INVIRASE (SAQUINAVIR MESYLATE)

Contraindicated



• Advicor
• alfuzosin
• Altoprev
• amiodarone
• amiodarone in dextrose,iso-osm
• apixaban
• avanafil
• B cplx-C-St.Johnwrt-K.&S.ginsg
• Brilinta
• bromocriptine
• cabergoline
• Cafergot
• calcium-mag-B complex-D3-hrb61
• Camptosar
• Cold & Flu Fighter
• conivaptan in 5 % dextrose
• Cordarone
• Cycloset
• D.h.e.45
• Detrol La
• dextromethorphan-quinidine
• dihydroergotamine
• dofetilide
• dronedarone
• dutasteride-tamsulosin
• eletriptan HBr
• Eliquis
• elvitegr-cobicist-emtric-tenof
• ergoloid
• Ergomar
• ergotamine tartrate
• ergotamine-caffeine
• Ez Use Joint-tunnel-trigger
• ezetimibe-simvastatin
• Fatigue Relief Complex
• flecainide
• Flomax
• irinotecan
• isoniazid-rifamp-pyrazinamide
• Jalyn
• Juxtapid
• Kombiglyze Xr
• Latuda
• lidocaine (PF)
• lidocaine in D5W (PF)
• lomitapide
• lovastatin
• lurasidone
• methylergonovine
• Mevacor
• midazolam
• midazolam (PF)
• Migergot
• Migranal
• Multaq
• Nexterone
• niacin-lovastatin
• niacin-simvastatin
• Nuedexta
• Oleptro Er
• Orap
• Pacerone
• Parlodel
• pimozide
• propafenone
• quinidine gluconate
• quinidine sulfate
• Rapaflo
• Relpax
• Revatio
• Rifadin
• Rifamate
• rifampin
• rifampin-isoniazid
• Rifater
• rivaroxaban
• Rythmol
• Samsca
• saxagliptin-metformin
• sildenafil
• silodosin
• Simcor
• simvastatin
• St. John's wort
• Stendra
• Stribild
• tamsulosin
• ticagrelor
• Tikosyn
• tolterodine
• tolvaptan
• trazodone
• triamcinolone-lidocaine
• triazolam
• Uroxatral
• Vaprisol
• vit C-St. John wort-elder-hb30
• Vytorin 10-10
• Vytorin 10-20
• Vytorin 10-40
• Vytorin 10-80
• Women's Complex
• Xarelto
• Xylocaine (cardiac) (pf)
• Zocor

Severe



• A-methapred
• Abstral
• Actiq
• Advair Diskus
• Advair Hfa
• Afinitor
• Afinitor Disperz
• Alfenta
• alfentanil
• Altavera (28)
• Alyacen 1/35 (28)
• Alyacen 7/7/7 (28)
• Amethia
• Amethia Lo
• Amethyst
• Apokyn
• apomorphine
• Apri
• Aptivus
• Aranelle (28)
• Aristospan Intra-articular
• Aristospan Intralesional
• arsenic trioxide
• Aubra
• Aviane
• azelastine-fluticasone
• Azurette (28)
• B6-FA-B12-co Q10-herb no.225
• Balziva (28)
• Beauty & Skin Therapy
• bedaquiline
• Betapace
• Betapace Af
• Beyaz
• bosentan
• Breo Ellipta
• Brevicon (28)
• Briellyn
• budesonide
• budesonide-formoterol
• Camila
• Camrese
• Camrese Lo
• Caprelsa
• carbamazepine
• Carbatrol
• Caziant (28)
• Celexa
• Chateal
• chloroquine phosphate
• chlorpromazine
• citalopram
• colchicine
• colchicine-probenecid
• Colcrys
• Corvert
• Cryselle (28)
• Cyclafem 1/35 (28)
• Cyclafem 7/7/7 (28)
• Cyclessa (28)
• darunavir
• Dasetta 1/35 (28)
• Dasetta 7/7/7 (28)
• Daysee
• Depo-medrol
• Depo-provera
• Depo-subq Provera 104
• desog-e.estradiol/e.estradiol
• Desogen
• desogestrel-ethinyl estradiol
• dexamethasone
• Dexamethasone Intensol
• dexamethasone sodium phos (PF)
• dexamethasone sodium phosphate
• Dexpak 10 Day
• Dexpak 13 Day
• Dexpak 6 Day
• Diskets
• disopyramide
• Dolophine
• droperidol
• drospirenone-e.estradiol-lm.FA
• drospirenone-ethinyl estradiol
• Duragesic
• Dymista
• Elinest
• Emoquette
• Endocet
• Endodan
• Enpresse
• Enskyce
• Entocort Ec
• Epitol
• Equetro
• Errin
• Erythrocin
• erythromycin
• erythromycin-sulfisoxazole
• escitalopram oxalate
• Estarylla
• estradiol valerate-dienogest
• Estrostep Fe-28
• ethynodiol diac-eth estradiol
• etonogestrel
• etonogestrel-ethinyl estradiol
• everolimus
• Falmina (28)
• Fareston
• Femcon Fe
• fentanyl
• fentanyl citrate
• fentanyl citrate (PF)
• Fentora
• Flo-pred
• Flonase
• Flovent Diskus
• Flovent Hfa
• fluticasone
• fluticasone furoate
• fluticasone-salmeterol
• fluticasone-vilanterol
• Fortavit
• Generess Fe
• Gianvi (28)
• Gildagia
• Gildess
• Gildess Fe
• guanfacine
• Haldol
• Haldol Decanoate
• haloperidol
• haloperidol decanoate
• haloperidol lactate
• Healthy Heart Complex
• Heather
• ibuprofen-oxycodone
• ibutilide fumarate
• Introvale
• Intuniv Er
• Invega
• Invega Sustenna
• isradipine
• Jencycla
• Jolessa
• Jolivette
• Junel 1.5/30 (21)
• Junel 1/20 (21)
• Junel Fe 1.5/30 (28)
• Junel Fe 1/20 (28)
• Kariva (28)
• Kelnor 1/35 (28)
• Kenalog
• Kurvelo
• L norgest&E estradiol-E estrad
• Larin 1/20 (21)
• Larin Fe
• Lazanda
• Leena 28
• Lessina
• Levonest (28)
• levonorg-eth estrad triphasic
• levonorgestrel
• levonorgestrel-ethinyl estrad
• Levora 0.15/30 (28)
• Levora-28
• Lexapro
• Lo Loestrin Fe
• Loestrin 1.5/30 (21)
• Loestrin 1/20 (21)
• Loestrin Fe 1.5/30 (28)
• Loestrin Fe 1/20 (28)
• Lomedia 24 Fe
• Loryna (28)
• Loseasonique
• Low-ogestrel (28)
• Lutera (28)
• Lyza
• macitentan
• Marlissa
• Maximum Daily Green
• Medrol
• Medrol (pak)
• medroxyprogesterone
• Megavite
• Megavite Golden Years 55+
• methadone
• Methadone Intensol
• Methadose
• methylprednisolone
• methylprednisolone acetate
• methylprednisolone sod suc(PF)
• methylprednisolone sodium succ
• methylprednisolone-bupivacaine
• Microgestin 1.5/30 (21)
• Microgestin 1/20 (21)
• Microgestin Fe 1.5/30 (28)
• Microgestin Fe 1/20 (28)
• Millipred
• Millipred Dp
• Minastrin 24 Fe
• Mircette (28)
• Mirena
• Modicon (28)
• Mono-linyah
• Mononessa (28)
• MSM-collag-co Q10-herb no.226
• multivit-Fe-min-DNA-RNA-dsup4
• mv-iron-FA-Ca-beepoln-hb 101
• mv-mn-FA-herbs190&215-digest#4
• mv-mn-FA-lycopene-lut-#178herb
• mv-mn-iron-FA-herbal cmplx#190
• My Way
• Mycobutin
• Myzilra
• Nasacort
• Nasacort Aq
• Natazia
• Nebupent
• Necon 0.5/35 (28)
• Necon 1/35 (28)
• Necon 1/50 (28)
• Necon 10/11 (28)
• Necon 7/7/7 (28)
• nevirapine
• Nexplanon
• Next Choice One Dose
• Nor-qd
• Nora-be
• norelgestrom-ethinyl estradiol
• noreth-ethinyl estradiol-iron
• norethin-e.estradiol triphasic
• norethin-eth estrad biphasic
• norethindrone (contraceptive)
• norethindrone ac-eth estradiol
• norethindrone-e.estradiol-iron
• norethindrone-ethin estradiol
• norethindrone-mestranol
• norfloxacin
• norgestimate-ethinyl estradiol
• norgestrel-ethinyl estradiol
• Norinyl 1+35 (28)
• Norinyl 1+50 (28)
• Noroxin
• Norpace
• Norpace Cr
• Nortrel 0.5/35 (28)
• Nortrel 1/35 (21)
• Nortrel 1/35 (28)
• Nortrel 7/7/7 (28)
• Nuvaring
• Ocella
• Ogestrel (28)
• Olysio
• Opsumit
• Orapred
• Orapred Odt
• Orsythia
• Ortho Evra
• Ortho Micronor
• Ortho Tri-cyclen (28)
• Ortho Tri-cyclen Lo (28)
• Ortho-cept (28)
• Ortho-cyclen (28)
• Ortho-novum 1/35 (28)
• Ortho-novum 7/7/7 (28)
• Ovcon-35 (28)
• Oxecta
• oxycodone
• oxycodone-acetaminophen
• oxycodone-aspirin
• Oxycontin
• paliperidone
• paliperidone palmitate
• pasireotide
• Pediapred
• Pentam
• pentamidine
• Percocet
• Percodan
• Philith
• Physicians Ez Use M-pred
• Pimtrea (28)
• Pirmella
• Plan B One-step
• policosan-inositol niac-garlic
• Policosanol-garlic-niacin
• Portia
• prednisolone
• prednisolone acetate
• prednisolone sodium phosphate
• prednisone
• Prednisone Intensol
• Previfem
• Prezista
• Priftin
• Primlev
• procainamide
• Pulmicort
• Pulmicort Flexhaler
• Qualaquin
• Quartette
• Quasense
• quinine sulfate
• Rayos
• Reclipsen (28)
• Rhinocort Aqua
• rifabutin
• rifapentine
• Roxicet
• Safyral
• salmeterol
• Seasonique
• Serevent Diskus
• Signifor
• simeprevir
• Sirturo
• Skyla
• Solu-medrol
• Solu-medrol (pf)
• Sorine
• sotalol
• Sotalol Af
• Sprintec (28)
• Sronyx
• Sublimaze (pf)
• Subsys
• Syeda
• Symbicort
• Tegretol
• Tegretol Xr
• Tenex
• thioridazine
• Tilia Fe
• tipranavir
• toremifene
• Tracleer
• Tri-estarylla
• Tri-legest Fe
• Tri-linyah
• Tri-norinyl (28)
• Tri-previfem (28)
• Tri-sprintec (28)
• triamcinolone acetonide
• triamcinolone hexacetonide
• Trinessa (28)
• Trisenox
• Trivora (28)
• Uceris
• vandetanib
• Velivet Triphasic Regimen (28)
• Veramyst
• Veripred 20
• Vestura (28)
• Viorele (28)
• Viramune
• Viramune Xr
• Vyfemla (28)
• Wera (28)
• Wymzya Fe
• Xartemis Xr
• Yasmin (28)
• Yaz 28
• Zarah
• Zenchent (28)
• Zenchent Fe
• Zeosa
• Zortress
• Zovia 1/35E (28)
• Zovia 1/50E (28)

Contraindicated



• Congenital long QT syndrome
• Lactating mother
• Torsades de pointes

Severe



• Alcoholism
• Complete atrioventricular block
• Disease of liver
• Hepatic cirrhosis
• Hypokalemia
• Hypomagnesemia
• Prolonged QT interval
• Second degree atrioventricular heart block

Contraindicated

None

Severe Precaution

None

Management or Monitoring Precaution

Saquinavir

Adjusting dose in order to avoid QT interval prolongation may provide inadequate antiviral activity. No efficacy data available for dose < 50 mg/kg. Increased risk of gastrointestinal adverse events. Safety and efficacy not established age < 16 years.

• 1 Day – 16 Years
• Adjusting dose in order to avoid QT interval prolongation may provide inadequate antiviral activity. No efficacy data available for dose < 50 mg/kg. Increased risk of gastrointestinal adverse events. Safety and efficacy not established age < 16 years.