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FENTANYL (FENTANYL)
- Chronic pain with opioid tolerance
- Severe pain with opioid tolerance
100 mcg/hr transdermal patch
- Apply 1 patch (100 mcg/hour) to intact skin by transdermal route every 72 hours
12 mcg/hr transdermal patch
- Apply 1 patch (12 mcg/hour) to intact skin by transdermal route every72 hours
25 mcg/hr transdermal patch
- Apply 1 patch (25 mcg/hour) to intact skin by transdermal route every72 hours
37.5 mcg/hour transdermal patch
- Apply 2 patches (75 mcg/hour) to intact skin by transdermal route every 72 hours
50 mcg/hr transdermal patch
- Apply 1 patch (50 mcg/hour) to intact skin by transdermal route every72 hours
62.5 mcg/hour transdermal patch
- Apply 1 patch (62.5 mcg/hour) to intact skin by transdermal route every 72 hours
75 mcg/hr transdermal patch
- Apply 1 patch (75 mcg/hour) to intact skin by transdermal route every72 hours
87.5 mcg/hour transdermal patch
- Apply 1 patch (87.5 mcg/hour) to intact skin by transdermal route every 72 hours
100 mcg/hr transdermal patch
- Apply 1 patch (100 mcg/hour) to intact skin by transdermal route every 72 hours
12 mcg/hr transdermal patch
- Apply 1 patch (12 mcg/hour) to intact skin by transdermal route every72 hours
25 mcg/hr transdermal patch
- Apply 1 patch (25 mcg/hour) to intact skin by transdermal route every72 hours
37.5 mcg/hour transdermal patch
- Apply 2 patches (75 mcg/hour) to intact skin by transdermal route every 72 hours
50 mcg/hr transdermal patch
- Apply 1 patch (50 mcg/hour) to intact skin by transdermal route every72 hours
62.5 mcg/hour transdermal patch
- Apply 1 patch (62.5 mcg/hour) to intact skin by transdermal route every 72 hours
75 mcg/hr transdermal patch
- Apply 1 patch (75 mcg/hour) to intact skin by transdermal route every72 hours
87.5 mcg/hour transdermal patch
- Apply 1 patch (87.5 mcg/hour) to intact skin by transdermal route every 72 hours
100 mcg/hr transdermal patch
- Apply 1 patch (100 mcg/hour) to intact skin by transdermal route every 72 hours
12 mcg/hr transdermal patch
- Apply 1 patch (12 mcg/hour) to intact skin by transdermal route every72 hours
25 mcg/hr transdermal patch
- Apply 1 patch (25 mcg/hour) to intact skin by transdermal route every72 hours
50 mcg/hr transdermal patch
- Apply 1 patch (50 mcg/hour) to intact skin by transdermal route every72 hours
75 mcg/hr transdermal patch
- Apply 1 patch (75 mcg/hour) to intact skin by transdermal route every72 hours
Chronic pain with opioid tolerance
- Apply 1 patch (12 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (12 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (12 mcg/hour) to intact skin by transdermal route every72 hours
- Apply 1 patch (12 mcg/hour) to intact skin by transdermal route every48 hours
- Apply 2 patches (24 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (24 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (24 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (24 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (25 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (25 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (25 mcg/hour) to intact skin by transdermal route every48 hours
- Apply 1 patch (25 mcg/hour) to intact skin by transdermal route every72 hours
- Apply 3 patches (36 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (36 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (36 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (36 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (50 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 1 patch (50 mcg/hour) to intact skin by transdermal route every72 hours
- Apply 2 patches (50 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (50 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (50 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (50 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (50 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (50 mcg/hour) to intact skin by transdermal route every48 hours
- Apply 3 patches (75 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (75 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (75 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (75 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (75 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (75 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (75 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (75 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (75 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (75 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (75 mcg/hour) to intact skin by transdermal route every48 hours
- Apply 1 patch (75 mcg/hour) to intact skin by transdermal route every72 hours
- Apply 2 patches (100 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (100 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (100 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (100 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (100 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (100 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (100 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 1 patch (100 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (112.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (112.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (112.5 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (112.5 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (125 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (125 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (125 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (125 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (150 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (150 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (150 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (150 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (150 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (150 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (150 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (150 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (175 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (175 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (175 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (175 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (187.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (187.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (187.5 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (187.5 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (200 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (200 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (200 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (200 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (225 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (225 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (225 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (225 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (262.5 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (262.5 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (262.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (262.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (300 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (300 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (300 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (300 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (37.5 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (37.5 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (37.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (37.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 1 patch (62.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 1 patch (62.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (62.5 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (62.5 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (87.5 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (87.5 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (87.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (87.5 mcg/hour) to intact skin by transdermal route every 48 hours
Severe pain with opioid tolerance
- Apply 1 patch (12 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (12 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (12 mcg/hour) to intact skin by transdermal route every72 hours
- Apply 1 patch (12 mcg/hour) to intact skin by transdermal route every48 hours
- Apply 2 patches (24 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (24 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (24 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (24 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (25 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (25 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (25 mcg/hour) to intact skin by transdermal route every48 hours
- Apply 1 patch (25 mcg/hour) to intact skin by transdermal route every72 hours
- Apply 3 patches (36 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (36 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (36 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (36 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (50 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 1 patch (50 mcg/hour) to intact skin by transdermal route every72 hours
- Apply 2 patches (50 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (50 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (50 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (50 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (50 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (50 mcg/hour) to intact skin by transdermal route every48 hours
- Apply 3 patches (75 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (75 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (75 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (75 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (75 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (75 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (75 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (75 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (75 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (75 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (75 mcg/hour) to intact skin by transdermal route every48 hours
- Apply 1 patch (75 mcg/hour) to intact skin by transdermal route every72 hours
- Apply 2 patches (100 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (100 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (100 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (100 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (100 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (100 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (100 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 1 patch (100 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (112.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (112.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (112.5 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (112.5 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (125 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (125 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (125 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (125 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (150 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (150 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (150 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (150 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (150 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (150 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (150 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (150 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (175 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (175 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (175 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 2 patches (175 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (187.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (187.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (187.5 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (187.5 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (200 mcg/hour) by transdermal route every 48 hours
- Apply 2 patches (200 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 2 patches (200 mcg/hour) by transdermal route every 72 hours
- Apply 2 patches (200 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (225 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (225 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (225 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (225 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (262.5 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (262.5 mcg/hour) by transdermal route every 72 hours
- Apply 3 patches (262.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (262.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (300 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 3 patches (300 mcg/hour) by transdermal route every 48 hours
- Apply 3 patches (300 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 3 patches (300 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (37.5 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (37.5 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (37.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (37.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 1 patch (62.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Apply 1 patch (62.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (62.5 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (62.5 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (87.5 mcg/hour) by transdermal route every 72 hours
- Apply 1 patch (87.5 mcg/hour) by transdermal route every 48 hours
- Apply 1 patch (87.5 mcg/hour) to intact skin by transdermal route every 72 hours
- Apply 1 patch (87.5 mcg/hour) to intact skin by transdermal route every 48 hours
- Azilect
- Depade
- Eldepryl
- isocarboxazid
- linezolid
- Marplan
- Matulane
- methylene blue (antidote)
- naltrexone
- naltrexone microspheres
- Nardil
- Parnate
- phenelzine
- procarbazine
- rasagiline
- Revia
- selegiline HCl
- tranylcypromine
- Vivitrol
- Zelapar
- Zyvox
Contraindicated
- amiodarone
- amiodarone in dextrose,iso-osm
- amoxicil-clarithromy-lansopraz
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- boceprevir
- Buprenex
- buprenorphine
- buprenorphine-naloxone
- butorphanol tartrate
- Butrans
- clarithromycin
- conivaptan in 5 % dextrose
- Cordarone
- Crixivan
- Diflucan
- elvitegr-cobicist-emtric-tenof
- enzalutamide
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- fluconazole
- fluconazole in dextrose(iso-o)
- fluconazole in NaCl (iso-osm)
- Incivek
- indinavir
- Invirase
- itraconazole
- Kaletra
- Ketek
- ketoconazole
- lopinavir-ritonavir
- nalbuphine
- nefazodone
- nelfinavir
- Nexterone
- Norvir
- Norvir Soft Gelatin
- Noxafil
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Onmel
- Pacerone
- posaconazole
- Prevpac
- ritonavir
- saquinavir mesylate
- sodium oxybate
- Sporanox
- Sporanox Pulsepak
- Stribild
- Suboxone
- telaprevir
- telithromycin
- Vaprisol
- Vfend
- Vfend Iv
- Victrelis
- Viracept
- voriconazole
- Xtandi
- Xyrem
- Zubsolv
Severe
Moderate
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- Anafranil
- aprepitant
- atazanavir
- Brintellix
- Brisdelle
- Calan
- Calan Sr
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- Celexa
- cimetidine
- Cipro
- Cipro In D5W
- Cipro Xr
- ciprofloxacin
- ciprofloxacin (mixture)
- ciprofloxacin in D5W
- citalopram
- clomipramine
- Cymbalta
- darunavir
- desvenlafaxine
- desvenlafaxine fumarate
- desvenlafaxine succinate
- Dilacor Xr
- Dilt-xr
- diltiazem HCl
- Diprivan
- dronedarone
- duloxetine
- Effexor Xr
- Emend
- escitalopram oxalate
- Fanatrex
- Fetzima
- fluoxetine
- fluvoxamine
- fosamprenavir
- fosaprepitant
- gabapentin
- gabapentin enacarbil
- Gleevec
- Gralise
- Gralise 30-day Starter Pack
- Heartburn Relief
- Horizant
- imatinib
- isoniazid-rifamp-pyrazinamide
- Khedezla
- levomilnacipran
- Lexapro
- Lexiva
- Luvox Cr
- Matzim La
- milnacipran
- Multaq
- Neurontin
- olanzapine-fluoxetine
- paroxetine HCl
- paroxetine mesylate
- Paxil
- Paxil Cr
- Pexeva
- Prezista
- Pristiq
- propofol
- Prozac
- Prozac Weekly
- Reyataz
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- Sarafem
- Savella
- sertraline
- Symbyax
- Tagamet Hb
- Tarka
- Taztia Xt
- Tiazac
- trandolapril-verapamil
- venlafaxine
- verapamil
- Verelan
- Verelan Pm
- Viibryd
- vilazodone
- vortioxetine
- Zoloft
- Acute asthma attack
- Acute postoperative pain without opiate tolerance
- Paralytic ileus
Contraindicated
- Acute pancreatitis
- Alcohol intoxication
- Coma
- Drug abuse
- Fever
- History of opioid overdose
- Hypotension
- Inflammatory bowel disease
- Intracranial hypertension
- Kidney disease with reduction in GFR
- Magnetic resonance imaging
- Respiratory depression
- Severe hepatic disease
Severe
Moderate
- Adrenal cortical insufficiency
- Biliary tract disorder
- Bradycardia
- Cachexia
- Chronic obstructive pulmonary disease
- Constipation
- Cor pulmonale
- Debilitation
- Urinary retention
FENTANYL (FENTANYL)
- Chronic pain with opioid tolerance
- Severe pain with opioid tolerance
- Apnea
- CNS depression
- Dyspnea
- Fever
- Hallucinations
- Urinary retention
- Acute confusion
- Anorexia
- Constipation
- Diarrhea
- Dizziness
- Drowsy
- False sense of well-being
- Gastric acid hypersecretory conditions
- General weakness
- Headache disorder
- Hyperhidrosis
- Insomnia
- Nausea
- Nervousness
- Pruritus of skin
- Sensation of cold
- Symptoms of anxiety
- Vomiting
- Xerostomia
More Frequent
Severe
Less Severe
- Cardiac arrhythmia
- Chest pain
- Depression
- Dyskinesia
- Hemoptysis
- Hypotension
- Paranoid disorder
- Respiratory depression
- Slurred speech
- Syncope
- Unsteady gait
- Upper respiratory infection
- Agitation
- Fatigue
- Flu-like symptoms
- Memory impairment
- Nightmares
- Pharyngitis
- Sedation
- Stinging of skin
- Treatment site sequelae
- Upper abdominal pain
- Vertigo
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abdominal distension
- Amblyopia
- Asthma
- Blistering skin
- Bradycardia
- Chest tightness
- CNS toxicity
- Disorder of adrenal gland
- Exfoliative dermatitis
- Hypertension
- Oliguria
- Respiration changes
- Serotonin syndrome
- Urinary urgency
- Wheezing
Less Severe
- Bladder pain
- Blurred vision
- Erectile dysfunction
- Hyperesthesia
- Infertility
- Libido changes
- Palpitations
- Tachycardia
Contraindicated
Fentanyl (Patch)
Safety not established age < 2 years. Risk of fatal respiratory depression in opioid-naive.
- 1 Day – 2 Years
- 1 Safety not established age < 2 years. Risk of fatal respiratory depression in opioid-naive.
Severe Precaution
Fentanyl (Patch)
Administration restricted to opioid tolerant patients. Risk of severe respiratory depression.
- 2 Years – 18 Years
- Administration restricted to opioid tolerant patients. Risk of severe respiratory depression.
Management or Monitoring Precaution
None
Fentanyl
- Severity Level:
2
- Additional Notes: Neonatal withdrawal/resp.depress. w/chronic or high dose
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Fentanyl
Insufficient data avail; low levels excreted with short term use
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Insufficient data avail; low levels excreted with short term use |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Fentanyl (patch)
Pulmonary-DO NOT USE in opioid intolerance. Life threatening respiratory depression risk due to altered pharmacokinetics (poor fat stores, muscle wasting, or altered clearance). Monitor closely at initiation and dose titration. Consider naloxone Rx. Neuro/Psych-Risk for confusion, delirium and falls. Avoid treatment with 3 or more CNS active agents. Gastrointestinal-Increased rate of constipation in the elderly. Cardiovascular-Vasodilation may predispose to orthostatic hypotension.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | N | Y | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- Fentanyl has a risk for abuse and addiction, which can lead to overdose and death. Fentanyl may also cause severe, possibly fatal, breathing problems. Do not use transdermal patches unless you have been regularly using moderate to large amounts of opioid pain medication.<br /><br />Otherwise, it may cause overdose (even death). To lower your risk, your doctor should have you use the smallest dose of fentanyl that works, and use it for the shortest possible time. See also How to Use section for more information about addiction.<br /><br /> The risk for severe breathing problems is higher when you start this medication and after a dose increase, or if you use the wrong dose/strength. Using this medication with alcohol or other drugs that can cause drowsiness or breathing problems may cause very serious side effects, including death. Be sure you know how to use fentanyl and what other drugs you should avoid using with it.<br /><br />See also Drug Interactions section. Get medical help right away if any of these very serious side effects occur: slow/shallow breathing, unusual lightheadedness, severe drowsiness/dizziness, difficulty waking up. Do not use this medication to relieve mild, short-term, or sudden pain (such as due to headache/migraine, dental/medical procedures), or pain after surgery (including same-day surgery when you do not need to stay in the hospital overnight).<br /><br />This medication is not for occasional ("as needed") use. Since they are not used the same way, different forms of fentanyl (including lozenges, buccal tablets, patches) do not have the same effects at equal strengths and should not be substituted for each other. Tell your doctor or pharmacist of all medications that you use, especially of drugs that can affect how fentanyl works.<br /><br />Do not start, stop, or change the dosage of any medicines you are using without your doctor's approval. Carefully follow the manufacturer's instructions for using fentanyl transdermal patches. The patches are for use on the skin only.<br /><br />Raising your skin/body temperature, using cut or damaged fentanyl patches, or using the patch improperly (such as by chewing it) may cause fatal overdose. Avoid increasing your skin temperature at/near the application site by using products such as heating pads, electric blankets, hot tubs, heat lamps, or tanning lamps. Avoid taking hot baths and sunbathing.<br /><br />However, you may bathe, shower, or swim while wearing the patch as long as you avoid hot water. Before using this medication, women of childbearing age should talk with their doctor(s) about the risks and benefits. Tell your doctor if you are pregnant or if you plan to become pregnant.<br /><br /> During pregnancy, this medication should be used only when clearly needed. It may slightly increase the risk of birth defects if used during the first two months of pregnancy. Also, using it for a long time or in high doses near the expected delivery date may harm the unborn baby.<br /><br />To lessen the risk, use the smallest effective dose for the shortest possible time. Babies born to mothers who use this drug for a long time may develop severe (possibly fatal) withdrawal symptoms. Tell the doctor right away if you notice any symptoms in your newborn baby such as crying that doesn't stop, slow/shallow breathing, irritability, shaking, vomiting, diarrhea, poor feeding, or difficulty gaining weight.<br /><br /> Keep this medicine in a safe place to prevent theft, misuse, or abuse. This medication is not recommended for use in children younger than 2 years. Some manufacturers recommend that this product should not be used in children younger than 18 years. If someone accidentally swallows this drug, get medical help right away.
| Chronic pain with opioid tolerance | |
| G89.2 | Chronic pain, not elsewhere classified |
| G89.21 | Chronic pain due to trauma |
| G89.22 | Chronic post-thoracotomy pain |
| G89.28 | Other chronic postprocedural pain |
| G89.29 | Other chronic pain |
| G89.3 | Neoplasm related pain (acute) (chronic) |
| Z79.891 | Long term (current) use of opiate analgesic |
| Severe pain with opioid tolerance | |
| G89.1 | Acute pain, not elsewhere classified |
| G89.11 | Acute pain due to trauma |
| G89.12 | Acute post-thoracotomy pain |
| G89.18 | Other acute postprocedural pain |
| G89.2 | Chronic pain, not elsewhere classified |
| G89.21 | Chronic pain due to trauma |
| G89.22 | Chronic post-thoracotomy pain |
| G89.28 | Other chronic postprocedural pain |
| G89.29 | Other chronic pain |
| G89.3 | Neoplasm related pain (acute) (chronic) |
| M25.5 | Pain in joint |
| M25.50 | Pain in unspecified joint |
| M25.51 | Pain in shoulder |
| M25.511 | Pain in right shoulder |
| M25.512 | Pain in left shoulder |
| M25.519 | Pain in unspecified shoulder |
| M25.52 | Pain in elbow |
| M25.521 | Pain in right elbow |
| M25.522 | Pain in left elbow |
| M25.529 | Pain in unspecified elbow |
| M25.53 | Pain in wrist |
| M25.531 | Pain in right wrist |
| M25.532 | Pain in left wrist |
| M25.539 | Pain in unspecified wrist |
| M25.55 | Pain in hip |
| M25.551 | Pain in right hip |
| M25.552 | Pain in left hip |
| M25.559 | Pain in unspecified hip |
| M25.56 | Pain in knee |
| M25.561 | Pain in right knee |
| M25.562 | Pain in left knee |
| M25.569 | Pain in unspecified knee |
| M25.57 | Pain in ankle and joints of foot |
| M25.571 | Pain in right ankle and joints of right foot |
| M25.572 | Pain in left ankle and joints of left foot |
| M25.579 | Pain in unspecified ankle and joints of unspecified foot |
| M26.62 | Arthralgia of temporomandibular joint |
| M54.5 | Low back pain |
| M54.6 | Pain in thoracic spine |
| M79.6 | Pain in limb, hand, foot, fingers and toes |
| M79.60 | Pain in limb, unspecified |
| M79.601 | Pain in right arm |
| M79.602 | Pain in left arm |
| M79.603 | Pain in arm, unspecified |
| M79.604 | Pain in right leg |
| M79.605 | Pain in left leg |
| M79.606 | Pain in leg, unspecified |
| M79.609 | Pain in unspecified limb |
| M79.62 | Pain in upper arm |
| M79.621 | Pain in right upper arm |
| M79.622 | Pain in left upper arm |
| M79.629 | Pain in unspecified upper arm |
| M79.63 | Pain in forearm |
| M79.631 | Pain in right forearm |
| M79.632 | Pain in left forearm |
| M79.639 | Pain in unspecified forearm |
| M79.64 | Pain in hand and fingers |
| M79.641 | Pain in right hand |
| M79.642 | Pain in left hand |
| M79.643 | Pain in unspecified hand |
| M79.644 | Pain in right finger(s) |
| M79.645 | Pain in left finger(s) |
| M79.646 | Pain in unspecified finger(s) |
| M79.65 | Pain in thigh |
| M79.651 | Pain in right thigh |
| M79.652 | Pain in left thigh |
| M79.659 | Pain in unspecified thigh |
| M79.66 | Pain in lower leg |
| M79.661 | Pain in right lower leg |
| M79.662 | Pain in left lower leg |
| M79.669 | Pain in unspecified lower leg |
| M79.67 | Pain in foot and toes |
| M79.671 | Pain in right foot |
| M79.672 | Pain in left foot |
| M79.673 | Pain in unspecified foot |
| M79.674 | Pain in right toe(s) |
| M79.675 | Pain in left toe(s) |
| M79.676 | Pain in unspecified toe(s) |
| R52 | Pain, unspecified |
| R68.84 | Jaw pain |
| Z79.891 | Long term (current) use of opiate analgesic |
| 0-9 | A-Z |
|---|---|
| G89.1 | Acute pain, not elsewhere classified |
| G89.11 | Acute pain due to trauma |
| G89.12 | Acute post-thoracotomy pain |
| G89.18 | Other acute postprocedural pain |
| G89.2 | Chronic pain, not elsewhere classified |
| G89.2 | Chronic pain, not elsewhere classified |
| G89.21 | Chronic pain due to trauma |
| G89.21 | Chronic pain due to trauma |
| G89.22 | Chronic post-thoracotomy pain |
| G89.22 | Chronic post-thoracotomy pain |
| G89.28 | Other chronic postprocedural pain |
| G89.28 | Other chronic postprocedural pain |
| G89.29 | Other chronic pain |
| G89.29 | Other chronic pain |
| G89.3 | Neoplasm related pain (acute) (chronic) |
| G89.3 | Neoplasm related pain (acute) (chronic) |
| M25.5 | Pain in joint |
| M25.50 | Pain in unspecified joint |
| M25.51 | Pain in shoulder |
| M25.511 | Pain in right shoulder |
| M25.512 | Pain in left shoulder |
| M25.519 | Pain in unspecified shoulder |
| M25.52 | Pain in elbow |
| M25.521 | Pain in right elbow |
| M25.522 | Pain in left elbow |
| M25.529 | Pain in unspecified elbow |
| M25.53 | Pain in wrist |
| M25.531 | Pain in right wrist |
| M25.532 | Pain in left wrist |
| M25.539 | Pain in unspecified wrist |
| M25.55 | Pain in hip |
| M25.551 | Pain in right hip |
| M25.552 | Pain in left hip |
| M25.559 | Pain in unspecified hip |
| M25.56 | Pain in knee |
| M25.561 | Pain in right knee |
| M25.562 | Pain in left knee |
| M25.569 | Pain in unspecified knee |
| M25.57 | Pain in ankle and joints of foot |
| M25.571 | Pain in right ankle and joints of right foot |
| M25.572 | Pain in left ankle and joints of left foot |
| M25.579 | Pain in unspecified ankle and joints of unspecified foot |
| M26.62 | Arthralgia of temporomandibular joint |
| M54.5 | Low back pain |
| M54.6 | Pain in thoracic spine |
| M79.6 | Pain in limb, hand, foot, fingers and toes |
| M79.60 | Pain in limb, unspecified |
| M79.601 | Pain in right arm |
| M79.602 | Pain in left arm |
| M79.603 | Pain in arm, unspecified |
| M79.604 | Pain in right leg |
| M79.605 | Pain in left leg |
| M79.606 | Pain in leg, unspecified |
| M79.609 | Pain in unspecified limb |
| M79.62 | Pain in upper arm |
| M79.621 | Pain in right upper arm |
| M79.622 | Pain in left upper arm |
| M79.629 | Pain in unspecified upper arm |
| M79.63 | Pain in forearm |
| M79.631 | Pain in right forearm |
| M79.632 | Pain in left forearm |
| M79.639 | Pain in unspecified forearm |
| M79.64 | Pain in hand and fingers |
| M79.641 | Pain in right hand |
| M79.642 | Pain in left hand |
| M79.643 | Pain in unspecified hand |
| M79.644 | Pain in right finger(s) |
| M79.645 | Pain in left finger(s) |
| M79.646 | Pain in unspecified finger(s) |
| M79.65 | Pain in thigh |
| M79.651 | Pain in right thigh |
| M79.652 | Pain in left thigh |
| M79.659 | Pain in unspecified thigh |
| M79.66 | Pain in lower leg |
| M79.661 | Pain in right lower leg |
| M79.662 | Pain in left lower leg |
| M79.669 | Pain in unspecified lower leg |
| M79.67 | Pain in foot and toes |
| M79.671 | Pain in right foot |
| M79.672 | Pain in left foot |
| M79.673 | Pain in unspecified foot |
| M79.674 | Pain in right toe(s) |
| M79.675 | Pain in left toe(s) |
| M79.676 | Pain in unspecified toe(s) |
| R52 | Pain, unspecified |
| R68.84 | Jaw pain |
| Z79.891 | Long term (current) use of opiate analgesic |
| Z79.891 | Long term (current) use of opiate analgesic |
Formulary Reference Tool