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MEPHYTON (PHYTONADIONE)
- Hypoprothrombinemia
- Antibiotic-induced hypoprothrombinemia
- Anticoagulant-induced prothrombin deficiency
- Vitamin K deficiency induced hypoprothrombinemia
(vitamin K1) 100 mcg tablet
- Dosage information is not available
(vitamin K1) 5 mg tablet
- 1 tablet (5 mg) by oral route x1 dose; may be repeated in 12 to 48 hours after the first dose
100 mcg tablet
- Dosage information is not available
5 mg tablet
- 1 tablet (5 mg) by oral route x1 dose; may be repeated in 12 to 48 hours after the first dose
5 mg tablet
- 1 tablet (5 mg) by oral route x1 dose; may be repeated in 12 to 48 hours after the first dose
Antibiotic-induced hypoprothrombinemia
- 1 tablet (5 mg) by oral route once
- 2 tablets (10 mg) by oral route once
- 3 tablets (15 mg) by oral route once
- 4 tablets (20 mg) by oral route once
- 5 tablets (25 mg) by oral route once
- one-half tablet (2.5 mg) by oral route once
Anticoagulant-induced prothrombin deficiency
- 1 tablet (5 mg) by oral route x1 dose; may be repeated in 12 to 48 hours after the first dose
- 2 tablets (10 mg) by oral route x1 dose; may be repeated in 12 to 48 hours after the first dose
- 3 tablets (15 mg) by oral route x1 dose; may be repeated in 12 to 48 hours after the first dose
- 4 tablets (20 mg) by oral route x1 dose; may be repeated in 12 to 48 hours after the first dose
- 5 tablets (25 mg) by oral route x1 dose; may be repeated in 12 to 48 hours after the first dose
- one-half tablet (2.5 mg) by oral route x1 dose; may be repeated in 12 to 48 hours after the first dose
Hypoprothrombinemia
- 1 tablet (5 mg) by oral route once
- 2 tablets (10 mg) by oral route once
- 3 tablets (15 mg) by oral route once
- 4 tablets (20 mg) by oral route once
- 5 tablets (25 mg) by oral route once
- one-half tablet (2.5 mg) by oral route once
Vitamin K deficiency induced hypoprothrombinemia
- 1 tablet (5 mg) by oral route once
- 2 tablets (10 mg) by oral route once
- 3 tablets (15 mg) by oral route once
- 4 tablets (20 mg) by oral route once
- 5 tablets (25 mg) by oral route once
- one-half tablet (2.5 mg) by oral route once
- None
Contraindicated
- Coumadin
- Jantoven
- warfarin
Severe
Moderate
- None
- Hemolytic anemia from PK and g6PD deficiencies
Contraindicated
- None
Severe
Moderate
- None
MEPHYTON (PHYTONADIONE)
- Hypoprothrombinemia
- Antibiotic-induced hypoprothrombinemia
- Anticoagulant-induced prothrombin deficiency
- Vitamin K deficiency induced hypoprothrombinemia
- None
- None
More Frequent
Severe
Less Severe
- None
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- None
Less Severe
- Dysgeusia
- Flushing
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Phytonadione (vit K-1)
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Phytonadione
None
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | No adverse effect | None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Antibiotic-induced hypoprothrombinemia | |
| D68.4 | Acquired coagulation factor deficiency |
| Anticoagulant-induced prothrombin deficiency | |
| D68.4 | Acquired coagulation factor deficiency |
| Hypoprothrombinemia | |
| D68.4 | Acquired coagulation factor deficiency |
| Vitamin K deficiency induced hypoprothrombinemia | |
| D68.4 | Acquired coagulation factor deficiency |
| 0-9 | A-Z |
|---|---|
| D68.4 | Acquired coagulation factor deficiency |
| D68.4 | Acquired coagulation factor deficiency |
| D68.4 | Acquired coagulation factor deficiency |
| D68.4 | Acquired coagulation factor deficiency |
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