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SULAR (NISOLDIPINE)
- Hypertension
17 mg tablet,extended release
- 1 tablet (17 mg) by oral route once daily
34 mg tablet,extended release
- 1 tablet (34 mg) by oral route once daily
8.5 mg tablet,extended release
- 1 tablet (8.5 mg) by oral route once daily
ER 17 mg tablet,extended release 24 hr
- 1 tablet (17 mg) by oral route once daily
ER 20 mg tablet,extended release 24 hr
- 1 tablet (20 mg) by oral route once daily
ER 25.5 mg tablet,extended release 24 hr
- 1 tablet (25.5 mg) by oral route once daily
ER 30 mg tablet,extended release 24 hr
- 1 tablet (30 mg) by oral route once daily
ER 34 mg tablet,extended release 24 hr
- 1 tablet (34 mg) by oral route once daily
ER 40 mg tablet,extended release 24 hr
- 1 tablet (40 mg) by oral route once daily
ER 8.5 mg tablet,extended release 24 hr
- 1 tablet (8.5 mg) by oral route once daily
Hypertension
- 1 tablet (17 mg) by oral route once daily
- 1 tablet (34 mg) by oral route once daily
- 1 tablet (8.5 mg) by oral route once daily
- Belladonna-phenobarbital
- carbamazepine
- Carbatrol
- Cerebyx
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Donnatal
- Epitol
- Equetro
- fosphenytoin
- itraconazole
- ketoconazole
- Luminal
- Mysoline
- Onmel
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- primidone
- Sporanox
- Sporanox Pulsepak
- Tegretol
- Tegretol Xr
Contraindicated
- amoxicil-clarithromy-lansopraz
- Biaxin
- Biaxin Xl
- Biaxin Xl Pak
- clarithromycin
- Dantrium
- dantrolene
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- Ketek
- Omeclamox-pak
- omeprazole-clarith-amoxicillin
- Prevpac
- Revonto
- telithromycin
Severe
Moderate
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- boceprevir
- cimetidine
- Diflucan
- fluconazole
- fluconazole in dextrose(iso-o)
- fluconazole in NaCl (iso-osm)
- Heartburn Relief
- Incivek
- isoniazid-rifamp-pyrazinamide
- Mycobutin
- Noxafil
- posaconazole
- Priftin
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- rifapentine
- Rifater
- Tagamet Hb
- telaprevir
- Vfend
- Vfend Iv
- Victrelis
- voriconazole
- Severe hypotension
Contraindicated
- Hypotension
- Severe coronary artery disease
Severe
Moderate
- Chronic heart failure
- Severe hepatic disease
SULAR (NISOLDIPINE)
- Hypertension
- Peripheral edema
- Headache disorder
More Frequent
Severe
Less Severe
- Chest pain
- Hypotension
- Progressive angina pectoris
- Skin rash
- Dizziness
- Nausea
- Palpitations
- Pharyngitis
- Sinusitis
- Vasodilation of blood vessels
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute myocardial infarction
- Anemia
- Angioedema
- Atrial fibrillation
- Cellulitis
- Cerebral ischemia
- Cerebrovascular accident
- Chest tightness
- Chronic heart failure
- Colitis
- Diabetes mellitus
- Dyspnea
- Exfoliative dermatitis
- First degree atrioventricular heart block
- Gastrointestinal hemorrhage
- Gingival hyperplasia
- Glaucoma
- Hepatomegaly
- Hypersensitivity drug reaction
- Hypokalemia
- Keratoconjunctivitis
- Leukopenia
- Maculopapular rash
- Myositis
- Orthostatic hypotension
- Peripheral venous insufficiency
- Pleural effusions
- Retinal detachment
- Supraventricular tachycardia
- Tachycardia
- Thyroiditis
- Ventricular premature beats
Less Severe
- Abnormal hepatic function tests
- Abnormal vaginal bleeding
- Acne vulgaris
- Acute bacterial otitis media
- Acute confusion
- Alopecia
- Amblyopia
- Anorexia
- Aphthous stomatitis
- Arthralgias
- Arthritis
- Asthma
- Ataxia
- Black tarry stools
- Blepharitis
- Chills
- Conjunctivitis
- Cough
- Cramps in legs
- Depression
- Diarrhea
- Dream disorder
- Drowsy
- Dry skin
- Dyschromia
- Dysgeusia
- Dyspepsia
- Dysphagia
- Dysuria
- Earache
- Ecchymosis
- Epistaxis
- Erectile dysfunction
- Eye tearing
- Facial edema
- Fever
- Flatulence
- Flu-like symptoms
- Gastritis
- Glossitis
- Gout
- Hematuria
- Hyperhidrosis
- Hypesthesia
- Hypotonia
- Increased appetite
- Increased urinary frequency
- Insomnia
- Laryngitis
- Libido changes
- Malaise
- Memory impairment
- Myalgias
- Nervousness
- Nocturia
- Ocular itching
- Paresthesia
- Petechiae
- Pruritus of skin
- Rhinitis
- Skin inflammation
- Skin ulcer
- Syncope
- Tenosynovitis
- Tinnitus
- Tremor
- Urticaria
- Vaginitis
- Vertigo
- Visual changes
- Vitreous floater
- Weight gain
- Weight loss
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Nisoldipine
Safety and efficacy not established in pediatrics.
- 1 Day – 18 Years
- Safety and efficacy not established in pediatrics.
Nisoldipine
- Severity Level:
C
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Nisoldipine
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Nisoldipine
Cardiovascular-Elderly are more sensitive to blood pressure lowering effects and may have lower drug clearance. Initial dose should not exceed 8.5 mg/day; titrate more slowly. Peripheral edema may be common. Gastrointestinal-may cause or worsen pre-existing constipation.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: Y
No Known Risk
None
- None
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
Formulary Reference Tool