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PHENDIMETRAZINE TARTRATE ER (phendimetrazine tartrate)
- Weight loss management for obese patient (bmi >= 30)
- Wt loss mgmt, pt with bmi 27-29 & wt-related comorbidity
105 mg capsule,extended release
- 1 capsule (105 mg) by oral route once daily 30-60 minutes beforethe morning meal
ER 105 mg capsule,extended release
- 1 capsule (105 mg) by oral route once daily 30-60 minutes beforethe morning meal
ER 105 mg capsule,extended release
- 1 capsule (105 mg) by oral route once daily 30-60 minutes beforethe morning meal
Weight loss management for obese patient (bmi >= 30)
- 1 capsule (105 mg) by oral route once daily 30-60 minutes beforethe morning meal
Wt loss mgmt, pt with bmi 27-29 & wt-related comorbidity
- 1 capsule (105 mg) by oral route once daily 30-60 minutes beforethe morning meal
- isocarboxazid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- tranylcypromine
Contraindicated
- amitriptyline
- amitriptyline-chlordiazepoxide
- amoxapine
- Amrix
- Anafranil
- Azilect
- bromocriptine
- cabergoline
- Cafergot
- clomipramine
- Compound 347
- cyclobenzaprine
- cyclobenzaprine with msm
- Cycloset
- D.h.e.45
- desipramine
- dihydroergotamine
- doxepin
- Eldepryl
- enflurane
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- Forane
- imipramine HCl
- imipramine pamoate
- isoflurane
- linezolid
- maprotiline
- methylergonovine
- Migergot
- Migranal
- Norpramin
- nortriptyline
- Pamelor
- Parlodel
- perphenazine-amitriptyline
- protriptyline
- Prudoxin
- rasagiline
- selegiline HCl
- sevoflurane
- Silenor
- Sojourn
- Surmontil
- Tabradol
- Terrell
- Tofranil
- Tofranil-pm
- trimipramine
- Ultane
- Vivactil
- Zelapar
- Zonalon
- Zyvox
Severe
Moderate
- None
- Cardiac arrhythmia
- Cerebrovascular accident
- Chronic heart failure
- Coronary artery disease
- Drug abuse
- Glaucoma
- Hyperthyroidism
- Lactating mother
- Pregnancy
- Pulmonary hypertension
- Severe uncontrolled hypertension
Contraindicated
- Moderate hypertension
- Psychotic disorder
- Valvular heart disease
Severe
Moderate
- Diabetes mellitus
PHENDIMETRAZINE TARTRATE ER (phendimetrazine tartrate)
- Weight loss management for obese patient (bmi >= 30)
- Wt loss mgmt, pt with bmi 27-29 & wt-related comorbidity
- Hypertension
- Dysgeusia
- Insomnia
- Nervousness
- Xerostomia
More Frequent
Severe
Less Severe
- Allergic dermatitis
- Cardiac arrhythmia
- Urticaria
- Acute abdominal pain
- Agitation
- Blurred vision
- Constipation
- Diarrhea
- Dizziness
- Dysuria
- Euphoria
- Flushing
- Headache disorder
- Libido changes
- Palpitations
- Skin rash
- Tachycardia
- Tremor
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Drug-induced psychosis
- Myocardial ischemia
- Pulmonary hypertension
- Valvular heart disease
Less Severe
- Dysphoric mood
- Erectile dysfunction
- Hyperhidrosis
- Increased urinary frequency
- Nausea
Contraindicated
None
Severe Precaution
Phendimetrazine (ER)
No safety and efficacy. Long acting form not recommended for short term therapy. Risks with underlying cardiac structural abnormalities. Pulmonary hypertension with extended use.
- 1 Day – 17 Years
- No safety and efficacy. Long acting form not recommended for short term therapy. Risks with underlying cardiac structural abnormalities. Pulmonary hypertension with extended use.
Management or Monitoring Precaution
None
Phendimetrazine
- Severity Level:
X
- Additional Notes: Weight loss not recommended in pregnancy may cause harm to fetus
Contraindicated
Phendimetrazine
Insuff data avail; based on pharmacology, potential for adverse effects
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Insuff data avail; based on pharmacology, potential for adverse effects |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Weight loss management for obese patient (bmi >= 30) | |
| E66 | Overweight and obesity |
| E66.0 | Obesity due to excess calories |
| E66.01 | Morbid (severe) obesity due to excess calories |
| E66.09 | Other obesity due to excess calories |
| E66.1 | Drug-induced obesity |
| E66.2 | Morbid (severe) obesity with alveolar hypoventilation |
| E66.8 | Other obesity |
| E66.9 | Obesity, unspecified |
| Z68.3 | Body mass index (BMi) 30-39, adult |
| Z68.30 | Body mass index (BMi) 30.0-30.9, adult |
| Z68.31 | Body mass index (BMi) 31.0-31.9, adult |
| Z68.32 | Body mass index (BMi) 32.0-32.9, adult |
| Z68.33 | Body mass index (BMi) 33.0-33.9, adult |
| Z68.34 | Body mass index (BMi) 34.0-34.9, adult |
| Z68.35 | Body mass index (BMi) 35.0-35.9, adult |
| Z68.36 | Body mass index (BMi) 36.0-36.9, adult |
| Z68.37 | Body mass index (BMi) 37.0-37.9, adult |
| Z68.38 | Body mass index (BMi) 38.0-38.9, adult |
| Z68.39 | Body mass index (BMi) 39.0-39.9, adult |
| Z68.4 | Body mass index (BMi) 40 or greater, adult |
| Z68.41 | Body mass index (BMi) 40.0-44.9, adult |
| Z68.42 | Body mass index (BMi) 45.0-49.9, adult |
| Z68.43 | Body mass index (BMi) 50.0-59.9, adult |
| Z68.44 | Body mass index (BMi) 60.0-69.9, adult |
| Z68.45 | Body mass index (BMi) 70 or greater, adult |
| Wt loss mgmt, pt with bmi 27-29 & wt-related comorbidity | |
| E66.3 | Overweight |
| Z68.27 | Body mass index (BMi) 27.0-27.9, adult |
| Z68.28 | Body mass index (BMi) 28.0-28.9, adult |
| Z68.29 | Body mass index (BMi) 29.0-29.9, adult |
| 0-9 | A-Z |
|---|---|
| E66 | Overweight and obesity |
| E66.0 | Obesity due to excess calories |
| E66.01 | Morbid (severe) obesity due to excess calories |
| E66.09 | Other obesity due to excess calories |
| E66.1 | Drug-induced obesity |
| E66.2 | Morbid (severe) obesity with alveolar hypoventilation |
| E66.3 | Overweight |
| E66.8 | Other obesity |
| E66.9 | Obesity, unspecified |
| Z68.27 | Body mass index (BMi) 27.0-27.9, adult |
| Z68.28 | Body mass index (BMi) 28.0-28.9, adult |
| Z68.29 | Body mass index (BMi) 29.0-29.9, adult |
| Z68.3 | Body mass index (BMi) 30-39, adult |
| Z68.30 | Body mass index (BMi) 30.0-30.9, adult |
| Z68.31 | Body mass index (BMi) 31.0-31.9, adult |
| Z68.32 | Body mass index (BMi) 32.0-32.9, adult |
| Z68.33 | Body mass index (BMi) 33.0-33.9, adult |
| Z68.34 | Body mass index (BMi) 34.0-34.9, adult |
| Z68.35 | Body mass index (BMi) 35.0-35.9, adult |
| Z68.36 | Body mass index (BMi) 36.0-36.9, adult |
| Z68.37 | Body mass index (BMi) 37.0-37.9, adult |
| Z68.38 | Body mass index (BMi) 38.0-38.9, adult |
| Z68.39 | Body mass index (BMi) 39.0-39.9, adult |
| Z68.4 | Body mass index (BMi) 40 or greater, adult |
| Z68.41 | Body mass index (BMi) 40.0-44.9, adult |
| Z68.42 | Body mass index (BMi) 45.0-49.9, adult |
| Z68.43 | Body mass index (BMi) 50.0-59.9, adult |
| Z68.44 | Body mass index (BMi) 60.0-69.9, adult |
| Z68.45 | Body mass index (BMi) 70 or greater, adult |
Formulary Reference Tool