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VAGICAINE (BENZOCAINE/RESORCINOL)
- Minor skin wound pain
- Pruritus of skin
- Skin irritation
- Vagisil Topical Cream
- Vaginal Itch Topical Cream
- Vagicaine Topical Cream
- Anti-itch (benzocaine-resorcinol) Topical Cream
20 %-3 % topical cream
- Dosage information is not available
5 %-2 % topical cream
- Dosage information is not available
Vaginal Itch 5 %-2 % topical cream
- Dosage information is not available
20 %-3 % topical cream
- Dosage information is not available
5 %-2 % topical cream
- Dosage information is not available
Anti-Itch (benzocaine-resorcinol) 5 %-2 % topical cream
- Dosage information is not available
- None
Contraindicated
- None
Severe
Moderate
- None
- Large open wound
- Methemoglobinemia
Contraindicated
- Cardiac arrhythmia
- Glucose-6-phosphate dehydrogenase (g6Pd) deficiency
- Hemolytic anemia from PK and g6PD deficiencies
Severe
Moderate
- Respiratory depression
- Seizure disorder
VAGICAINE (BENZOCAINE/RESORCINOL)
- Minor skin wound pain
- Pruritus of skin
- Skin irritation
- None
- Abnormal desquamation
- Skin inflammation
More Frequent
Severe
Less Severe
- Angioedema
- Dermatitis due to topical drug
- Erythema
- Pruritus of skin
- Skin irritation
- Skin rash
- Stinging of skin
- Urticaria
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute respiratory insufficiency
- Anaphylaxis
- Bradycardia
- Cardiac arrhythmia
- CNS toxicity
- Cyanosis
- Drowsy
- Eyelid edema
- Headache disorder
- Hyperhidrosis
- Hypotension
- Methemoglobinemia
- Respiratory depression
- Seizure disorder
- Tremor
- Unconsciousness
Less Severe
- Acute confusion
- Apprehension
- Blurred vision
- Dizziness
- Edema
- Euphoria
- Nervousness
- Sensation of cold
- Sensation of warmth
- Tinnitus
- Twitching
- Vomiting
Contraindicated
None
Severe Precaution
Benzocaine (Top,Rectal,Misc)
Increased risk for developing methemoglobinemia. Consult clinician for use age < 2 years.
- 1 Day – 2 Years
- Increased risk for developing methemoglobinemia. Consult clinician for use age < 2 years.
Management or Monitoring Precaution
None
Benzocaine(topical)
- Severity Level:
2
- Additional Notes: Briggs suggests no known evidence of dev tox with topical agents
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Benzocaine
Reports of infant methemoglobinemia after ingestion of topical benzocaine
Insufficient data available; drug is absorbed through intact & broken skin.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | No adverse effect | Reports of infant methemoglobinemia after ingestion of topical benzocaine |
Resorcinol
Reports of infant methemoglobinemia after ingestion of topical benzocaine
Insufficient data available; drug is absorbed through intact & broken skin.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available; drug is absorbed through intact & broken skin. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Select Anesthetics
General-May be more sensitive to CNS and cardiac adverse reactions. Consider dose reduction due to reduced clearance in the elderly.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | Y | N | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Pruritus of skin | |
| L29.8 | Other pruritus |
| L29.9 | Pruritus, unspecified |
| Skin irritation | |
| L24 | Irritant contact dermatitis |
| L24.0 | Irritant contact dermatitis due to detergents |
| L24.1 | Irritant contact dermatitis due to oils and greases |
| L24.2 | Irritant contact dermatitis due to solvents |
| L24.3 | Irritant contact dermatitis due to cosmetics |
| L24.4 | Irritant contact dermatitis due to drugs in contact with skin |
| L24.5 | Irritant contact dermatitis due to other chemical products |
| L24.6 | Irritant contact dermatitis due to food in contact with skin |
| L24.7 | Irritant contact dermatitis due to plants, except food |
| L24.8 | Irritant contact dermatitis due to other agents |
| L24.81 | Irritant contact dermatitis due to metals |
| L24.89 | Irritant contact dermatitis due to other agents |
| L24.9 | Irritant contact dermatitis, unspecified cause |
| L25 | Unspecified contact dermatitis |
| L25.0 | Unspecified contact dermatitis due to cosmetics |
| L25.1 | Unspecified contact dermatitis due to drugs in contact with skin |
| L25.2 | Unspecified contact dermatitis due to dyes |
| L25.3 | Unspecified contact dermatitis due to other chemical products |
| L25.4 | Unspecified contact dermatitis due to food in contact with skin |
| L25.5 | Unspecified contact dermatitis due to plants, except food |
| L25.8 | Unspecified contact dermatitis due to other agents |
| L25.9 | Unspecified contact dermatitis, unspecified cause |
| L30.9 | Dermatitis, unspecified |
| R21 | Rash and other nonspecific skin eruption |
| 0-9 | A-Z |
|---|---|
| L24 | Irritant contact dermatitis |
| L24.0 | Irritant contact dermatitis due to detergents |
| L24.1 | Irritant contact dermatitis due to oils and greases |
| L24.2 | Irritant contact dermatitis due to solvents |
| L24.3 | Irritant contact dermatitis due to cosmetics |
| L24.4 | Irritant contact dermatitis due to drugs in contact with skin |
| L24.5 | Irritant contact dermatitis due to other chemical products |
| L24.6 | Irritant contact dermatitis due to food in contact with skin |
| L24.7 | Irritant contact dermatitis due to plants, except food |
| L24.8 | Irritant contact dermatitis due to other agents |
| L24.81 | Irritant contact dermatitis due to metals |
| L24.89 | Irritant contact dermatitis due to other agents |
| L24.9 | Irritant contact dermatitis, unspecified cause |
| L25 | Unspecified contact dermatitis |
| L25.0 | Unspecified contact dermatitis due to cosmetics |
| L25.1 | Unspecified contact dermatitis due to drugs in contact with skin |
| L25.2 | Unspecified contact dermatitis due to dyes |
| L25.3 | Unspecified contact dermatitis due to other chemical products |
| L25.4 | Unspecified contact dermatitis due to food in contact with skin |
| L25.5 | Unspecified contact dermatitis due to plants, except food |
| L25.8 | Unspecified contact dermatitis due to other agents |
| L25.9 | Unspecified contact dermatitis, unspecified cause |
| L29.8 | Other pruritus |
| L29.9 | Pruritus, unspecified |
| L30.9 | Dermatitis, unspecified |
| R21 | Rash and other nonspecific skin eruption |
Formulary Reference Tool