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ONEXTON (CLINDAMYCIN PHOSPHATE/BENZOYL PEROXIDE)
- Acne vulgaris
1.2 % (1 % base)-3.75 % topical gel with pump
- Apply a pea-sized amount by topical route once daily to cover areas of face with thin layer
1.2 % (1 % base)-3.75 % topical gel
- Apply a pea-sized amount by topical route once daily to cover areas of face with thin layer
Acne vulgaris
- Apply a pea-sized amount by topical route once daily to cover areas of face with thin layer
- None
Contraindicated
- None
Severe
Moderate
- None
- Crohn's disease
- Ulcerative colitis
Contraindicated
- Clostridium difficile infection
- Exfoliative dermatitis
Severe
Moderate
- Atopic dermatitis
ONEXTON (CLINDAMYCIN PHOSPHATE/BENZOYL PEROXIDE)
- Acne vulgaris
- Erythema
- Pruritus of skin
- Abnormal desquamation
- Dry skin
- Skin irritation
More Frequent
Severe
Less Severe
- Skin irritation
- Skin rash
- Urticaria
- Abnormal desquamation
- Dry skin
- Erythema
- Headache disorder
- Oily skin
- Sensation of warmth
- Stinging of skin
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Bloody diarrhea
- Clostridium difficile infection
- Dermatitis due to topical drug
- Dyspnea
- Facial edema
- Hypersensitivity drug reaction
- Periorbital edema
- Pharyngeal edema
- Pruritus of skin
- Skin rash
- Syncope
- Throat constriction
- Urticaria
Less Severe
- Acute abdominal pain
- Contact dermatitis
- Diarrhea
- Dyschromia
- Gram-negative folliculitis
- Ocular pain
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Clindamycin (Topical)
Safety and efficacy not established age < 12 years.
- 1 Day – 12 Years
- Safety and efficacy not established age < 12 years.
Benzoyl Peroxide
- Severity Level:
C
- Additional Notes:
Clindamycin (top, Vag)
- Severity Level:
2
- Additional Notes: Insuff human and animal data available
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Benzoyl Peroxide
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
Clindamycin (top, Vag)
Avoiding nipple area application will reduce infants risk for diarrhea
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Unknown | Not known; no or inclusive data | Avoiding nipple area application will reduce infants risk for diarrhea |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Acne vulgaris | |
| L70.0 | Acne vulgaris |
| 0-9 | A-Z |
|---|---|
| L70.0 | Acne vulgaris |
Formulary Reference Tool