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TOREMIFENE CITRATE (toremifene citrate)
- Metastatic breast carcinoma
toremifene 60 mg tablet
- 1 tablet (60 mg) by oral route once daily
60 mg tablet
- 1 tablet (60 mg) by oral route once daily
Metastatic breast carcinoma
- 1 tablet (60 mg) by oral route once daily
- adenovirus vac live type-4 & 7
- adenovirus vaccine live type-4
- adenovirus vaccine live type-7
- BCG vaccine, live (PF)
- flu vac,qval 2013-14 (2-49yrs)
- Flumist 2013-2014
- M-m-r Ii (pf)
- measles,mumps&rubella vacc(PF)
- measles,mumps,rub,varicel(PF)
- Proquad (pf)
- Rotateq Vaccine
- rotavirus vaccine live, penta
- typhoid vaccine
- varicella virus vacc live (PF)
- Varivax (pf)
- Vivotif Berna Vaccine
- yellow fever vaccine live (PF)
- Yf-vax (pf)
- Zostavax (pf)
- zoster vaccine live (PF)
Contraindicated
- Adasuve
- amiodarone
- amiodarone in dextrose,iso-osm
- amitriptyline
- amitriptyline-chlordiazepoxide
- Apokyn
- apomorphine
- arsenic trioxide
- artemether-lumefantrine
- Avelox
- Avelox Abc Pack
- Avelox In Nacl (iso-osmotic)
- B cplx-C-St.Johnwrt-K.&S.ginsg
- bedaquiline
- Belladonna-phenobarbital
- Betapace
- Betapace Af
- calcium-mag-B complex-D3-hrb61
- Caprelsa
- carbamazepine
- Carbatrol
- Celexa
- Cerebyx
- chloroquine phosphate
- chlorpromazine
- citalopram
- Coartem
- Cold & Flu Fighter
- Compazine
- Compro
- Cordarone
- Corvert
- Coumadin
- dasatinib
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- Dilantin
- Dilantin Extended
- Dilantin Infatabs
- Dilantin Kapseal
- Dilantin-125
- Diskets
- disopyramide
- dofetilide
- Dolophine
- Donnatal
- dronedarone
- droperidol
- Effexor Xr
- enzalutamide
- Epitol
- Equetro
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- escitalopram oxalate
- Fatigue Relief Complex
- fluphenazine decanoate
- fluphenazine HCl
- fosphenytoin
- granisetron
- granisetron (PF)
- Granisol
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- ibutilide fumarate
- Invega
- Invega Sustenna
- Invirase
- isoniazid-rifamp-pyrazinamide
- isradipine
- Jantoven
- Kaletra
- Levaquin
- Levaquin In 5 % Dextrose
- levofloxacin
- levofloxacin in D5W
- Lexapro
- lopinavir-ritonavir
- loxapine
- loxapine succinate
- Loxitane
- Luminal
- methadone
- Methadone Intensol
- Methadose
- moxifloxacin
- moxifloxacin in NaCl (iso-osm)
- Multaq
- Mycobutin
- Mysoline
- Nebupent
- Nexterone
- nilotinib
- norfloxacin
- Noroxin
- Norpace
- Norpace Cr
- ofloxacin
- ondansetron
- ondansetron HCl
- ondansetron HCl (PF)
- Orap
- Pacerone
- paliperidone
- paliperidone palmitate
- pasireotide
- Pentam
- pentamidine
- perphenazine
- perphenazine-amitriptyline
- Phenadoz
- Phenergan
- phenobarb-hyoscy-atropine-scop
- phenobarbital
- phenobarbital sodium
- Phenytek
- phenytoin
- phenytoin sodium
- phenytoin sodium extended
- pimozide
- primidone
- procainamide
- prochlorperazine
- prochlorperazine Edisylate
- prochlorperazine maleate
- promethazine
- Promethazine Vc
- Promethazine Vc-codeine
- promethazine-codeine
- promethazine-DM
- promethazine-phenyleph-codeine
- promethazine-phenylephrine
- Promethegan
- propafenone
- Qualaquin
- quinine sulfate
- rifabutin
- Rifadin
- Rifamate
- rifampin
- rifampin-isoniazid
- Rifater
- Rythmol
- Sancuso
- saquinavir mesylate
- Signifor
- Sirturo
- Sorine
- sotalol
- Sotalol Af
- Sprycel
- St. John's wort
- Tasigna
- Tegretol
- Tegretol Xr
- thioridazine
- Tikosyn
- trifluoperazine
- Trisenox
- vandetanib
- venlafaxine
- vit C-St. John wort-elder-hb30
- warfarin
- Women's Complex
- Xtandi
- Zofran
- Zofran Odt
- Zuplenz
Severe
Moderate
- Ablavar
- Advair Diskus
- Advair Hfa
- alfuzosin
- Aloxi
- amantadine HCl
- Anzemet
- Astagraf Xl
- azithromycin
- budesonide-formoterol
- Cardene Iv
- Cardene Iv In Dextrose
- Cardene Iv In Sodium Chloride
- Cardene Sr
- Cipro
- Cipro In D5W
- Cipro Xr
- ciprofloxacin
- ciprofloxacin (mixture)
- ciprofloxacin in D5W
- clozapine
- Clozaril
- Complera
- crizotinib
- dolasetron
- Dulera
- Edurant
- emtricitab-rilpivirine-tenofov
- Eovist
- eribulin
- ezogabine
- Fazaclo
- felbamate
- Felbatol
- fingolimod
- flecainide
- fluticasone-salmeterol
- Foradil Aerolizer
- formoterol fumarate
- foscarnet
- Foscavir
- gadofosveset trisodium
- gadoxetate
- Geodon
- Gilenya
- Halaven
- Hecoria
- indapamide
- Istodax
- lapatinib
- Levitra
- lithium carbonate
- lithium citrate
- Lithobid
- moexipril
- moexipril-hydrochlorothiazide
- mometasone-formoterol
- Nexavar
- nicardipine
- nicardipine in dextrose,iso-os
- nicardipine in NaCl (iso-os)
- Noxafil
- octreotide acetate
- palonosetron
- pazopanib
- Perforomist
- posaconazole
- Potiga
- Prograf
- quetiapine
- rilpivirine
- Risperdal
- Risperdal Consta
- Risperdal M-tab
- risperidone
- risperidone microspheres
- romidepsin
- salmeterol
- Sandostatin
- Sandostatin Lar Depot
- Serevent Diskus
- Seroquel
- Seroquel Xr
- Soltamox
- sorafenib
- sunitinib
- Sutent
- Symbicort
- tacrolimus
- tamoxifen
- telavancin
- tetrabenazine
- tizanidine
- Tykerb
- Uniretic
- Univasc
- Uroxatral
- vardenafil
- vemurafenib
- Versacloz
- Vibativ
- Votrient
- Xalkori
- Xenazine
- Zanaflex
- Zelboraf
- ziprasidone HCl
- ziprasidone mesylate
- Zithromax
- Zithromax Tri-pak
- Zithromax Z-pak
- Zmax
- Congenital long QT syndrome
- Lactating mother
- Torsades de pointes
Contraindicated
- Hypercalcemia
- Hypokalemia
- Hypomagnesemia
- Pregnancy
- Prolonged QT interval
- Thromboembolic disorder
Severe
Moderate
- Endometrial hyperplasia
- Leukopenia
- Thrombocytopenic disorder
TOREMIFENE CITRATE (toremifene citrate)
- Metastatic breast carcinoma
- Abnormal hepatic function tests
- Drug-induced hot flash
- Nausea
- Vaginal discharge
More Frequent
Severe
Less Severe
- Cataracts
- Disorder of cornea
- Endometrial hyperplasia
- Glaucoma
- Hyperbilirubinemia
- Hypercalcemia
- Visual field defect
- Abnormal vaginal bleeding
- Dizziness
- Dry eye
- Edema
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute myocardial infarction
- Drug-induced hepatitis
- Endometrial polyps
- Heart failure
- Jaundice
- Leukopenia
- Malignant neoplasm of the uterus
- Musculoskeletal pain
- Prolonged QT interval
- Pulmonary thromboembolism
- Steatosis of liver
- Thrombocytopenic disorder
- Thrombophlebitis
- Thrombotic disorder
Less Severe
- Constipation
- Depression
- Diplopia
- Dyschromia
- Dyspnea
- Hyperhidrosis
- Skin inflammation
- Tremor
- Vertigo
Contraindicated
None
Severe Precaution
Toremifene
Not indicated in pediatric patients.
- 1 Day – 18 Years
- Not indicated in pediatric patients.
Management or Monitoring Precaution
None
Toremifene
- Severity Level:
D
- Additional Notes:
Contraindicated
Toremifene
Animal studies suggest excretion occurs;Potential serious adver eff on infant
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Animal studies suggest excretion occurs;Potential serious adver eff on infant |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- Toremifene has caused very serious (possibly fatal) heart rhythm problems (QT prolongation in the EKG, torsades de pointes). Get medical help right away if any of these rare but serious side effects occur: fast/irregular heartbeat, seizures, severe dizziness, or fainting. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may affect the heart rhythm.<br /><br />Before using toremifene, tell your doctor or pharmacist of all the drugs you take (see also Drug Interaction section) and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death). Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using toremifene safely.
| Metastatic breast carcinoma | |
| C50 | Malignant neoplasm of breast |
| C50.1 | Malignant neoplasm of central portion of breast |
| C50.11 | Malignant neoplasm of central portion of breast, female |
| C50.111 | Malignant neoplasm of central portion of right female breast |
| C50.112 | Malignant neoplasm of central portion of left female breast |
| C50.119 | Malignant neoplasm of central portion of unspecified female breast |
| C50.12 | Malignant neoplasm of central portion of breast, male |
| C50.121 | Malignant neoplasm of central portion of right male breast |
| C50.122 | Malignant neoplasm of central portion of left male breast |
| C50.129 | Malignant neoplasm of central portion of unspecified male breast |
| C50.2 | Malignant neoplasm of upper-inner quadrant of breast |
| C50.21 | Malignant neoplasm of upper-inner quadrant of breast, female |
| C50.211 | Malignant neoplasm of upper-inner quadrant of right female breast |
| C50.212 | Malignant neoplasm of upper-inner quadrant of left female breast |
| C50.219 | Malignant neoplasm of upper-inner quadrant of unspecified female breast |
| C50.22 | Malignant neoplasm of upper-inner quadrant of breast, male |
| C50.221 | Malignant neoplasm of upper-inner quadrant of right male breast |
| C50.222 | Malignant neoplasm of upper-inner quadrant of left male breast |
| C50.229 | Malignant neoplasm of upper-inner quadrant of unspecified male breast |
| C50.3 | Malignant neoplasm of lower-inner quadrant of breast |
| C50.31 | Malignant neoplasm of lower-inner quadrant of breast, female |
| C50.311 | Malignant neoplasm of lower-inner quadrant of right female breast |
| C50.312 | Malignant neoplasm of lower-inner quadrant of left female breast |
| C50.319 | Malignant neoplasm of lower-inner quadrant of unspecified female breast |
| C50.32 | Malignant neoplasm of lower-inner quadrant of breast, male |
| C50.321 | Malignant neoplasm of lower-inner quadrant of right male breast |
| C50.322 | Malignant neoplasm of lower-inner quadrant of left male breast |
| C50.329 | Malignant neoplasm of lower-inner quadrant of unspecified male breast |
| C50.4 | Malignant neoplasm of upper-outer quadrant of breast |
| C50.41 | Malignant neoplasm of upper-outer quadrant of breast, female |
| C50.411 | Malignant neoplasm of upper-outer quadrant of right female breast |
| C50.412 | Malignant neoplasm of upper-outer quadrant of left female breast |
| C50.419 | Malignant neoplasm of upper-outer quadrant of unspecified female breast |
| C50.42 | Malignant neoplasm of upper-outer quadrant of breast, male |
| C50.421 | Malignant neoplasm of upper-outer quadrant of right male breast |
| C50.422 | Malignant neoplasm of upper-outer quadrant of left male breast |
| C50.429 | Malignant neoplasm of upper-outer quadrant of unspecified male breast |
| C50.5 | Malignant neoplasm of lower-outer quadrant of breast |
| C50.51 | Malignant neoplasm of lower-outer quadrant of breast, female |
| C50.511 | Malignant neoplasm of lower-outer quadrant of right female breast |
| C50.512 | Malignant neoplasm of lower-outer quadrant of left female breast |
| C50.519 | Malignant neoplasm of lower-outer quadrant of unspecified female breast |
| C50.52 | Malignant neoplasm of lower-outer quadrant of breast, male |
| C50.521 | Malignant neoplasm of lower-outer quadrant of right male breast |
| C50.522 | Malignant neoplasm of lower-outer quadrant of left male breast |
| C50.529 | Malignant neoplasm of lower-outer quadrant of unspecified male breast |
| C50.6 | Malignant neoplasm of axillary tail of breast |
| C50.61 | Malignant neoplasm of axillary tail of breast, female |
| C50.611 | Malignant neoplasm of axillary tail of right female breast |
| C50.612 | Malignant neoplasm of axillary tail of left female breast |
| C50.619 | Malignant neoplasm of axillary tail of unspecified female breast |
| C50.62 | Malignant neoplasm of axillary tail of breast, male |
| C50.621 | Malignant neoplasm of axillary tail of right male breast |
| C50.622 | Malignant neoplasm of axillary tail of left male breast |
| C50.629 | Malignant neoplasm of axillary tail of unspecified male breast |
| C50.8 | Malignant neoplasm of overlapping sites of breast |
| C50.81 | Malignant neoplasm of overlapping sites of breast, female |
| C50.811 | Malignant neoplasm of overlapping sites of right female breast |
| C50.812 | Malignant neoplasm of overlapping sites of left female breast |
| C50.819 | Malignant neoplasm of overlapping sites of unspecified female breast |
| C50.82 | Malignant neoplasm of overlapping sites of breast, male |
| C50.821 | Malignant neoplasm of overlapping sites of right male breast |
| C50.822 | Malignant neoplasm of overlapping sites of left male breast |
| C50.829 | Malignant neoplasm of overlapping sites of unspecified male breast |
| C50.9 | Malignant neoplasm of breast of unspecified site |
| C50.91 | Malignant neoplasm of breast of unspecified site, female |
| C50.911 | Malignant neoplasm of unspecified site of right female breast |
| C50.912 | Malignant neoplasm of unspecified site of left female breast |
| C50.919 | Malignant neoplasm of unspecified site of unspecified female breast |
| C50.92 | Malignant neoplasm of breast of unspecified site, male |
| C50.921 | Malignant neoplasm of unspecified site of right male breast |
| C50.922 | Malignant neoplasm of unspecified site of left male breast |
| C50.929 | Malignant neoplasm of unspecified site of unspecified male breast |
| 0-9 | A-Z |
|---|---|
| C50 | Malignant neoplasm of breast |
| C50.1 | Malignant neoplasm of central portion of breast |
| C50.11 | Malignant neoplasm of central portion of breast, female |
| C50.111 | Malignant neoplasm of central portion of right female breast |
| C50.112 | Malignant neoplasm of central portion of left female breast |
| C50.119 | Malignant neoplasm of central portion of unspecified female breast |
| C50.12 | Malignant neoplasm of central portion of breast, male |
| C50.121 | Malignant neoplasm of central portion of right male breast |
| C50.122 | Malignant neoplasm of central portion of left male breast |
| C50.129 | Malignant neoplasm of central portion of unspecified male breast |
| C50.2 | Malignant neoplasm of upper-inner quadrant of breast |
| C50.21 | Malignant neoplasm of upper-inner quadrant of breast, female |
| C50.211 | Malignant neoplasm of upper-inner quadrant of right female breast |
| C50.212 | Malignant neoplasm of upper-inner quadrant of left female breast |
| C50.219 | Malignant neoplasm of upper-inner quadrant of unspecified female breast |
| C50.22 | Malignant neoplasm of upper-inner quadrant of breast, male |
| C50.221 | Malignant neoplasm of upper-inner quadrant of right male breast |
| C50.222 | Malignant neoplasm of upper-inner quadrant of left male breast |
| C50.229 | Malignant neoplasm of upper-inner quadrant of unspecified male breast |
| C50.3 | Malignant neoplasm of lower-inner quadrant of breast |
| C50.31 | Malignant neoplasm of lower-inner quadrant of breast, female |
| C50.311 | Malignant neoplasm of lower-inner quadrant of right female breast |
| C50.312 | Malignant neoplasm of lower-inner quadrant of left female breast |
| C50.319 | Malignant neoplasm of lower-inner quadrant of unspecified female breast |
| C50.32 | Malignant neoplasm of lower-inner quadrant of breast, male |
| C50.321 | Malignant neoplasm of lower-inner quadrant of right male breast |
| C50.322 | Malignant neoplasm of lower-inner quadrant of left male breast |
| C50.329 | Malignant neoplasm of lower-inner quadrant of unspecified male breast |
| C50.4 | Malignant neoplasm of upper-outer quadrant of breast |
| C50.41 | Malignant neoplasm of upper-outer quadrant of breast, female |
| C50.411 | Malignant neoplasm of upper-outer quadrant of right female breast |
| C50.412 | Malignant neoplasm of upper-outer quadrant of left female breast |
| C50.419 | Malignant neoplasm of upper-outer quadrant of unspecified female breast |
| C50.42 | Malignant neoplasm of upper-outer quadrant of breast, male |
| C50.421 | Malignant neoplasm of upper-outer quadrant of right male breast |
| C50.422 | Malignant neoplasm of upper-outer quadrant of left male breast |
| C50.429 | Malignant neoplasm of upper-outer quadrant of unspecified male breast |
| C50.5 | Malignant neoplasm of lower-outer quadrant of breast |
| C50.51 | Malignant neoplasm of lower-outer quadrant of breast, female |
| C50.511 | Malignant neoplasm of lower-outer quadrant of right female breast |
| C50.512 | Malignant neoplasm of lower-outer quadrant of left female breast |
| C50.519 | Malignant neoplasm of lower-outer quadrant of unspecified female breast |
| C50.52 | Malignant neoplasm of lower-outer quadrant of breast, male |
| C50.521 | Malignant neoplasm of lower-outer quadrant of right male breast |
| C50.522 | Malignant neoplasm of lower-outer quadrant of left male breast |
| C50.529 | Malignant neoplasm of lower-outer quadrant of unspecified male breast |
| C50.6 | Malignant neoplasm of axillary tail of breast |
| C50.61 | Malignant neoplasm of axillary tail of breast, female |
| C50.611 | Malignant neoplasm of axillary tail of right female breast |
| C50.612 | Malignant neoplasm of axillary tail of left female breast |
| C50.619 | Malignant neoplasm of axillary tail of unspecified female breast |
| C50.62 | Malignant neoplasm of axillary tail of breast, male |
| C50.621 | Malignant neoplasm of axillary tail of right male breast |
| C50.622 | Malignant neoplasm of axillary tail of left male breast |
| C50.629 | Malignant neoplasm of axillary tail of unspecified male breast |
| C50.8 | Malignant neoplasm of overlapping sites of breast |
| C50.81 | Malignant neoplasm of overlapping sites of breast, female |
| C50.811 | Malignant neoplasm of overlapping sites of right female breast |
| C50.812 | Malignant neoplasm of overlapping sites of left female breast |
| C50.819 | Malignant neoplasm of overlapping sites of unspecified female breast |
| C50.82 | Malignant neoplasm of overlapping sites of breast, male |
| C50.821 | Malignant neoplasm of overlapping sites of right male breast |
| C50.822 | Malignant neoplasm of overlapping sites of left male breast |
| C50.829 | Malignant neoplasm of overlapping sites of unspecified male breast |
| C50.9 | Malignant neoplasm of breast of unspecified site |
| C50.91 | Malignant neoplasm of breast of unspecified site, female |
| C50.911 | Malignant neoplasm of unspecified site of right female breast |
| C50.912 | Malignant neoplasm of unspecified site of left female breast |
| C50.919 | Malignant neoplasm of unspecified site of unspecified female breast |
| C50.92 | Malignant neoplasm of breast of unspecified site, male |
| C50.921 | Malignant neoplasm of unspecified site of right male breast |
| C50.922 | Malignant neoplasm of unspecified site of left male breast |
| C50.929 | Malignant neoplasm of unspecified site of unspecified male breast |
Formulary Reference Tool