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LIDOCAINE-HYDROCORTISONE (HYDROCORTISONE ACETATE/LIDOCAINE HCL)
- Hemorrhoids
- Anal fissure
- Proctitis
- Pruritus ani
- Lidocaine-hydrocortisone-aloe Vera Rectal Kit
- Lidocaine-hydrocortisone Topical Cream
- Lidocaine-hydrocortisone Rectal Kit
- Lidocaine-hydrocortisone Rectal Gel
- By Indication
-aloe vera 3 %-2.5 % (7 gram) rectal kit
- Apply to the affected area(s) by topical route 2 times per day
lidocaine 2 %-hydrocortisone 2 %-aloe vera rectal kit
- Insert the contents of 1 tube by rectal route 2 times per day via applicator
lidocaine 3 %-hydrocortisone 0.5 % topical cream
- Apply a thin layer to the affected area(s) by topical route 3 times per day
lidocaine 2 %-hydrocortisone 2 % (7 gram) rectal kit cream and wipes
- Apply to the affected area(s) by topical route 2 times per day
lidocaine 3 %-hydrocortisone 0.5 % rectal kit
- Insert 1 applicatorful by rectal route 2 times per day
lidocaine 3 %-hydrocortisone 1 % (7 gram) rectal kit
- Insert 1 applicatorful by rectal route 2 times per day
lidocaine 3 %-hydrocortisone 2.5 % (7 gram) rectal gel
- Insert 1 applicatorful by rectal route 2 times per day
Anal fissure
- Insert 1 applicatorful by rectal route 2 times per day
- Insert the contents of 1 tube by rectal route 2 times per day via applicator
- Apply to the affected area(s) by topical route 2 times per day
Hemorrhoids
- Insert 1 applicatorful by rectal route 2 times per day
- Insert the contents of 1 tube by rectal route 2 times per day via applicator
- Apply to the affected area(s) by topical route 2 times per day
Proctitis
- Insert 1 applicatorful by rectal route 2 times per day
- Insert the contents of 1 tube by rectal route 2 times per day via applicator
- Apply to the affected area(s) by topical route 2 times per day
Pruritus ani
- Insert 1 applicatorful by rectal route 2 times per day
- Insert the contents of 1 tube by rectal route 2 times per day via applicator
- Apply to the affected area(s) by topical route 2 times per day
Pruritus of skin
- Apply a thin layer to the affected area(s) by topical route 2 times per day
- Apply a thin layer to the affected area(s) by topical route 3 times per day
Skin inflammation
- Apply a thin layer to the affected area(s) by topical route 2 times per day
- Apply a thin layer to the affected area(s) by topical route 3 times per day
- None
Contraindicated
- None
Severe
Moderate
- None
- Intestinal abscess
- Large open wound
- Methemoglobinemia
- Untreated systemic fungal infection
Contraindicated
- Active tuberculosis
- Diabetes mellitus
- Glucose-6-phosphate dehydrogenase (g6Pd) deficiency
- Heart block
- Hemolytic anemia from PK and g6PD deficiencies
- Infection
- Intestinal anastomosis
- Ocular herpes simplex
- Ocular hypertension
- Sepsis
- Shock
Severe
Moderate
- Chronic heart failure
- Disease of liver
- Diverticulitis of gastrointestinal tract
- Gastrointestinal fistula
- Herpes simplex infection
- Hypertension
- Hyperthyroidism
- Hypothalamic-pituitary insufficiency
- Hypothyroidism
- Kidney disease with reduction in GFR
- Measles
- Open angle glaucoma
- Osteoporosis
- Psychotic disorder
- Respiratory depression
- Seizure disorder
- Varicella zoster virus infection
LIDOCAINE-HYDROCORTISONE (HYDROCORTISONE ACETATE/LIDOCAINE HCL)
- Hemorrhoids
- Anal fissure
- Proctitis
- Pruritus ani
- Infection
- Erythema
- Increased appetite
- Stinging of skin
More Frequent
Severe
Less Severe
- Adrenal cortical insufficiency
- Angioedema
- Dermatitis due to topical drug
- Erythema
- Folliculitis
- Hypercortisolism
- Pruritus of skin
- Purpura
- Skin and skin structure infection
- Skin atrophy
- Skin rash
- Stinging of skin
- Urticaria
- Headache disorder
- Irregular menstrual periods
- Nausea
- Paresthesia
- Pruritus of skin
- Skin rash
- Telangiectasia
- Treatment site sequelae
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abdominal distension
- Abnormal hepatic function tests
- Acute confusion
- Acute respiratory insufficiency
- Adrenal cortical insufficiency
- Anaphylaxis
- Body fluid retention
- Bradycardia
- Bullous dermatitis
- Cardiac arrhythmia
- Cataracts
- Central serous chorioretinopathy
- Chronic heart failure
- CNS toxicity
- Cyanosis
- Delirium
- Drowsy
- Drug-induced psychosis
- Dyspnea
- Excitement
- Eyelid edema
- Gastrointestinal hemorrhage
- Glaucoma
- Glycosuria
- Hallucinations
- Headache disorder
- Hepatomegaly
- Hyperglycemia
- Hypertension
- Hypotension
- Hypothalamic-pituitary insufficiency
- Idiopathic intracranial hypertension
- Impaired wound healing
- Intestinal perforation
- Methemoglobinemia
- Myopathy
- Ocular hypertension
- Osteoporosis
- Paranoid disorder
- Peptic ulcer
- Personality disorders
- Pulmonary edema
- Respiratory depression
- Seizure disorder
- Skin hypopigmentation
- Skin striae
- Skin ulcer
- Thromboembolic disorder
- Tremor
- Unconsciousness
- Urticaria
Less Severe
- Acne vulgaris
- Acneiform eruption
- Acute confusion
- Allergic dermatitis
- Alopecia
- Apprehension
- Blistering skin
- Blurred vision
- Contact dermatitis
- Depression
- Dizziness
- Dry skin
- Dyschromia
- Edema
- Euphoria
- Flushing
- Glycosuria
- Hirsutism
- Hypercortisolism
- Hyperesthesia
- Hyperglycemia
- Insomnia
- Lipodystrophy
- Miliaria
- Mood changes
- Nervousness
- Perioral dermatitis
- Rectal irritation
- Sensation of cold
- Sensation of warmth
- Skin irritation
- Sleep disorder
- Tinnitus
- Twitching
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Hydrocortisone (topical, Non-systemic)
- Severity Level:
2
- Additional Notes: Systemic absorption unknown; insuff human data
Lidocaine
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
Hydrocortisone (top., Rectal)
Insufficient data available; limited use may pose little risk
Amount excreted reported to be low with low infant oral bioavailability
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Unknown | Not known; no or inclusive data | Insufficient data available; limited use may pose little risk |
Lidocaine
Insufficient data available; limited use may pose little risk
Amount excreted reported to be low with low infant oral bioavailability
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | Not known; no or inclusive data | Amount excreted reported to be low with low infant oral bioavailability |
Contraindicated
None
Precaution Exists
Select Anesthetics
General-May be more sensitive to CNS and cardiac adverse reactions. Consider dose reduction due to reduced clearance in the elderly.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Anal fissure | |
| K60.0 | Acute anal fissure |
| K60.1 | Chronic anal fissure |
| K60.2 | Anal fissure, unspecified |
| Hemorrhoids | |
| K64.0 | First degree hemorrhoids |
| K64.8 | Other hemorrhoids |
| K64.9 | Unspecified hemorrhoids |
| O22.4 | Hemorrhoids in pregnancy |
| O22.40 | Hemorrhoids in pregnancy, unspecified trimester |
| O22.41 | Hemorrhoids in pregnancy, first trimester |
| O22.42 | Hemorrhoids in pregnancy, second trimester |
| O22.43 | Hemorrhoids in pregnancy, third trimester |
| O87.2 | Hemorrhoids in the puerperium |
| Proctitis | |
| K62.7 | Radiation proctitis |
| K62.89 | Other specified diseases of anus and rectum |
| Pruritus ani | |
| L29.0 | Pruritus ani |
| L29.3 | Anogenital pruritus, unspecified |
| 0-9 | A-Z |
|---|---|
| K60.0 | Acute anal fissure |
| K60.1 | Chronic anal fissure |
| K60.2 | Anal fissure, unspecified |
| K62.7 | Radiation proctitis |
| K62.89 | Other specified diseases of anus and rectum |
| K64.0 | First degree hemorrhoids |
| K64.8 | Other hemorrhoids |
| K64.9 | Unspecified hemorrhoids |
| L29.0 | Pruritus ani |
| L29.3 | Anogenital pruritus, unspecified |
| O22.4 | Hemorrhoids in pregnancy |
| O22.40 | Hemorrhoids in pregnancy, unspecified trimester |
| O22.41 | Hemorrhoids in pregnancy, first trimester |
| O22.42 | Hemorrhoids in pregnancy, second trimester |
| O22.43 | Hemorrhoids in pregnancy, third trimester |
| O87.2 | Hemorrhoids in the puerperium |
Formulary Reference Tool