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PERINDOPRIL ERBUMINE (PERINDOPRIL ERBUMINE)
- Hypertension
- Myocardial infarction prevention
2 mg tablet
- 1 tablet (2 mg) by oral route 2 times per day
4 mg tablet
- 1 tablet (4 mg) by oral route once daily
8 mg tablet
- 1 tablet (8 mg) by oral route once daily
Hypertension
- 1 tablet (2 mg) by oral route 2 times per day
- 2 tablets (4 mg) by oral route once daily
- 1 tablet (4 mg) by oral route once daily
- 1 tablet (4 mg) by oral route 2 times per day
- 2 tablets (4 mg) by oral route 2 times per day
- 2 tablets (8 mg) by oral route 2 times per day
- 1 tablet (8 mg) by oral route 2 times per day
- 2 tablets (8 mg) by oral route once daily
- 1 tablet (8 mg) by oral route once daily
Myocardial infarction prevention
- 2 tablets (4 mg) by oral route once daily
- 1 tablet (4 mg) by oral route once daily
- 2 tablets (8 mg) by oral route once daily
- 1 tablet (8 mg) by oral route once daily
- None
Contraindicated
- Amturnide
- aliskiren-hydrochlorothiazide
- aliskiren-amlodipine
- aliskiren-amlodipin-hcthiazide
- aliskiren
- Curad Enema
- Disposable Enema
- Enema
- Enema Disposable
- Fleet Enema
- Fleet Enema Extra
- Fleet Pediatric
- lithium carbonate
- lithium citrate
- Lithobid
- Oral Saline Laxative
- Osmoprep
- Phosphate Laxative
- Preparation Cleansing
- Ready-to-use Enema
- sod phos mono-sod phos dibasic
- sodium phosphates
- Tekamlo
- Tekturna
- Tekturna Hct
Severe
Moderate
- Alka-seltzer Plus Night
- Alka-seltzer Pm
- Anacin
- Anacin Maximum Strength
- Analgesic
- Angeliq
- Antacid & Pain Relief
- ASA-acetaminophen-caff-buffers
- ASA-acetaminophen-salicyl-caff
- Ascomp With Codeine
- Aspir-trin
- aspirin
- aspirin, buffered
- aspirin-acetaminophen-caffeine
- aspirin-caffeine
- aspirin-diphenhydramine
- aspirin-diphenhydramine citrat
- aspirin-sod bicarb-citric acid
- Azasan
- azathioprine
- azathioprine sodium
- Back & Body Pain Reliever
- Bactrim
- Bactrim Ds
- Bayer Advanced
- Bayer Aspirin
- Bayer Aspirin (with Caffeine)
- Bayer Back & Body
- Bayer Plus Extra Strength
- Bayer Pm
- Bc
- Alka-seltzer Plus Day-night
- Alka-seltzer Plus Cold (pe)
- Alka-seltzer Plus C/c(pe,dm)
- Alka-seltzer Original
- Alka-seltzer Extra Strength
- Alka-seltzer
- Added Strength Pain Reliever
- Added Strength Headache Relief
- Bc Arthritis
- Beyaz
- Buffered Aspirin
- Bufferin
- bumetanide
- Butalbital Compound W/codeine
- Butalbital Compound-codeine
- butalbital-aspirin-caffeine
- carisoprodol-ASA-codeine
- carisoprodol-aspirin
- chlorphen-phenyleph-DM-aspirin
- chlorphenir-phenylephrn-aspirn
- codeine-butalbital-ASA-caff
- Cold Relief
- Cold Relief Plus
- Demadex
- dihydrocodeine-aspirin-caff
- doxylamine-phenylep-DM-aspirin
- drospirenone-e.estradiol-lm.FA
- drospirenone-estradiol
- drospirenone-ethinyl estradiol
- E.c. Prin
- Ecotrin
- Efferves Pain Relief Antacid
- Effervescent Antacid
- Effervescent Pain Relief
- Effervescent Pain Reliever
- Endodan
- ethacrynate sodium
- Excedrin Extra Strength
- Excedrin Migraine
- Extra Strength Bayer
- Fiorinal
- Fiorinal-codeine #3
- furosemide
- Gianvi (28)
- Goody's Extra Strength
- Goody's Migraine Relief
- Headache Formula
- Headache Formula Added Str
- Headache Relief
- Imuran
- Lasix
- Levacet
- Lite Coat Aspirin
- Loryna (28)
- Medi-seltzer
- mercaptopurine
- Migraine Formula
- Migraine Pain Reliever
- Migraine Relief
- Ocella
- Orphenadrine Compound Forte
- Orphenadrine Compound-ds
- orphenadrine-ASA-caffeine
- oxycodone-aspirin
- Pain Relief
- Pain Relief Extra Strength
- Pain Reliever
- Pain Reliever Extra Strength
- Pain Reliever Plus
- Pain-off
- Pamprin Max
- PE-DM-ASA/doxyla-PE-DM-ASA
- Percodan
- Primsol
- Purinethol
- Safyral
- Sodium Edecrin
- sulfamethoxazole-trimethoprim
- Sulfatrim
- Super Pain Relief
- Syeda
- Synalgos-dc
- torsemide
- Tri-buffered Aspirin
- trimethoprim
- Vanquish
- Vestura (28)
- Yasmin (28)
- Yaz 28
- Zarah
- Angioedema
- Hereditary angioedema
- Pregnancy
Contraindicated
- Hyperkalemia
- Hypotension
- Neutropenic disorder
Severe
Moderate
- Bone marrow depression
- Cerebrovascular insufficiency
- Disease of liver
- Kidney disease with reduction in GFR
- Renal artery stenosis
PERINDOPRIL ERBUMINE (PERINDOPRIL ERBUMINE)
- Hypertension
- Myocardial infarction prevention
- None
- Back pain
- Cough
- Dizziness
More Frequent
Severe
Less Severe
- Hypotension
- Increased alanine transaminase
- Arthralgias
- Fever
- General weakness
- Headache disorder
- Myalgias
- Skin rash
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute pancreatitis
- Acute renal failure
- Agranulocytosis
- Anaphylaxis
- Anemia
- Angioedema
- Aplastic anemia
- Eosinophilia
- Eosinophilic pneumonia
- Exfoliative dermatitis
- Head and neck angioedema
- Hemolytic anemia
- Hepatic failure
- Hepatitis
- Hyperkalemia
- Hyponatremia
- Increased aspartate transaminase
- Intestinal angioedema
- Nephritis
- Neutropenic disorder
- Pancytopenia
- Thrombocytopenic disorder
- Vasculitis
Less Severe
- Acute abdominal pain
- Pemphigus
- Psoriasis
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Perindopril
Safety and efficacy not established.
- 1 Day – 18 Years
- Safety and efficacy not established.
Perindopril
- Severity Level:
1
- Additional Notes: Fetal death/morbidity w/use in 2nd & 3rd trimester, stop when pregnancy detected
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Perindopril
Insufficient human data available, drug excreted in rat studies
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available, drug excreted in rat studies |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Perindopril
Renal-Monitor for increased serum creatinine. Metabolic-Monitor for hyperkalemia. Cardiovascular-Minimize dose to decrease dizziness and falls. Limited safety information with doses greater than 8 mg/day.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- Perindopril can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. It is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. If you are planning pregnancy, become pregnant, or think you may be pregnant, tell your doctor right away.
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
Formulary Reference Tool