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Drug overview for LEVOCARNITINE (levocarnitine (with sugar)):
Generic name: LEVOCARNITINE (WITH SUGAR) (lee-voh-KAR-nih-teen)
Drug class: Levocarnitine
Therapeutic class: Metabolic Modifiers
Amino acid derivative; naturally occurring substance required in mammalian energy metabolism.
No enhanced Uses information available for this drug.
Generic name: LEVOCARNITINE (WITH SUGAR) (lee-voh-KAR-nih-teen)
Drug class: Levocarnitine
Therapeutic class: Metabolic Modifiers
Amino acid derivative; naturally occurring substance required in mammalian energy metabolism.
No enhanced Uses information available for this drug.
DRUG IMAGES
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The following indications for LEVOCARNITINE (levocarnitine (with sugar)) have been approved by the FDA:
Indications:
Carnitine deficiency
Professional Synonyms:
BT factor deficiency
Vitamin BT deficiency
Indications:
Carnitine deficiency
Professional Synonyms:
BT factor deficiency
Vitamin BT deficiency
The following dosing information is available for LEVOCARNITINE (levocarnitine (with sugar)):
Decreasing the dosage of oral levocarnitine may diminish or eliminate drug-related patient body odor or GI symptoms if present.
Administer orally (as a solution or tablets), by direct IV injection, or by IV infusion.
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| LEVOCARNITINE 1 G/10 ML SOLN | Maintenance | Adults take 10 milliliters (1 gram) by oral route 3 times per day with meals |
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| LEVOCARNITINE 1 G/10 ML SOLN | Maintenance | Adults take 10 milliliters (1 gram) by oral route 3 times per day with meals |
| LEVOCARNITINE 500 MG/5 ML CUP | Maintenance | Adults take 10 milliliters (1 gram) by oral route 3 times per day with meals |
| LEVOCARNITINE 1 G/10 ML CUP | Maintenance | Adults take 10 milliliters (1 gram) by oral route 3 times per day with meals |
The following drug interaction information is available for LEVOCARNITINE (levocarnitine (with sugar)):
There are 0 contraindications.
There are 0 severe interactions.
There are 0 moderate interactions.
The following contraindication information is available for LEVOCARNITINE (levocarnitine (with sugar)):
Drug contraindication overview.
Manufacturer states none known.
Manufacturer states none known.
There are 1 contraindications.
Absolute contraindication.
| Contraindication List |
|---|
| Chronic kidney disease stage 5 (failure) GFr<15 ml/min |
There are 0 severe contraindications.
There are 1 moderate contraindications.
Clinically significant contraindication, where the condition can be managed or treated before the drug may be given safely.
| Moderate List |
|---|
| Seizure disorder |
The following adverse reaction information is available for LEVOCARNITINE (levocarnitine (with sugar)):
Adverse reaction overview.
Oral therapy: Transient nausea and vomiting, abdominal cramps, diarrhea, body odor. Parenteral therapy: Transient nausea and vomiting, body odor, gastritis. Patients on chronic hemodialysis may experience injection site reactions, headache, pain, diarrhea, flu syndrome, pharyngitis, infection, hypertension, vomiting, abdominal pain, hypotension, dizziness, increased cough, chest pain, hypercalcemia, accidental injury, asthenia, nausea, fever, anemia, hypervolemia, paresthesia, rhinitis, or dyspnea.
Seizures reported in patients, with or without preexisting seizure activity, receiving either oral or IV levocarnitine. Increased seizure frequency and/or severity also reported in patients with preexisting seizure activity.
Oral therapy: Transient nausea and vomiting, abdominal cramps, diarrhea, body odor. Parenteral therapy: Transient nausea and vomiting, body odor, gastritis. Patients on chronic hemodialysis may experience injection site reactions, headache, pain, diarrhea, flu syndrome, pharyngitis, infection, hypertension, vomiting, abdominal pain, hypotension, dizziness, increased cough, chest pain, hypercalcemia, accidental injury, asthenia, nausea, fever, anemia, hypervolemia, paresthesia, rhinitis, or dyspnea.
Seizures reported in patients, with or without preexisting seizure activity, receiving either oral or IV levocarnitine. Increased seizure frequency and/or severity also reported in patients with preexisting seizure activity.
There are 5 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. | None. |
| Rare/Very Rare |
|---|
|
Anaphylaxis Bronchospastic pulmonary disease Laryngeal edema Muscle weakness Seizure disorder |
There are 9 less severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
|
Abdominal pain with cramps Diarrhea Nausea Vomiting |
Body odor Gastritis |
| Rare/Very Rare |
|---|
|
Facial edema Skin rash Urticaria |
The following precautions are available for LEVOCARNITINE (levocarnitine (with sugar)):
Dosage of levocarnitine in pediatric patients <=18 years of age was based on specific patient case record observations rather than on studies that specifically defined age by protocol.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
Category B.
Distributed into milk in cows; not known whether levocarnitine distributes into human milk. Consider discontinuance of nursing or the drug.
No enhanced Geriatric Use information available for this drug.
The following prioritized warning is available for LEVOCARNITINE (levocarnitine (with sugar)):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for LEVOCARNITINE (levocarnitine (with sugar))'s list of indications:
| Carnitine deficiency | |
| E71.4 | Disorders of carnitine metabolism |
| E71.40 | Disorder of carnitine metabolism, unspecified |
| E71.41 | Primary carnitine deficiency |
| E71.42 | Carnitine deficiency due to inborn errors of metabolism |
| E71.43 | Iatrogenic carnitine deficiency |
| E71.44 | Other secondary carnitine deficiency |
| E71.448 | Other secondary carnitine deficiency |
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