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SYPRINE (trientine HCl)
- Wilson's disease
250 mg capsule
- 1 capsule (250 mg) by oral route 3 times per day on an empty stomach, 1 hour before or 2 hours after a meal
trientine 250 mg capsule
- 1 capsule (250 mg) by oral route 3 times per day on an empty stomach, 1 hour before or 2 hours after a meal
250 mg capsule
- 1 capsule (250 mg) by oral route 3 times per day on an empty stomach, 1 hour before or 2 hours after a meal
250 mg capsule
- 1 capsule (250 mg) by oral route 3 times per day on an empty stomach, 1 hour before or 2 hours after a meal
Wilson's disease
- 4 capsules (1,000 mg) by oral route 2 times per day on an empty stomach, 1 hour before or 2 hours after a meal
- 1 capsule (250 mg) by oral route 4 times per day on an empty stomach, 1 hour before or 2 hours after a meal
- 1 capsule (250 mg) by oral route 3 times per day on an empty stomach, 1 hour before or 2 hours after a meal
- 2 capsules (500 mg) by oral route 4 times per day on an empty stomach, 1 hour before or 2 hours after a meal
- 2 capsules (500 mg) by oral route 2 times per day on an empty stomach, 1 hour before or 2 hours after a meal
- 2 capsules (500 mg) by oral route 3 times per day on an empty stomach, 1 hour before or 2 hours after a meal
- 3 capsules (750 mg) by oral route 2 times per day on an empty stomach, 1 hour before or 2 hours after a meal
- None
Contraindicated
- None
Severe
Moderate
- None
- None
Contraindicated
- None
Severe
Moderate
- Iron deficiency anemia
SYPRINE (trientine HCl)
- Wilson's disease
- Anemia
- None
More Frequent
Severe
Less Severe
- Systemic lupus erythematosus
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acquired dystonia
- Allergic dermatitis
- Skin rash
- Urticaria
Less Severe
- Muscle spasm
- Muscle weakness
- Pruritus of skin
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Trientine Hydrochloride
Safety and efficacy not established age <12 years. Has been used in children 6+ years.
- 1 Day – 12 Years
- Safety and efficacy not established age <12 years. Has been used in children 6+ years.
Trientine Hydrochloride
- Severity Level:
C
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Trientine Hydrochloride
None
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Wilson's disease | |
| E83.01 | Wilson's disease |
| 0-9 | A-Z |
|---|---|
| E83.01 | Wilson's disease |
Formulary Reference Tool