Please wait while the formulary information is being retrieved.
ODOMZO (SONIDEGIB PHOSPHATE)
- Basal cell carcinoma of skin
200 mg capsule
- 1 capsule (200 mg) by oral route once daily
Basal cell carcinoma of skin
- 1 capsule (200 mg) by oral route once daily
- None
Contraindicated
- Atripla
- B cplx-C-St.Johnwrt-K.&S.ginsg
- Belladonna-phenobarbital
- bosentan
- calcium-mag-B complex-D3-hrb61
- carbamazepine
- Carbatrol
- Cerebyx
- Cold & Flu Fighter
- dabrafenib
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Donnatal
- efavirenz
- efavirenz-emtricitabin-tenofov
- enzalutamide
- Epitol
- Equetro
- etravirine
- Fatigue Relief Complex
- fosphenytoin
- Intelence
- isoniazid-rifamp-pyrazinamide
- Luminal
- modafinil
- Mysoline
- nafcillin
- nafcillin in dextrose iso-osm
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- Priftin
- primidone
- Provigil
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- rifapentine
- Rifater
- St. John's wort
- Sustiva
- Tafinlar
- Tegretol
- Tegretol Xr
- Tracleer
- vit C-St. John wort-elder-hb30
- Women's Complex
- Xtandi
Severe
Moderate
- None
- Lactating mother
Contraindicated
- Myalgias
- Myopathy with CK elevation
- Pregnancy
Severe
Moderate
- None
ODOMZO (SONIDEGIB PHOSPHATE)
- Basal cell carcinoma of skin
- None
- Acute abdominal pain
- Alopecia
- Anemia
- Anorexia
- Diarrhea
- Dysgeusia
- Fatigue
- Headache disorder
- Lymphopenia
- Muscle spasm
- Musculoskeletal pain
- Myalgias
- Nausea
- Pruritus of skin
- Vomiting
- Weight loss
More Frequent
Severe
Less Severe
- None
- General weakness
- Pain
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Rhabdomyolysis
Less Severe
- Amenorrhea
Contraindicated
None
Severe Precaution
Sonidegib
Potential risk of skeletal and growth abnormalities. Premature fusion of the epiphyses reported. No safety and efficacy.
- 1 Day – 18 Years
- Potential risk of skeletal and growth abnormalities. Premature fusion of the epiphyses reported. No safety and efficacy.
Management or Monitoring Precaution
None
Sonidegib
- Severity Level:
D
- Additional Notes: Based on pharmacology may cause fetal harm
Contraindicated
Sonidegib
Insuff data avail; mfr rec avoid bfeeding during and for 20 mo after tx
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Insuff data avail; mfr rec avoid bfeeding during and for 20 mo after tx |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Sonidegib
General-There was a higher incidence of serious adverse events, Grades 3 and 4, and events requiring dose interruption or discontinuation in patients >65 years compared with younger patients; this was not attributable to an increase in any specific adverse event.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | N | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- Sonidegib is not recommended for use during pregnancy because it may cause serious harm (possibly death) to an unborn baby. Women of childbearing age must have a pregnancy test before starting this medication. They must also use reliable forms of birth control while taking sonidegib and for 20 months after the last dose of this medication.<br /><br /> It is unknown if sonidegib passes into semen. Because of the possible risk of passing the drug on to a partner, men taking sonidegib (including men who have had a vasectomy) must use condoms during sex with women who are pregnant or of childbearing age, both during treatment with sonidegib and for 8 months after the last dose of this medication. Men should also not donate sperm during this time. If you or your partner become pregnant or think you may be pregnant, tell your doctor right away.
| Basal cell carcinoma of skin | |
| C44.01 | Basal cell carcinoma of skin of lip |
| C44.11 | Basal cell carcinoma of skin of eyelid, including canthus |
| C44.111 | Basal cell carcinoma of skin of unspecified eyelid, including canthus |
| C44.112 | Basal cell carcinoma of skin of right eyelid, including canthus |
| C44.1121 | Basal cell carcinoma of skin of right upper eyelid, including canthus |
| C44.1122 | Basal cell carcinoma of skin of right lower eyelid, including canthus |
| C44.119 | Basal cell carcinoma of skin of left eyelid, including canthus |
| C44.1191 | Basal cell carcinoma of skin of left upper eyelid, including canthus |
| C44.1192 | Basal cell carcinoma of skin of left lower eyelid, including canthus |
| C44.21 | Basal cell carcinoma of skin of ear and external auricular canal |
| C44.211 | Basal cell carcinoma of skin of unspecified ear and external auricular canal |
| C44.212 | Basal cell carcinoma of skin of right ear and external auricular canal |
| C44.219 | Basal cell carcinoma of skin of left ear and external auricular canal |
| C44.31 | Basal cell carcinoma of skin of other and unspecified parts of face |
| C44.310 | Basal cell carcinoma of skin of unspecified parts of face |
| C44.311 | Basal cell carcinoma of skin of nose |
| C44.319 | Basal cell carcinoma of skin of other parts of face |
| C44.41 | Basal cell carcinoma of skin of scalp and neck |
| C44.51 | Basal cell carcinoma of skin of trunk |
| C44.510 | Basal cell carcinoma of anal skin |
| C44.511 | Basal cell carcinoma of skin of breast |
| C44.519 | Basal cell carcinoma of skin of other part of trunk |
| C44.61 | Basal cell carcinoma of skin of upper limb, including shoulder |
| C44.611 | Basal cell carcinoma of skin of unspecified upper limb, including shoulder |
| C44.612 | Basal cell carcinoma of skin of right upper limb, including shoulder |
| C44.619 | Basal cell carcinoma of skin of left upper limb, including shoulder |
| C44.71 | Basal cell carcinoma of skin of lower limb, including hip |
| C44.711 | Basal cell carcinoma of skin of unspecified lower limb, including hip |
| C44.712 | Basal cell carcinoma of skin of right lower limb, including hip |
| C44.719 | Basal cell carcinoma of skin of left lower limb, including hip |
| C44.81 | Basal cell carcinoma of overlapping sites of skin |
| C44.91 | Basal cell carcinoma of skin, unspecified |
| 0-9 | A-Z |
|---|---|
| C44.01 | Basal cell carcinoma of skin of lip |
| C44.11 | Basal cell carcinoma of skin of eyelid, including canthus |
| C44.111 | Basal cell carcinoma of skin of unspecified eyelid, including canthus |
| C44.112 | Basal cell carcinoma of skin of right eyelid, including canthus |
| C44.1121 | Basal cell carcinoma of skin of right upper eyelid, including canthus |
| C44.1122 | Basal cell carcinoma of skin of right lower eyelid, including canthus |
| C44.119 | Basal cell carcinoma of skin of left eyelid, including canthus |
| C44.1191 | Basal cell carcinoma of skin of left upper eyelid, including canthus |
| C44.1192 | Basal cell carcinoma of skin of left lower eyelid, including canthus |
| C44.21 | Basal cell carcinoma of skin of ear and external auricular canal |
| C44.211 | Basal cell carcinoma of skin of unspecified ear and external auricular canal |
| C44.212 | Basal cell carcinoma of skin of right ear and external auricular canal |
| C44.219 | Basal cell carcinoma of skin of left ear and external auricular canal |
| C44.31 | Basal cell carcinoma of skin of other and unspecified parts of face |
| C44.310 | Basal cell carcinoma of skin of unspecified parts of face |
| C44.311 | Basal cell carcinoma of skin of nose |
| C44.319 | Basal cell carcinoma of skin of other parts of face |
| C44.41 | Basal cell carcinoma of skin of scalp and neck |
| C44.51 | Basal cell carcinoma of skin of trunk |
| C44.510 | Basal cell carcinoma of anal skin |
| C44.511 | Basal cell carcinoma of skin of breast |
| C44.519 | Basal cell carcinoma of skin of other part of trunk |
| C44.61 | Basal cell carcinoma of skin of upper limb, including shoulder |
| C44.611 | Basal cell carcinoma of skin of unspecified upper limb, including shoulder |
| C44.612 | Basal cell carcinoma of skin of right upper limb, including shoulder |
| C44.619 | Basal cell carcinoma of skin of left upper limb, including shoulder |
| C44.71 | Basal cell carcinoma of skin of lower limb, including hip |
| C44.711 | Basal cell carcinoma of skin of unspecified lower limb, including hip |
| C44.712 | Basal cell carcinoma of skin of right lower limb, including hip |
| C44.719 | Basal cell carcinoma of skin of left lower limb, including hip |
| C44.81 | Basal cell carcinoma of overlapping sites of skin |
| C44.91 | Basal cell carcinoma of skin, unspecified |
Formulary Reference Tool