
| Hyaluronate Sodium | Unknown. It is unknown whether the drug is excreted in human breast milk. | It is not known whether this drug has an adverse effect on the nursing infant. (No data or inconclusive human data) | Insufficient human data available |
No enhanced Geriatric Use information available for this drug.
The following prioritized warning is available for GEL-ONE (hyaluronate sod, cross-linked):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for GEL-ONE (hyaluronate sod, cross-linked)'s list of indications:
| Osteoarthritis of the knee | |
| M17 | Osteoarthritis of knee |
| M17.0 | Bilateral primary osteoarthritis of knee |
| M17.1 | Unilateral primary osteoarthritis of knee |
| M17.10 | Unilateral primary osteoarthritis, unspecified knee |
| M17.11 | Unilateral primary osteoarthritis, right knee |
| M17.12 | Unilateral primary osteoarthritis, left knee |
| M17.2 | Bilateral post-traumatic osteoarthritis of knee |
| M17.3 | Unilateral post-traumatic osteoarthritis of knee |
| M17.30 | Unilateral post-traumatic osteoarthritis, unspecified knee |
| M17.31 | Unilateral post-traumatic osteoarthritis, right knee |
| M17.32 | Unilateral post-traumatic osteoarthritis, left knee |
| M17.4 | Other bilateral secondary osteoarthritis of knee |
| M17.5 | Other unilateral secondary osteoarthritis of knee |
| M17.9 | Osteoarthritis of knee, unspecified |
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