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Drug overview for MOXIFLOXACIN (moxifloxacin hcl):
Generic name: MOXIFLOXACIN HCL (mox-ih-FLOX-uh-sin)
Drug class: Ophthalmic Antibacterials
Therapeutic class: Ophthalmic Agents
Moxifloxacin is a fluoroquinolone anti-infective agent.
No enhanced Uses information available for this drug.
Generic name: MOXIFLOXACIN HCL (mox-ih-FLOX-uh-sin)
Drug class: Ophthalmic Antibacterials
Therapeutic class: Ophthalmic Agents
Moxifloxacin is a fluoroquinolone anti-infective agent.
No enhanced Uses information available for this drug.
DRUG IMAGES
MOXIFLOXACIN 0.5% EYE DROPS
The following indications for MOXIFLOXACIN (moxifloxacin hcl) have been approved by the FDA:
Indications:
Bacterial conjunctivitis
Professional Synonyms:
Inflammation of the conjunctiva due to bacteria
Indications:
Bacterial conjunctivitis
Professional Synonyms:
Inflammation of the conjunctiva due to bacteria
The following dosing information is available for MOXIFLOXACIN (moxifloxacin hcl):
Moxifloxacin is commercially available for topical ophthalmic administration as moxifloxacin hydrochloride; dosage is expressed in terms of moxifloxacin.
No enhanced Administration information available for this drug.
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| MOXIFLOXACIN 0.5% EYE DROPS | Maintenance | Adults instill 1 drop into affected eye(s) by ophthalmic route 3 times per day |
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| MOXIFLOXACIN 0.5% EYE DROPS | Maintenance | Adults instill 1 drop into affected eye(s) by ophthalmic route 3 times per day |
The following drug interaction information is available for MOXIFLOXACIN (moxifloxacin hcl):
There are 0 contraindications.
There are 0 severe interactions.
There are 0 moderate interactions.
The following contraindication information is available for MOXIFLOXACIN (moxifloxacin hcl):
Drug contraindication overview.
Moxifloxacin 0.5% ophthalmic solution is contraindicated in patients with known hypersensitivity to moxifloxacin, other quinolones, or any component in the formulation.
Moxifloxacin 0.5% ophthalmic solution is contraindicated in patients with known hypersensitivity to moxifloxacin, other quinolones, or any component in the formulation.
There are 0 contraindications.
There are 0 severe contraindications.
There are 1 moderate contraindications.
Clinically significant contraindication, where the condition can be managed or treated before the drug may be given safely.
| Moderate List |
|---|
| No disease contraindications |
The following adverse reaction information is available for MOXIFLOXACIN (moxifloxacin hcl):
Adverse reaction overview.
Moxifloxacin 0.5% ophthalmic solution (Moxeza(R)): Adverse effects reported in 1-2% of patients include eye irritation, pyrexia, and conjunctivitis. Moxifloxacin 0.5%
ophthalmic solution (Vigamox(R)): Adverse effects reported in approximately 1-6% of patients include conjunctivitis, decreased visual acuity, ocular dryness, keratitis, ocular discomfort/pain/pruritus, ocular hyperemia, subconjunctival hemorrhage, and tearing. Adverse systemic effects reported in approximately 1-4% of patients include fever, increased cough, infection, otitis media, pharyngitis, rash, and rhinitis.
Moxifloxacin 0.5% ophthalmic solution (Moxeza(R)): Adverse effects reported in 1-2% of patients include eye irritation, pyrexia, and conjunctivitis. Moxifloxacin 0.5%
ophthalmic solution (Vigamox(R)): Adverse effects reported in approximately 1-6% of patients include conjunctivitis, decreased visual acuity, ocular dryness, keratitis, ocular discomfort/pain/pruritus, ocular hyperemia, subconjunctival hemorrhage, and tearing. Adverse systemic effects reported in approximately 1-4% of patients include fever, increased cough, infection, otitis media, pharyngitis, rash, and rhinitis.
There are 11 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
|
Conjunctivitis Keratitis Ocular itching Ocular pain Reduced visual acuity Subconjunctival hemorrhage |
Conjunctival hyperemia |
| Rare/Very Rare |
|---|
|
Acute bacterial otitis media Fever Hypersensitivity drug reaction Infection |
There are 7 less severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
|
Dry eye Eye tearing |
Ocular discomfort |
| Rare/Very Rare |
|---|
|
Cough Pharyngitis Rhinitis Skin rash |
The following precautions are available for MOXIFLOXACIN (moxifloxacin hcl):
Moxifloxacin 0.5% ophthalmic solution (Moxeza(R)): Safety and efficacy have not been established in infants younger than 4 months of age. Moxifloxacin 0.5%
ophthalmic solution (Vigamox(R)): Safety and efficacy have not been not established in infants younger than 1 year of age. Although systemic quinolones have been associated with arthropathy in immature animals, there is no evidence that administration of moxifloxacin ophthalmic solution has any effect on weight bearing joints.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
ophthalmic solution (Vigamox(R)): Safety and efficacy have not been not established in infants younger than 1 year of age. Although systemic quinolones have been associated with arthropathy in immature animals, there is no evidence that administration of moxifloxacin ophthalmic solution has any effect on weight bearing joints.
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
Category C. (See Users Guide.) Data are not available regarding use of moxifloxacin 0.5% ophthalmic solution in pregnant women, and the drug should be used during pregnancy only if potential benefits to the woman justify potential risks to the fetus. In animal studies using oral moxifloxacin, reduced fetal weight and delayed fetal skeletal development were reported.
Although distribution of moxifloxacin into milk following ophthalmic administration has not been studied, it is presumed that the drug is distributed into human milk. Caution is advised if moxifloxacin ophthalmic solution is used in nursing women.
No overall differences in safety and efficacy of moxifloxacin 0.5% ophthalmic solution have been observed between geriatric and younger adults.
The following prioritized warning is available for MOXIFLOXACIN (moxifloxacin hcl):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for MOXIFLOXACIN (moxifloxacin hcl)'s list of indications:
| Bacterial conjunctivitis | |
| H10.02 | Other mucopurulent conjunctivitis |
| H10.021 | Other mucopurulent conjunctivitis, right eye |
| H10.022 | Other mucopurulent conjunctivitis, left eye |
| H10.023 | Other mucopurulent conjunctivitis, bilateral |
| H10.029 | Other mucopurulent conjunctivitis, unspecified eye |
| H10.3 | Unspecified acute conjunctivitis |
| H10.30 | Unspecified acute conjunctivitis, unspecified eye |
| H10.31 | Unspecified acute conjunctivitis, right eye |
| H10.32 | Unspecified acute conjunctivitis, left eye |
| H10.33 | Unspecified acute conjunctivitis, bilateral |
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