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M-CLEAR WC (GUAIFENESIN/CODEINE PHOSPHATE)
- Cough
6.3 mg-100 mg/5 mL oral liquid
- 15 milliliters by oral route every 4-6 hours as needed not to exceed 90 ml in 24Hrs
Cough
- 15 milliliters by oral route every 6 hours as needed
- 15 milliliters by oral route every 6 hours
- 15 milliliters by oral route every 4-6 hours as needed not to exceed 90 ml in 24Hrs
- 15 milliliters by oral route every 4 hours as needed not to exceed 90 ml in 24Hrs
- 15 milliliters by oral route every 4 hours not to exceed 90 ml in 24Hrs
- Depade
- naltrexone
- naltrexone microspheres
- Revia
- Vivitrol
Contraindicated
- None
Severe
Moderate
- Aplenzin
- Brisdelle
- Buprenex
- buprenorphine
- buprenorphine-naloxone
- Buproban
- bupropion HBr
- bupropion HCl
- butorphanol tartrate
- Butrans
- dextromethorphan-quinidine
- Fanatrex
- fluoxetine
- Forfivo Xl
- gabapentin
- gabapentin enacarbil
- Gralise
- Gralise 30-day Starter Pack
- Horizant
- nalbuphine
- Neurontin
- Nuedexta
- olanzapine-fluoxetine
- paroxetine HCl
- paroxetine mesylate
- Paxil
- Paxil Cr
- Pexeva
- Prozac
- Prozac Weekly
- quinidine gluconate
- quinidine sulfate
- Sarafem
- Suboxone
- Symbyax
- Wellbutrin
- Wellbutrin Sr
- Wellbutrin Xl
- Zubsolv
- Zyban
- Adenoidectomy in pediatric patient
- Lactating mother
- Respiratory depression
- Sleep apnea
- Tonsillectomy in pediatric patient
Contraindicated
- Acute asthma attack
- Acute pancreatitis
- Asthma
- Chronic obstructive pulmonary disease
- CYp2d6 poor metabolizer
- CYp2d6 ultrarapid metabolizer
- Drug abuse
- Gastrointestinal obstruction
- History of opioid overdose
- Intracranial hypertension
- Kidney disease with likely reduction in GFR
- Obstructive sleep apnea syndrome
- Shock
- Systemic mastocytosis
Severe
Moderate
- Adrenal cortical insufficiency
- Alcohol intoxication
- Biliary tract disorder
- Constipation
- Cor pulmonale
- Debilitation
- Hypotension
- No disease contraindications
- Seizure disorder
- Severe hepatic disease
- Untreated hypothyroidism
- Urinary retention
M-CLEAR WC (GUAIFENESIN/CODEINE PHOSPHATE)
- Cough
- None
- Abdominal pain with cramps
- Constipation
- Drowsy
- Nausea
- Sedation
More Frequent
Severe
Less Severe
- Atelectasis
- CNS depression
- Dyspnea
- Orthostatic hypotension
- Respiratory depression
- Acute confusion
- Anorexia
- Dizziness
- Dysphoric mood
- General weakness
- Headache disorder
- Hyperhidrosis
- Hypotension
- Nervousness
- Oliguria
- Palpitations
- Pruritus of skin
- Skin rash
- Syncope
- Urticaria
- Visual changes
- Vomiting
- Xerostomia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute respiratory insufficiency
- Adrenal cortical insufficiency
- Anaphylaxis
- Androgen deficiency
- Bradycardia
- Cardiac arrest
- Circulatory depression
- Ileus
- Opioid dependence
- Pancreatitis
- Seizure disorder
- Shock
- Sleep apnea
Less Severe
- Biliary spasm
- Diarrhea
- Erectile dysfunction
- Euphoria
- Fatigue
- Flushing
- Gastrointestinal irritation
- Infertility
- Insomnia
- Libido changes
- Nausea
- Symptoms of anxiety
- Vertigo
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Codeine
- Severity Level:
C
- Additional Notes: Neonatal withdrawal/resp.depress. w/chronic or high dose; small teratogenic risk
Guaifenesin
- Severity Level:
C
- Additional Notes:
Contraindicated
Codeine
Cns/respiratory depression,apnea possible;Caution w/ fast cyp2D6 metabolizer
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Excreted | Drug shown to have adverse effect | Cns/respiratory depression,apnea possible;Caution w/ fast cyp2D6 metabolizer |
Precaution Exists
Guaifenesin
Insufficient data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Cough | |
| R05 | Cough |
| 0-9 | A-Z |
|---|---|
| R05 | Cough |
Formulary Reference Tool