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CLARINEX-D 12 HOUR (DESLORATADINE/PSEUDOEPHEDRINE SULFATE)
- Seasonal allergic rhinitis
2.5 mg-120 mg tablet,extended release
- 1 tablet by oral route 2 times per day
2.5 mg-120 mg tablet,extended release
- 1 tablet by oral route 2 times per day
Seasonal allergic rhinitis
- 1 tablet by oral route 2 times per day
- isocarboxazid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- tranylcypromine
Contraindicated
- Azilect
- bromocriptine
- cabergoline
- Cafergot
- Cycloset
- D.h.e.45
- dihydroergotamine
- Eldepryl
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- linezolid
- methylergonovine
- Migergot
- Migranal
- Parlodel
- rasagiline
- selegiline HCl
- Zelapar
- Zyvox
Severe
Moderate
- methyldopa
- methyldopa-hydrochlorothiazide
- methyldopate
- reserpine
- Angle-closure glaucoma
- Severe coronary artery disease
- Severe uncontrolled hypertension
- Urinary retention
Contraindicated
- Benign prostatic hyperplasia
- Diabetes mellitus
- Disease of liver
- Hypertension
- Hyperthyroidism
- Kidney disease with reduction in GFR
Severe
Moderate
- None
CLARINEX-D 12 HOUR (DESLORATADINE/PSEUDOEPHEDRINE SULFATE)
- Seasonal allergic rhinitis
- None
- Drowsy
- Dysmenorrhea
- Fatigue
- Headache disorder
- Insomnia
- Myalgias
- Pharyngitis
- Pruritus of skin
- Skin rash
- Xerostomia
More Frequent
Severe
Less Severe
- None
- Agitation
- Anorexia
- Dizziness
- Drowsy
- Dyspepsia
- Dysuria
- General weakness
- Nausea
- Nervousness
- Pallor
- Tachycardia
- Tremor
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Acquired dystonia
- Acute generalized exanthematous pustulosis
- Anaphylaxis
- Dyspnea
- Extrapyramidal disease
- Hallucinations
- Hepatitis
- Hyperbilirubinemia
- Hypersensitivity drug reaction
- Hypertension
- Increased appetite
- Ischemic colitis
- Motor tic disorder
- Seizure disorder
- Tachycardia
- Urticaria
- Vomiting
Less Severe
- Abdominal pain with cramps
- Cardiac arrhythmia
- Dyspepsia
- Edema
- Excitement
- Hyperhidrosis
- Palpitations
- Symptoms of anxiety
Contraindicated
Pseudoephedrine (SR or High Dose)
Increased sensitivity to side effects. Dose form or strength not appropriate.
- 1 Day – 12 Years
- 1 Increased sensitivity to side effects. Dose form or strength not appropriate.
Severe Precaution
None
Management or Monitoring Precaution
Desloratadine (select)
Dose form not appropriate age < 6 years.
- 1 Day – 6 Years
- Dose form not appropriate age < 6 years.
Desloratadine
- Severity Level:
C
- Additional Notes:
Pseudoephedrine
- Severity Level:
C
- Additional Notes: Fda c w/combo prod; poss risk of gastroschisis/sia with 1st trimester exposure
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Desloratadine
Limited data suggest low amounts excreted
May decrease milk supply, and cause irritability
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest low amounts excreted |
Pseudoephedrine
Limited data suggest low amounts excreted
May decrease milk supply, and cause irritability
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Drug shown to have adverse effect | May decrease milk supply, and cause irritability |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Pseudoephedrine
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Seasonal allergic rhinitis | |
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| 0-9 | A-Z |
|---|---|
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
Formulary Reference Tool