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DYRENIUM (TRIAMTERENE)
- Edema
- Peripheral edema due to chronic heart failure
- Pulmonary edema due to chronic heart failure
100 mg capsule
- 1 capsule (100 mg) by oral route once daily after a meal
50 mg capsule
- 1 capsule (50 mg) by oral route once daily after a meal
100 mg capsule
- 1 capsule (100 mg) by oral route once daily after a meal
50 mg capsule
- 1 capsule (50 mg) by oral route once daily after a meal
Edema
- 1 capsule (50 mg) by oral route once daily after a meal
- 1 capsule (50 mg) by oral route 2 times per day after meals
- 2 capsules (100 mg) by oral route once daily after a meal
- 2 capsules (100 mg) by oral route 2 times per day after meals
- 1 capsule (100 mg) by oral route 2 times per day after meals
- 1 capsule (100 mg) by oral route once daily after a meal
Hypertension
- 1 capsule (50 mg) by oral route once daily
- 1 capsule (100 mg) by oral route once daily
- 2 capsules (100 mg) by oral route once daily
Peripheral edema due to chronic heart failure
- 1 capsule (50 mg) by oral route once daily after a meal
- 1 capsule (50 mg) by oral route 2 times per day after meals
- 2 capsules (100 mg) by oral route once daily after a meal
- 2 capsules (100 mg) by oral route 2 times per day after meals
- 1 capsule (100 mg) by oral route 2 times per day after meals
- 1 capsule (100 mg) by oral route once daily after a meal
- Astagraf Xl
- cyclosporine
- cyclosporine modified
- Gengraf
- Hecoria
- Neoral
- Prograf
- Sandimmune
- tacrolimus
Contraindicated
- Alka-seltzer Gold
- Ceralyte-70
- Ceraors 75
- Cerasport
- Cerasport Ex1
- Curad Enema
- Cytra K Crystals
- Cytra-3
- Cytra-k
- Disposable Enema
- DM-GG-potassium citrate
- Effer-k
- Enema
- Enema Disposable
- eplerenone
- Fleet Enema
- Fleet Enema Extra
- Fleet Pediatric
- Hyperlyte Cr
- Inspra
- K-effervescent
- K-tab
- Kaochlor
- Klor-con
- Klor-con 10
- Klor-con M10
- Klor-con M15
- Klor-con M20
- Klor-con/ef
- Medi-lyte
- Nano Vm T/f
- Nutrilyte Ii
- Oral Saline Laxative
- Osmoprep
- Pedialyte
- Pediatric Electrolyte
- pediatric multivit #18-iron-FA
- PEG 3350-bowel 2,two part prep
- Phosphate Laxative
- pot & sod citrate-citric acid
- potassium
- potassium bicarb & chloride
- potassium bicarb-citric acid
- potassium chlorid-D5-0.45%NaCl
- potassium chloride
- potassium chloride in 0.9%NaCl
- potassium chloride in D5W
- potassium chloride in LR-D5
- potassium chloride-0.45 % NaCl
- potassium chloride-D5-0.2%NaCl
- potassium chloride-D5-0.3%NaCl
- potassium chloride-D5-0.9%NaCl
- potassium citrate
- potassium citrate-citric acid
- potassium Cl-calcium phos-mag
- potassium gluconate
- potassium phosphate dibasic
- Preparation Cleansing
- Ready-to-use Enema
- Reclast
- sod & pot chlorid-sod cit-rice
- sod phos mono-sod phos dibasic
- sodium & potassium bicarbonate
- sodium Cl-potassium chloride
- sodium phosphates
- sodium-K+-mag-Ca-chlor-acetate
- sodium-potas-chloride-dextrose
- Sorbutuss
- Suclear
- Taron-crystals
- Theralith Xr
- Thermotabs
- Tpn Electrolytes
- Tpn Electrolytes Ii
- Tricitrates
- Urocit-k 10
- Urocit-k 15
- Urocit-k 5
- vit B6-mag cit & ox-potass cit
- zoledronic acid
- zoledronic acid-mannitol-water
- Zometa
Severe
Moderate
- Accupril
- Accuretic
- Aceon
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- Altace
- amlodipine-benazepril
- amlodipine-olmesartan
- amlodipine-valsartan
- amlodipine-valsartan-hcthiazid
- Anaprox
- Anaprox Ds
- Angeliq
- Ansaid
- Arthrotec 50
- Atacand
- Atacand Hct
- Avalide
- Avapro
- azilsartan med-chlorthalidone
- azilsartan medoxomil
- Azor
- benazepril
- benazepril-hydrochlorothiazide
- Benicar
- Benicar Hct
- Beyaz
- Caldolor
- Cambia
- candesartan
- candesartan-hydrochlorothiazid
- captopril
- captopril-hydrochlorothiazide
- Cataflam
- Celebrex
- celecoxib
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- Cozaar
- Daypro
- diclofenac epolamine
- diclofenac potassium
- diclofenac sodium
- diclofenac submicronized
- diclofenac-misoprostol
- Diovan Hct
- drospirenone-e.estradiol-lm.FA
- drospirenone-estradiol
- drospirenone-ethinyl estradiol
- Duexis
- Ec-naprosyn
- Edarbi
- Edarbyclor
- enalapril maleate
- enalapril-hydrochlorothiazide
- enalaprilat
- Epaned
- eprosartan
- eprosartan-hydrochlorothiazide
- etodolac
- Exforge
- Exforge Hct
- Feldene
- fenoprofen
- Flanax
- Flector
- flurbiprofen
- fosinopril
- fosinopril-hydrochlorothiazide
- Gianvi (28)
- hydrocodone-ibuprofen
- Hyzaar
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Indocin
- indomethacin
- indomethacin sodium
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- irbesartan
- irbesartan-hydrochlorothiazide
- ketoprofen
- ketorolac
- lisinopril
- lisinopril-hydrochlorothiazide
- Loryna (28)
- losartan
- losartan-hydrochlorothiazide
- Lotensin
- Lotrel
- Mavik
- Medi-profen
- Mediproxen
- mefenamic acid
- meloxicam
- Micardis
- Micardis Hct
- Midol (naproxen)
- Mobic
- moexipril
- moexipril-hydrochlorothiazide
- Motrin Ib
- Motrin Pm
- nabumetone
- Nalfon
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- Neoprofen (ibuprofen Lysn)(pf)
- Ocella
- olmesartan
- olmesartan-amlodipin-hcthiazid
- olmesartan-hydrochlorothiazide
- oxaprozin
- Pennsaid
- perindopril erbumine
- piroxicam
- Ponstel
- Prinivil
- Provil
- pseudoephedrine-ibuprofen
- quinapril
- quinapril-hydrochlorothiazide
- ramipril
- Reprexain
- Safyral
- Sinus & Cold-d
- Solaraze
- Sprix
- sulindac
- Syeda
- Tarka
- telmisartan
- telmisartan-amlodipine
- telmisartan-hydrochlorothiazid
- Teveten
- Teveten Hct
- tolmetin
- trandolapril
- trandolapril-verapamil
- Tribenzor
- Twynsta
- Uniretic
- Univasc
- valsartan-hydrochlorothiazide
- Vaseretic
- Vasotec
- Vestura (28)
- Vicoprofen
- Vimovo
- Voltaren-xr
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- Yasmin (28)
- Yaz 28
- Zarah
- Zestoretic
- Zestril
- Zipsor
- Zorvolex
- Anuria
- Hyperkalemia
- Pregnancy
- Severe hepatic disease
- Severe renal impairment
Contraindicated
- Acidosis
- Hyponatremia
- Kidney disease with reduction in GFR
- Kidney stone
Severe
Moderate
- Disease of liver
- Folic acid deficient megaloblastic anemia
- Hyperuricemia
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
DYRENIUM (TRIAMTERENE)
- Edema
- Peripheral edema due to chronic heart failure
- Pulmonary edema due to chronic heart failure
- None
- None
More Frequent
Severe
Less Severe
- Hyperkalemia
- Dizziness
- Headache disorder
- Hyponatremia
- Skin photosensitivity
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute renal failure
- Anaphylaxis
- Hypersensitivity drug reaction
- Interstitial nephritis
- Jaundice
- Kidney stone
- Megaloblastic anemia
- Metabolic acidosis
- Skin rash
- Thrombocytopenic disorder
Less Severe
- Diarrhea
- Fatigue
- General weakness
- Hyperuricemia
- Nausea and vomiting
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Triamterene
- Severity Level:
1
- Additional Notes: Fda category c. quadruples risk of cardiovascular defects and oral cleft.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Triamterene
Insufficient human data available; excreted in animal studies
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available; excreted in animal studies |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Triamterene
Renal-Increased risk for hyperkalemia and hyponatremia in patients with severe renal impairment due to potassium sparing effects. May increase risk of kidney injury Stages IV and V CKD. Avoid with CrCl <30 mL/min.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | N | N | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- This medication can increase your potassium levels, especially if you have kidney disease or diabetes, or are severely ill. Potassium levels must be done while you are taking this medication. If not treated, very high potassium levels can sometimes be fatal. If you notice any of the following serious side effects, tell your doctor right away: muscle weakness, slow/irregular heartbeat.
| Edema | |
| R60 | Edema, not elsewhere classified |
| R60.0 | Localized edema |
| R60.1 | Generalized edema |
| R60.9 | Edema, unspecified |
| Peripheral edema due to chronic heart failure | |
| R60 | Edema, not elsewhere classified |
| R60.9 | Edema, unspecified |
| Pulmonary edema due to chronic heart failure | |
| J81.0 | Acute pulmonary edema |
| 0-9 | A-Z |
|---|---|
| J81.0 | Acute pulmonary edema |
| R60 | Edema, not elsewhere classified |
| R60 | Edema, not elsewhere classified |
| R60.0 | Localized edema |
| R60.1 | Generalized edema |
| R60.9 | Edema, unspecified |
| R60.9 | Edema, unspecified |
Formulary Reference Tool