EFFEXOR XR (VENLAFAXINE HCL)

Moderate

• abciximab

• Ablavar

• Abstral

• Actiq

• Activase

• Added Strength Headache Relief

• Added Strength Pain Reliever

• Adderall

• Adderall Xr

• Adipex-p

• Adult Low Dose Aspirin

• Advil

• Advil Allergy Sinus

• Advil Allergy-congestion Rlf

• Advil Cold & Sinus

• Advil Congestion Relief

• Advil Liqui-gel

• Advil Migraine

• Advil Pm

• Advil Pm Liqui-gels

• Aggrastat In Sodium Chloride

• Aggrenox

• Aleve

• Aleve Cold & Sinus

• Aleve Sinus & Headache

• Aleve-d Sinus & Cold

• Aleve-d Sinus & Headache

• alfuzosin

• Alka-seltzer

• Alka-seltzer Extra Strength

• Alka-seltzer Original

• Alka-seltzer Plus C/c(pe,dm)

• Alka-seltzer Plus Cold (pe)

• Alka-seltzer Plus Day-night

• Alka-seltzer Plus Night

• Alka-seltzer Pm

• All Day Pain Relief

• All Day Pain Relief Sinus & Co

• All Day Relief

• almotriptan malate

• Alsuma

• alteplase

• Amerge

• Amphetamine Salt Combo

• Anacin

• Anacin Maximum Strength

• Analgesic

• Anaprox

• Anaprox Ds

• Ansaid

• Antacid & Pain Relief

• Anzemet

• Apokyn

• apomorphine

• arsenic trioxide

• Arthri-flex

• Arthrotec 50

• ASA-acetaminophen-caff-buffers

• ASA-acetaminophen-salicyl-caff

• Ascomp With Codeine

• Aspir-81

• Aspir-low

• Aspir-trin

• aspirin

• Aspirin Childrens

• Aspirin Low Dose

• Aspirin Low-strength

• aspirin, buffered

• aspirin-acetaminophen-caffeine

• aspirin-caffeine

• aspirin-calcium carbonate

• aspirin-diphenhydramine

• aspirin-diphenhydramine citrat

• aspirin-sod bicarb-citric acid

• Avelox

• Avelox Abc Pack

• Avelox In Nacl (iso-osmotic)

• Axert

• Back & Body Pain Reliever

• Bayer Advanced

• Bayer Aspirin

• Bayer Aspirin (with Caffeine)

• Bayer Back & Body

• Bayer Chewable Aspirin

• Bayer Childrens Aspirin

• Bayer Plus Extra Strength

• Bayer Pm

• Bc

• Bc Arthritis

• bedaquiline

• Betapace

• Betapace Af

• Brilinta

• Buffered Aspirin

• Bufferin

• Butalbital Compound W/codeine

• Butalbital Compound-codeine

• butalbital-aspirin-caffeine

• Caldolor

• Cambia

• Caprelsa

• carisoprodol-ASA-codeine

• carisoprodol-aspirin

• Cataflam

• Celebrex

• celecoxib

• Celexa

• Child Aspirin

• Child Ibuprofen

• Children's Advil

• Children's Aspirin

• Children's Ibu-drops

• Children's Ibuprofen

• Children's Medi-profen

• Children's Motrin

• Children's Profen Ib

• chlorphen-phenyleph-DM-aspirin

• chlorphen-phenyleph-ibuprofen

• chlorphen-pseudoeph-ibuprofen

• chlorphenir-phenylephrn-aspirn

• cilostazol

• Cipro

• Cipro In D5W

• Cipro Xr

• ciprofloxacin

• ciprofloxacin (mixture)

• ciprofloxacin in D5W

• citalopram

• clopidogrel

• clozapine

• Clozaril

• codeine-butalbital-ASA-caff

• Cold & Sinus Pain Relief

• Cold Relief

• Cold Relief Plus

• Cold-sinus Relief

• Complera

• Conzip

• crizotinib

• dasatinib

• Daypro

• Desoxyn

• Dexedrine Spansule

• dextroamphetamine

• dextroamphetamine-amphetamine

• diclofenac epolamine

• diclofenac potassium

• diclofenac sodium

• diclofenac submicronized

• diclofenac-misoprostol

• dihydrocodeine-aspirin-caff

• dipyridamole-aspirin

• Diskets

• dofetilide

• dolasetron

• Dolophine

• doxylamine-phenylep-DM-aspirin

• Duexis

• Duragesic

• E.c. Prin

• Ec-naprosyn

• Ecotrin

• Ecotrin Low Strength

• Edurant

• Efferves Pain Relief Antacid

• Effervescent Antacid

• Effervescent Pain Relief

• Effervescent Pain Reliever

• eletriptan HBr

• emtricitab-rilpivirine-tenofov

• Endodan

• Enteric Coated Aspirin

• eptifibatide

• eribulin

• escitalopram oxalate

• etodolac

• Excedrin Extra Strength

• Excedrin Migraine

• Extra Strength Bayer

• ezogabine

• Fazaclo

• Feldene

• fenoprofen

• fentanyl

• fentanyl citrate

• fentanyl citrate (PF)

• Fentora

• Fiorinal

• Fiorinal-codeine #3

• Flanax

• Flector

• flurbiprofen

• Frova

• frovatriptan

• gadofosveset trisodium

• gluc-msm-coll2-hyal-antiarthr3

• glucos-msm-C-Mn-ginger-willow

• glucos-msm-C-Mn-herb#21

• glucos-msm-collagen-C-Mn-hrb21

• Glucosamine-msm Complex

• Goody's Extra Strength

• Goody's Migraine Relief

• Halaven

• Haldol

• Haldol Decanoate

• haloperidol

• haloperidol decanoate

• haloperidol lactate

• Headache Formula

• Headache Formula Added Str

• Headache Relief

• heparin (porcine)

• heparin (porcine) in D5W

• heparin(porcine) in 0.45% NaCl

• heparin, porcine (PF)

• hydrocodone-ibuprofen

• I-prin

• Ibu-drops

• Ibudone

• ibuprofen

• Ibuprofen Cold

• Ibuprofen Cold-sinus(with Pse)

• Ibuprofen Ib

• Ibuprofen Jr Strength

• ibuprofen lysine (PF)

• Ibuprofen Pm

• ibuprofen-diphenhydramine

• ibuprofen-diphenhydramine HCl

• ibuprofen-famotidine

• ibuprofen-oxycodone

• ibuprofen-phenylephrine HCl

• Imitrex

• Imitrex Statdose Kit Refill

• Imitrex Statdose Pen

• Indocin

• indomethacin

• indomethacin sodium

• Infant's Ibuprofen

• Infant's Medi-profen

• Infant's Motrin

• Infants Ibu-drops

• Infants Profenib

• Integrilin

• Invega

• Invega Sustenna

• Invirase

• Istodax

• Kaletra

• ketoprofen

• ketorolac

• Lamisil

• lapatinib

• Lazanda

• Levacet

• Levaquin

• Levaquin In 5 % Dextrose

• levmetamfetamine

• levofloxacin

• levofloxacin in D5W

• Lexapro

• lisdexamfetamine

• Lite Coat Aspirin

• lithium carbonate

• lithium citrate

• Lithobid

• Lo-dose Aspirin

• lopinavir-ritonavir

• Maxalt

• Maxalt-mlt

• Medi-profen

• Medi-seltzer

• Mediproxen

• mefenamic acid

• meloxicam

• methadone

• Methadone Intensol

• Methadose

• methamphetamine

• Midol (naproxen)

• Migraine Formula

• Migraine Pain Reliever

• Migraine Relief

• Mobic

• Motrin Ib

• Motrin Pm

• moxifloxacin

• moxifloxacin in NaCl (iso-osm)

• Msm Glucosamine Complex

• nabumetone

• Nalfon

• Naprelan Cr

• Naprosyn

• naproxen

• naproxen sodium

• naproxen-esomeprazole

• naproxen-pseudoephedrine

• naratriptan

• Neoprofen (ibuprofen Lysn)(pf)

• Nexavar

• nilotinib

• norfloxacin

• Noroxin

• Noxafil

• Nucynta

• Nucynta Er

• ondansetron

• ondansetron HCl

• ondansetron HCl (PF)

• Orphenadrine Compound Forte

• Orphenadrine Compound-ds

• orphenadrine-ASA-caffeine

• oxaprozin

• oxycodone-aspirin

• Pain Relief

• Pain Relief Extra Strength

• Pain Reliever

• Pain Reliever Extra Strength

• Pain Reliever Plus

• Pain-off

• paliperidone

• paliperidone palmitate

• Pamprin Max

• pasireotide

• pazopanib

• PE-DM-ASA/doxyla-PE-DM-ASA

• Pennsaid

• Percodan

• phentermine

• phentermine-topiramate

• piroxicam

• Plavix

• Pletal

• Ponstel

• posaconazole

• Potiga

• Procentra

• propafenone

• Provil

• pseudoephedrine-ibuprofen

• Qsymia

• Qualaquin

• quetiapine

• quinine sulfate

• Relpax

• Reopro

• Reprexain

• Retavase

• reteplase

• rilpivirine

• rizatriptan

• romidepsin

• Rythmol

• saquinavir mesylate

• Seroquel

• Seroquel Xr

• Signifor

• Sinus & Cold-d

• Sirturo

• Solaraze

• sorafenib

• Sorine

• sotalol

• Sotalol Af

• Sprix

• Sprycel

• St Joseph Aspirin

• St. Joseph Aspirin

• Sublimaze (pf)

• Subsys

• sulindac

• sumatriptan

• sumatriptan succinate

• Sumavel Dosepro

• Super Pain Relief

• Suprenza

• Synalgos-dc

• Synapryn

• tapentadol

• Tasigna

• telavancin

• tenecteplase

• terbinafine

• tetrabenazine

• ticagrelor

• ticlopidine

• Tikosyn

• tirofiban-0.9% sodium chloride

• Tnkase

• tolmetin

• tramadol

• tramadol-acetaminophen

• tramadol-glucosamine

• Tri-buffered Aspirin

• Trisenox

• Tykerb

• Ultracet

• Ultram

• Ultram Er

• Uroxatral

• vandetanib

• Vanquish

• Vapor Inhaler

• vemurafenib

• Versacloz

• Vibativ

• Vicoprofen

• Vimovo

• Voltaren-xr

• Votrient

• Vyvanse

• Wal-profen

• Wal-profen Cold-sinus

• Wal-proxen

• Women's Aspirin With Calcium

• Xalkori

• Xenazine

• Zelboraf

• Zenzedi

• Zipsor

• Zofran

• Zofran Odt

• zolmitriptan

• Zomig

• Zomig Zmt

• Zorvolex

• Zuplenz

Moderate

• Hypercholesterolemia

• Hypomania

• Hyponatremia

• Increased risk of bleeding

• Increased risk of bleeding due to coagulation disorder

• Manic disorder

• SIADH syndrome

• Weight loss

Venlafaxine

• Severity Level:

  C

• Additional Notes: Non-teratogenic complications (resp, gi,cns) with exposure during 3rd trimester

Contraindicated

None

General	Excretion Potential	Effect on Infant	Notes
			None

Precaution Exists

Venlafaxine

No known infant adv effects with short term tx, long term cns effects unknown

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Not known; no or inclusive data	No known infant adv effects with short term tx, long term cns effects unknown

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Venlafaxine

Hepatic-May need to adjust dose, especially in combination with renal impairment. Renal-Decrease initial dose by 25% in mild to moderate renal impairment. Endocrine-Increased risk of SIADH and hyponatremia resulting in an increased risk of falls. Cardiovascular-Elderly at increased risk for orthostatic hypotension.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	Y	Y	N	N	Y

BEERS: Y     HEDIS: Y     STOPP: Y

No Known Risk

None

0-9	A-Z
F32	Major depressive disorder, single episode
F32.0	Major depressive disorder, single episode, mild
F32.1	Major depressive disorder, single episode, moderate
F32.2	Major depressive disorder, single episode, severe without psychotic features
F32.3	Major depressive disorder, single episode, severe with psychotic features
F32.4	Major depressive disorder, single episode, in partial remission
F32.5	Major depressive disorder, single episode, in full remission
F32.9	Major depressive disorder, single episode, unspecified
F33	Major depressive disorder, recurrent
F33.0	Major depressive disorder, recurrent, mild
F33.1	Major depressive disorder, recurrent, moderate
F33.2	Major depressive disorder, recurrent severe without psychotic features
F33.3	Major depressive disorder, recurrent, severe with psychotic symptoms
F33.4	Major depressive disorder, recurrent, in remission
F33.40	Major depressive disorder, recurrent, in remission, unspecified
F33.41	Major depressive disorder, recurrent, in partial remission
F33.42	Major depressive disorder, recurrent, in full remission
F33.9	Major depressive disorder, recurrent, unspecified
F40.01	Agoraphobia with panic disorder
F40.1	Social phobias
F40.10	Social phobia, unspecified
F40.11	Social phobia, generalized
F41.0	Panic disorder [episodic paroxysmal anxiety]
F41.1	Generalized anxiety disorder
F41.8	Other specified anxiety disorders