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Drug overview for CEFUROXIME SODIUM (cefuroxime sodium):
Generic name: CEFUROXIME SODIUM (SEF-ue-ROX-eem)
Drug class: Beta-Lactams
Therapeutic class: Anti-Infective Agents
Cefuroxime is a semisynthetic, second generation cephalosporin antibiotic.
Cefuroxime axetil is used orally for the treatment of mild to moderate respiratory tract infections (i.e., acute maxillary sinusitis, acute bacterial exacerbations of chronic bronchitis) caused by susceptible bacteria; acute bacterial otitis media; mild to moderate pharyngitis and tonsillitis caused by Streptococcus pyogenes (group A beta-hemolytic streptococci); uncomplicated skin and skin structure infections caused by Staphylococcus aureus (including beta-lactamase-producing strains) or S. pyogenes; and uncomplicated urinary tract infections caused by Escherichia coli or Klebsiella pneumoniae. Cefuroxime axetil also is used orally for the treatment of Lyme disease and has been used for the treatment of uncomplicated gonorrhea.
Cefuroxime sodium is used parenterally in the treatment of lower respiratory tract infections (including pneumonia), skin and skin structure infections, genitourinary tract infections, bone and joint infections, septicemia, and meningitis caused by susceptible organisms. Cefuroxime sodium also is used parenterally for perioperative prophylaxis. Because cefuroxime, like other second generation cephalosporins, generally is less active against susceptible gram-positive cocci than are first generation cephalosporins, most clinicians state that cefuroxime probably should not be used in the treatment of infections caused by gram-positive bacteria when a penicillin or a first generation cephalosporin could be used.
In addition, because cefuroxime generally is less active in vitro against Enterobacteriaceae than third generation cephalosporins, some clinicians state that a third generation drug such as cefotaxime or ceftriaxone generally is preferred if a parenteral cephalosporin is indicated in the treatment of infections known or suspected to be caused by these gram-negative bacteria. When available, consider culture and susceptibility information in selecting or modifying antibacterial therapy. In the treatment of known or suspected sepsis or the treatment of other serious infections when the causative organism is unknown, concomitant therapy with an aminoglycoside may be indicated.
Generic name: CEFUROXIME SODIUM (SEF-ue-ROX-eem)
Drug class: Beta-Lactams
Therapeutic class: Anti-Infective Agents
Cefuroxime is a semisynthetic, second generation cephalosporin antibiotic.
Cefuroxime axetil is used orally for the treatment of mild to moderate respiratory tract infections (i.e., acute maxillary sinusitis, acute bacterial exacerbations of chronic bronchitis) caused by susceptible bacteria; acute bacterial otitis media; mild to moderate pharyngitis and tonsillitis caused by Streptococcus pyogenes (group A beta-hemolytic streptococci); uncomplicated skin and skin structure infections caused by Staphylococcus aureus (including beta-lactamase-producing strains) or S. pyogenes; and uncomplicated urinary tract infections caused by Escherichia coli or Klebsiella pneumoniae. Cefuroxime axetil also is used orally for the treatment of Lyme disease and has been used for the treatment of uncomplicated gonorrhea.
Cefuroxime sodium is used parenterally in the treatment of lower respiratory tract infections (including pneumonia), skin and skin structure infections, genitourinary tract infections, bone and joint infections, septicemia, and meningitis caused by susceptible organisms. Cefuroxime sodium also is used parenterally for perioperative prophylaxis. Because cefuroxime, like other second generation cephalosporins, generally is less active against susceptible gram-positive cocci than are first generation cephalosporins, most clinicians state that cefuroxime probably should not be used in the treatment of infections caused by gram-positive bacteria when a penicillin or a first generation cephalosporin could be used.
In addition, because cefuroxime generally is less active in vitro against Enterobacteriaceae than third generation cephalosporins, some clinicians state that a third generation drug such as cefotaxime or ceftriaxone generally is preferred if a parenteral cephalosporin is indicated in the treatment of infections known or suspected to be caused by these gram-negative bacteria. When available, consider culture and susceptibility information in selecting or modifying antibacterial therapy. In the treatment of known or suspected sepsis or the treatment of other serious infections when the causative organism is unknown, concomitant therapy with an aminoglycoside may be indicated.
DRUG IMAGES
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The following indications for CEFUROXIME SODIUM (cefuroxime sodium) have been approved by the FDA:
Indications:
Bacterial meningitis
Bacterial pneumonia
Bacterial sepsis
Bacterial urinary tract infection
Bone infection
E. coli septicemia
E. coli urinary tract infection
Escherichia coli pneumonia
H. influenzae meningitis
Haemophilus influenzae pneumonia
Haemophilus septicemia
Infectious disorder of joint
Klebsiella pneumonia
Klebsiella pneumoniae septicemia
Klebsiella urinary tract infection
Open heart surgery infection prevention
Prevention of perioperative infection
Skin and skin structure E. coli infection
Skin and skin structure Enterobacter infection
Skin and skin structure infection
Skin and skin structure Klebsiella infection
Skin and skin structure Streptococcus pyogenes infection
Staphylococcal meningitis
Staphylococcal pneumonia
Staphylococcal septicemia
Staphylococcus aureus joint infection
Staphylococcus aureus osteomyelitis
Staphylococcus aureus skin and skin structure infection
Streptococcal meningitis
Streptococcal pneumonia
Streptococcal septicemia
Professional Synonyms:
Bacteremia with sepsis
Bacterial septicemia
E. coli pneumonia
E. coli sepsis
E. coli UTI
Escherichia coli sepsis
Escherichia coli septicemia
H. flu meningitis
H. flu pneumonia
H. influenzae pneumonia
Haemophilus influenzae meningitis
Hemophilus influenzae pneumonia
Infection of skin and/or subcutaneous tissue
Infection prophylaxis for open heart surgery
Influenza Bacillus pneumonia
Influenzae Bacillus meningitis
Joint infection due to Staphylococcus aureus
Joint infection due to Staphylococcus pyogenes aureus
Joint infection
Klebsiella UTI
Meningitis due to Haemophilus influenzae
Meningitis due to Hemophilus influenzae
Meningitis due to Staphylococcus species
Meningitis due to Staphylococcus spp.
Osteomyelitis due to Staphylococcus aureus
Osteomyelitis due to Staphylococcus pyogenes aureus
Perioperative infection prophylaxis
Pfeiffer's Bacillus meningitis
Pfeiffer's Bacillus pneumonia
Pneumonia due to E. coli
Pneumonia due to Escherichia coli
Pneumonia due to Haemophilus influenzae
Pneumonia due to Klebsiella species
Pneumonia due to Klebsiella spp.
Pneumonia due to Staphylococcus species
Pneumonia due to Staphylococcus spp.
Pneumonia due to Streptococcus species
Pneumonia due to Streptococcus spp.
Pyogenic bone infection due to Staphylococcus aureus
Sepsis due to Haemophilus species
Sepsis due to Klebsiella pneumoniae
Septicemia due to Haemophilus species
Septicemia due to Haemophilus spp.
Septicemia due to Hemophilus species
Septicemia due to Klebsiella pneumoniae
Septicemia due to Staphylococcus species
Septicemia due to Staphylococcus spp.
Skin & skin soft tissue Streptococcus pyogenes infection
Skin and skin soft tissue Enterobacter infection
Skin and skin soft tissue Escherichia coli infection
Skin and skin soft tissue infection due to Aerobacter
Skin and skin soft tissue infection due to Enterobacter
Skin and skin soft tissue infection due to Klebsiella
Skin and skin soft tissue Staphylococcus aureus infection
Skin and soft tissue skin infection
Staphylococcal sepsis
Streptococcal sepsis
Urinary tract infection due to Escherichia coli
Urinary tract infection due to Klebsiella species
Indications:
Bacterial meningitis
Bacterial pneumonia
Bacterial sepsis
Bacterial urinary tract infection
Bone infection
E. coli septicemia
E. coli urinary tract infection
Escherichia coli pneumonia
H. influenzae meningitis
Haemophilus influenzae pneumonia
Haemophilus septicemia
Infectious disorder of joint
Klebsiella pneumonia
Klebsiella pneumoniae septicemia
Klebsiella urinary tract infection
Open heart surgery infection prevention
Prevention of perioperative infection
Skin and skin structure E. coli infection
Skin and skin structure Enterobacter infection
Skin and skin structure infection
Skin and skin structure Klebsiella infection
Skin and skin structure Streptococcus pyogenes infection
Staphylococcal meningitis
Staphylococcal pneumonia
Staphylococcal septicemia
Staphylococcus aureus joint infection
Staphylococcus aureus osteomyelitis
Staphylococcus aureus skin and skin structure infection
Streptococcal meningitis
Streptococcal pneumonia
Streptococcal septicemia
Professional Synonyms:
Bacteremia with sepsis
Bacterial septicemia
E. coli pneumonia
E. coli sepsis
E. coli UTI
Escherichia coli sepsis
Escherichia coli septicemia
H. flu meningitis
H. flu pneumonia
H. influenzae pneumonia
Haemophilus influenzae meningitis
Hemophilus influenzae pneumonia
Infection of skin and/or subcutaneous tissue
Infection prophylaxis for open heart surgery
Influenza Bacillus pneumonia
Influenzae Bacillus meningitis
Joint infection due to Staphylococcus aureus
Joint infection due to Staphylococcus pyogenes aureus
Joint infection
Klebsiella UTI
Meningitis due to Haemophilus influenzae
Meningitis due to Hemophilus influenzae
Meningitis due to Staphylococcus species
Meningitis due to Staphylococcus spp.
Osteomyelitis due to Staphylococcus aureus
Osteomyelitis due to Staphylococcus pyogenes aureus
Perioperative infection prophylaxis
Pfeiffer's Bacillus meningitis
Pfeiffer's Bacillus pneumonia
Pneumonia due to E. coli
Pneumonia due to Escherichia coli
Pneumonia due to Haemophilus influenzae
Pneumonia due to Klebsiella species
Pneumonia due to Klebsiella spp.
Pneumonia due to Staphylococcus species
Pneumonia due to Staphylococcus spp.
Pneumonia due to Streptococcus species
Pneumonia due to Streptococcus spp.
Pyogenic bone infection due to Staphylococcus aureus
Sepsis due to Haemophilus species
Sepsis due to Klebsiella pneumoniae
Septicemia due to Haemophilus species
Septicemia due to Haemophilus spp.
Septicemia due to Hemophilus species
Septicemia due to Klebsiella pneumoniae
Septicemia due to Staphylococcus species
Septicemia due to Staphylococcus spp.
Skin & skin soft tissue Streptococcus pyogenes infection
Skin and skin soft tissue Enterobacter infection
Skin and skin soft tissue Escherichia coli infection
Skin and skin soft tissue infection due to Aerobacter
Skin and skin soft tissue infection due to Enterobacter
Skin and skin soft tissue infection due to Klebsiella
Skin and skin soft tissue Staphylococcus aureus infection
Skin and soft tissue skin infection
Staphylococcal sepsis
Streptococcal sepsis
Urinary tract infection due to Escherichia coli
Urinary tract infection due to Klebsiella species
The following dosing information is available for CEFUROXIME SODIUM (cefuroxime sodium):
Dosage of cefuroxime axetil is expressed in terms of cefuroxime.
Dosage of cefuroxime sodium also is expressed in terms of cefuroxime and is identical for IM or IV administration.
The usual parenteral adult dosage of cefuroxime given as cefuroxime sodium is 750 mg to 1.5 g every 8 hours for 5-10 days. Severe or complicated infections in adults generally require 1.5
g every 8 hours and life-threatening infections or infections caused by less susceptible organisms may require 1.5 g every 6 hours.
For the treatment of most susceptible infections (except bone and joint infections or meningitis) in children >=3 months of age, the manufacturer recommends a cefuroxime dosage of 50-100 mg/kg daily given IM or IV in equally divided doses every 6-8 hours; the manufacturer states that 100 mg/kg daily (not to exceed the maximum adult dosage) should be given IM or IV for more severe infections. The IM or IV dosage of cefuroxime recommended by the manufacturers for the treatment of bone and joint infections in children >=3 months of age is 150 mg/kg daily in 3 divided doses every 8 hours.
The American Academy of Pediatrics (AAP) recommends that neonates with a gestational age (GA) of <=31 weeks and 6 days and a postnatal age (PNA) of <7 days receive IM or IV cefuroxime in a dosage of 50 mg/kg every 12 hours. Neonates with GA <=31 weeks and 6 days and PNA of 7-28 days should receive a dosage of 50 mg/kg every 8 hours. AAP recommends that neonates with GA >=32 weeks and PNA of <=7 days receive IM or IV cefuroxime in a dosage of 50 mg/kg every 12 hours.
Neonates with GA >=32 weeks and PNA of 8-28 days should receive a dosage of 50 mg/kg every 8 hours.
For pediatric patients beyond the neonatal period, the AAP recommends an IM or IV cefuroxime dosage of 100-150 mg/kg daily (maximum 6 g/day) given in 3 equally divided doses. These clinicians recommend that children beyond the neonatal period receive oral cefuroxime in a dosage of 20-30 mg/kg daily (maximum 1 g/day) in 2 equally divided doses for the treatment of mild to moderate infections. AAP recommends an oral cefuroxime dosage of up to 100 mg/kg daily (maximum 3 g/day) in 3 divided doses for the treatment of bone or joint infections in pediatric patients beyond the neonatal period.
Dosage of cefuroxime sodium also is expressed in terms of cefuroxime and is identical for IM or IV administration.
The usual parenteral adult dosage of cefuroxime given as cefuroxime sodium is 750 mg to 1.5 g every 8 hours for 5-10 days. Severe or complicated infections in adults generally require 1.5
g every 8 hours and life-threatening infections or infections caused by less susceptible organisms may require 1.5 g every 6 hours.
For the treatment of most susceptible infections (except bone and joint infections or meningitis) in children >=3 months of age, the manufacturer recommends a cefuroxime dosage of 50-100 mg/kg daily given IM or IV in equally divided doses every 6-8 hours; the manufacturer states that 100 mg/kg daily (not to exceed the maximum adult dosage) should be given IM or IV for more severe infections. The IM or IV dosage of cefuroxime recommended by the manufacturers for the treatment of bone and joint infections in children >=3 months of age is 150 mg/kg daily in 3 divided doses every 8 hours.
The American Academy of Pediatrics (AAP) recommends that neonates with a gestational age (GA) of <=31 weeks and 6 days and a postnatal age (PNA) of <7 days receive IM or IV cefuroxime in a dosage of 50 mg/kg every 12 hours. Neonates with GA <=31 weeks and 6 days and PNA of 7-28 days should receive a dosage of 50 mg/kg every 8 hours. AAP recommends that neonates with GA >=32 weeks and PNA of <=7 days receive IM or IV cefuroxime in a dosage of 50 mg/kg every 12 hours.
Neonates with GA >=32 weeks and PNA of 8-28 days should receive a dosage of 50 mg/kg every 8 hours.
For pediatric patients beyond the neonatal period, the AAP recommends an IM or IV cefuroxime dosage of 100-150 mg/kg daily (maximum 6 g/day) given in 3 equally divided doses. These clinicians recommend that children beyond the neonatal period receive oral cefuroxime in a dosage of 20-30 mg/kg daily (maximum 1 g/day) in 2 equally divided doses for the treatment of mild to moderate infections. AAP recommends an oral cefuroxime dosage of up to 100 mg/kg daily (maximum 3 g/day) in 3 divided doses for the treatment of bone or joint infections in pediatric patients beyond the neonatal period.
Cefuroxime axetil is administered orally. Cefuroxime sodium is administered by IV injection or infusion or by deep IM injection. IV rather than IM administration may be preferred in patients with septicemia or other severe or life-threatening infections or in patients with lowered resistance, particularly if shock is present or impending.
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| CEFUROXIME SOD 750 MG VIAL | Maintenance | Adults infuse 750 mg by intravenous route every 8 hours |
| CEFUROXIME SOD 7.5 GM VIAL | Maintenance | Adults infuse 750 mg by intravenous route every 8 hours |
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| CEFUROXIME SOD 750 MG VIAL | Maintenance | Adults infuse 750 mg by intravenous route every 8 hours |
| CEFUROXIME SOD 7.5 GM VIAL | Maintenance | Adults infuse 750 mg by intravenous route every 8 hours |
The following drug interaction information is available for CEFUROXIME SODIUM (cefuroxime sodium):
There are 1 contraindications.
These drug combinations generally should not be dispensed or administered to the same patient. A manufacturer label warning that indicates the contraindication warrants inclusion of a drug combination in this category, regardless of clinical evidence or lack of clinical evidence to support the contraindication.
| Drug Interaction | Drug Names |
|---|---|
| Live Typhoid Vaccine/Antimicrobials SEVERITY LEVEL: 1-Contraindicated Drug Combination: This drug combination is contraindicated and generally should not be dispensed or administered to the same patient. MECHANISM OF ACTION: The antimicrobial may be active against the organism in the live-vaccine. Antimicrobial therapy may prevent the vaccine organism from replicating enough to trigger an immune response.(1) CLINICAL EFFECTS: Vaccination may be ineffective. PREDISPOSING FACTORS: None determined. PATIENT MANAGEMENT: Do not give oral typhoid vaccine until 72 hours after the last dose of antimicrobial. If possible, to optimize vaccine effectiveness, do not start antibacterial drugs for 72 hours after the last dose of oral typhoid vaccine. A longer interval should be considered for long-acting antimicrobials, such as azithromycin.(3) DISCUSSION: Because antimicrobial therapy may prevent sufficient vaccine-organism replication to generate an immune response, the manufacturer of live-attenuated typhoid vaccine and the Centers for Disease Control (CDC) state that the vaccine should not be administered to patients receiving antimicrobial therapy.(1-3) |
VIVOTIF |
There are 2 severe interactions.
These drug interactions can produce serious consequences in most patients. Actions required for severe interactions include, but are not limited to, discontinuing one or both agents, adjusting dosage, altering administration scheduling, and providing additional patient monitoring. Review the full interaction monograph for more information.
| Drug Interaction | Drug Names |
|---|---|
| Fecal Microbiota Spores/Antibiotics SEVERITY LEVEL: 2-Severe Interaction: Action is required to reduce the risk of severe adverse interaction. MECHANISM OF ACTION: Fecal microbiota spores is a suspension of live bacterial spores, which may be compromised by concurrent use of antibiotics.(1) CLINICAL EFFECTS: Antibiotics may decrease the effectiveness of fecal microbiota spores.(1) PREDISPOSING FACTORS: None determined. PATIENT MANAGEMENT: Antibiotics should not be used concurrently with fecal microbiota spores. Antibacterial treatment should be completed for 2 to 4 days before initiating treatment with fecal microbiota spores.(1) DISCUSSION: Antibiotics may compromise the effectiveness of fecal microbiota spores. |
VOWST |
| Fecal Microbiota/Antibiotics SEVERITY LEVEL: 2-Severe Interaction: Action is required to reduce the risk of severe adverse interaction. MECHANISM OF ACTION: Fecal microbiota is a suspension of live bacteria, which may be compromised by concurrent use of antibiotics.(1) CLINICAL EFFECTS: Antibiotics may decrease the effectiveness of fecal microbiota.(1) PREDISPOSING FACTORS: None determined. PATIENT MANAGEMENT: Antibiotics should not be used concurrently with fecal microbiota. Antibacterial treatment should be completed for 24 to 72 hours before initiating treatment with fecal microbiota. Do not use antibiotics for up to 8 weeks after fecal microbiota.(1) DISCUSSION: Antibiotics may compromise the effectiveness of fecal microbiota. |
REBYOTA |
There are 1 moderate interactions.
The clinician should assess the patient’s characteristics and take action as needed. Actions required for moderate interactions include, but are not limited to, discontinuing one or both agents, adjusting dosage, altering administration.
| Drug Interaction | Drug Names |
|---|---|
| Selected Cephalosporins & Penicillins/Probenecid SEVERITY LEVEL: 3-Moderate Interaction: Assess the risk to the patient and take action as needed. MECHANISM OF ACTION: Probenecid impairs the clearance of some cephalosporins and penicillins via inhibition of renal anion transporters in the proximal tubule.(49) It has also been hypothesized that probenecid may affect tissue distribution of cephalosporins.(1-5) CLINICAL EFFECTS: The concurrent administration of probenecid may result in increased maximum concentration (Cmax), area-under-curve (AUC), and half-life of the cephalosporin or penicillin.(49) While this may improve antibiotic efficacy,(46-48) increased levels may also increase the risk for antibiotic-associated nephrotoxicity.(4) PREDISPOSING FACTORS: Underlying renal dysfunction may increase the risk for nephrotoxicity. PATIENT MANAGEMENT: In patients receiving the combination to improve antibiotic efficacy, monitor for antibiotic adverse effects and consider monitoring renal function. In patients receiving probenecid therapy to prevent or treat hyperuricemia, exposure to the antibiotic will be increased. A decrease in antibiotic dose or frequency may be required. The US manufacturer of piperacillin-tazobactam states probenecid should not be coadministered with piperacillin-tazobactam unless the benefit outweighs the risk.(50) DISCUSSION: Concurrent use of probenecid with a cephalosporin or penicillin may cause an increase in the Cmax, AUC, and an increased elimination half life of the antibiotic.(6-8,49) This may be beneficial or necessary in difficult to treat infections,(46-48) but an increased risk for adverse effects should be expected. Antibiotics not dose adjusted for concurrent use with probenecid may be associated with an increased risk for adverse effects, such as nephrotoxicity. Probenecid administered concurrently with piperacillin-tazobactam prolongs the half-life of piperacillin by 21% and tazobactam by 71%. In a study in 8 healthy males, concurrent administration of probenecid (1 g) with piperacillin (1 g IM) increased piperacillin's Cmax and AUC by 30% and 60%. Renal clearance was reduced by 40%.(51) The cephalosporins affected by probenecid include cefazolin,(9-11) cephacetrile,(12,13) cephaloglycin,(14,15) cephalexin,(16-21) cephradine, (22-23) cefoxitin,(24-28) cefadroxil(29), cefaclor,(23) cefamandole,(30) ceftizoxime,(31,32) cefuroxime,(33,34) cefprozil,(35) cefonicid,(36) cefmetazole,(37) cefmenoxime,(38) and cefditoren.(39) Probenecid has been shown not to affect moxalactam,(4,40,41) ceforanide, (4,42), cefoperazone, ceftazidime(4,34,43) or ceftriaxone.(4) |
ORLYNVAH, PROBENECID, PROBENECID-COLCHICINE |
The following contraindication information is available for CEFUROXIME SODIUM (cefuroxime sodium):
Drug contraindication overview.
*Known hypersensitivity to cefuroxime or other beta-lactam antibacterial drugs (e.g., penicillins, cephalosporins).
*Known hypersensitivity to cefuroxime or other beta-lactam antibacterial drugs (e.g., penicillins, cephalosporins).
There are 0 contraindications.
There are 3 severe contraindications.
Adequate patient monitoring is recommended for safer drug use.
| Severe List |
|---|
| Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min |
| Chronic kidney disease stage 5 (failure) GFr<15 ml/min |
| Clostridioides difficile infection |
There are 1 moderate contraindications.
Clinically significant contraindication, where the condition can be managed or treated before the drug may be given safely.
| Moderate List |
|---|
| Hypoprothrombinemia |
The following adverse reaction information is available for CEFUROXIME SODIUM (cefuroxime sodium):
Adverse reaction overview.
Common adverse effects reported in patients receiving cefuroxime sodium injection include local reactions at IV injection sites, reported in approximately 2% of patients. Common adverse effects reported in >=3% of patients receiving oral cefuroxime axetil include diarrhea, nausea/vomiting, and, in patients receiving the drug for early Lyme disease, Jarisch-Herxheimer reaction and vaginitis.
Common adverse effects reported in patients receiving cefuroxime sodium injection include local reactions at IV injection sites, reported in approximately 2% of patients. Common adverse effects reported in >=3% of patients receiving oral cefuroxime axetil include diarrhea, nausea/vomiting, and, in patients receiving the drug for early Lyme disease, Jarisch-Herxheimer reaction and vaginitis.
There are 37 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
|
Clostridioides difficile infection Eosinophilia Hypersensitivity drug reaction Urticaria |
Kounis syndrome Skin rash |
| Rare/Very Rare |
|---|
|
Abnormal hepatic function tests Acute generalized exanthematous pustulosis Agranulocytosis Anaphylaxis Angioedema Aplastic anemia Cholestasis Cholestatic hepatitis Colitis Cutaneous vasculitis DRESS syndrome Drug-induced hepatitis Encephalopathy Erythema Erythema multiforme Hemolytic anemia Hemorrhage Hypoprothrombinemia Interstitial nephritis Kidney disease with reduction in glomerular filtration rate (GFr) Leukopenia Myocardial ischemia Neutropenic disorder Pancytopenia Seizure disorder Serum sickness Stevens-johnson syndrome Thrombocytopenic disorder Thrombophlebitis Tongue swelling Toxic epidermal necrolysis |
There are 29 less severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
|
Acute abdominal pain Diarrhea Vulvovaginal candidiasis |
Arthralgia Flatulence Irritability Nausea Oral candidiasis Pruritus of skin Sialorrhea Vaginal irritation Vomiting |
| Rare/Very Rare |
|---|
|
Abdominal pain with cramps Anorexia Aphthous stomatitis Candidiasis Chills Cramps Dizziness Drowsy Drug fever Dysgeusia Dyspnea Dysuria Polydipsia Renal pain Tachycardia Trismus Vulvovaginitis |
The following precautions are available for CEFUROXIME SODIUM (cefuroxime sodium):
Safety and efficacy of oral cefuroxime axetil or parenteral cefuroxime sodium in children <3 months of age have not been established. Other cephalosporins accumulate in neonates resulting in prolonged serum half-life. In vitro studies indicate that cefuroxime does not appear to displace bilirubin appreciably from albumin binding sites in neonates.
Safety and efficacy of oral cefuroxime for treatment of acute bacterial maxillary sinusitis in pediatric patients 3 months to 12 years of age have been established based on safety and efficacy of the drug in adults. In addition, use of oral cefuroxime in pediatric patients is supported by pharmacokinetic and safety data in adult and pediatric patients, clinical and microbiologic data from adequate and well-controlled studies of the treatment of acute bacterial maxillary sinusitis in adults and acute otitis media with effusion in pediatric patients, and postmarketing surveillance of adverse effects. Tablets should not be crushed for pediatric administration since the drug has a strong, persistent, bitter taste; vomiting was induced aversively in some children who received crushed tablets.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
Safety and efficacy of oral cefuroxime for treatment of acute bacterial maxillary sinusitis in pediatric patients 3 months to 12 years of age have been established based on safety and efficacy of the drug in adults. In addition, use of oral cefuroxime in pediatric patients is supported by pharmacokinetic and safety data in adult and pediatric patients, clinical and microbiologic data from adequate and well-controlled studies of the treatment of acute bacterial maxillary sinusitis in adults and acute otitis media with effusion in pediatric patients, and postmarketing surveillance of adverse effects. Tablets should not be crushed for pediatric administration since the drug has a strong, persistent, bitter taste; vomiting was induced aversively in some children who received crushed tablets.
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
Reproduction studies in mice and rabbits using cefuroxime sodium in dosages up to 6 and 2 times the maximum recommended human dosage based on mg/m2, respectively, and reproduction studies in mice and rats using cefuroxime axetil in dosages up to 14 and 9 times, respectively, the maximum recommended human dosage based on mg/m2 have not revealed evidence of impaired fertility or harm to the fetus. There are no adequate and controlled studies to date using cefuroxime in pregnant women, and cefuroxime should be used during pregnancy only when clearly needed. The manufacturer of cefuroxime axetil states that while available studies cannot definitively establish the absence of risk, published data from epidemiologic studies, case series, and case reports over several decades have not identified an association with the use of cephalosporins (including cefuroxime axetil) during pregnancy and major birth defects, miscarriage, or other adverse maternal or fetal outcomes.
Because cefuroxime is distributed into milk, cefuroxime sodium should be used with caution in nursing women. Based on published case reports, the estimated breastfed infant dose is expected to be <1% of the adult dose. No data are available on the effects of the drug on the breastfed infant or the effects of the drug on milk production. Consider the developmental and health benefits of breastfeeding along with the mother's clinical need for cefuroxime and any potential adverse effects on the breastfed infant from cefuroxime or from the underlying maternal condition.
Of the 1,914 subjects who received parenteral cefuroxime in 24 clinical studies, 47% were >=65 years of age while 22% were >=75 years of age. Of the total number of subjects who received cefuroxime axetil in 20 clinical trials, 375 were >=65 years of age while 151 were >=75 years of age. No overall differences in safety or effectiveness of oral or parenteral cefuroxime were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between geriatric patients and younger adults; however, greater susceptibility of some older individuals to effects of the drug cannot be ruled out.
Cefuroxime is substantially eliminated by kidneys; the risk of toxicity may be greater in those with impaired renal function. Limited data indicate that mean serum elimination half-life of cefuroxime is prolonged in geriatric patients (mean age: 83.9 years) who have a mean creatinine clearance of approximately 35 mL/minute. Despite this prolonged elimination, the manufacturers state that age-based dosage adjustment does not appear to be necessary. However, because geriatric patients are more likely to have decreased renal function, dosage should be selected with caution in these patients and monitoring of renal function may be useful.
Cefuroxime is substantially eliminated by kidneys; the risk of toxicity may be greater in those with impaired renal function. Limited data indicate that mean serum elimination half-life of cefuroxime is prolonged in geriatric patients (mean age: 83.9 years) who have a mean creatinine clearance of approximately 35 mL/minute. Despite this prolonged elimination, the manufacturers state that age-based dosage adjustment does not appear to be necessary. However, because geriatric patients are more likely to have decreased renal function, dosage should be selected with caution in these patients and monitoring of renal function may be useful.
The following prioritized warning is available for CEFUROXIME SODIUM (cefuroxime sodium):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for CEFUROXIME SODIUM (cefuroxime sodium)'s list of indications:
| Bacterial meningitis | |
| G00.9 | Bacterial meningitis, unspecified |
| G01 | Meningitis in bacterial diseases classified elsewhere |
| G04.2 | Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified |
| Bacterial pneumonia | |
| J15.9 | Unspecified bacterial pneumonia |
| Bacterial sepsis | |
| A02.1 | Salmonella sepsis |
| A20.7 | Septicemic plague |
| A22.7 | Anthrax sepsis |
| A26.7 | Erysipelothrix sepsis |
| A32.7 | Listerial sepsis |
| A40 | Streptococcal sepsis |
| A40.0 | Sepsis due to streptococcus, group A |
| A40.1 | Sepsis due to streptococcus, group B |
| A40.3 | Sepsis due to streptococcus pneumoniae |
| A40.8 | Other streptococcal sepsis |
| A40.9 | Streptococcal sepsis, unspecified |
| A41 | Other sepsis |
| A41.0 | Sepsis due to staphylococcus aureus |
| A41.01 | Sepsis due to methicillin susceptible staphylococcus aureus |
| A41.02 | Sepsis due to methicillin resistant staphylococcus aureus |
| A41.1 | Sepsis due to other specified staphylococcus |
| A41.2 | Sepsis due to unspecified staphylococcus |
| A41.3 | Sepsis due to hemophilus influenzae |
| A41.4 | Sepsis due to anaerobes |
| A41.5 | Sepsis due to other gram-negative organisms |
| A41.50 | Gram-negative sepsis, unspecified |
| A41.51 | Sepsis due to escherichia coli [e. coli] |
| A41.52 | Sepsis due to pseudomonas |
| A41.53 | Sepsis due to serratia |
| A41.54 | Sepsis due to acinetobacter baumannii |
| A41.59 | Other gram-negative sepsis |
| A41.8 | Other specified sepsis |
| A41.81 | Sepsis due to enterococcus |
| A41.89 | Other specified sepsis |
| A41.9 | Sepsis, unspecified organism |
| A42.7 | Actinomycotic sepsis |
| A54.86 | Gonococcal sepsis |
| O03.37 | Sepsis following incomplete spontaneous abortion |
| O08.82 | Sepsis following ectopic and molar pregnancy |
| O85 | Puerperal sepsis |
| O86.04 | Sepsis following an obstetrical procedure |
| P36 | Bacterial sepsis of newborn |
| P36.0 | Sepsis of newborn due to streptococcus, group B |
| P36.1 | Sepsis of newborn due to other and unspecified streptococci |
| P36.10 | Sepsis of newborn due to unspecified streptococci |
| P36.19 | Sepsis of newborn due to other streptococci |
| P36.2 | Sepsis of newborn due to staphylococcus aureus |
| P36.3 | Sepsis of newborn due to other and unspecified staphylococci |
| P36.30 | Sepsis of newborn due to unspecified staphylococci |
| P36.39 | Sepsis of newborn due to other staphylococci |
| P36.4 | Sepsis of newborn due to escherichia coli |
| P36.5 | Sepsis of newborn due to anaerobes |
| P36.8 | Other bacterial sepsis of newborn |
| P36.9 | Bacterial sepsis of newborn, unspecified |
| R65.2 | Severe sepsis |
| T81.12 | Postprocedural septic shock |
| T81.12xA | Postprocedural septic shock, initial encounter |
| T81.44 | Sepsis following a procedure |
| T81.44xA | Sepsis following a procedure, initial encounter |
| Bacterial urinary tract infection | |
| N30.0 | Acute cystitis |
| N30.00 | Acute cystitis without hematuria |
| N30.01 | Acute cystitis with hematuria |
| N30.9 | Cystitis, unspecified |
| N30.90 | Cystitis, unspecified without hematuria |
| N30.91 | Cystitis, unspecified with hematuria |
| N39.0 | Urinary tract infection, site not specified |
| O23.0 | Infections of kidney in pregnancy |
| O23.00 | Infections of kidney in pregnancy, unspecified trimester |
| O23.01 | Infections of kidney in pregnancy, first trimester |
| O23.02 | Infections of kidney in pregnancy, second trimester |
| O23.03 | Infections of kidney in pregnancy, third trimester |
| O23.1 | Infections of bladder in pregnancy |
| O23.10 | Infections of bladder in pregnancy, unspecified trimester |
| O23.11 | Infections of bladder in pregnancy, first trimester |
| O23.12 | Infections of bladder in pregnancy, second trimester |
| O23.13 | Infections of bladder in pregnancy, third trimester |
| O23.2 | Infections of urethra in pregnancy |
| O23.20 | Infections of urethra in pregnancy, unspecified trimester |
| O23.21 | Infections of urethra in pregnancy, first trimester |
| O23.22 | Infections of urethra in pregnancy, second trimester |
| O23.23 | Infections of urethra in pregnancy, third trimester |
| O23.3 | Infections of other parts of urinary tract in pregnancy |
| O23.30 | Infections of other parts of urinary tract in pregnancy, unspecified trimester |
| O23.31 | Infections of other parts of urinary tract in pregnancy, first trimester |
| O23.32 | Infections of other parts of urinary tract in pregnancy, second trimester |
| O23.33 | Infections of other parts of urinary tract in pregnancy, third trimester |
| O23.4 | Unspecified infection of urinary tract in pregnancy |
| O23.40 | Unspecified infection of urinary tract in pregnancy, unspecified trimester |
| O23.41 | Unspecified infection of urinary tract in pregnancy, first trimester |
| O23.42 | Unspecified infection of urinary tract in pregnancy, second trimester |
| O23.43 | Unspecified infection of urinary tract in pregnancy, third trimester |
| O23.90 | Unspecified genitourinary tract infection in pregnancy, unspecified trimester |
| O23.91 | Unspecified genitourinary tract infection in pregnancy, first trimester |
| O23.92 | Unspecified genitourinary tract infection in pregnancy, second trimester |
| O23.93 | Unspecified genitourinary tract infection in pregnancy, third trimester |
| P39.3 | Neonatal urinary tract infection |
| T83 | Complications of genitourinary prosthetic devices, implants and grafts |
| T83.5 | Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system |
| T83.51 | Infection and inflammatory reaction due to urinary catheter |
| T83.59 | Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system |
| T83.6 | Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract |
| Bone infection | |
| H05.02 | Osteomyelitis of orbit |
| H05.021 | Osteomyelitis of right orbit |
| H05.022 | Osteomyelitis of left orbit |
| H05.023 | Osteomyelitis of bilateral orbits |
| H05.029 | Osteomyelitis of unspecified orbit |
| H70 | Mastoiditis and related conditions |
| H70.0 | Acute mastoiditis |
| H70.00 | Acute mastoiditis without complications |
| H70.001 | Acute mastoiditis without complications, right ear |
| H70.002 | Acute mastoiditis without complications, left ear |
| H70.003 | Acute mastoiditis without complications, bilateral |
| H70.009 | Acute mastoiditis without complications, unspecified ear |
| H70.01 | Subperiosteal abscess of mastoid |
| H70.011 | Subperiosteal abscess of mastoid, right ear |
| H70.012 | Subperiosteal abscess of mastoid, left ear |
| H70.013 | Subperiosteal abscess of mastoid, bilateral |
| H70.019 | Subperiosteal abscess of mastoid, unspecified ear |
| H70.09 | Acute mastoiditis with other complications |
| H70.091 | Acute mastoiditis with other complications, right ear |
| H70.092 | Acute mastoiditis with other complications, left ear |
| H70.093 | Acute mastoiditis with other complications, bilateral |
| H70.099 | Acute mastoiditis with other complications, unspecified ear |
| H70.1 | Chronic mastoiditis |
| H70.10 | Chronic mastoiditis, unspecified ear |
| H70.11 | Chronic mastoiditis, right ear |
| H70.12 | Chronic mastoiditis, left ear |
| H70.13 | Chronic mastoiditis, bilateral |
| H70.2 | Petrositis |
| H70.20 | Unspecified petrositis |
| H70.201 | Unspecified petrositis, right ear |
| H70.202 | Unspecified petrositis, left ear |
| H70.203 | Unspecified petrositis, bilateral |
| H70.209 | Unspecified petrositis, unspecified ear |
| H70.21 | Acute petrositis |
| H70.211 | Acute petrositis, right ear |
| H70.212 | Acute petrositis, left ear |
| H70.213 | Acute petrositis, bilateral |
| H70.219 | Acute petrositis, unspecified ear |
| H70.22 | Chronic petrositis |
| H70.221 | Chronic petrositis, right ear |
| H70.222 | Chronic petrositis, left ear |
| H70.223 | Chronic petrositis, bilateral |
| H70.229 | Chronic petrositis, unspecified ear |
| H70.8 | Other mastoiditis and related conditions |
| H70.89 | Other mastoiditis and related conditions |
| H70.891 | Other mastoiditis and related conditions, right ear |
| H70.892 | Other mastoiditis and related conditions, left ear |
| H70.893 | Other mastoiditis and related conditions, bilateral |
| H70.899 | Other mastoiditis and related conditions, unspecified ear |
| H70.9 | Unspecified mastoiditis |
| H70.90 | Unspecified mastoiditis, unspecified ear |
| H70.91 | Unspecified mastoiditis, right ear |
| H70.92 | Unspecified mastoiditis, left ear |
| H70.93 | Unspecified mastoiditis, bilateral |
| H75.0 | Mastoiditis in infectious and parasitic diseases classified elsewhere |
| H75.00 | Mastoiditis in infectious and parasitic diseases classified elsewhere, unspecified ear |
| H75.01 | Mastoiditis in infectious and parasitic diseases classified elsewhere, right ear |
| H75.02 | Mastoiditis in infectious and parasitic diseases classified elsewhere, left ear |
| H75.03 | Mastoiditis in infectious and parasitic diseases classified elsewhere, bilateral |
| M46.2 | Osteomyelitis of vertebra |
| M46.20 | Osteomyelitis of vertebra, site unspecified |
| M46.21 | Osteomyelitis of vertebra, occipito-atlanto-axial region |
| M46.22 | Osteomyelitis of vertebra, cervical region |
| M46.23 | Osteomyelitis of vertebra, cervicothoracic region |
| M46.24 | Osteomyelitis of vertebra, thoracic region |
| M46.25 | Osteomyelitis of vertebra, thoracolumbar region |
| M46.26 | Osteomyelitis of vertebra, lumbar region |
| M46.27 | Osteomyelitis of vertebra, lumbosacral region |
| M46.28 | Osteomyelitis of vertebra, sacral and sacrococcygeal region |
| M46.5 | Other infective spondylopathies |
| M46.50 | Other infective spondylopathies, site unspecified |
| M46.51 | Other infective spondylopathies, occipito-atlanto-axial region |
| M46.52 | Other infective spondylopathies, cervical region |
| M46.53 | Other infective spondylopathies, cervicothoracic region |
| M46.54 | Other infective spondylopathies, thoracic region |
| M46.55 | Other infective spondylopathies, thoracolumbar region |
| M46.56 | Other infective spondylopathies, lumbar region |
| M46.57 | Other infective spondylopathies, lumbosacral region |
| M46.58 | Other infective spondylopathies, sacral and sacrococcygeal region |
| M46.59 | Other infective spondylopathies, multiple sites in spine |
| M86 | Osteomyelitis |
| M86.0 | Acute hematogenous osteomyelitis |
| M86.00 | Acute hematogenous osteomyelitis, unspecified site |
| M86.01 | Acute hematogenous osteomyelitis, shoulder |
| M86.011 | Acute hematogenous osteomyelitis, right shoulder |
| M86.012 | Acute hematogenous osteomyelitis, left shoulder |
| M86.019 | Acute hematogenous osteomyelitis, unspecified shoulder |
| M86.02 | Acute hematogenous osteomyelitis, humerus |
| M86.021 | Acute hematogenous osteomyelitis, right humerus |
| M86.022 | Acute hematogenous osteomyelitis, left humerus |
| M86.029 | Acute hematogenous osteomyelitis, unspecified humerus |
| M86.03 | Acute hematogenous osteomyelitis, radius and ulna |
| M86.031 | Acute hematogenous osteomyelitis, right radius and ulna |
| M86.032 | Acute hematogenous osteomyelitis, left radius and ulna |
| M86.039 | Acute hematogenous osteomyelitis, unspecified radius and ulna |
| M86.04 | Acute hematogenous osteomyelitis, hand |
| M86.041 | Acute hematogenous osteomyelitis, right hand |
| M86.042 | Acute hematogenous osteomyelitis, left hand |
| M86.049 | Acute hematogenous osteomyelitis, unspecified hand |
| M86.05 | Acute hematogenous osteomyelitis, femur |
| M86.051 | Acute hematogenous osteomyelitis, right femur |
| M86.052 | Acute hematogenous osteomyelitis, left femur |
| M86.059 | Acute hematogenous osteomyelitis, unspecified femur |
| M86.06 | Acute hematogenous osteomyelitis, tibia and fibula |
| M86.061 | Acute hematogenous osteomyelitis, right tibia and fibula |
| M86.062 | Acute hematogenous osteomyelitis, left tibia and fibula |
| M86.069 | Acute hematogenous osteomyelitis, unspecified tibia and fibula |
| M86.07 | Acute hematogenous osteomyelitis, ankle and foot |
| M86.071 | Acute hematogenous osteomyelitis, right ankle and foot |
| M86.072 | Acute hematogenous osteomyelitis, left ankle and foot |
| M86.079 | Acute hematogenous osteomyelitis, unspecified ankle and foot |
| M86.08 | Acute hematogenous osteomyelitis, other sites |
| M86.09 | Acute hematogenous osteomyelitis, multiple sites |
| M86.1 | Other acute osteomyelitis |
| M86.10 | Other acute osteomyelitis, unspecified site |
| M86.11 | Other acute osteomyelitis, shoulder |
| M86.111 | Other acute osteomyelitis, right shoulder |
| M86.112 | Other acute osteomyelitis, left shoulder |
| M86.119 | Other acute osteomyelitis, unspecified shoulder |
| M86.12 | Other acute osteomyelitis, humerus |
| M86.121 | Other acute osteomyelitis, right humerus |
| M86.122 | Other acute osteomyelitis, left humerus |
| M86.129 | Other acute osteomyelitis, unspecified humerus |
| M86.13 | Other acute osteomyelitis, radius and ulna |
| M86.131 | Other acute osteomyelitis, right radius and ulna |
| M86.132 | Other acute osteomyelitis, left radius and ulna |
| M86.139 | Other acute osteomyelitis, unspecified radius and ulna |
| M86.14 | Other acute osteomyelitis, hand |
| M86.141 | Other acute osteomyelitis, right hand |
| M86.142 | Other acute osteomyelitis, left hand |
| M86.149 | Other acute osteomyelitis, unspecified hand |
| M86.15 | Other acute osteomyelitis, femur |
| M86.151 | Other acute osteomyelitis, right femur |
| M86.152 | Other acute osteomyelitis, left femur |
| M86.159 | Other acute osteomyelitis, unspecified femur |
| M86.16 | Other acute osteomyelitis, tibia and fibula |
| M86.161 | Other acute osteomyelitis, right tibia and fibula |
| M86.162 | Other acute osteomyelitis, left tibia and fibula |
| M86.169 | Other acute osteomyelitis, unspecified tibia and fibula |
| M86.17 | Other acute osteomyelitis, ankle and foot |
| M86.171 | Other acute osteomyelitis, right ankle and foot |
| M86.172 | Other acute osteomyelitis, left ankle and foot |
| M86.179 | Other acute osteomyelitis, unspecified ankle and foot |
| M86.18 | Other acute osteomyelitis, other site |
| M86.19 | Other acute osteomyelitis, multiple sites |
| M86.2 | Subacute osteomyelitis |
| M86.20 | Subacute osteomyelitis, unspecified site |
| M86.21 | Subacute osteomyelitis, shoulder |
| M86.211 | Subacute osteomyelitis, right shoulder |
| M86.212 | Subacute osteomyelitis, left shoulder |
| M86.219 | Subacute osteomyelitis, unspecified shoulder |
| M86.22 | Subacute osteomyelitis, humerus |
| M86.221 | Subacute osteomyelitis, right humerus |
| M86.222 | Subacute osteomyelitis, left humerus |
| M86.229 | Subacute osteomyelitis, unspecified humerus |
| M86.23 | Subacute osteomyelitis, radius and ulna |
| M86.231 | Subacute osteomyelitis, right radius and ulna |
| M86.232 | Subacute osteomyelitis, left radius and ulna |
| M86.239 | Subacute osteomyelitis, unspecified radius and ulna |
| M86.24 | Subacute osteomyelitis, hand |
| M86.241 | Subacute osteomyelitis, right hand |
| M86.242 | Subacute osteomyelitis, left hand |
| M86.249 | Subacute osteomyelitis, unspecified hand |
| M86.25 | Subacute osteomyelitis, femur |
| M86.251 | Subacute osteomyelitis, right femur |
| M86.252 | Subacute osteomyelitis, left femur |
| M86.259 | Subacute osteomyelitis, unspecified femur |
| M86.26 | Subacute osteomyelitis, tibia and fibula |
| M86.261 | Subacute osteomyelitis, right tibia and fibula |
| M86.262 | Subacute osteomyelitis, left tibia and fibula |
| M86.269 | Subacute osteomyelitis, unspecified tibia and fibula |
| M86.27 | Subacute osteomyelitis, ankle and foot |
| M86.271 | Subacute osteomyelitis, right ankle and foot |
| M86.272 | Subacute osteomyelitis, left ankle and foot |
| M86.279 | Subacute osteomyelitis, unspecified ankle and foot |
| M86.28 | Subacute osteomyelitis, other site |
| M86.29 | Subacute osteomyelitis, multiple sites |
| M86.3 | Chronic multifocal osteomyelitis |
| M86.30 | Chronic multifocal osteomyelitis, unspecified site |
| M86.31 | Chronic multifocal osteomyelitis, shoulder |
| M86.311 | Chronic multifocal osteomyelitis, right shoulder |
| M86.312 | Chronic multifocal osteomyelitis, left shoulder |
| M86.319 | Chronic multifocal osteomyelitis, unspecified shoulder |
| M86.32 | Chronic multifocal osteomyelitis, humerus |
| M86.321 | Chronic multifocal osteomyelitis, right humerus |
| M86.322 | Chronic multifocal osteomyelitis, left humerus |
| M86.329 | Chronic multifocal osteomyelitis, unspecified humerus |
| M86.33 | Chronic multifocal osteomyelitis, radius and ulna |
| M86.331 | Chronic multifocal osteomyelitis, right radius and ulna |
| M86.332 | Chronic multifocal osteomyelitis, left radius and ulna |
| M86.339 | Chronic multifocal osteomyelitis, unspecified radius and ulna |
| M86.34 | Chronic multifocal osteomyelitis, hand |
| M86.341 | Chronic multifocal osteomyelitis, right hand |
| M86.342 | Chronic multifocal osteomyelitis, left hand |
| M86.349 | Chronic multifocal osteomyelitis, unspecified hand |
| M86.35 | Chronic multifocal osteomyelitis, femur |
| M86.351 | Chronic multifocal osteomyelitis, right femur |
| M86.352 | Chronic multifocal osteomyelitis, left femur |
| M86.359 | Chronic multifocal osteomyelitis, unspecified femur |
| M86.36 | Chronic multifocal osteomyelitis, tibia and fibula |
| M86.361 | Chronic multifocal osteomyelitis, right tibia and fibula |
| M86.362 | Chronic multifocal osteomyelitis, left tibia and fibula |
| M86.369 | Chronic multifocal osteomyelitis, unspecified tibia and fibula |
| M86.37 | Chronic multifocal osteomyelitis, ankle and foot |
| M86.371 | Chronic multifocal osteomyelitis, right ankle and foot |
| M86.372 | Chronic multifocal osteomyelitis, left ankle and foot |
| M86.379 | Chronic multifocal osteomyelitis, unspecified ankle and foot |
| M86.38 | Chronic multifocal osteomyelitis, other site |
| M86.39 | Chronic multifocal osteomyelitis, multiple sites |
| M86.4 | Chronic osteomyelitis with draining sinus |
| M86.40 | Chronic osteomyelitis with draining sinus, unspecified site |
| M86.41 | Chronic osteomyelitis with draining sinus, shoulder |
| M86.411 | Chronic osteomyelitis with draining sinus, right shoulder |
| M86.412 | Chronic osteomyelitis with draining sinus, left shoulder |
| M86.419 | Chronic osteomyelitis with draining sinus, unspecified shoulder |
| M86.42 | Chronic osteomyelitis with draining sinus, humerus |
| M86.421 | Chronic osteomyelitis with draining sinus, right humerus |
| M86.422 | Chronic osteomyelitis with draining sinus, left humerus |
| M86.429 | Chronic osteomyelitis with draining sinus, unspecified humerus |
| M86.43 | Chronic osteomyelitis with draining sinus, radius and ulna |
| M86.431 | Chronic osteomyelitis with draining sinus, right radius and ulna |
| M86.432 | Chronic osteomyelitis with draining sinus, left radius and ulna |
| M86.439 | Chronic osteomyelitis with draining sinus, unspecified radius and ulna |
| M86.44 | Chronic osteomyelitis with draining sinus, hand |
| M86.441 | Chronic osteomyelitis with draining sinus, right hand |
| M86.442 | Chronic osteomyelitis with draining sinus, left hand |
| M86.449 | Chronic osteomyelitis with draining sinus, unspecified hand |
| M86.45 | Chronic osteomyelitis with draining sinus, femur |
| M86.451 | Chronic osteomyelitis with draining sinus, right femur |
| M86.452 | Chronic osteomyelitis with draining sinus, left femur |
| M86.459 | Chronic osteomyelitis with draining sinus, unspecified femur |
| M86.46 | Chronic osteomyelitis with draining sinus, tibia and fibula |
| M86.461 | Chronic osteomyelitis with draining sinus, right tibia and fibula |
| M86.462 | Chronic osteomyelitis with draining sinus, left tibia and fibula |
| M86.469 | Chronic osteomyelitis with draining sinus, unspecified tibia and fibula |
| M86.47 | Chronic osteomyelitis with draining sinus, ankle and foot |
| M86.471 | Chronic osteomyelitis with draining sinus, right ankle and foot |
| M86.472 | Chronic osteomyelitis with draining sinus, left ankle and foot |
| M86.479 | Chronic osteomyelitis with draining sinus, unspecified ankle and foot |
| M86.48 | Chronic osteomyelitis with draining sinus, other site |
| M86.49 | Chronic osteomyelitis with draining sinus, multiple sites |
| M86.5 | Other chronic hematogenous osteomyelitis |
| M86.50 | Other chronic hematogenous osteomyelitis, unspecified site |
| M86.51 | Other chronic hematogenous osteomyelitis, shoulder |
| M86.511 | Other chronic hematogenous osteomyelitis, right shoulder |
| M86.512 | Other chronic hematogenous osteomyelitis, left shoulder |
| M86.519 | Other chronic hematogenous osteomyelitis, unspecified shoulder |
| M86.52 | Other chronic hematogenous osteomyelitis, humerus |
| M86.521 | Other chronic hematogenous osteomyelitis, right humerus |
| M86.522 | Other chronic hematogenous osteomyelitis, left humerus |
| M86.529 | Other chronic hematogenous osteomyelitis, unspecified humerus |
| M86.53 | Other chronic hematogenous osteomyelitis, radius and ulna |
| M86.531 | Other chronic hematogenous osteomyelitis, right radius and ulna |
| M86.532 | Other chronic hematogenous osteomyelitis, left radius and ulna |
| M86.539 | Other chronic hematogenous osteomyelitis, unspecified radius and ulna |
| M86.54 | Other chronic hematogenous osteomyelitis, hand |
| M86.541 | Other chronic hematogenous osteomyelitis, right hand |
| M86.542 | Other chronic hematogenous osteomyelitis, left hand |
| M86.549 | Other chronic hematogenous osteomyelitis, unspecified hand |
| M86.55 | Other chronic hematogenous osteomyelitis, femur |
| M86.551 | Other chronic hematogenous osteomyelitis, right femur |
| M86.552 | Other chronic hematogenous osteomyelitis, left femur |
| M86.559 | Other chronic hematogenous osteomyelitis, unspecified femur |
| M86.56 | Other chronic hematogenous osteomyelitis, tibia and fibula |
| M86.561 | Other chronic hematogenous osteomyelitis, right tibia and fibula |
| M86.562 | Other chronic hematogenous osteomyelitis, left tibia and fibula |
| M86.569 | Other chronic hematogenous osteomyelitis, unspecified tibia and fibula |
| M86.57 | Other chronic hematogenous osteomyelitis, ankle and foot |
| M86.571 | Other chronic hematogenous osteomyelitis, right ankle and foot |
| M86.572 | Other chronic hematogenous osteomyelitis, left ankle and foot |
| M86.579 | Other chronic hematogenous osteomyelitis, unspecified ankle and foot |
| M86.58 | Other chronic hematogenous osteomyelitis, other site |
| M86.59 | Other chronic hematogenous osteomyelitis, multiple sites |
| M86.6 | Other chronic osteomyelitis |
| M86.60 | Other chronic osteomyelitis, unspecified site |
| M86.61 | Other chronic osteomyelitis, shoulder |
| M86.611 | Other chronic osteomyelitis, right shoulder |
| M86.612 | Other chronic osteomyelitis, left shoulder |
| M86.619 | Other chronic osteomyelitis, unspecified shoulder |
| M86.62 | Other chronic osteomyelitis, humerus |
| M86.621 | Other chronic osteomyelitis, right humerus |
| M86.622 | Other chronic osteomyelitis, left humerus |
| M86.629 | Other chronic osteomyelitis, unspecified humerus |
| M86.63 | Other chronic osteomyelitis, radius and ulna |
| M86.631 | Other chronic osteomyelitis, right radius and ulna |
| M86.632 | Other chronic osteomyelitis, left radius and ulna |
| M86.639 | Other chronic osteomyelitis, unspecified radius and ulna |
| M86.64 | Other chronic osteomyelitis, hand |
| M86.641 | Other chronic osteomyelitis, right hand |
| M86.642 | Other chronic osteomyelitis, left hand |
| M86.649 | Other chronic osteomyelitis, unspecified hand |
| M86.65 | Other chronic osteomyelitis, thigh |
| M86.651 | Other chronic osteomyelitis, right thigh |
| M86.652 | Other chronic osteomyelitis, left thigh |
| M86.659 | Other chronic osteomyelitis, unspecified thigh |
| M86.66 | Other chronic osteomyelitis, tibia and fibula |
| M86.661 | Other chronic osteomyelitis, right tibia and fibula |
| M86.662 | Other chronic osteomyelitis, left tibia and fibula |
| M86.669 | Other chronic osteomyelitis, unspecified tibia and fibula |
| M86.67 | Other chronic osteomyelitis, ankle and foot |
| M86.671 | Other chronic osteomyelitis, right ankle and foot |
| M86.672 | Other chronic osteomyelitis, left ankle and foot |
| M86.679 | Other chronic osteomyelitis, unspecified ankle and foot |
| M86.68 | Other chronic osteomyelitis, other site |
| M86.69 | Other chronic osteomyelitis, multiple sites |
| M86.8 | Other osteomyelitis |
| M86.8x | Other osteomyelitis |
| M86.8x0 | Other osteomyelitis, multiple sites |
| M86.8x1 | Other osteomyelitis, shoulder |
| M86.8x2 | Other osteomyelitis, upper arm |
| M86.8x3 | Other osteomyelitis, forearm |
| M86.8x4 | Other osteomyelitis, hand |
| M86.8x5 | Other osteomyelitis, thigh |
| M86.8x6 | Other osteomyelitis, lower leg |
| M86.8x7 | Other osteomyelitis, ankle and foot |
| M86.8x8 | Other osteomyelitis, other site |
| M86.8x9 | Other osteomyelitis, unspecified sites |
| M86.9 | Osteomyelitis, unspecified |
| E. coli septicemia | |
| A41.51 | Sepsis due to escherichia coli [e. coli] |
| P36.4 | Sepsis of newborn due to escherichia coli |
| E. coli urinary tract infection | |
| B96.2 | Escherichia coli [e. coli ] as the cause of diseases classified elsewhere |
| B96.20 | Unspecified escherichia coli [e. coli] as the cause of diseases classified elsewhere |
| B96.29 | Other escherichia coli [e. coli] as the cause of diseases classified elsewhere |
| N30.0 | Acute cystitis |
| N30.00 | Acute cystitis without hematuria |
| N30.01 | Acute cystitis with hematuria |
| N30.9 | Cystitis, unspecified |
| N30.90 | Cystitis, unspecified without hematuria |
| N30.91 | Cystitis, unspecified with hematuria |
| N39.0 | Urinary tract infection, site not specified |
| O23.0 | Infections of kidney in pregnancy |
| O23.00 | Infections of kidney in pregnancy, unspecified trimester |
| O23.01 | Infections of kidney in pregnancy, first trimester |
| O23.02 | Infections of kidney in pregnancy, second trimester |
| O23.03 | Infections of kidney in pregnancy, third trimester |
| O23.1 | Infections of bladder in pregnancy |
| O23.10 | Infections of bladder in pregnancy, unspecified trimester |
| O23.11 | Infections of bladder in pregnancy, first trimester |
| O23.12 | Infections of bladder in pregnancy, second trimester |
| O23.13 | Infections of bladder in pregnancy, third trimester |
| O23.2 | Infections of urethra in pregnancy |
| O23.20 | Infections of urethra in pregnancy, unspecified trimester |
| O23.21 | Infections of urethra in pregnancy, first trimester |
| O23.22 | Infections of urethra in pregnancy, second trimester |
| O23.23 | Infections of urethra in pregnancy, third trimester |
| O23.3 | Infections of other parts of urinary tract in pregnancy |
| O23.30 | Infections of other parts of urinary tract in pregnancy, unspecified trimester |
| O23.31 | Infections of other parts of urinary tract in pregnancy, first trimester |
| O23.32 | Infections of other parts of urinary tract in pregnancy, second trimester |
| O23.33 | Infections of other parts of urinary tract in pregnancy, third trimester |
| O23.4 | Unspecified infection of urinary tract in pregnancy |
| O23.40 | Unspecified infection of urinary tract in pregnancy, unspecified trimester |
| O23.41 | Unspecified infection of urinary tract in pregnancy, first trimester |
| O23.42 | Unspecified infection of urinary tract in pregnancy, second trimester |
| O23.43 | Unspecified infection of urinary tract in pregnancy, third trimester |
| O23.9 | Unspecified genitourinary tract infection in pregnancy |
| O23.90 | Unspecified genitourinary tract infection in pregnancy, unspecified trimester |
| O23.91 | Unspecified genitourinary tract infection in pregnancy, first trimester |
| O23.92 | Unspecified genitourinary tract infection in pregnancy, second trimester |
| O23.93 | Unspecified genitourinary tract infection in pregnancy, third trimester |
| Escherichia coli pneumonia | |
| J15.5 | Pneumonia due to escherichia coli |
| H. influenzae meningitis | |
| G00.0 | Hemophilus meningitis |
| Haemophilus influenzae pneumonia | |
| J14 | Pneumonia due to hemophilus influenzae |
| Haemophilus septicemia | |
| A41.3 | Sepsis due to hemophilus influenzae |
| Infectious disorder of joint | |
| M00.9 | Pyogenic arthritis, unspecified |
| Klebsiella pneumonia | |
| J15.0 | Pneumonia due to klebsiella pneumoniae |
| Klebsiella pneumoniae septicemia | |
| A41.59 | Other gram-negative sepsis |
| Klebsiella urinary tract infection | |
| B96.1 | Klebsiella pneumoniae [k. pneumoniae] as the cause of diseases classified elsewhere |
| N30.0 | Acute cystitis |
| N30.00 | Acute cystitis without hematuria |
| N30.01 | Acute cystitis with hematuria |
| N30.9 | Cystitis, unspecified |
| N30.90 | Cystitis, unspecified without hematuria |
| N30.91 | Cystitis, unspecified with hematuria |
| N39.0 | Urinary tract infection, site not specified |
| O23.0 | Infections of kidney in pregnancy |
| O23.00 | Infections of kidney in pregnancy, unspecified trimester |
| O23.01 | Infections of kidney in pregnancy, first trimester |
| O23.02 | Infections of kidney in pregnancy, second trimester |
| O23.03 | Infections of kidney in pregnancy, third trimester |
| O23.1 | Infections of bladder in pregnancy |
| O23.10 | Infections of bladder in pregnancy, unspecified trimester |
| O23.11 | Infections of bladder in pregnancy, first trimester |
| O23.12 | Infections of bladder in pregnancy, second trimester |
| O23.13 | Infections of bladder in pregnancy, third trimester |
| O23.2 | Infections of urethra in pregnancy |
| O23.20 | Infections of urethra in pregnancy, unspecified trimester |
| O23.21 | Infections of urethra in pregnancy, first trimester |
| O23.22 | Infections of urethra in pregnancy, second trimester |
| O23.23 | Infections of urethra in pregnancy, third trimester |
| O23.3 | Infections of other parts of urinary tract in pregnancy |
| O23.30 | Infections of other parts of urinary tract in pregnancy, unspecified trimester |
| O23.31 | Infections of other parts of urinary tract in pregnancy, first trimester |
| O23.32 | Infections of other parts of urinary tract in pregnancy, second trimester |
| O23.33 | Infections of other parts of urinary tract in pregnancy, third trimester |
| O23.4 | Unspecified infection of urinary tract in pregnancy |
| O23.40 | Unspecified infection of urinary tract in pregnancy, unspecified trimester |
| O23.41 | Unspecified infection of urinary tract in pregnancy, first trimester |
| O23.42 | Unspecified infection of urinary tract in pregnancy, second trimester |
| O23.43 | Unspecified infection of urinary tract in pregnancy, third trimester |
| O23.9 | Unspecified genitourinary tract infection in pregnancy |
| O23.90 | Unspecified genitourinary tract infection in pregnancy, unspecified trimester |
| O23.91 | Unspecified genitourinary tract infection in pregnancy, first trimester |
| O23.92 | Unspecified genitourinary tract infection in pregnancy, second trimester |
| O23.93 | Unspecified genitourinary tract infection in pregnancy, third trimester |
| Skin and skin structure e. coli infection | |
| B96.2 | Escherichia coli [e. coli ] as the cause of diseases classified elsewhere |
| B96.20 | Unspecified escherichia coli [e. coli] as the cause of diseases classified elsewhere |
| B96.29 | Other escherichia coli [e. coli] as the cause of diseases classified elsewhere |
| L08.9 | Local infection of the skin and subcutaneous tissue, unspecified |
| Skin and skin structure enterobacter infection | |
| B96.89 | Other specified bacterial agents as the cause of diseases classified elsewhere |
| L03.31A | Cellulitis of flank |
| L03.32A | Acute lymphangitis of flank |
| L08.9 | Local infection of the skin and subcutaneous tissue, unspecified |
| Skin and skin structure infection | |
| H05.01 | Cellulitis of orbit |
| H05.011 | Cellulitis of right orbit |
| H05.012 | Cellulitis of left orbit |
| H05.013 | Cellulitis of bilateral orbits |
| H05.019 | Cellulitis of unspecified orbit |
| H60.1 | Cellulitis of external ear |
| H60.10 | Cellulitis of external ear, unspecified ear |
| H60.11 | Cellulitis of right external ear |
| H60.12 | Cellulitis of left external ear |
| H60.13 | Cellulitis of external ear, bilateral |
| K12.2 | Cellulitis and abscess of mouth |
| L02.217 | Cutaneous abscess of flank |
| L02.227 | Furuncle of flank |
| L03 | Cellulitis and acute lymphangitis |
| L03.0 | Cellulitis and acute lymphangitis of finger and toe |
| L03.01 | Cellulitis of finger |
| L03.011 | Cellulitis of right finger |
| L03.012 | Cellulitis of left finger |
| L03.019 | Cellulitis of unspecified finger |
| L03.03 | Cellulitis of toe |
| L03.031 | Cellulitis of right toe |
| L03.032 | Cellulitis of left toe |
| L03.039 | Cellulitis of unspecified toe |
| L03.1 | Cellulitis and acute lymphangitis of other parts of limb |
| L03.11 | Cellulitis of other parts of limb |
| L03.111 | Cellulitis of right axilla |
| L03.112 | Cellulitis of left axilla |
| L03.113 | Cellulitis of right upper limb |
| L03.114 | Cellulitis of left upper limb |
| L03.115 | Cellulitis of right lower limb |
| L03.116 | Cellulitis of left lower limb |
| L03.119 | Cellulitis of unspecified part of limb |
| L03.2 | Cellulitis and acute lymphangitis of face and neck |
| L03.21 | Cellulitis and acute lymphangitis of face |
| L03.211 | Cellulitis of face |
| L03.22 | Cellulitis and acute lymphangitis of neck |
| L03.221 | Cellulitis of neck |
| L03.3 | Cellulitis and acute lymphangitis of trunk |
| L03.31 | Cellulitis of trunk |
| L03.311 | Cellulitis of abdominal wall |
| L03.312 | Cellulitis of back [any part except buttock] |
| L03.313 | Cellulitis of chest wall |
| L03.314 | Cellulitis of groin |
| L03.315 | Cellulitis of perineum |
| L03.316 | Cellulitis of umbilicus |
| L03.317 | Cellulitis of buttock |
| L03.319 | Cellulitis of trunk, unspecified |
| L03.31A | Cellulitis of flank |
| L03.8 | Cellulitis and acute lymphangitis of other sites |
| L03.81 | Cellulitis of other sites |
| L03.811 | Cellulitis of head [any part, except face] |
| L03.818 | Cellulitis of other sites |
| L03.9 | Cellulitis and acute lymphangitis, unspecified |
| L03.90 | Cellulitis, unspecified |
| L08.9 | Local infection of the skin and subcutaneous tissue, unspecified |
| N48.22 | Cellulitis of corpus cavernosum and penis |
| Skin and skin structure klebsiella infection | |
| B96.1 | Klebsiella pneumoniae [k. pneumoniae] as the cause of diseases classified elsewhere |
| L08.9 | Local infection of the skin and subcutaneous tissue, unspecified |
| Skin and skin structure strep. pyogenes infection | |
| B95.0 | Streptococcus, group a, as the cause of diseases classified elsewhere |
| B95.4 | Other streptococcus as the cause of diseases classified elsewhere |
| L08.89 | Other specified local infections of the skin and subcutaneous tissue |
| L08.9 | Local infection of the skin and subcutaneous tissue, unspecified |
| Staphylococcal meningitis | |
| G00.3 | Staphylococcal meningitis |
| Staphylococcal pneumonia | |
| J15.2 | Pneumonia due to staphylococcus |
| J15.20 | Pneumonia due to staphylococcus, unspecified |
| J15.21 | Pneumonia due to staphylococcus aureus |
| J15.211 | Pneumonia due to methicillin susceptible staphylococcus aureus |
| J15.212 | Pneumonia due to methicillin resistant staphylococcus aureus |
| J15.29 | Pneumonia due to other staphylococcus |
| Staphylococcal septicemia | |
| A41.0 | Sepsis due to staphylococcus aureus |
| A41.01 | Sepsis due to methicillin susceptible staphylococcus aureus |
| A41.02 | Sepsis due to methicillin resistant staphylococcus aureus |
| A41.1 | Sepsis due to other specified staphylococcus |
| A41.2 | Sepsis due to unspecified staphylococcus |
| P36.2 | Sepsis of newborn due to staphylococcus aureus |
| P36.3 | Sepsis of newborn due to other and unspecified staphylococci |
| P36.30 | Sepsis of newborn due to unspecified staphylococci |
| P36.39 | Sepsis of newborn due to other staphylococci |
| Staphylococcus aureus joint infection | |
| M00.0 | Staphylococcal arthritis and polyarthritis |
| M00.00 | Staphylococcal arthritis, unspecified joint |
| M00.01 | Staphylococcal arthritis, shoulder |
| M00.011 | Staphylococcal arthritis, right shoulder |
| M00.012 | Staphylococcal arthritis, left shoulder |
| M00.019 | Staphylococcal arthritis, unspecified shoulder |
| M00.02 | Staphylococcal arthritis, elbow |
| M00.021 | Staphylococcal arthritis, right elbow |
| M00.022 | Staphylococcal arthritis, left elbow |
| M00.029 | Staphylococcal arthritis, unspecified elbow |
| M00.03 | Staphylococcal arthritis, wrist |
| M00.031 | Staphylococcal arthritis, right wrist |
| M00.032 | Staphylococcal arthritis, left wrist |
| M00.039 | Staphylococcal arthritis, unspecified wrist |
| M00.04 | Staphylococcal arthritis, hand |
| M00.041 | Staphylococcal arthritis, right hand |
| M00.042 | Staphylococcal arthritis, left hand |
| M00.049 | Staphylococcal arthritis, unspecified hand |
| M00.05 | Staphylococcal arthritis, hip |
| M00.051 | Staphylococcal arthritis, right hip |
| M00.052 | Staphylococcal arthritis, left hip |
| M00.059 | Staphylococcal arthritis, unspecified hip |
| M00.06 | Staphylococcal arthritis, knee |
| M00.061 | Staphylococcal arthritis, right knee |
| M00.062 | Staphylococcal arthritis, left knee |
| M00.069 | Staphylococcal arthritis, unspecified knee |
| M00.07 | Staphylococcal arthritis, ankle and foot |
| M00.071 | Staphylococcal arthritis, right ankle and foot |
| M00.072 | Staphylococcal arthritis, left ankle and foot |
| M00.079 | Staphylococcal arthritis, unspecified ankle and foot |
| M00.08 | Staphylococcal arthritis, vertebrae |
| M00.09 | Staphylococcal polyarthritis |
| Staphylococcus aureus osteomyelitis | |
| B95.6 | Staphylococcus aureus as the cause of diseases classified elsewhere |
| B95.61 | Methicillin susceptible staphylococcus aureus infection as the cause of diseases classified elsewhere |
| B95.62 | Methicillin resistant staphylococcus aureus infection as the cause of diseases classified elsewhere |
| H05.02 | Osteomyelitis of orbit |
| H05.021 | Osteomyelitis of right orbit |
| H05.022 | Osteomyelitis of left orbit |
| H05.023 | Osteomyelitis of bilateral orbits |
| H05.029 | Osteomyelitis of unspecified orbit |
| M46.2 | Osteomyelitis of vertebra |
| M46.20 | Osteomyelitis of vertebra, site unspecified |
| M46.21 | Osteomyelitis of vertebra, occipito-atlanto-axial region |
| M46.22 | Osteomyelitis of vertebra, cervical region |
| M46.23 | Osteomyelitis of vertebra, cervicothoracic region |
| M46.24 | Osteomyelitis of vertebra, thoracic region |
| M46.25 | Osteomyelitis of vertebra, thoracolumbar region |
| M46.26 | Osteomyelitis of vertebra, lumbar region |
| M46.27 | Osteomyelitis of vertebra, lumbosacral region |
| M46.28 | Osteomyelitis of vertebra, sacral and sacrococcygeal region |
| M86 | Osteomyelitis |
| M86.0 | Acute hematogenous osteomyelitis |
| M86.00 | Acute hematogenous osteomyelitis, unspecified site |
| M86.01 | Acute hematogenous osteomyelitis, shoulder |
| M86.011 | Acute hematogenous osteomyelitis, right shoulder |
| M86.012 | Acute hematogenous osteomyelitis, left shoulder |
| M86.019 | Acute hematogenous osteomyelitis, unspecified shoulder |
| M86.02 | Acute hematogenous osteomyelitis, humerus |
| M86.021 | Acute hematogenous osteomyelitis, right humerus |
| M86.022 | Acute hematogenous osteomyelitis, left humerus |
| M86.029 | Acute hematogenous osteomyelitis, unspecified humerus |
| M86.03 | Acute hematogenous osteomyelitis, radius and ulna |
| M86.031 | Acute hematogenous osteomyelitis, right radius and ulna |
| M86.032 | Acute hematogenous osteomyelitis, left radius and ulna |
| M86.039 | Acute hematogenous osteomyelitis, unspecified radius and ulna |
| M86.04 | Acute hematogenous osteomyelitis, hand |
| M86.041 | Acute hematogenous osteomyelitis, right hand |
| M86.042 | Acute hematogenous osteomyelitis, left hand |
| M86.049 | Acute hematogenous osteomyelitis, unspecified hand |
| M86.05 | Acute hematogenous osteomyelitis, femur |
| M86.051 | Acute hematogenous osteomyelitis, right femur |
| M86.052 | Acute hematogenous osteomyelitis, left femur |
| M86.059 | Acute hematogenous osteomyelitis, unspecified femur |
| M86.06 | Acute hematogenous osteomyelitis, tibia and fibula |
| M86.061 | Acute hematogenous osteomyelitis, right tibia and fibula |
| M86.062 | Acute hematogenous osteomyelitis, left tibia and fibula |
| M86.069 | Acute hematogenous osteomyelitis, unspecified tibia and fibula |
| M86.07 | Acute hematogenous osteomyelitis, ankle and foot |
| M86.071 | Acute hematogenous osteomyelitis, right ankle and foot |
| M86.072 | Acute hematogenous osteomyelitis, left ankle and foot |
| M86.079 | Acute hematogenous osteomyelitis, unspecified ankle and foot |
| M86.08 | Acute hematogenous osteomyelitis, other sites |
| M86.09 | Acute hematogenous osteomyelitis, multiple sites |
| M86.1 | Other acute osteomyelitis |
| M86.10 | Other acute osteomyelitis, unspecified site |
| M86.11 | Other acute osteomyelitis, shoulder |
| M86.111 | Other acute osteomyelitis, right shoulder |
| M86.112 | Other acute osteomyelitis, left shoulder |
| M86.119 | Other acute osteomyelitis, unspecified shoulder |
| M86.12 | Other acute osteomyelitis, humerus |
| M86.121 | Other acute osteomyelitis, right humerus |
| M86.122 | Other acute osteomyelitis, left humerus |
| M86.129 | Other acute osteomyelitis, unspecified humerus |
| M86.13 | Other acute osteomyelitis, radius and ulna |
| M86.131 | Other acute osteomyelitis, right radius and ulna |
| M86.132 | Other acute osteomyelitis, left radius and ulna |
| M86.139 | Other acute osteomyelitis, unspecified radius and ulna |
| M86.14 | Other acute osteomyelitis, hand |
| M86.141 | Other acute osteomyelitis, right hand |
| M86.142 | Other acute osteomyelitis, left hand |
| M86.149 | Other acute osteomyelitis, unspecified hand |
| M86.15 | Other acute osteomyelitis, femur |
| M86.151 | Other acute osteomyelitis, right femur |
| M86.152 | Other acute osteomyelitis, left femur |
| M86.159 | Other acute osteomyelitis, unspecified femur |
| M86.16 | Other acute osteomyelitis, tibia and fibula |
| M86.161 | Other acute osteomyelitis, right tibia and fibula |
| M86.162 | Other acute osteomyelitis, left tibia and fibula |
| M86.169 | Other acute osteomyelitis, unspecified tibia and fibula |
| M86.17 | Other acute osteomyelitis, ankle and foot |
| M86.171 | Other acute osteomyelitis, right ankle and foot |
| M86.172 | Other acute osteomyelitis, left ankle and foot |
| M86.179 | Other acute osteomyelitis, unspecified ankle and foot |
| M86.18 | Other acute osteomyelitis, other site |
| M86.19 | Other acute osteomyelitis, multiple sites |
| M86.2 | Subacute osteomyelitis |
| M86.20 | Subacute osteomyelitis, unspecified site |
| M86.21 | Subacute osteomyelitis, shoulder |
| M86.211 | Subacute osteomyelitis, right shoulder |
| M86.212 | Subacute osteomyelitis, left shoulder |
| M86.219 | Subacute osteomyelitis, unspecified shoulder |
| M86.22 | Subacute osteomyelitis, humerus |
| M86.221 | Subacute osteomyelitis, right humerus |
| M86.222 | Subacute osteomyelitis, left humerus |
| M86.229 | Subacute osteomyelitis, unspecified humerus |
| M86.23 | Subacute osteomyelitis, radius and ulna |
| M86.231 | Subacute osteomyelitis, right radius and ulna |
| M86.232 | Subacute osteomyelitis, left radius and ulna |
| M86.239 | Subacute osteomyelitis, unspecified radius and ulna |
| M86.24 | Subacute osteomyelitis, hand |
| M86.241 | Subacute osteomyelitis, right hand |
| M86.242 | Subacute osteomyelitis, left hand |
| M86.249 | Subacute osteomyelitis, unspecified hand |
| M86.25 | Subacute osteomyelitis, femur |
| M86.251 | Subacute osteomyelitis, right femur |
| M86.252 | Subacute osteomyelitis, left femur |
| M86.259 | Subacute osteomyelitis, unspecified femur |
| M86.26 | Subacute osteomyelitis, tibia and fibula |
| M86.261 | Subacute osteomyelitis, right tibia and fibula |
| M86.262 | Subacute osteomyelitis, left tibia and fibula |
| M86.269 | Subacute osteomyelitis, unspecified tibia and fibula |
| M86.27 | Subacute osteomyelitis, ankle and foot |
| M86.271 | Subacute osteomyelitis, right ankle and foot |
| M86.272 | Subacute osteomyelitis, left ankle and foot |
| M86.279 | Subacute osteomyelitis, unspecified ankle and foot |
| M86.28 | Subacute osteomyelitis, other site |
| M86.29 | Subacute osteomyelitis, multiple sites |
| M86.3 | Chronic multifocal osteomyelitis |
| M86.30 | Chronic multifocal osteomyelitis, unspecified site |
| M86.31 | Chronic multifocal osteomyelitis, shoulder |
| M86.311 | Chronic multifocal osteomyelitis, right shoulder |
| M86.312 | Chronic multifocal osteomyelitis, left shoulder |
| M86.319 | Chronic multifocal osteomyelitis, unspecified shoulder |
| M86.32 | Chronic multifocal osteomyelitis, humerus |
| M86.321 | Chronic multifocal osteomyelitis, right humerus |
| M86.322 | Chronic multifocal osteomyelitis, left humerus |
| M86.329 | Chronic multifocal osteomyelitis, unspecified humerus |
| M86.33 | Chronic multifocal osteomyelitis, radius and ulna |
| M86.331 | Chronic multifocal osteomyelitis, right radius and ulna |
| M86.332 | Chronic multifocal osteomyelitis, left radius and ulna |
| M86.339 | Chronic multifocal osteomyelitis, unspecified radius and ulna |
| M86.34 | Chronic multifocal osteomyelitis, hand |
| M86.341 | Chronic multifocal osteomyelitis, right hand |
| M86.342 | Chronic multifocal osteomyelitis, left hand |
| M86.349 | Chronic multifocal osteomyelitis, unspecified hand |
| M86.35 | Chronic multifocal osteomyelitis, femur |
| M86.351 | Chronic multifocal osteomyelitis, right femur |
| M86.352 | Chronic multifocal osteomyelitis, left femur |
| M86.359 | Chronic multifocal osteomyelitis, unspecified femur |
| M86.36 | Chronic multifocal osteomyelitis, tibia and fibula |
| M86.361 | Chronic multifocal osteomyelitis, right tibia and fibula |
| M86.362 | Chronic multifocal osteomyelitis, left tibia and fibula |
| M86.369 | Chronic multifocal osteomyelitis, unspecified tibia and fibula |
| M86.37 | Chronic multifocal osteomyelitis, ankle and foot |
| M86.371 | Chronic multifocal osteomyelitis, right ankle and foot |
| M86.372 | Chronic multifocal osteomyelitis, left ankle and foot |
| M86.379 | Chronic multifocal osteomyelitis, unspecified ankle and foot |
| M86.38 | Chronic multifocal osteomyelitis, other site |
| M86.39 | Chronic multifocal osteomyelitis, multiple sites |
| M86.4 | Chronic osteomyelitis with draining sinus |
| M86.40 | Chronic osteomyelitis with draining sinus, unspecified site |
| M86.41 | Chronic osteomyelitis with draining sinus, shoulder |
| M86.411 | Chronic osteomyelitis with draining sinus, right shoulder |
| M86.412 | Chronic osteomyelitis with draining sinus, left shoulder |
| M86.419 | Chronic osteomyelitis with draining sinus, unspecified shoulder |
| M86.42 | Chronic osteomyelitis with draining sinus, humerus |
| M86.421 | Chronic osteomyelitis with draining sinus, right humerus |
| M86.422 | Chronic osteomyelitis with draining sinus, left humerus |
| M86.429 | Chronic osteomyelitis with draining sinus, unspecified humerus |
| M86.43 | Chronic osteomyelitis with draining sinus, radius and ulna |
| M86.431 | Chronic osteomyelitis with draining sinus, right radius and ulna |
| M86.432 | Chronic osteomyelitis with draining sinus, left radius and ulna |
| M86.439 | Chronic osteomyelitis with draining sinus, unspecified radius and ulna |
| M86.44 | Chronic osteomyelitis with draining sinus, hand |
| M86.441 | Chronic osteomyelitis with draining sinus, right hand |
| M86.442 | Chronic osteomyelitis with draining sinus, left hand |
| M86.449 | Chronic osteomyelitis with draining sinus, unspecified hand |
| M86.45 | Chronic osteomyelitis with draining sinus, femur |
| M86.451 | Chronic osteomyelitis with draining sinus, right femur |
| M86.452 | Chronic osteomyelitis with draining sinus, left femur |
| M86.459 | Chronic osteomyelitis with draining sinus, unspecified femur |
| M86.46 | Chronic osteomyelitis with draining sinus, tibia and fibula |
| M86.461 | Chronic osteomyelitis with draining sinus, right tibia and fibula |
| M86.462 | Chronic osteomyelitis with draining sinus, left tibia and fibula |
| M86.469 | Chronic osteomyelitis with draining sinus, unspecified tibia and fibula |
| M86.47 | Chronic osteomyelitis with draining sinus, ankle and foot |
| M86.471 | Chronic osteomyelitis with draining sinus, right ankle and foot |
| M86.472 | Chronic osteomyelitis with draining sinus, left ankle and foot |
| M86.479 | Chronic osteomyelitis with draining sinus, unspecified ankle and foot |
| M86.48 | Chronic osteomyelitis with draining sinus, other site |
| M86.49 | Chronic osteomyelitis with draining sinus, multiple sites |
| M86.5 | Other chronic hematogenous osteomyelitis |
| M86.50 | Other chronic hematogenous osteomyelitis, unspecified site |
| M86.51 | Other chronic hematogenous osteomyelitis, shoulder |
| M86.511 | Other chronic hematogenous osteomyelitis, right shoulder |
| M86.512 | Other chronic hematogenous osteomyelitis, left shoulder |
| M86.519 | Other chronic hematogenous osteomyelitis, unspecified shoulder |
| M86.52 | Other chronic hematogenous osteomyelitis, humerus |
| M86.521 | Other chronic hematogenous osteomyelitis, right humerus |
| M86.522 | Other chronic hematogenous osteomyelitis, left humerus |
| M86.529 | Other chronic hematogenous osteomyelitis, unspecified humerus |
| M86.53 | Other chronic hematogenous osteomyelitis, radius and ulna |
| M86.531 | Other chronic hematogenous osteomyelitis, right radius and ulna |
| M86.532 | Other chronic hematogenous osteomyelitis, left radius and ulna |
| M86.539 | Other chronic hematogenous osteomyelitis, unspecified radius and ulna |
| M86.54 | Other chronic hematogenous osteomyelitis, hand |
| M86.541 | Other chronic hematogenous osteomyelitis, right hand |
| M86.542 | Other chronic hematogenous osteomyelitis, left hand |
| M86.549 | Other chronic hematogenous osteomyelitis, unspecified hand |
| M86.55 | Other chronic hematogenous osteomyelitis, femur |
| M86.551 | Other chronic hematogenous osteomyelitis, right femur |
| M86.552 | Other chronic hematogenous osteomyelitis, left femur |
| M86.559 | Other chronic hematogenous osteomyelitis, unspecified femur |
| M86.56 | Other chronic hematogenous osteomyelitis, tibia and fibula |
| M86.561 | Other chronic hematogenous osteomyelitis, right tibia and fibula |
| M86.562 | Other chronic hematogenous osteomyelitis, left tibia and fibula |
| M86.569 | Other chronic hematogenous osteomyelitis, unspecified tibia and fibula |
| M86.57 | Other chronic hematogenous osteomyelitis, ankle and foot |
| M86.571 | Other chronic hematogenous osteomyelitis, right ankle and foot |
| M86.572 | Other chronic hematogenous osteomyelitis, left ankle and foot |
| M86.579 | Other chronic hematogenous osteomyelitis, unspecified ankle and foot |
| M86.58 | Other chronic hematogenous osteomyelitis, other site |
| M86.59 | Other chronic hematogenous osteomyelitis, multiple sites |
| M86.6 | Other chronic osteomyelitis |
| M86.60 | Other chronic osteomyelitis, unspecified site |
| M86.61 | Other chronic osteomyelitis, shoulder |
| M86.611 | Other chronic osteomyelitis, right shoulder |
| M86.612 | Other chronic osteomyelitis, left shoulder |
| M86.619 | Other chronic osteomyelitis, unspecified shoulder |
| M86.62 | Other chronic osteomyelitis, humerus |
| M86.621 | Other chronic osteomyelitis, right humerus |
| M86.622 | Other chronic osteomyelitis, left humerus |
| M86.629 | Other chronic osteomyelitis, unspecified humerus |
| M86.63 | Other chronic osteomyelitis, radius and ulna |
| M86.631 | Other chronic osteomyelitis, right radius and ulna |
| M86.632 | Other chronic osteomyelitis, left radius and ulna |
| M86.639 | Other chronic osteomyelitis, unspecified radius and ulna |
| M86.64 | Other chronic osteomyelitis, hand |
| M86.641 | Other chronic osteomyelitis, right hand |
| M86.642 | Other chronic osteomyelitis, left hand |
| M86.649 | Other chronic osteomyelitis, unspecified hand |
| M86.65 | Other chronic osteomyelitis, thigh |
| M86.651 | Other chronic osteomyelitis, right thigh |
| M86.652 | Other chronic osteomyelitis, left thigh |
| M86.659 | Other chronic osteomyelitis, unspecified thigh |
| M86.66 | Other chronic osteomyelitis, tibia and fibula |
| M86.661 | Other chronic osteomyelitis, right tibia and fibula |
| M86.662 | Other chronic osteomyelitis, left tibia and fibula |
| M86.669 | Other chronic osteomyelitis, unspecified tibia and fibula |
| M86.67 | Other chronic osteomyelitis, ankle and foot |
| M86.671 | Other chronic osteomyelitis, right ankle and foot |
| M86.672 | Other chronic osteomyelitis, left ankle and foot |
| M86.679 | Other chronic osteomyelitis, unspecified ankle and foot |
| M86.68 | Other chronic osteomyelitis, other site |
| M86.69 | Other chronic osteomyelitis, multiple sites |
| M86.8 | Other osteomyelitis |
| M86.8x | Other osteomyelitis |
| M86.8x0 | Other osteomyelitis, multiple sites |
| M86.8x1 | Other osteomyelitis, shoulder |
| M86.8x2 | Other osteomyelitis, upper arm |
| M86.8x3 | Other osteomyelitis, forearm |
| M86.8x4 | Other osteomyelitis, hand |
| M86.8x5 | Other osteomyelitis, thigh |
| M86.8x6 | Other osteomyelitis, lower leg |
| M86.8x7 | Other osteomyelitis, ankle and foot |
| M86.8x8 | Other osteomyelitis, other site |
| M86.8x9 | Other osteomyelitis, unspecified sites |
| M86.9 | Osteomyelitis, unspecified |
| Staphylococcus aureus skin and skin structure infection | |
| B95.6 | Staphylococcus aureus as the cause of diseases classified elsewhere |
| H60.1 | Cellulitis of external ear |
| H60.10 | Cellulitis of external ear, unspecified ear |
| H60.11 | Cellulitis of right external ear |
| H60.12 | Cellulitis of left external ear |
| H60.13 | Cellulitis of external ear, bilateral |
| J34.0 | Abscess, furuncle and carbuncle of nose |
| L02 | Cutaneous abscess, furuncle and carbuncle |
| L02.0 | Cutaneous abscess, furuncle and carbuncle of face |
| L02.02 | Furuncle of face |
| L02.03 | Carbuncle of face |
| L02.1 | Cutaneous abscess, furuncle and carbuncle of neck |
| L02.12 | Furuncle of neck |
| L02.13 | Carbuncle of neck |
| L02.2 | Cutaneous abscess, furuncle and carbuncle of trunk |
| L02.217 | Cutaneous abscess of flank |
| L02.22 | Furuncle of trunk |
| L02.221 | Furuncle of abdominal wall |
| L02.222 | Furuncle of back [any part, except buttock and flank] |
| L02.223 | Furuncle of chest wall |
| L02.224 | Furuncle of groin |
| L02.225 | Furuncle of perineum |
| L02.226 | Furuncle of umbilicus |
| L02.227 | Furuncle of flank |
| L02.229 | Furuncle of trunk, unspecified |
| L02.23 | Carbuncle of trunk |
| L02.231 | Carbuncle of abdominal wall |
| L02.232 | Carbuncle of back [any part, except buttock] |
| L02.233 | Carbuncle of chest wall |
| L02.234 | Carbuncle of groin |
| L02.235 | Carbuncle of perineum |
| L02.236 | Carbuncle of umbilicus |
| L02.239 | Carbuncle of trunk, unspecified |
| L02.3 | Cutaneous abscess, furuncle and carbuncle of buttock |
| L02.32 | Furuncle of buttock |
| L02.33 | Carbuncle of buttock |
| L02.4 | Cutaneous abscess, furuncle and carbuncle of limb |
| L02.42 | Furuncle of limb |
| L02.421 | Furuncle of right axilla |
| L02.422 | Furuncle of left axilla |
| L02.423 | Furuncle of right upper limb |
| L02.424 | Furuncle of left upper limb |
| L02.425 | Furuncle of right lower limb |
| L02.426 | Furuncle of left lower limb |
| L02.429 | Furuncle of limb, unspecified |
| L02.43 | Carbuncle of limb |
| L02.431 | Carbuncle of right axilla |
| L02.432 | Carbuncle of left axilla |
| L02.433 | Carbuncle of right upper limb |
| L02.434 | Carbuncle of left upper limb |
| L02.435 | Carbuncle of right lower limb |
| L02.436 | Carbuncle of left lower limb |
| L02.439 | Carbuncle of limb, unspecified |
| L02.5 | Cutaneous abscess, furuncle and carbuncle of hand |
| L02.52 | Furuncle hand |
| L02.521 | Furuncle right hand |
| L02.522 | Furuncle left hand |
| L02.529 | Furuncle unspecified hand |
| L02.53 | Carbuncle of hand |
| L02.531 | Carbuncle of right hand |
| L02.532 | Carbuncle of left hand |
| L02.539 | Carbuncle of unspecified hand |
| L02.6 | Cutaneous abscess, furuncle and carbuncle of foot |
| L02.62 | Furuncle of foot |
| L02.621 | Furuncle of right foot |
| L02.622 | Furuncle of left foot |
| L02.629 | Furuncle of unspecified foot |
| L02.63 | Carbuncle of foot |
| L02.631 | Carbuncle of right foot |
| L02.632 | Carbuncle of left foot |
| L02.639 | Carbuncle of unspecified foot |
| L02.8 | Cutaneous abscess, furuncle and carbuncle of other sites |
| L02.82 | Furuncle of other sites |
| L02.821 | Furuncle of head [any part, except face] |
| L02.828 | Furuncle of other sites |
| L02.83 | Carbuncle of other sites |
| L02.831 | Carbuncle of head [any part, except face] |
| L02.838 | Carbuncle of other sites |
| L02.9 | Cutaneous abscess, furuncle and carbuncle, unspecified |
| L02.92 | Furuncle, unspecified |
| L02.93 | Carbuncle, unspecified |
| L03.01 | Cellulitis of finger |
| L03.011 | Cellulitis of right finger |
| L03.012 | Cellulitis of left finger |
| L03.019 | Cellulitis of unspecified finger |
| L03.03 | Cellulitis of toe |
| L03.031 | Cellulitis of right toe |
| L03.032 | Cellulitis of left toe |
| L03.039 | Cellulitis of unspecified toe |
| L03.1 | Cellulitis and acute lymphangitis of other parts of limb |
| L03.11 | Cellulitis of other parts of limb |
| L03.111 | Cellulitis of right axilla |
| L03.112 | Cellulitis of left axilla |
| L03.113 | Cellulitis of right upper limb |
| L03.114 | Cellulitis of left upper limb |
| L03.115 | Cellulitis of right lower limb |
| L03.116 | Cellulitis of left lower limb |
| L03.119 | Cellulitis of unspecified part of limb |
| L03.2 | Cellulitis and acute lymphangitis of face and neck |
| L03.21 | Cellulitis and acute lymphangitis of face |
| L03.211 | Cellulitis of face |
| L03.22 | Cellulitis and acute lymphangitis of neck |
| L03.221 | Cellulitis of neck |
| L03.3 | Cellulitis and acute lymphangitis of trunk |
| L03.31 | Cellulitis of trunk |
| L03.311 | Cellulitis of abdominal wall |
| L03.312 | Cellulitis of back [any part except buttock] |
| L03.313 | Cellulitis of chest wall |
| L03.314 | Cellulitis of groin |
| L03.315 | Cellulitis of perineum |
| L03.316 | Cellulitis of umbilicus |
| L03.317 | Cellulitis of buttock |
| L03.319 | Cellulitis of trunk, unspecified |
| L03.31A | Cellulitis of flank |
| L03.32A | Acute lymphangitis of flank |
| L03.8 | Cellulitis and acute lymphangitis of other sites |
| L03.81 | Cellulitis of other sites |
| L03.811 | Cellulitis of head [any part, except face] |
| L03.818 | Cellulitis of other sites |
| L03.9 | Cellulitis and acute lymphangitis, unspecified |
| L03.90 | Cellulitis, unspecified |
| L08.89 | Other specified local infections of the skin and subcutaneous tissue |
| L08.9 | Local infection of the skin and subcutaneous tissue, unspecified |
| N48.22 | Cellulitis of corpus cavernosum and penis |
| Streptococcal meningitis | |
| G00.1 | Pneumococcal meningitis |
| G00.2 | Streptococcal meningitis |
| Streptococcal pneumonia | |
| J13 | Pneumonia due to streptococcus pneumoniae |
| J15.3 | Pneumonia due to streptococcus, group B |
| J15.4 | Pneumonia due to other streptococci |
| Streptococcal septicemia | |
| A40 | Streptococcal sepsis |
| A40.0 | Sepsis due to streptococcus, group A |
| A40.1 | Sepsis due to streptococcus, group B |
| A40.3 | Sepsis due to streptococcus pneumoniae |
| A40.8 | Other streptococcal sepsis |
| A40.9 | Streptococcal sepsis, unspecified |
| P36.0 | Sepsis of newborn due to streptococcus, group B |
| P36.1 | Sepsis of newborn due to other and unspecified streptococci |
| P36.10 | Sepsis of newborn due to unspecified streptococci |
| P36.19 | Sepsis of newborn due to other streptococci |
Formulary Reference Tool