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SYNVEXIA TC (LIDOCAINE HCL/MENTHOL)
- Minor skin wound pain
- Pruritus of skin
- Skin irritation
4 %-1 % topical cream
- Apply a thin layer to the affected area(s) by topical route 2-3 timesdaily
(lidocaine HCl-menthol) 4 %-1 % topical cream
- Apply a thin layer to the affected area(s) by topical route 2-3 timesdaily
Minor skin wound pain
- Apply a thin layer to the affected area(s) by topical route 2 times per day
- Apply a thin layer to the affected area(s) by topical route 3 times per day
- Apply a thin layer to the affected area(s) by topical route 2-3 timesdaily
Pruritus of skin
- Apply a thin layer to the affected area(s) by topical route 2 times per day
- Apply a thin layer to the affected area(s) by topical route 3 times per day
- Apply a thin layer to the affected area(s) by topical route 2-3 timesdaily
Skin irritation
- Apply a thin layer to the affected area(s) by topical route 2 times per day
- Apply a thin layer to the affected area(s) by topical route 3 times per day
- Apply a thin layer to the affected area(s) by topical route 2-3 timesdaily
- None
Contraindicated
- None
Severe
Moderate
- None
- Large open wound
- Methemoglobinemia
Contraindicated
- Burns
- Glucose-6-phosphate dehydrogenase (g6Pd) deficiency
- Heart block
- Hemolytic anemia from PK and g6PD deficiencies
- Sepsis
- Shock
Severe
Moderate
- Disease of liver
- Respiratory depression
- Seizure disorder
SYNVEXIA TC (LIDOCAINE HCL/MENTHOL)
- Minor skin wound pain
- Pruritus of skin
- Skin irritation
- None
- None
More Frequent
Severe
Less Severe
- Angioedema
- Dermatitis due to topical drug
- Erythema
- Pruritus of skin
- Skin rash
- Stinging of skin
- Urticaria
- Stinging of skin
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute respiratory insufficiency
- Anaphylaxis
- Bradycardia
- Burns
- Cardiac arrhythmia
- CNS toxicity
- Cyanosis
- Drowsy
- Eyelid edema
- Headache disorder
- Hypotension
- Methemoglobinemia
- Respiratory depression
- Seizure disorder
- Tremor
- Unconsciousness
Less Severe
- Acute confusion
- Apprehension
- Blurred vision
- Dizziness
- Edema
- Euphoria
- Nervousness
- Sensation of cold
- Sensation of warmth
- Tinnitus
- Twitching
- Vomiting
Contraindicated
None
Severe Precaution
Lidocaine (Top)
Rare risk of methemoglobinemia in infants age < 6 months. Use dose based on age, body weight and physical condition.
- 1 Day – 179 Days
- Rare risk of methemoglobinemia in infants age < 6 months. Use dose based on age, body weight and physical condition.
Management or Monitoring Precaution
Lidocaine (Top)
Rare risk of methemoglobinemia. Use dose based on age, body weight and physical condition.
- 180 Days – 13 Years
- Rare risk of methemoglobinemia. Use dose based on age, body weight and physical condition.
Lidocaine
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Lidocaine
Amount excreted reported to be low with low infant oral bioavailability
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | Not known; no or inclusive data | Amount excreted reported to be low with low infant oral bioavailability |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Pruritus of skin | |
| L29.8 | Other pruritus |
| L29.9 | Pruritus, unspecified |
| Skin irritation | |
| L24 | Irritant contact dermatitis |
| L24.0 | Irritant contact dermatitis due to detergents |
| L24.1 | Irritant contact dermatitis due to oils and greases |
| L24.2 | Irritant contact dermatitis due to solvents |
| L24.3 | Irritant contact dermatitis due to cosmetics |
| L24.4 | Irritant contact dermatitis due to drugs in contact with skin |
| L24.5 | Irritant contact dermatitis due to other chemical products |
| L24.6 | Irritant contact dermatitis due to food in contact with skin |
| L24.7 | Irritant contact dermatitis due to plants, except food |
| L24.8 | Irritant contact dermatitis due to other agents |
| L24.81 | Irritant contact dermatitis due to metals |
| L24.89 | Irritant contact dermatitis due to other agents |
| L24.9 | Irritant contact dermatitis, unspecified cause |
| L25 | Unspecified contact dermatitis |
| L25.0 | Unspecified contact dermatitis due to cosmetics |
| L25.1 | Unspecified contact dermatitis due to drugs in contact with skin |
| L25.2 | Unspecified contact dermatitis due to dyes |
| L25.3 | Unspecified contact dermatitis due to other chemical products |
| L25.4 | Unspecified contact dermatitis due to food in contact with skin |
| L25.5 | Unspecified contact dermatitis due to plants, except food |
| L25.8 | Unspecified contact dermatitis due to other agents |
| L25.9 | Unspecified contact dermatitis, unspecified cause |
| L30.9 | Dermatitis, unspecified |
| R21 | Rash and other nonspecific skin eruption |
| 0-9 | A-Z |
|---|---|
| L24 | Irritant contact dermatitis |
| L24.0 | Irritant contact dermatitis due to detergents |
| L24.1 | Irritant contact dermatitis due to oils and greases |
| L24.2 | Irritant contact dermatitis due to solvents |
| L24.3 | Irritant contact dermatitis due to cosmetics |
| L24.4 | Irritant contact dermatitis due to drugs in contact with skin |
| L24.5 | Irritant contact dermatitis due to other chemical products |
| L24.6 | Irritant contact dermatitis due to food in contact with skin |
| L24.7 | Irritant contact dermatitis due to plants, except food |
| L24.8 | Irritant contact dermatitis due to other agents |
| L24.81 | Irritant contact dermatitis due to metals |
| L24.89 | Irritant contact dermatitis due to other agents |
| L24.9 | Irritant contact dermatitis, unspecified cause |
| L25 | Unspecified contact dermatitis |
| L25.0 | Unspecified contact dermatitis due to cosmetics |
| L25.1 | Unspecified contact dermatitis due to drugs in contact with skin |
| L25.2 | Unspecified contact dermatitis due to dyes |
| L25.3 | Unspecified contact dermatitis due to other chemical products |
| L25.4 | Unspecified contact dermatitis due to food in contact with skin |
| L25.5 | Unspecified contact dermatitis due to plants, except food |
| L25.8 | Unspecified contact dermatitis due to other agents |
| L25.9 | Unspecified contact dermatitis, unspecified cause |
| L29.8 | Other pruritus |
| L29.9 | Pruritus, unspecified |
| L30.9 | Dermatitis, unspecified |
| R21 | Rash and other nonspecific skin eruption |
Formulary Reference Tool