ISRADIPINE (ISRADIPINE)
- Hypertension
2.5 mg capsule
- 1 capsule (2.5 mg) by oral route 2 times per day
5 mg capsule
- 1 capsule (5 mg) by oral route 2 times per day
Hypertension
- 2 capsules (5 mg) by oral route 2 times per day
- 1 capsule (5 mg) by oral route 2 times per day
- 2 capsules (10 mg) by oral route 2 times per day
- 1 capsule (2.5 mg) by oral route 2 times per day
- amiodarone
- amiodarone in dextrose,iso-osm
- artemether-lumefantrine
- Coartem
- Cordarone
- disopyramide
- dronedarone
- droperidol
- Multaq
- Nexterone
- Norpace
- Norpace Cr
- Orap
- Pacerone
- pimozide
Contraindicated
- amoxicil-clarithromy-lansopraz
- Avelox
- Avelox Abc Pack
- Avelox In Nacl (iso-osmotic)
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- Caprelsa
- clarithromycin
- Dantrium
- dantrolene
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- Fareston
- Geodon
- Invega
- Invega Sustenna
- Invirase
- Kaletra
- Ketek
- lopinavir-ritonavir
- moxifloxacin
- moxifloxacin in NaCl (iso-osm)
- nilotinib
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- paliperidone
- paliperidone palmitate
- Prevpac
- propafenone
- Qualaquin
- quetiapine
- quinine sulfate
- Revonto
- Rythmol
- saquinavir mesylate
- Seroquel
- Seroquel Xr
- Tasigna
- telithromycin
- tetrabenazine
- thioridazine
- toremifene
- vandetanib
- Xenazine
- ziprasidone HCl
- ziprasidone mesylate
Severe
Moderate
- Ablavar
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- alfuzosin
- Anzemet
- Apokyn
- apomorphine
- arsenic trioxide
- bedaquiline
- Betapace
- Betapace Af
- cimetidine
- Cipro
- Cipro In D5W
- Cipro Xr
- ciprofloxacin
- ciprofloxacin (mixture)
- ciprofloxacin in D5W
- clozapine
- Clozaril
- Complera
- crizotinib
- dasatinib
- Diskets
- dofetilide
- dolasetron
- Dolophine
- Edurant
- emtricitab-rilpivirine-tenofov
- eribulin
- escitalopram oxalate
- ezogabine
- Fazaclo
- gadofosveset trisodium
- Halaven
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- Heartburn Relief
- isoniazid-rifamp-pyrazinamide
- Istodax
- lapatinib
- Levaquin
- Levaquin In 5 % Dextrose
- levofloxacin
- levofloxacin in D5W
- Lexapro
- methadone
- Methadone Intensol
- Methadose
- Mycobutin
- Nexavar
- norfloxacin
- Noroxin
- Noxafil
- ondansetron
- ondansetron HCl
- ondansetron HCl (PF)
- pasireotide
- pazopanib
- posaconazole
- Potiga
- Priftin
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- rifapentine
- Rifater
- rilpivirine
- romidepsin
- Signifor
- Sirturo
- sorafenib
- Sorine
- sotalol
- Sotalol Af
- Sprycel
- Tagamet Hb
- telavancin
- Tikosyn
- Trisenox
- Tykerb
- Uroxatral
- vemurafenib
- Versacloz
- Vibativ
- Votrient
- Xalkori
- Zelboraf
- Zofran
- Zofran Odt
- Zuplenz
- None
Contraindicated
- Hypotension
- Severe coronary artery disease
Severe
Moderate
- Acute myocardial infarction
- Chronic heart failure
- Disease of liver
- Peripheral edema
ISRADIPINE (ISRADIPINE)
- Hypertension
- None
- Headache disorder
More Frequent
Severe
Less Severe
- Allergic dermatitis
- Angina
- Palpitations
- Peripheral edema
- Skin rash
- Tachycardia
- Diarrhea
- Dizziness
- Fatigue
- Flushing
- Nausea
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Chronic heart failure
- Dyspnea
- Prolonged QT interval
- Pulmonary edema
- Severe hypotension
Less Severe
- Abdominal pain with cramps
- Constipation
- General weakness
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Isradipine
Limited study data available. No safety and efficacy established.
- 1 Day – 18 Years
- Limited study data available. No safety and efficacy established.
Isradipine
- Severity Level:
C
- Additional Notes:
Contraindicated
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Precaution Exists
Isradipine
Insufficient data available.
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available. |
No Known Risk
None
General | Excretion Potential | Effect on Infant | Notes |
None |
Contraindicated
None
Precaution Exists
Isradipine
Cardiovascular-Elderly are more sensitive to blood pressure lowering effects and may have lower drug clearance. Start at lower doses and titrate upward more slowly. Peripheral edema may be common. Gastrointestinal-may cause or worsen pre-existing constipation.
Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- None
Hypertension | |
I10 | Essential (primary) hypertension |
I11 | Hypertensive heart disease |
I11.0 | Hypertensive heart disease with heart failure |
I11.9 | Hypertensive heart disease without heart failure |
I12 | Hypertensive chronic kidney disease |
I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13 | Hypertensive heart and chronic kidney disease |
I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
I15.1 | Hypertension secondary to other renal disorders |
0-9 | A-Z |
---|---|
I10 | Essential (primary) hypertension |
I11 | Hypertensive heart disease |
I11.0 | Hypertensive heart disease with heart failure |
I11.9 | Hypertensive heart disease without heart failure |
I12 | Hypertensive chronic kidney disease |
I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13 | Hypertensive heart and chronic kidney disease |
I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
I15.1 | Hypertension secondary to other renal disorders |