LONSURF (TRIFLURIDINE/TIPIRACIL HCL)

15 mg-6.14 mg tablet

• 35 mg/m2 by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle max 80 mg/dose based on trifluridine

20 mg-8.19 mg tablet

• 35 mg/m2 by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle max 80 mg/dose based on trifluridine

Metastatic colorectal cancer

• 35 mg/m2 by oral route 2 times per day on days 1 through 5 of a 28 day cycle max of 80 mg/dose based on trifluridine component

• 35 mg/m2 by oral route 2 times per day on days 8 through 12 of a28 day cycle max of 80 mg/dose based on trifluridine component

• 35 mg/m2 by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle max 80 mg/dose based on trifluridine

• 3 tablets by oral route 2 times per day on days 1 through 5 of a28 day cycle

• 3 tablets by oral route 2 times per day on days 8 through 12 of a 28 day cycle

• 3 tablets by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle

• 4 tablets by oral route 2 times per day on days 1 through 5 of a28 day cycle

• 4 tablets by oral route 2 times per day on days 8 through 12 of a 28 day cycle

• 4 tablets by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle

• 2 tablets by oral route 2 times per day on days 1 through 5 of a28 day cycle

• 2 tablets by oral route 2 times per day on days 8 through 12 of a 28 day cycle

• 2 tablets by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle

Metastatic gastric cancer

• 35 mg/m2 by oral route 2 times per day on days 1 through 5 of a 28 day cycle max of 80 mg/dose based on trifluridine component

• 35 mg/m2 by oral route 2 times per day on days 8 through 12 of a28 day cycle max of 80 mg/dose based on trifluridine component

• 35 mg/m2 by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle max 80 mg/dose based on trifluridine

• 3 tablets by oral route 2 times per day on days 1 through 5 of a28 day cycle

• 3 tablets by oral route 2 times per day on days 8 through 12 of a 28 day cycle

• 3 tablets by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle

• 4 tablets by oral route 2 times per day on days 1 through 5 of a28 day cycle

• 4 tablets by oral route 2 times per day on days 8 through 12 of a 28 day cycle

• 4 tablets by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle

• 2 tablets by oral route 2 times per day on days 1 through 5 of a28 day cycle

• 2 tablets by oral route 2 times per day on days 8 through 12 of a 28 day cycle

• 2 tablets by oral route 2 times per day on days 1 through 5 and days 8 through 12 of a 28 day cycle