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SELZENTRY (MARAVIROC)
- CCr5 tropic HIV infection
150 mg tablet
- 1 tablet (150 mg) by oral route 2 times per day
25 mg tablet
- Dosage information is not available
300 mg tablet
- 1 tablet (300 mg) by oral route 2 times per day
75 mg tablet
- Dosage information is not available
20 mg/mL oral solution
- 15 milliliters (300 mg) by oral route 2 times per day
CCr5 tropic HIV infection
- 1 tablet (150 mg) by oral route 2 times per day
- 7.5 milliliters (150 mg) by oral route 2 times per day
- 2 tablets (300 mg) by oral route 2 times per day
- 1 tablet (300 mg) by oral route 2 times per day
- 15 milliliters (300 mg) by oral route 2 times per day
- 2 tablets (600 mg) by oral route 2 times per day
- 30 milliliters (600 mg) by oral route 2 times per day
- B cplx-C-St.Johnwrt-K.&S.ginsg
- calcium-mag-B complex-D3-hrb61
- Cold & Flu Fighter
- Fatigue Relief Complex
- St. John's wort
- vit C-St. John wort-elder-hb30
- Women's Complex
Contraindicated
- amoxicil-clarithromy-lansopraz
- Aptivus
- atazanavir
- Atripla
- Belladonna-phenobarbital
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- boceprevir
- carbamazepine
- Carbatrol
- Cerebyx
- clarithromycin
- conivaptan in 5 % dextrose
- Crixivan
- darunavir
- delavirdine
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Donnatal
- efavirenz
- efavirenz-emtricitabin-tenofov
- elvitegr-cobicist-emtric-tenof
- enzalutamide
- Epitol
- Equetro
- etravirine
- fosamprenavir
- fosphenytoin
- Incivek
- indinavir
- Intelence
- Invirase
- isoniazid-rifamp-pyrazinamide
- itraconazole
- Kaletra
- Ketek
- ketoconazole
- Lexiva
- lopinavir-ritonavir
- Luminal
- Mysoline
- nefazodone
- nelfinavir
- Norvir
- Norvir Soft Gelatin
- Noxafil
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Onmel
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- posaconazole
- Prevpac
- Prezista
- primidone
- Rescriptor
- Reyataz
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- ritonavir
- saquinavir mesylate
- Sporanox
- Sporanox Pulsepak
- Stribild
- Sustiva
- Tegretol
- Tegretol Xr
- telaprevir
- telithromycin
- tipranavir
- Vaprisol
- Victrelis
- Viracept
- Xtandi
Severe
Moderate
- None
- Chronic kidney disease stage 4 (severe) GFR 15-29 ml/min
- Chronic kidney disease stage 5 (failure) GFr<15 ml/min
- Lactating mother
Contraindicated
- Acute myocardial infarction
- Disease of liver
- Drug-induced hepatitis
- Kidney disease with likely reduction in GFR
- Myocardial ischemia
- Viral hepatitis C
Severe
Moderate
- Coronary artery disease
- Increased cardiovascular event risk
- Infection
- Orthostatic hypotension
SELZENTRY (MARAVIROC)
- CCr5 tropic HIV infection
- Avascular necrosis of bone
- Upper respiratory infection
- Cough
- Diarrhea
- Dizziness
- Fever
- Headache disorder
- Nausea
- Skin rash
More Frequent
Severe
Less Severe
- Bronchospastic pulmonary disease
- Dysesthesia
- Edema
- Hyperbilirubinemia
- Increased alanine transaminase
- Increased aspartate transaminase
- Infection
- Paresthesia
- Peripheral neuropathy
- Respiration changes
- Stomatitis
- Acute abdominal pain
- Appetite changes
- Arthralgias
- Condylomata acuminata
- Conjunctivitis
- Constipation
- Depression
- Dyspepsia
- Folliculitis
- Herpes simplex infection
- Lipodystrophy
- Myalgias
- Myositis
- Pain
- Pruritus of skin
- Sinusitis
- Skin inflammation
- Sleep disorder
- Syncope
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute myocardial infarction
- Anemia
- Bone marrow depression
- Bronchitis
- Cerebrovascular accident
- Clostridium difficile infection
- Coronary artery disease
- Coronary artery occlusion
- Endocarditis
- Eosinophilia
- Graves' disease
- Guillain-barre syndrome
- Hepatic cirrhosis
- Hepatic failure
- Hepatitis
- Hypertension
- Hypoplastic anemia
- Malignancy
- Myocardial ischemia
- Neoplasm
- Obstructive hyperbilirubinemia
- Polymyositis
- Rhabdomyolysis
- Seizure disorder
- Stevens-johnson syndrome
- Toxic epidermal necrolysis
- Unstable angina pectoris
Less Severe
- Altered consciousness
- Facial palsy
- Orthostatic hypotension
- Otitis
- Symptoms of anxiety
- Tremor
- Visual field defect
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Maraviroc
Not studied age < 2 years, no safety and efficacy.
- 1 Day – 2 Years
- Not studied age < 2 years, no safety and efficacy.
Maraviroc
- Severity Level:
2
- Additional Notes: Insuff human data animal data does not sug dev tox
Contraindicated
Maraviroc
Cdc does not recommend breastfeeding in hiv-positive women
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Cdc does not recommend breastfeeding in hiv-positive women |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Maraviroc
Cardiovascular-Caution in patients at risk for cardiovascular events. Monitor for hypotension. Renal-Follow dosing recommendations for CrCl < 50mL/min. May be at increased risk for orthostatic hypotension.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- This medication may rarely cause serious liver problems. Symptoms of a serious allergic reaction may occur before liver problems develop. Get medical help right away if you have any symptoms of a serious allergic reaction or possible liver damage such as: rash, persistent nausea/vomiting, yellowing eyes/skin, dark urine, extreme tiredness. (See also Side Effects section.)
| CCr5 tropic HIV infection | |
| B20 | Human immunodeficiency virus [HIv] disease |
| O98.7 | Human immunodeficiency virus [HIv] disease complicating pregnancy, childbirth and the puerperium |
| O98.71 | Human immunodeficiency virus [HIv] disease complicating pregnancy |
| O98.711 | Human immunodeficiency virus [HIv] disease complicating pregnancy, first trimester |
| O98.712 | Human immunodeficiency virus [HIv] disease complicating pregnancy, second trimester |
| O98.713 | Human immunodeficiency virus [HIv] disease complicating pregnancy, third trimester |
| O98.719 | Human immunodeficiency virus [HIv] disease complicating pregnancy, unspecified trimester |
| O98.72 | Human immunodeficiency virus [HIv] disease complicating childbirth |
| O98.73 | Human immunodeficiency virus [HIv] disease complicating the puerperium |
| Z21 | Asymptomatic human immunodeficiency virus [HIv] infection status |
| 0-9 | A-Z |
|---|---|
| B20 | Human immunodeficiency virus [HIv] disease |
| O98.7 | Human immunodeficiency virus [HIv] disease complicating pregnancy, childbirth and the puerperium |
| O98.71 | Human immunodeficiency virus [HIv] disease complicating pregnancy |
| O98.711 | Human immunodeficiency virus [HIv] disease complicating pregnancy, first trimester |
| O98.712 | Human immunodeficiency virus [HIv] disease complicating pregnancy, second trimester |
| O98.713 | Human immunodeficiency virus [HIv] disease complicating pregnancy, third trimester |
| O98.719 | Human immunodeficiency virus [HIv] disease complicating pregnancy, unspecified trimester |
| O98.72 | Human immunodeficiency virus [HIv] disease complicating childbirth |
| O98.73 | Human immunodeficiency virus [HIv] disease complicating the puerperium |
| Z21 | Asymptomatic human immunodeficiency virus [HIv] infection status |
Formulary Reference Tool