RELISTOR (METHYLNALTREXONE BROMIDE)

150 mg tablet

• 3 tablets (450 mg) by oral route once daily in the morning

12 mg/0.6 mL subcutaneous syringe

• Inject 0.6 milliliter (12 mg) by subcutaneous route every other day as needed (for patients weighing 62Kg to 114Kg)

8 mg/0.4 mL subcutaneous syringe

• Inject 0.4 milliliter (8 mg) by subcutaneous route every other day asneeded (for patients weighing 38Kg to <62Kg)

12 mg/0.6 mL subcutaneous solution

• Inject 0.15 mg/kg by subcutaneous route every other day (for patientsweighing <38Kg and >114Kg)

Opioid-induced constipation

• Inject 0.4 milliliter (8 mg) by subcutaneous route every other day asneeded (for patients weighing 38Kg to <62Kg)

• Inject 0.4 milliliter (8 mg) by subcutaneous route every other day (for patients weighing 38Kg to <62Kg)

• Inject 0.4 milliliter (8 mg) by subcutaneous route once daily as needed (for patients weighing 38Kg to <62Kg)

• Inject 0.4 milliliter (8 mg) by subcutaneous route once daily (for patients weighing 38Kg to <62Kg)

• Inject 0.6 milliliter (12 mg) by subcutaneous route every other day as needed (for patients weighing 62Kg to 114Kg)

• Inject 0.6 milliliter (12 mg) by subcutaneous route every other day (for patients weighing 62Kg to 114Kg)

• Inject 0.6 milliliter (12 mg) by subcutaneous route once daily as needed (for patients weighing 62Kg to 114Kg)

• Inject 0.6 milliliter (12 mg) by subcutaneous route once daily (for patients weighing 62Kg to 114Kg)

• 3 tablets (450 mg) by oral route once daily in the morning

• Inject 0.15 mg/kg by subcutaneous route every other day as needed (for patients weighing <38Kg and >114Kg)

• Inject 0.15 mg/kg by subcutaneous route every other day (for patientsweighing <38Kg and >114Kg)

• Inject 0.15 mg/kg by subcutaneous route once daily as needed (for patients weighing <38Kg and >114Kg)

• Inject 0.15 mg/kg by subcutaneous route once daily (for patients weighing <38Kg and >114Kg)