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ZANOSAR (STREPTOZOCIN)
- Pancreatic neuroendocrine tumor
1 gram intravenous solution
- Dosage information is not available
1 gram intravenous solution
- Dosage information is not available
Carcinoid syndrome
- Infuse 500 mg/m2 by intravenous route once daily for 5 days
- Infuse 1,000 mg/m2 by intravenous route once weekly
- Infuse 1,500 mg/m2 by intravenous route once weekly
Pancreatic neuroendocrine tumor
- Infuse 500 mg/m2 by intravenous route once daily for 5 days
- Infuse 1,000 mg/m2 by intravenous route once weekly
- Infuse 1,500 mg/m2 by intravenous route once weekly
- adenovirus vac live type-4 & 7
- adenovirus vaccine live type-4
- adenovirus vaccine live type-7
- BCG vaccine, live (PF)
- cidofovir
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- M-m-r Ii (pf)
- measles,mumps&rubella vacc(PF)
- measles,mumps,rub,varicel(PF)
- natalizumab
- Proquad (pf)
- Rotateq Vaccine
- rotavirus vaccine live, penta
- typhoid vaccine
- Tysabri
- varicella virus vacc live (PF)
- Varivax (pf)
- Vistide
- Vivotif Berna Vaccine
- yellow fever vaccine live (PF)
- Yf-vax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
Contraindicated
- None
Severe
Moderate
- adefovir
- Atripla
- Complera
- efavirenz-emtricitabin-tenofov
- elvitegr-cobicist-emtric-tenof
- emtricitab-rilpivirine-tenofov
- emtricitabine-tenofovir
- Hepsera
- Stribild
- tenofovir disoproxil fumarate
- Truvada
- Viread
- Lactating mother
Contraindicated
- Anemia
- Bacterial infection
- Disease of liver
- Increased risk of bleeding due to coagulation disorder
- Infection
- Kidney disease with likely reduction in GFR
- Leukopenia
- Opportunistic fungal infection
- Opportunistic viral infection
- Pregnancy
- Protozoal infection
- Thrombocytopenic disorder
Severe
Moderate
- Bone marrow depression
- Diabetes mellitus
ZANOSAR (STREPTOZOCIN)
- Pancreatic neuroendocrine tumor
- Kidney disease with reduction in GFR
- Renal failure
- Nausea
- Vomiting
More Frequent
Severe
Less Severe
- Hypoglycemic disorder
- Injection site sequelae
- Diarrhea
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Drug-induced hepatitis
- Infection
- Jaundice
- Leukopenia
- Thrombocytopenic disorder
Less Severe
- None
Contraindicated
None
Severe Precaution
Streptozocin
No safety and efficacy data available for use in pediatrics.
- 1 Day – 18 Years
- No safety and efficacy data available for use in pediatrics.
Management or Monitoring Precaution
None
Streptozocin
- Severity Level:
D
- Additional Notes:
Contraindicated
Streptozocin
Potential serious adv eff on infant;Moleculr wt low enough for poss excretion
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Potential serious adv eff on infant;Moleculr wt low enough for poss excretion |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Streptozocin
Renal-High incidence of nephrotoxicity. Use caution in patients with pre-existing renal impairment.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Pancreatic neuroendocrine tumor | |
| C25.4 | Malignant neoplasm of endocrine pancreas |
| 0-9 | A-Z |
|---|---|
| C25.4 | Malignant neoplasm of endocrine pancreas |
Formulary Reference Tool