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INCRELEX (MECASERMIN)
- Primary insulin-like growth factor-1 deficiency
10 mg/mL subcutaneous solution
- Dosage information is not available
10 mg/mL subcutaneous solution
- Dosage information is not available
- None
Contraindicated
- None
Severe
Moderate
- None
- Malignancy
Contraindicated
- Sleep apnea
Severe
Moderate
- Hypertrophy of tonsils
- Hypoglycemic disorder
- Intracranial hypertension
- Papilledema
- Scoliosis
- Slipped capital epiphyses
INCRELEX (MECASERMIN)
- Primary insulin-like growth factor-1 deficiency
- Acute bacterial otitis media
- Anemia
- Bruising
- Hyperglycemia
- Hypoglycemic disorder
- Injection site sequelae
- Lymphadenopathy
- Bone pain
- Lipodystrophy
More Frequent
Severe
Less Severe
- Abnormal hepatic function tests
- Erythema
- Hearing loss
- Hematuria
- Intracranial hypertension
- Ovarian cyst
- Arthralgias
- Dizziness
- Earache
- Foot pain
- Headache disorder
- Pruritus of skin
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Angioedema
- Avascular necrosis of bone
- Dyspnea
- Seizure disorder
- Slipped capital epiphyses
- Urticaria
Less Severe
- Abnormal hair texture
- Alopecia
- Hypertrophy of tonsils
- Papilledema
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Mecasermin
No safety and efficacy age < 2 years.
- 1 Day – 2 Years
- No safety and efficacy age < 2 years.
Mecasermin
- Severity Level:
2
- Additional Notes: Insufficient human data
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Mecasermin
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Primary insulin-like growth factor-1 deficiency | |
| E34.3 | Short stature due to endocrine disorder |
| 0-9 | A-Z |
|---|---|
| E34.3 | Short stature due to endocrine disorder |
Formulary Reference Tool