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PHENDIMETRAZINE TARTRATE (phendimetrazine tartrate)
- Weight loss management for obese patient (bmi >= 30)
35 mg tablet
- 1 tablet (35 mg) by oral route 3 times per day 1 hour before meal(s)
35 mg tablet
- 1 tablet (35 mg) by oral route 3 times per day 1 hour before meal(s)
Weight loss management for obese patient (bmi >= 30)
- 1 tablet (35 mg) by oral route 2 times per day 1 hour before meal(s)
- 1 tablet (35 mg) by oral route 3 times per day 1 hour before meal(s)
- 2 tablets (70 mg) by oral route 3 times per day
- isocarboxazid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- tranylcypromine
Contraindicated
- amitriptyline
- amitriptyline-chlordiazepoxide
- amoxapine
- Amrix
- Anafranil
- Azilect
- bromocriptine
- cabergoline
- Cafergot
- clomipramine
- Compound 347
- cyclobenzaprine
- cyclobenzaprine with msm
- Cycloset
- D.h.e.45
- desipramine
- dihydroergotamine
- doxepin
- Eldepryl
- enflurane
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- Forane
- imipramine HCl
- imipramine pamoate
- isoflurane
- linezolid
- maprotiline
- methylergonovine
- Migergot
- Migranal
- Norpramin
- nortriptyline
- Pamelor
- Parlodel
- perphenazine-amitriptyline
- protriptyline
- Prudoxin
- rasagiline
- selegiline HCl
- sevoflurane
- Silenor
- Sojourn
- Surmontil
- Tabradol
- Terrell
- Tofranil
- Tofranil-pm
- trimipramine
- Ultane
- Vivactil
- Zelapar
- Zonalon
- Zyvox
Severe
Moderate
- None
- Cardiac arrhythmia
- Cerebrovascular accident
- Chronic heart failure
- Coronary artery disease
- Drug abuse
- Glaucoma
- Hyperthyroidism
- Lactating mother
- Pregnancy
- Pulmonary hypertension
- Severe uncontrolled hypertension
Contraindicated
- Moderate hypertension
- Psychotic disorder
- Valvular heart disease
Severe
Moderate
- Diabetes mellitus
PHENDIMETRAZINE TARTRATE (phendimetrazine tartrate)
- Weight loss management for obese patient (bmi >= 30)
- Hypertension
- Dysgeusia
- Insomnia
- Nervousness
- Xerostomia
More Frequent
Severe
Less Severe
- Allergic dermatitis
- Cardiac arrhythmia
- Urticaria
- Acute abdominal pain
- Agitation
- Blurred vision
- Constipation
- Diarrhea
- Dizziness
- Dysuria
- Euphoria
- Flushing
- Headache disorder
- Libido changes
- Palpitations
- Skin rash
- Tachycardia
- Tremor
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Drug-induced psychosis
- Myocardial ischemia
- Pulmonary hypertension
- Valvular heart disease
Less Severe
- Dysphoric mood
- Erectile dysfunction
- Hyperhidrosis
- Increased urinary frequency
- Nausea
Contraindicated
None
Severe Precaution
Phendimetrazine
Not recommended for children under 12 years. Safety has not been established.
- 1 Day – 12 Years
- Not recommended for children under 12 years. Safety has not been established.
Management or Monitoring Precaution
None
Phendimetrazine
- Severity Level:
X
- Additional Notes: Weight loss not recommended in pregnancy may cause harm to fetus
Contraindicated
Phendimetrazine
Insuff data avail; based on pharmacology, potential for adverse effects
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Insuff data avail; based on pharmacology, potential for adverse effects |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Phendimetrazine
Cardiovascular-Limited usage data in the elderly. Contraindicated in severe hypertension, coronary insufficiency or peripheral vascular disease. Neuro/Psych-May worsen insomnia. Ocular-Contraindicated in glaucoma
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Weight loss management for obese patient (bmi >= 30) | |
| E66 | Overweight and obesity |
| E66.0 | Obesity due to excess calories |
| E66.01 | Morbid (severe) obesity due to excess calories |
| E66.09 | Other obesity due to excess calories |
| E66.1 | Drug-induced obesity |
| E66.2 | Morbid (severe) obesity with alveolar hypoventilation |
| E66.8 | Other obesity |
| E66.9 | Obesity, unspecified |
| Z68.3 | Body mass index (BMi) 30-39, adult |
| Z68.30 | Body mass index (BMi) 30.0-30.9, adult |
| Z68.31 | Body mass index (BMi) 31.0-31.9, adult |
| Z68.32 | Body mass index (BMi) 32.0-32.9, adult |
| Z68.33 | Body mass index (BMi) 33.0-33.9, adult |
| Z68.34 | Body mass index (BMi) 34.0-34.9, adult |
| Z68.35 | Body mass index (BMi) 35.0-35.9, adult |
| Z68.36 | Body mass index (BMi) 36.0-36.9, adult |
| Z68.37 | Body mass index (BMi) 37.0-37.9, adult |
| Z68.38 | Body mass index (BMi) 38.0-38.9, adult |
| Z68.39 | Body mass index (BMi) 39.0-39.9, adult |
| Z68.4 | Body mass index (BMi) 40 or greater, adult |
| Z68.41 | Body mass index (BMi) 40.0-44.9, adult |
| Z68.42 | Body mass index (BMi) 45.0-49.9, adult |
| Z68.43 | Body mass index (BMi) 50.0-59.9, adult |
| Z68.44 | Body mass index (BMi) 60.0-69.9, adult |
| Z68.45 | Body mass index (BMi) 70 or greater, adult |
| 0-9 | A-Z |
|---|---|
| E66 | Overweight and obesity |
| E66.0 | Obesity due to excess calories |
| E66.01 | Morbid (severe) obesity due to excess calories |
| E66.09 | Other obesity due to excess calories |
| E66.1 | Drug-induced obesity |
| E66.2 | Morbid (severe) obesity with alveolar hypoventilation |
| E66.8 | Other obesity |
| E66.9 | Obesity, unspecified |
| Z68.3 | Body mass index (BMi) 30-39, adult |
| Z68.30 | Body mass index (BMi) 30.0-30.9, adult |
| Z68.31 | Body mass index (BMi) 31.0-31.9, adult |
| Z68.32 | Body mass index (BMi) 32.0-32.9, adult |
| Z68.33 | Body mass index (BMi) 33.0-33.9, adult |
| Z68.34 | Body mass index (BMi) 34.0-34.9, adult |
| Z68.35 | Body mass index (BMi) 35.0-35.9, adult |
| Z68.36 | Body mass index (BMi) 36.0-36.9, adult |
| Z68.37 | Body mass index (BMi) 37.0-37.9, adult |
| Z68.38 | Body mass index (BMi) 38.0-38.9, adult |
| Z68.39 | Body mass index (BMi) 39.0-39.9, adult |
| Z68.4 | Body mass index (BMi) 40 or greater, adult |
| Z68.41 | Body mass index (BMi) 40.0-44.9, adult |
| Z68.42 | Body mass index (BMi) 45.0-49.9, adult |
| Z68.43 | Body mass index (BMi) 50.0-59.9, adult |
| Z68.44 | Body mass index (BMi) 60.0-69.9, adult |
| Z68.45 | Body mass index (BMi) 70 or greater, adult |
Formulary Reference Tool