NITE TIME (DEXTROMETHORPHAN HBR/P-EPHED HCL/ACETAMINOPHEN/DOXYLAMINE)

Contraindicated



• Azilect
• Eldepryl
• isocarboxazid
• linezolid
• Marplan
• Matulane
• methylene blue (antidote)
• Nardil
• Parnate
• phenelzine
• procarbazine
• rasagiline
• selegiline HCl
• tranylcypromine
• Zelapar
• Zyvox

Severe



• bromocriptine
• cabergoline
• Cafergot
• Cycloset
• D.h.e.45
• dihydroergotamine
• ergoloid
• Ergomar
• ergotamine tartrate
• ergotamine-caffeine
• methylergonovine
• Migergot
• Migranal
• Parlodel

Contraindicated



• Acetaminophen overdose
• Acute hepatic failure
• Acute hepatitis C
• Angle-closure glaucoma
• Severe coronary artery disease
• Severe uncontrolled hypertension
• Urinary retention

Severe



• Angle-closure glaucoma
• Benign prostatic hyperplasia
• Bladder outflow obstruction
• Chronic idiopathic constipation
• Diabetes mellitus
• Disease of liver
• Hypertension
• Hyperthyroidism
• Protein-calorie malnutrition
• Severe renal impairment
• Shock
• Stenosing peptic ulcer
• Systemic mastocytosis
• Urinary retention

Contraindicated

Dextromethorphan (OTC)

Do not use in pediatrics <6 years of age unless clinician consultation.

CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

High risk of adverse CNS effects. Not recommended for use age < 6 years.

• 1 Day – 6 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.
• 1 Day – 2 Years
• 1 Do not use in pediatrics <6 years of age unless clinician consultation.

Doxylamine

Do not use in pediatrics <6 years of age unless clinician consultation.

CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

High risk of adverse CNS effects. Not recommended for use age < 6 years.

• 1 Day – 6 Years
• 1 CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.
• 1 Day – 2 Years
• 1 CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

Pseudoephedrine (Immed. Release)

Do not use in pediatrics <6 years of age unless clinician consultation.

CNS excitation and convulsion risk in newborns. Avoid use with age <2 years.

High risk of adverse CNS effects. Not recommended for use age < 6 years.

• 1 Day – 6 Years
• 1 High risk of adverse CNS effects. Not recommended for use age < 6 years.
• 1 Day – 2 Years
• 1 High risk of adverse CNS effects. Not recommended for use age < 6 years.

Severe Precaution

Doxylamine

CNS and respiratory depression, or excitation. Avoid using with underlying asthma. Consult clinician for use in patient age < 6 years.

• 2 Years – 6 Years
• CNS and respiratory depression, or excitation. Avoid using with underlying asthma. Consult clinician for use in patient age < 6 years.

Management or Monitoring Precaution

Acetaminophen (oral,rectal)

Use weight based dosing in children less than 12 years.

• 1 Day – 12 Years
• Use weight based dosing in children less than 12 years.