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TORSEMIDE (torsemide)
- Edema
- Hypertension
- Edema due to hepatic cirrhosis
- Peripheral edema due to chronic heart failure
- Pulmonary edema due to chronic heart failure
- Renal disease with edema
10 mg tablet
- 1 tablet (10 mg) by oral route once daily
100 mg tablet
- 1 tablet (100 mg) by oral route once daily
20 mg tablet
- 1 tablet (20 mg) by oral route once daily
5 mg tablet
- 2 tablets (10 mg) by oral route once daily
Edema
- 2 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route once daily
- 2 tablets (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route once daily
- 2 tablets (40 mg) by oral route once daily
- 1 tablet (100 mg) by oral route once daily
- 2 tablets (200 mg) by oral route once daily
Edema due to hepatic cirrhosis
- 1 tablet (5 mg) by oral route once daily
- 2 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route once daily
- 2 tablets (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route once daily
- 2 tablets (40 mg) by oral route once daily
Hypertension
- 1 tablet (5 mg) by oral route once daily
- 2 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route once daily
Peripheral edema due to chronic heart failure
- 2 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route once daily
- 2 tablets (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route once daily
- 2 tablets (40 mg) by oral route once daily
- 1 tablet (100 mg) by oral route once daily
- 2 tablets (200 mg) by oral route once daily
Pulmonary edema due to chronic heart failure
- 2 tablets (10 mg) by oral route once daily
- 1 tablet (10 mg) by oral route once daily
- 2 tablets (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route once daily
- 2 tablets (40 mg) by oral route once daily
- 1 tablet (100 mg) by oral route once daily
- 2 tablets (200 mg) by oral route once daily
Renal disease with edema
- 2 tablets (20 mg) by oral route once daily
- 1 tablet (20 mg) by oral route once daily
- 2 tablets (40 mg) by oral route once daily
- 1 tablet (100 mg) by oral route once daily
- 2 tablets (200 mg) by oral route once daily
- None
Contraindicated
- Curad Enema
- Disposable Enema
- Enema
- Enema Disposable
- Fleet Enema
- Fleet Enema Extra
- Fleet Pediatric
- lithium carbonate
- lithium citrate
- Lithobid
- Oral Saline Laxative
- Osmoprep
- Phosphate Laxative
- Preparation Cleansing
- Ready-to-use Enema
- Reclast
- sod phos mono-sod phos dibasic
- sodium phosphates
- zoledronic acid
- zoledronic acid-mannitol-water
- Zometa
Severe
Moderate
- Accupril
- Accuretic
- Aceon
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- Altace
- amikacin
- amlodipine-benazepril
- amlodipine-olmesartan
- amlodipine-valsartan
- amlodipine-valsartan-hcthiazid
- Anaprox
- Anaprox Ds
- Ansaid
- Arthrotec 50
- Atacand
- Atacand Hct
- Avalide
- Avapro
- azilsartan med-chlorthalidone
- azilsartan medoxomil
- Azor
- benazepril
- benazepril-hydrochlorothiazide
- Benicar
- Benicar Hct
- Caldolor
- Cambia
- candesartan
- candesartan-hydrochlorothiazid
- captopril
- captopril-hydrochlorothiazide
- Cataflam
- Celebrex
- celecoxib
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- Coly-mycin S
- Cortisporin
- Cortisporin-tc
- Cozaar
- Daypro
- diclofenac epolamine
- diclofenac potassium
- diclofenac sodium
- diclofenac submicronized
- diclofenac-misoprostol
- Digox
- digoxin
- Diovan Hct
- Duexis
- Ec-naprosyn
- Edarbi
- Edarbyclor
- enalapril maleate
- enalapril-hydrochlorothiazide
- enalaprilat
- Epaned
- eprosartan
- eprosartan-hydrochlorothiazide
- etodolac
- Exforge
- Exforge Hct
- Feldene
- fenoprofen
- Flanax
- Flector
- flurbiprofen
- fosinopril
- fosinopril-hydrochlorothiazide
- gentamicin
- gentamicin in NaCl (iso-osm)
- gentamicin sulfate (ped) (PF)
- gentamicin sulfate (PF)
- hydrocodone-ibuprofen
- Hyzaar
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Indocin
- indomethacin
- indomethacin sodium
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- irbesartan
- irbesartan-hydrochlorothiazide
- ketoprofen
- ketorolac
- Lanoxin
- Lanoxin Pediatric
- lisinopril
- lisinopril-hydrochlorothiazide
- losartan
- losartan-hydrochlorothiazide
- Lotensin
- Lotrel
- Mavik
- Medi-profen
- Mediproxen
- mefenamic acid
- meloxicam
- Micardis
- Micardis Hct
- Midol (naproxen)
- Mobic
- moexipril
- moexipril-hydrochlorothiazide
- Motrin Ib
- Motrin Pm
- nabumetone
- Nalfon
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- neomycin
- neomycin-colist-HC-thonzonium
- neomycin-polymyxin-HC
- Neoprofen (ibuprofen Lysn)(pf)
- olmesartan
- olmesartan-amlodipin-hcthiazid
- olmesartan-hydrochlorothiazide
- oxaprozin
- Pennsaid
- perindopril erbumine
- piroxicam
- Ponstel
- Prinivil
- Provil
- pseudoephedrine-ibuprofen
- quinapril
- quinapril-hydrochlorothiazide
- ramipril
- Reprexain
- Sinus & Cold-d
- Solaraze
- Sprix
- streptomycin
- sulindac
- Tarka
- telmisartan
- telmisartan-amlodipine
- telmisartan-hydrochlorothiazid
- Teveten
- Teveten Hct
- tobramycin in 0.9 % NaCl
- tobramycin sulfate
- tolmetin
- trandolapril
- trandolapril-verapamil
- Tribenzor
- Twynsta
- Uniretic
- Univasc
- valsartan-hydrochlorothiazide
- Vaseretic
- Vasotec
- Vicoprofen
- Vimovo
- Voltaren-xr
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- Zestoretic
- Zestril
- Zipsor
- Zorvolex
- Anuria
Contraindicated
- Ascites
- Azotemia
- Dehydration
- Hepatic cirrhosis
- Hypokalemia
- Hypovolemia
- Metabolic alkalosis
Severe
Moderate
- Gout
- Hearing loss
- Hypertriglyceridemia
- Hyperuricemia
TORSEMIDE (torsemide)
- Edema
- Hypertension
- Edema due to hepatic cirrhosis
- Peripheral edema due to chronic heart failure
- Pulmonary edema due to chronic heart failure
- Renal disease with edema
- None
- Polyuria
More Frequent
Severe
Less Severe
- Abnormal ECG
- Hypocalcemia
- Hypochloremic alkalosis
- Hypokalemia
- Hypomagnesemia
- Hyponatremia
- Hypercholesterolemia
- Hypertriglyceridemia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acute renal failure
- Anemia
- Hearing loss
- Hypotension
- Kidney disease with reduction in GFR
- Leukopenia
- Ototoxicity
- Pancreatitis
- Stevens-johnson syndrome
- Thiamine deficiency
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
Less Severe
- Acute abdominal pain
- Acute confusion
- Anorexia
- Hyperglycemia
- Hyperuricemia
- Paresthesia
- Phototoxicity
- Pruritus of skin
- Skin rash
- Tinnitus
- Visual changes
Contraindicated
None
Severe Precaution
Torsemide
Potential risk of nephrocalcinosis/nephrolithiasis with continued use. Safety and efficacy not established.
- 1 Day – 4 Years
- Potential risk of nephrocalcinosis/nephrolithiasis with continued use. Safety and efficacy not established.
Management or Monitoring Precaution
Torsemide
Safety and efficacy not established.
- 4 Years – 18 Years
- Safety and efficacy not established.
Torsemide
- Severity Level:
2
- Additional Notes: Insufficient human data; animal data sug dev tox <10 x mrhd
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Torsemide
Insufficient data available.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Torsemide
Cardiovascular-Elderly are more sensitive to hypotensive effects. Avoid over diuresis. Metabolic-Elderly are more sensitive to drug induced electrolyte loss. Monitor serum potassium, magnesium, and sodium.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | Y | Y | N | N | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- None
| Edema | |
| R60 | Edema, not elsewhere classified |
| R60.0 | Localized edema |
| R60.1 | Generalized edema |
| R60.9 | Edema, unspecified |
| Edema due to hepatic cirrhosis | |
| K70.11 | Alcoholic hepatitis with ascites |
| K70.31 | Alcoholic cirrhosis of liver with ascites |
| K71.51 | Toxic liver disease with chronic active hepatitis with ascites |
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| Peripheral edema due to chronic heart failure | |
| R60 | Edema, not elsewhere classified |
| R60.9 | Edema, unspecified |
| Pulmonary edema due to chronic heart failure | |
| J81.0 | Acute pulmonary edema |
| Renal disease with edema | |
| R60.1 | Generalized edema |
| R60.9 | Edema, unspecified |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| J81.0 | Acute pulmonary edema |
| K70.11 | Alcoholic hepatitis with ascites |
| K70.31 | Alcoholic cirrhosis of liver with ascites |
| K71.51 | Toxic liver disease with chronic active hepatitis with ascites |
| R60 | Edema, not elsewhere classified |
| R60 | Edema, not elsewhere classified |
| R60.0 | Localized edema |
| R60.1 | Generalized edema |
| R60.1 | Generalized edema |
| R60.9 | Edema, unspecified |
| R60.9 | Edema, unspecified |
| R60.9 | Edema, unspecified |
Formulary Reference Tool