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ZOVIRAX (ACYCLOVIR)
- Mucocutaneous herpes simplex
- Genital herpes simplex
- Recurrent herpes simplex labialis
- Zovirax Topical Ointment
- Zovirax Topical Cream
- Acyclovir Topical Ointment
- Acyclovir Topical Cream
- By Indication
5 % topical ointment
- Apply to the affected area(s) by topical route every 3 hours 6 times per day
5 % topical cream
- Apply to the affected area(s) by topical route 5 times per day
5 % topical ointment
- Apply to the affected area(s) by topical route every 3 hours 6 times per day
5 % topical cream
- Apply to the affected area(s) by topical route 5 times per day
Genital herpes simplex
- Apply to the affected area(s) by topical route every 3 hours 6 times per day for 7 days
- Apply to the affected area(s) by topical route every 3 hours 6 times per day
Recurrent herpes simplex labialis
- Apply to the affected area(s) by topical route 5 times per day
- Apply to the affected area(s) by topical route 5 times per day for 4 days
- None
Contraindicated
- None
Severe
Moderate
- None
- None
Contraindicated
- None
Severe
Moderate
- No disease contraindications
ZOVIRAX (ACYCLOVIR)
- Mucocutaneous herpes simplex
- Genital herpes simplex
- Recurrent herpes simplex labialis
- None
- Abnormal desquamation
- Dry skin
- Skin irritation
- Stinging of skin
More Frequent
Severe
Less Severe
- None
- Cheilosis
- Pruritus of skin
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Angioedema
Less Severe
- Contact dermatitis
- Eczema
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Acyclovir (Topical)
Safety and efficacy not established age < 6 years.
- 1 Day – 6 Years
- Safety and efficacy not established age < 6 years.
Acyclovir
- Severity Level:
B
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Acyclovir (topical, Buccal)
Unlikely to be excreted since dose is small & systemic absorption is minimal
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Unknown | No adverse effect | Unlikely to be excreted since dose is small & systemic absorption is minimal |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Genital herpes simplex | |
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.01 | Herpesviral infection of penis |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.03 | Herpesviral cervicitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.9 | Anogenital herpesviral infection, unspecified |
| Mucocutaneous herpes simplex | |
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.01 | Herpesviral infection of penis |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.03 | Herpesviral cervicitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.1 | Herpesviral infection of perianal skin and rectum |
| A60.9 | Anogenital herpesviral infection, unspecified |
| B00.1 | Herpesviral vesicular dermatitis |
| B00.2 | Herpesviral gingivostomatitis and pharyngotonsillitis |
| B00.89 | Other herpesviral infection |
| Recurrent herpes simplex labialis | |
| B00.9 | Herpesviral infection, unspecified |
| 0-9 | A-Z |
|---|---|
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60 | Anogenital herpesviral [herpes simplex] infections |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.0 | Herpesviral infection of genitalia and urogenital tract |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.00 | Herpesviral infection of urogenital system, unspecified |
| A60.01 | Herpesviral infection of penis |
| A60.01 | Herpesviral infection of penis |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.02 | Herpesviral infection of other male genital organs |
| A60.03 | Herpesviral cervicitis |
| A60.03 | Herpesviral cervicitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.04 | Herpesviral vulvovaginitis |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.09 | Herpesviral infection of other urogenital tract |
| A60.1 | Herpesviral infection of perianal skin and rectum |
| A60.9 | Anogenital herpesviral infection, unspecified |
| A60.9 | Anogenital herpesviral infection, unspecified |
| B00.1 | Herpesviral vesicular dermatitis |
| B00.2 | Herpesviral gingivostomatitis and pharyngotonsillitis |
| B00.89 | Other herpesviral infection |
| B00.9 | Herpesviral infection, unspecified |
Formulary Reference Tool