Please wait while the formulary information is being retrieved.
ZEMBRACE SYMTOUCH (sumatriptan succinate)
- migraine headache
3 mg/0.5 mL subcutaneous pen injector
- Inject 0.5 milliliter (3 mg) by subcutaneous route once; may repeat in 1 hour if pain returns/increases in severity; (max 4 doses/24 hours)
Default screening record
- Inject 0.5 milliliter (3 mg) by subcutaneous route in the outer area of thigh or upper arm once; may be repeated 1 hour after the first dose if headache pain returns or increases in severity; do not exceed 2 doses within 24 hours
- Inject 0.5 milliliter (3 mg) by subcutaneous route once; may repeat in 1 hour if pain returns/increases in severity; (max 2 doses/24 hours)
- Inject 0.5 milliliter (3 mg) by subcutaneous route once; may repeat in 1 hour if pain returns/increases in severity; (max 4 doses/24 hours)
- Inject 0.5 milliliter (3 mg) by subcutaneous route once; may be repeated at least 1 hour after the first dose if headache pain returns or increases in severity; do not exceed 4 doses within 24 hours
- Azilect
- bromocriptine
- Cafergot
- Cycloset
- D.h.e.45
- dihydroergotamine
- Eldepryl
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- isocarboxazid
- linezolid
- Marplan
- Matulane
- methylene blue (antidote)
- methylergonovine
- Migergot
- Migranal
- Nardil
- Parlodel
- Parnate
- phenelzine
- procarbazine
- rasagiline
- selegiline HCl
- tranylcypromine
- Zelapar
- Zyvox
Contraindicated
- None
Severe
Moderate
- None
- Acute myocardial infarction
- Angina
- Cerebral ischemia
- Cerebrovascular accident
- Coronary artery disease
- Hemiplegic migraine
- Ischemic bowel disease
- Myocardial ischemia
- Peripheral vascular disease
- Prinzmetal angina
- Serotonin syndrome
- Severe uncontrolled hypertension
Contraindicated
- None
Severe
Moderate
- Seizure disorder
ZEMBRACE SYMTOUCH (sumatriptan succinate)
- migraine headache
- None
- Dizziness
- Dysgeusia
- Flushing
- Hypoesthesia
- Injection site sequelae
- Nasal passage irritation
- Nausea
- Paresthesia
- Sensation of warmth
- Stinging of skin
- Vertigo
- Vomiting
More Frequent
Severe
Less Severe
- None
- Drowsy
- Dysesthesia
- Hyperhidrosis
- Muscle weakness
- Myalgia
- Neck stiffness
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abdominal pain with cramps
- Acquired dystonia
- Acute myocardial infarction
- Anaphylaxis
- Angioedema
- Bronchospastic pulmonary disease
- Cerebrovascular accident
- Chest pain
- Chest tightness
- Coronary artery spasm
- Dysphagia
- Hypersensitivity drug reaction
- Hypertension
- Hypotension
- Intracerebral hemorrhage
- Ischemic bowel disease
- Myocardial ischemia
- Peripheral ischemia
- Raynaud's phenomenon
- Seizure disorder
- Serotonin syndrome
- Splenic infarction
- Subarachnoid intracranial hemorrhage
- Ventricular fibrillation
- Ventricular tachycardia
- Vision impairment
Less Severe
- Anticholinergic toxicity
- Cramps
- Fatigue
- Jaw pain
- Medication overuse headache
- Mouth irritation
- Muscle rigidity
- Nasal pain
- Palpitations
- Sinusitis
- Sore tongue
- Symptoms of anxiety
- Tremor
- Visual changes
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Sumatriptan
Efficacy not established over placebo for treatment of migraine. Adverse event risk similar to adults including visual loss and stroke.
- 1 Day – 18 Years
- Efficacy not established over placebo for treatment of migraine. Adverse event risk similar to adults including visual loss and stroke.
Sumatriptan
- Severity Level:
2
- Additional Notes: Insufficient human data avail, consider maternal tx benefit vs pot fetal risk
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Sumatriptan (sq)
Low levels excreted; mfr suggests delaying nursing for 12 hours after dose
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Low levels excreted; mfr suggests delaying nursing for 12 hours after dose |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Sumatriptan
Hepatic-Elderly patients are more likely to have decreased hepatic function thus decreasing drug clearance. Cardiovascular-Hypertensive effects may be more pronounced in the elderly and increase the risk for cardiovascular events in those with cardiovascular disease. A cardiovascular evaluation is recommended in those with CV risk factors, Avoid use of the drug in any patient with a cerebrovascular syndrome.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Migraine | |
| G43 | Migraine |
| G43.0 | Migraine without aura |
| G43.00 | Migraine without aura, not intractable |
| G43.001 | Migraine without aura, not intractable, with status migrainosus |
| G43.009 | Migraine without aura, not intractable, without status migrainosus |
| G43.01 | Migraine without aura, intractable |
| G43.011 | Migraine without aura, intractable, with status migrainosus |
| G43.019 | Migraine without aura, intractable, without status migrainosus |
| G43.1 | Migraine with aura |
| G43.10 | Migraine with aura, not intractable |
| G43.101 | Migraine with aura, not intractable, with status migrainosus |
| G43.109 | Migraine with aura, not intractable, without status migrainosus |
| G43.11 | Migraine with aura, intractable |
| G43.111 | Migraine with aura, intractable, with status migrainosus |
| G43.119 | Migraine with aura, intractable, without status migrainosus |
| G43.4 | Hemiplegic migraine |
| G43.40 | Hemiplegic migraine, not intractable |
| G43.41 | Hemiplegic migraine, intractable |
| G43.7 | Chronic migraine without aura |
| G43.70 | Chronic migraine without aura, not intractable |
| G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
| G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
| G43.71 | Chronic migraine without aura, intractable |
| G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
| G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
| G43.8 | Other migraine |
| G43.80 | Other migraine, not intractable |
| G43.801 | Other migraine, not intractable, with status migrainosus |
| G43.809 | Other migraine, not intractable, without status migrainosus |
| G43.81 | Other migraine, intractable |
| G43.811 | Other migraine, intractable, with status migrainosus |
| G43.819 | Other migraine, intractable, without status migrainosus |
| G43.82 | Menstrual migraine, not intractable |
| G43.821 | Menstrual migraine, not intractable, with status migrainosus |
| G43.829 | Menstrual migraine, not intractable, without status migrainosus |
| G43.83 | Menstrual migraine, intractable |
| G43.831 | Menstrual migraine, intractable, with status migrainosus |
| G43.839 | Menstrual migraine, intractable, without status migrainosus |
| G43.9 | Migraine, unspecified |
| G43.90 | Migraine, unspecified, not intractable |
| G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
| G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
| G43.91 | Migraine, unspecified, intractable |
| G43.911 | Migraine, unspecified, intractable, with status migrainosus |
| G43.919 | Migraine, unspecified, intractable, without status migrainosus |
| G43.B | Ophthalmoplegic migraine |
| G43.B0 | Ophthalmoplegic migraine, not intractable |
| G43.B1 | Ophthalmoplegic migraine, intractable |
| G43.C | Periodic headache syndromes in child or adult |
| G43.C0 | Periodic headache syndromes in child or adult, not intractable |
| G43.C1 | Periodic headache syndromes in child or adult, intractable |
| G43.D | Abdominal migraine |
| G43.D0 | Abdominal migraine, not intractable |
| G43.D1 | Abdominal migraine, intractable |
| G43.E | Chronic migraine with aura |
| G43.E0 | Chronic migraine with aura, not intractable |
| G43.E01 | Chronic migraine with aura, not intractable, with status migrainosus |
| G43.E09 | Chronic migraine with aura, not intractable, without status migrainosus |
| G43.E1 | Chronic migraine with aura, intractable |
| G43.E11 | Chronic migraine with aura, intractable, with status migrainosus |
| G43.E19 | Chronic migraine with aura, intractable, without status migrainosus |
| 0-9 | A-Z |
|---|---|
| G43 | Migraine |
| G43.0 | Migraine without aura |
| G43.00 | Migraine without aura, not intractable |
| G43.001 | Migraine without aura, not intractable, with status migrainosus |
| G43.009 | Migraine without aura, not intractable, without status migrainosus |
| G43.01 | Migraine without aura, intractable |
| G43.011 | Migraine without aura, intractable, with status migrainosus |
| G43.019 | Migraine without aura, intractable, without status migrainosus |
| G43.1 | Migraine with aura |
| G43.10 | Migraine with aura, not intractable |
| G43.101 | Migraine with aura, not intractable, with status migrainosus |
| G43.109 | Migraine with aura, not intractable, without status migrainosus |
| G43.11 | Migraine with aura, intractable |
| G43.111 | Migraine with aura, intractable, with status migrainosus |
| G43.119 | Migraine with aura, intractable, without status migrainosus |
| G43.4 | Hemiplegic migraine |
| G43.40 | Hemiplegic migraine, not intractable |
| G43.41 | Hemiplegic migraine, intractable |
| G43.7 | Chronic migraine without aura |
| G43.70 | Chronic migraine without aura, not intractable |
| G43.701 | Chronic migraine without aura, not intractable, with status migrainosus |
| G43.709 | Chronic migraine without aura, not intractable, without status migrainosus |
| G43.71 | Chronic migraine without aura, intractable |
| G43.711 | Chronic migraine without aura, intractable, with status migrainosus |
| G43.719 | Chronic migraine without aura, intractable, without status migrainosus |
| G43.8 | Other migraine |
| G43.80 | Other migraine, not intractable |
| G43.801 | Other migraine, not intractable, with status migrainosus |
| G43.809 | Other migraine, not intractable, without status migrainosus |
| G43.81 | Other migraine, intractable |
| G43.811 | Other migraine, intractable, with status migrainosus |
| G43.819 | Other migraine, intractable, without status migrainosus |
| G43.82 | Menstrual migraine, not intractable |
| G43.821 | Menstrual migraine, not intractable, with status migrainosus |
| G43.829 | Menstrual migraine, not intractable, without status migrainosus |
| G43.83 | Menstrual migraine, intractable |
| G43.831 | Menstrual migraine, intractable, with status migrainosus |
| G43.839 | Menstrual migraine, intractable, without status migrainosus |
| G43.9 | Migraine, unspecified |
| G43.90 | Migraine, unspecified, not intractable |
| G43.901 | Migraine, unspecified, not intractable, with status migrainosus |
| G43.909 | Migraine, unspecified, not intractable, without status migrainosus |
| G43.91 | Migraine, unspecified, intractable |
| G43.911 | Migraine, unspecified, intractable, with status migrainosus |
| G43.919 | Migraine, unspecified, intractable, without status migrainosus |
| G43.B | Ophthalmoplegic migraine |
| G43.B0 | Ophthalmoplegic migraine, not intractable |
| G43.B1 | Ophthalmoplegic migraine, intractable |
| G43.C | Periodic headache syndromes in child or adult |
| G43.C0 | Periodic headache syndromes in child or adult, not intractable |
| G43.C1 | Periodic headache syndromes in child or adult, intractable |
| G43.D | Abdominal migraine |
| G43.D0 | Abdominal migraine, not intractable |
| G43.D1 | Abdominal migraine, intractable |
| G43.E | Chronic migraine with aura |
| G43.E0 | Chronic migraine with aura, not intractable |
| G43.E01 | Chronic migraine with aura, not intractable, with status migrainosus |
| G43.E09 | Chronic migraine with aura, not intractable, without status migrainosus |
| G43.E1 | Chronic migraine with aura, intractable |
| G43.E11 | Chronic migraine with aura, intractable, with status migrainosus |
| G43.E19 | Chronic migraine with aura, intractable, without status migrainosus |
Formulary Reference Tool