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LEXIVA (FOSAMPRENAVIR CALCIUM)
- HIV infection
700 mg tablet
- 1 tablet (700 mg) by oral route 2 times per day
50 mg/mL oral suspension
- 14 milliliters (700 mg) by oral route 2 times per day on an empty stomach
50 mg/mL oral suspension
- 14 milliliters (700 mg) by oral route 2 times per day on an empty stomach
fosamprenavir 700 mg tablet
- 1 tablet (700 mg) by oral route 2 times per day
HIV infection
- 2 tablets (1,400 mg) by oral route 2 times per day
- 2 tablets (1,400 mg) by oral route once daily
- 28 milliliters (1,400 mg) by oral route once daily on an empty stomach
- 28 milliliters (1,400 mg) by oral route 2 times per day on an empty stomach
- 14 milliliters (700 mg) by oral route 2 times per day on an empty stomach
- 1 tablet (700 mg) by oral route 2 times per day
- Advicor
- alfuzosin
- Altoprev
- B cplx-C-St.Johnwrt-K.&S.ginsg
- bromocriptine
- cabergoline
- Cafergot
- calcium-mag-B complex-D3-hrb61
- Cold & Flu Fighter
- Cycloset
- D.h.e.45
- delavirdine
- dihydroergotamine
- dutasteride-tamsulosin
- elvitegr-cobicist-emtric-tenof
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- etravirine
- ezetimibe-simvastatin
- Fatigue Relief Complex
- Flomax
- Intelence
- isoniazid-rifamp-pyrazinamide
- Jalyn
- Juxtapid
- lomitapide
- lovastatin
- methylergonovine
- Mevacor
- midazolam
- midazolam (PF)
- Migergot
- Migranal
- niacin-lovastatin
- niacin-simvastatin
- Orap
- Parlodel
- pimozide
- Rapaflo
- Rescriptor
- Revatio
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- sildenafil
- silodosin
- Simcor
- simvastatin
- St. John's wort
- Stribild
- tamsulosin
- triazolam
- Uroxatral
- vit C-St. John wort-elder-hb30
- Vytorin 10-10
- Vytorin 10-20
- Vytorin 10-40
- Vytorin 10-80
- Women's Complex
- Zocor
Contraindicated
- Advair Diskus
- Advair Hfa
- Altavera (28)
- Alyacen 1/35 (28)
- Alyacen 7/7/7 (28)
- Amethia
- Amethia Lo
- Amethyst
- Apri
- Aranelle (28)
- Astagraf Xl
- Aubra
- Aviane
- Azurette (28)
- B6-FA-B12-co Q10-herb no.225
- Balziva (28)
- Beauty & Skin Therapy
- Beyaz
- bosentan
- Bosulif
- bosutinib
- Brevicon (28)
- Briellyn
- Camila
- Camrese
- Camrese Lo
- carbamazepine
- Carbatrol
- Caziant (28)
- Chateal
- colchicine
- colchicine-probenecid
- Colcrys
- Cryselle (28)
- Cyclafem 1/35 (28)
- Cyclafem 7/7/7 (28)
- Cyclessa (28)
- cyclosporine
- cyclosporine modified
- Dasetta 1/35 (28)
- Dasetta 7/7/7 (28)
- Daysee
- Depo-provera
- Depo-subq Provera 104
- desog-e.estradiol/e.estradiol
- Desogen
- desogestrel-ethinyl estradiol
- dolutegravir
- drospirenone-e.estradiol-lm.FA
- drospirenone-ethinyl estradiol
- Elinest
- Emoquette
- Enpresse
- Enskyce
- Epitol
- Equetro
- Errin
- Estarylla
- estradiol valerate-dienogest
- Estrostep Fe-28
- ethynodiol diac-eth estradiol
- etonogestrel
- etonogestrel-ethinyl estradiol
- Falmina (28)
- Femcon Fe
- fluticasone-salmeterol
- Fortavit
- Generess Fe
- Gengraf
- Gianvi (28)
- Gildagia
- Gildess
- Gildess Fe
- Healthy Heart Complex
- Heather
- Hecoria
- ibrutinib
- Imbruvica
- Incivek
- Introvale
- Jencycla
- Jolessa
- Jolivette
- Junel 1.5/30 (21)
- Junel 1/20 (21)
- Junel Fe 1.5/30 (28)
- Junel Fe 1/20 (28)
- Kariva (28)
- Kelnor 1/35 (28)
- Kurvelo
- L norgest&E estradiol-E estrad
- Larin 1/20 (21)
- Larin Fe
- Leena 28
- Lessina
- Levonest (28)
- levonorg-eth estrad triphasic
- levonorgestrel
- levonorgestrel-ethinyl estrad
- Levora 0.15/30 (28)
- Levora-28
- Lo Loestrin Fe
- Loestrin 1.5/30 (21)
- Loestrin 1/20 (21)
- Loestrin Fe 1.5/30 (28)
- Loestrin Fe 1/20 (28)
- Lomedia 24 Fe
- Loryna (28)
- Loseasonique
- Low-ogestrel (28)
- Lutera (28)
- Lyza
- Marlissa
- Maximum Daily Green
- medroxyprogesterone
- Megavite
- Megavite Golden Years 55+
- Microgestin 1.5/30 (21)
- Microgestin 1/20 (21)
- Microgestin Fe 1.5/30 (28)
- Microgestin Fe 1/20 (28)
- Minastrin 24 Fe
- Mircette (28)
- Mirena
- Modicon (28)
- Mono-linyah
- Mononessa (28)
- MSM-collag-co Q10-herb no.226
- multivit-Fe-min-DNA-RNA-dsup4
- mv-iron-FA-Ca-beepoln-hb 101
- mv-mn-FA-herbs190&215-digest#4
- mv-mn-FA-lycopene-lut-#178herb
- mv-mn-iron-FA-herbal cmplx#190
- My Way
- Mycobutin
- Myzilra
- Natazia
- Necon 0.5/35 (28)
- Necon 1/35 (28)
- Necon 1/50 (28)
- Necon 10/11 (28)
- Necon 7/7/7 (28)
- Neoral
- nevirapine
- Nexplanon
- Next Choice One Dose
- Nor-qd
- Nora-be
- norelgestrom-ethinyl estradiol
- noreth-ethinyl estradiol-iron
- norethin-e.estradiol triphasic
- norethin-eth estrad biphasic
- norethindrone (contraceptive)
- norethindrone ac-eth estradiol
- norethindrone-e.estradiol-iron
- norethindrone-ethin estradiol
- norethindrone-mestranol
- norgestimate-ethinyl estradiol
- norgestrel-ethinyl estradiol
- Norinyl 1+35 (28)
- Norinyl 1+50 (28)
- Nortrel 0.5/35 (28)
- Nortrel 1/35 (21)
- Nortrel 1/35 (28)
- Nortrel 7/7/7 (28)
- Nuvaring
- Ocella
- Ogestrel (28)
- Oleptro Er
- Olysio
- Orsythia
- Ortho Evra
- Ortho Micronor
- Ortho Tri-cyclen (28)
- Ortho Tri-cyclen Lo (28)
- Ortho-cept (28)
- Ortho-cyclen (28)
- Ortho-novum 1/35 (28)
- Ortho-novum 7/7/7 (28)
- Ovcon-35 (28)
- Philith
- Pimtrea (28)
- Pirmella
- Plan B One-step
- policosan-inositol niac-garlic
- Policosanol-garlic-niacin
- Portia
- Previfem
- Priftin
- Prograf
- Quartette
- Quasense
- Rapamune
- Reclipsen (28)
- rifabutin
- rifapentine
- Safyral
- salmeterol
- Samsca
- Sandimmune
- Seasonique
- Serevent Diskus
- simeprevir
- sirolimus
- Skyla
- Sprintec (28)
- Sronyx
- Syeda
- tacrolimus
- Tegretol
- Tegretol Xr
- telaprevir
- temsirolimus
- Tilia Fe
- Tivicay
- tolvaptan
- Torisel
- Tracleer
- trazodone
- Tri-estarylla
- Tri-legest Fe
- Tri-linyah
- Tri-norinyl (28)
- Tri-previfem (28)
- Tri-sprintec (28)
- Trinessa (28)
- Trivora (28)
- Velivet Triphasic Regimen (28)
- Vestura (28)
- Viorele (28)
- Viramune
- Viramune Xr
- Vyfemla (28)
- Wera (28)
- Wymzya Fe
- Yasmin (28)
- Yaz 28
- Zarah
- Zenchent (28)
- Zenchent Fe
- Zeosa
- Zovia 1/35E (28)
- Zovia 1/50E (28)
Severe
Moderate
- Abstral
- Actiq
- Afinitor
- Afinitor Disperz
- Alfenta
- alfentanil
- amitriptyline
- amitriptyline-chlordiazepoxide
- amlodipine-atorvastatin
- amoxapine
- Amrix
- Anafranil
- Aptivus
- atorvastatin
- Atripla
- avanafil
- Belladonna-phenobarbital
- Caduet
- Cerebyx
- clomipramine
- Crestor
- cyclobenzaprine
- cyclobenzaprine with msm
- desipramine
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Donnatal
- doxepin
- Duragesic
- efavirenz
- efavirenz-emtricitabin-tenofov
- Endocet
- Endodan
- everolimus
- ezetimibe-atorvastatin
- fentanyl
- fentanyl citrate
- fentanyl citrate (PF)
- Fentora
- fosphenytoin
- ibuprofen-oxycodone
- imipramine HCl
- imipramine pamoate
- itraconazole
- ivacaftor
- Kaletra
- Kalydeco
- ketoconazole
- Latuda
- Lazanda
- Levitra
- Lipitor
- Liptruzet
- lopinavir-ritonavir
- Luminal
- lurasidone
- Mysoline
- Norpramin
- nortriptyline
- Norvir
- Norvir Soft Gelatin
- Noxafil
- Onmel
- Oxecta
- oxycodone
- oxycodone-acetaminophen
- oxycodone-aspirin
- Oxycontin
- Pamelor
- Percocet
- Percodan
- perphenazine-amitriptyline
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- posaconazole
- primidone
- Primlev
- protriptyline
- ritonavir
- rosuvastatin
- Roxicet
- Silenor
- Sporanox
- Sporanox Pulsepak
- Stendra
- Sublimaze (pf)
- Subsys
- Surmontil
- Sustiva
- Tabradol
- tipranavir
- Tofranil
- Tofranil-pm
- trimipramine
- vardenafil
- Viagra
- Vivactil
- Xartemis Xr
- Zortress
- Lactating mother
Contraindicated
- Acute myocardial infarction
- Coronary artery disease
- Disease of liver
- Increased cardiovascular event risk
- Kidney stone
- Tobacco smoker
Severe
Moderate
- Diabetes mellitus
- Hemolytic anemia
- Hemophilia
- Hypercholesterolemia
- Hypertriglyceridemia
LEXIVA (FOSAMPRENAVIR CALCIUM)
- HIV infection
- None
- Diarrhea
- Headache disorder
- Lipodystrophy associated with HIV
- Nausea
- Skin rash
- Vomiting
More Frequent
Severe
Less Severe
- Abnormal hepatic function tests
- Acute abdominal pain
- Fatigue
- Hyperglycemia
- Hypertriglyceridemia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute myocardial infarction
- Angioedema
- Diabetes mellitus
- Graves' disease
- Guillain-barre syndrome
- Hemolytic anemia
- Kidney stone
- Neutropenic disorder
- Polymyositis
- Stevens-johnson syndrome
Less Severe
- Hypercholesterolemia
- Oral hypoesthesia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Fosamprenavir
Safety and efficacy not established in pediatrics age < 4 weeks.
Higher incidence of vomiting and neutropenia in pediatric patients. Adhere to recommended dosing guidelines.
- 1 Day – 27 Days
- Safety and efficacy not established in pediatrics age < 4 weeks.
- Higher incidence of vomiting and neutropenia in pediatric patients. Adhere to recommended dosing guidelines.
- 28 Days – 18 Years
- Safety and efficacy not established in pediatrics age < 4 weeks.
- Higher incidence of vomiting and neutropenia in pediatric patients. Adhere to recommended dosing guidelines.
Fosamprenavir
- Severity Level:
2
- Additional Notes: Limited human data available
Contraindicated
Fosamprenavir
Cdc does not recommend breastfeeding in hiv-positive women.
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Cdc does not recommend breastfeeding in hiv-positive women. |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| HIV infection | |
| B20 | Human immunodeficiency virus [HIv] disease |
| B97.35 | Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere |
| O98.7 | Human immunodeficiency virus [HIv] disease complicating pregnancy, childbirth and the puerperium |
| O98.71 | Human immunodeficiency virus [HIv] disease complicating pregnancy |
| O98.711 | Human immunodeficiency virus [HIv] disease complicating pregnancy, first trimester |
| O98.712 | Human immunodeficiency virus [HIv] disease complicating pregnancy, second trimester |
| O98.713 | Human immunodeficiency virus [HIv] disease complicating pregnancy, third trimester |
| O98.719 | Human immunodeficiency virus [HIv] disease complicating pregnancy, unspecified trimester |
| O98.72 | Human immunodeficiency virus [HIv] disease complicating childbirth |
| O98.73 | Human immunodeficiency virus [HIv] disease complicating the puerperium |
| Z21 | Asymptomatic human immunodeficiency virus [HIv] infection status |
| 0-9 | A-Z |
|---|---|
| B20 | Human immunodeficiency virus [HIv] disease |
| B97.35 | Human immunodeficiency virus, type 2 [HIV 2] as the cause of diseases classified elsewhere |
| O98.7 | Human immunodeficiency virus [HIv] disease complicating pregnancy, childbirth and the puerperium |
| O98.71 | Human immunodeficiency virus [HIv] disease complicating pregnancy |
| O98.711 | Human immunodeficiency virus [HIv] disease complicating pregnancy, first trimester |
| O98.712 | Human immunodeficiency virus [HIv] disease complicating pregnancy, second trimester |
| O98.713 | Human immunodeficiency virus [HIv] disease complicating pregnancy, third trimester |
| O98.719 | Human immunodeficiency virus [HIv] disease complicating pregnancy, unspecified trimester |
| O98.72 | Human immunodeficiency virus [HIv] disease complicating childbirth |
| O98.73 | Human immunodeficiency virus [HIv] disease complicating the puerperium |
| Z21 | Asymptomatic human immunodeficiency virus [HIv] infection status |
Formulary Reference Tool