BUTALB-CAFF-ACETAMINOPH-CODEIN (BUTALBITAL/ACETAMINOPHEN/CAFFEINE/CODEINE PHOS)
- Tension-type headache
- Butalbital-acetaminophen-caffeine-codeine Capsule
- Butalbital-acetaminophen-caffeine-codeine Cap
- By Indication
butalbital 50 mg-acetaminophen 300 mg-caffeine 40 mg-codeine 30 mg cap
- 1 - 2 capsules by oral route every 4 hours as needed not to exceed 6 capsules per 24Hrs
butalbital 50 mg-acetaminophen 325 mg-caffeine 40 mg-codeine 30 mg cap
- 1 capsule by oral route every 4 hours as needed not to exceed 6 capsules per 24Hrs
butalbital 50 mg-acetaminophen 300 mg-caffeine 40 mg-codeine 30 mg cap
- 1 - 2 capsules by oral route every 4 hours as needed not to exceed 6 capsules per 24Hrs
butalbital 50 mg-acetaminophen 325 mg-caffeine 40 mg-codeine 30 mg cap
- 1 capsule by oral route every 4 hours as needed not to exceed 6 capsules per 24Hrs
Tension-type headache
- 1 capsule by oral route every 4 hours as needed not to exceed 6 capsules per 24Hrs
- 2 capsules by oral route every 4 hours as needed not to exceed 6Capsules per 24Hrs
- 1 - 2 capsules by oral route every 4 hours as needed not to exceed 6 capsules per 24Hrs
- Depade
- dipyridamole
- naltrexone
- naltrexone microspheres
- Revia
- sodium oxybate
- Vivitrol
- Xyrem
Contraindicated
- Acid Reducer (cimetidine)
- Acid Relief (cimetidine)
- Adenocard
- Adenoscan
- adenosine
- adenosine (diagnostic)
- Afinitor
- Afinitor Disperz
- Altavera (28)
- Alyacen 1/35 (28)
- Alyacen 7/7/7 (28)
- Amethia
- Amethia Lo
- Amethyst
- Apri
- Aranelle (28)
- Astagraf Xl
- Aubra
- Aviane
- Azurette (28)
- Balziva (28)
- Beyaz
- Brevicon (28)
- Briellyn
- Camila
- Camrese
- Camrese Lo
- Caziant (28)
- Chateal
- cimetidine
- Coumadin
- Cryselle (28)
- Cyclafem 1/35 (28)
- Cyclafem 7/7/7 (28)
- Cyclessa (28)
- cyclosporine
- cyclosporine modified
- Dasetta 1/35 (28)
- Dasetta 7/7/7 (28)
- Daysee
- desog-e.estradiol/e.estradiol
- Desogen
- desogestrel-ethinyl estradiol
- drospirenone-e.estradiol-lm.FA
- drospirenone-ethinyl estradiol
- Elinest
- Emoquette
- Enpresse
- Enskyce
- Errin
- Estarylla
- estradiol valerate-dienogest
- Estrostep Fe-28
- ethynodiol diac-eth estradiol
- etonogestrel
- etonogestrel-ethinyl estradiol
- everolimus
- Falmina (28)
- Femcon Fe
- Generess Fe
- Gengraf
- Gianvi (28)
- Gildagia
- Gildess
- Gildess Fe
- Heartburn Relief
- Heather
- Hecoria
- Introvale
- Jantoven
- Jencycla
- Jolessa
- Jolivette
- Junel 1.5/30 (21)
- Junel 1/20 (21)
- Junel Fe 1.5/30 (28)
- Junel Fe 1/20 (28)
- Kariva (28)
- Kelnor 1/35 (28)
- Kurvelo
- L norgest&E estradiol-E estrad
- Larin 1/20 (21)
- Larin Fe
- Leena 28
- Lessina
- Levonest (28)
- levonorg-eth estrad triphasic
- levonorgestrel
- levonorgestrel-ethinyl estrad
- Levora 0.15/30 (28)
- Levora-28
- Lexiscan
- Lo Loestrin Fe
- Loestrin 1.5/30 (21)
- Loestrin 1/20 (21)
- Loestrin Fe 1.5/30 (28)
- Loestrin Fe 1/20 (28)
- Lomedia 24 Fe
- Loryna (28)
- Loseasonique
- Low-ogestrel (28)
- Lutera (28)
- Lyza
- Marlissa
- Microgestin 1.5/30 (21)
- Microgestin 1/20 (21)
- Microgestin Fe 1.5/30 (28)
- Microgestin Fe 1/20 (28)
- Minastrin 24 Fe
- Mircette (28)
- Mirena
- Modicon (28)
- Mono-linyah
- Mononessa (28)
- My Way
- Myzilra
- Natazia
- Necon 0.5/35 (28)
- Necon 1/35 (28)
- Necon 1/50 (28)
- Necon 10/11 (28)
- Necon 7/7/7 (28)
- Neoral
- Nexplanon
- Next Choice One Dose
- Nor-qd
- Nora-be
- norelgestrom-ethinyl estradiol
- noreth-ethinyl estradiol-iron
- norethin-e.estradiol triphasic
- norethin-eth estrad biphasic
- norethindrone (contraceptive)
- norethindrone ac-eth estradiol
- norethindrone-e.estradiol-iron
- norethindrone-ethin estradiol
- norethindrone-mestranol
- norgestimate-ethinyl estradiol
- norgestrel-ethinyl estradiol
- Norinyl 1+35 (28)
- Norinyl 1+50 (28)
- Nortrel 0.5/35 (28)
- Nortrel 1/35 (21)
- Nortrel 1/35 (28)
- Nortrel 7/7/7 (28)
- Nuvaring
- Ocella
- Ogestrel (28)
- Orsythia
- Ortho Evra
- Ortho Micronor
- Ortho Tri-cyclen (28)
- Ortho Tri-cyclen Lo (28)
- Ortho-cept (28)
- Ortho-cyclen (28)
- Ortho-novum 1/35 (28)
- Ortho-novum 7/7/7 (28)
- Ovcon-35 (28)
- Philith
- Pimtrea (28)
- Pirmella
- Plan B One-step
- Portia
- Previfem
- Prograf
- Quartette
- Quasense
- quetiapine
- Rapamune
- Reclipsen (28)
- regadenoson
- Safyral
- Samsca
- Sandimmune
- Seasonique
- Seroquel Xr
- sirolimus
- Skyla
- Sprintec (28)
- Sronyx
- Syeda
- tacrolimus
- Tagamet Hb
- temsirolimus
- Tilia Fe
- tolvaptan
- Torisel
- Tri-estarylla
- Tri-legest Fe
- Tri-linyah
- Tri-norinyl (28)
- Tri-previfem (28)
- Tri-sprintec (28)
- Trinessa (28)
- Trivora (28)
- Velivet Triphasic Regimen (28)
- Vestura (28)
- Viorele (28)
- Vyfemla (28)
- warfarin
- Wera (28)
- Wymzya Fe
- Yasmin (28)
- Yaz 28
- Zarah
- Zenchent (28)
- Zenchent Fe
- Zeosa
- Zortress
- Zovia 1/35E (28)
- Zovia 1/50E (28)
Severe
Moderate
- A-hydrocort
- A-methapred
- Abilify
- Abilify Discmelt
- Abilify Maintena
- acebutolol
- Activella
- Adasuve
- Adoxa
- Alora
- aminophylline
- Angeliq
- Anucort-hc
- Anusol-hc
- Aplenzin
- aripiprazole
- Aristospan Intra-articular
- Aristospan Intralesional
- Avidoxy
- betamethasone acet & sod phos
- betaxolol
- Brisdelle
- budesonide
- Buprenex
- buprenorphine
- buprenorphine-naloxone
- Buproban
- bupropion HBr
- bupropion HCl
- butorphanol tartrate
- Butrans
- Celestone Soluspan
- Cenestin
- chlorpromazine
- Climara
- Climara Pro
- Colocort
- Combipatch
- Compazine
- Compro
- conj estrogens-bazedoxifene
- conjugated estrogens
- Cortef
- Cortenema
- Cortifoam
- cortisone
- Covaryx
- Covaryx H.s.
- Delestrogen
- Depo-estradiol
- Depo-medrol
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- dextromethorphan-quinidine
- Divigel
- Doryx
- Doxy-100
- doxycycline calcium
- doxycycline hyclate
- doxycycline monohydrate
- drospirenone-estradiol
- Duavee
- Dutoprol
- Eemt
- Eemt Hs
- Elestrin
- Elixophyllin
- Enjuvia
- Entocort Ec
- esterified estrogens
- Estrace
- estradiol
- estradiol acetate
- estradiol cypionate
- Estradiol Transdermal Patch
- estradiol valerate
- estradiol-levonorgestrel
- estradiol-norethindrone acet
- estradiol-norgestimate
- Estrasorb
- Estring
- Estrogel
- estrogens-methyltestosterone
- estropipate
- Evamist
- Ez Use Joint-tunnel-trigger
- Fanatrex
- felodipine
- Femhrt Low Dose
- Femring
- First-duke's
- First-mary's Mouthwash
- Flagyl
- Flagyl Er
- Flo-pred
- fludrocortisone
- fluoxetine
- fluphenazine decanoate
- fluphenazine HCl
- fluvoxamine
- Forfivo Xl
- gabapentin
- gabapentin enacarbil
- Gralise
- Gralise 30-day Starter Pack
- Grx Hicort 25
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- Hemril-30
- Horizant
- hydrocortisone
- hydrocortisone acetate
- hydrocortisone sod succ (PF)
- hydrocortisone sod succinate
- Inderal La
- Inderal Xl
- Innopran Xl
- isoniazid
- isoniazid-rifamp-pyrazinamide
- Jinteli
- Kenalog
- lithium carbonate
- lithium citrate
- Lithobid
- Lopressor
- Lopressor Hct
- loxapine
- loxapine succinate
- Loxitane
- Luvox Cr
- Medrol
- Medrol (pak)
- Menest
- Menostar
- methylprednisolone
- methylprednisolone acetate
- methylprednisolone sod suc(PF)
- methylprednisolone sodium succ
- methylprednisolone-bupivacaine
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- Metro I.v.
- Metrogel Vaginal
- metronidazole
- metronidazole in NaCl (iso-os)
- Millipred
- Millipred Dp
- Mimvey
- Minivelle
- Monodox
- Morgidox
- nalbuphine
- Neurontin
- Nuedexta
- nystatin-hydrocortisone-diphen
- nystatin-TCN-HC-diphenhydramin
- Ogen 2.5
- olanzapine-fluoxetine
- Oracea
- Orapred
- Orapred Odt
- paroxetine HCl
- paroxetine mesylate
- Paxil
- Paxil Cr
- Pediapred
- perphenazine
- perphenazine-amitriptyline
- Pexeva
- Phenadoz
- Phenergan
- Physicians Ez Use M-pred
- prednisolone
- prednisolone acetate
- prednisolone sodium phosphate
- prednisone
- Prednisone Intensol
- Prefest
- Premarin
- prochlorperazine
- prochlorperazine Edisylate
- prochlorperazine maleate
- Proctocort
- promethazine
- Promethazine Vc
- Promethazine Vc-codeine
- promethazine-codeine
- promethazine-DM
- promethazine-phenyleph-codeine
- promethazine-phenylephrine
- Promethegan
- propranolol
- propranolol-hydrochlorothiazid
- Prozac
- Prozac Weekly
- quinidine gluconate
- quinidine sulfate
- Rayos
- Rectacort-hc
- Rifamate
- rifampin-isoniazid
- Rifater
- Risperdal
- Risperdal Consta
- Risperdal M-tab
- risperidone
- risperidone microspheres
- Sarafem
- Sectral
- Seroquel
- Solu-cortef
- Solu-cortef (pf)
- Solu-medrol
- Solu-medrol (pf)
- Suboxone
- Symbyax
- synthetic conj estrogens A
- synthetic conj estrogens B
- Theo-24
- Theochron
- theophylline
- theophylline in dextrose 5 %
- thioridazine
- Toprol Xl
- triamcinolone acetonide
- triamcinolone hexacetonide
- triamcinolone-lidocaine
- trifluoperazine
- Uceris
- Vagifem
- Vandazole
- Veripred 20
- Vibramycin
- Vivelle-dot
- Wellbutrin
- Wellbutrin Sr
- Wellbutrin Xl
- Zubsolv
- Zyban
- 30 day risk period post-myocardial infarction
- Acetaminophen overdose
- Acute asthma attack
- Acute hepatic failure
- Acute hepatitis C
- Adenoidectomy in pediatric patient
- Alcoholism
- Lactating mother
- Porphyria
- Respiratory depression
- Sleep apnea
- Tonsillectomy in pediatric patient
Contraindicated
- Acute asthma attack
- Acute pancreatitis
- Acute respiratory insufficiency
- Asthma
- Chronic obstructive pulmonary disease
- CYp2d6 poor metabolizer
- CYp2d6 ultrarapid metabolizer
- Depression
- Disease of liver
- Drug abuse
- Gastrointestinal obstruction
- Hepatic coma
- Hepatic encephalopathy
- History of opioid overdose
- Hyperammonemia
- Intracranial hypertension
- Kidney disease with likely reduction in GFR
- Necrotizing enterocolitis
- Obstructive sleep apnea syndrome
- Peptic ulcer
- Protein-calorie malnutrition
- Severe renal impairment
- Shock
- Suicidal ideation
- Systemic mastocytosis
Severe
Moderate
- Adrenal cortical insufficiency
- Alcohol intoxication
- Anemia
- Biliary tract disorder
- Cardiac arrhythmia
- Complex sleep behavior
- Constipation
- Cor pulmonale
- Debilitation
- Disease of liver
- Hyperkinesis
- Hypertension
- Hypotension
- Insomnia
- Kidney disease with reduction in GFR
- Neutropenic disorder
- Renal disease with moderate to severe impairment
- Seizure disorder
- Severe hepatic disease
- Thrombocytopenic disorder
- Untreated hypothyroidism
- Urinary retention
BUTALB-CAFF-ACETAMINOPH-CODEIN (BUTALBITAL/ACETAMINOPHEN/CAFFEINE/CODEINE PHOS)
- Tension-type headache
- None
- Abdominal pain with cramps
- Constipation
- Dizziness
- Drowsy
- Gastrointestinal irritation
- Insomnia
- Nausea
- Nervousness
- Sedation
More Frequent
Severe
Less Severe
- Abnormal hepatic function tests
- Acute confusion
- Atelectasis
- CNS depression
- Dyspnea
- Excitement
- Lethargy
- Orthostatic hypotension
- Respiratory depression
- Acute confusion
- Anorexia
- Constipation
- Depression
- Dizziness
- Dysphoric mood
- Excitement
- General weakness
- Headache disorder
- Hyperhidrosis
- Hypotension
- Insomnia
- Irritability
- Nausea
- Nervousness
- Nightmares
- Oliguria
- Palpitations
- Pruritus of skin
- Skin rash
- Symptoms of anxiety
- Syncope
- Urticaria
- Vertigo
- Visual changes
- Vomiting
- Xerostomia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Accidental fall
- Acute generalized exanthematous pustulosis
- Acute hepatic failure
- Acute respiratory insufficiency
- Adrenal cortical insufficiency
- Agranulocytosis
- Allergic dermatitis
- Altered consciousness
- Anaphylaxis
- Androgen deficiency
- Angioedema
- Apnea
- Bradycardia
- Cardiac arrest
- Circulatory depression
- Drug-induced hepatitis
- Dyspnea
- Exfoliative dermatitis
- Extrasystoles
- Hallucinations
- Hypersensitivity drug reaction
- Hypotension
- Hypoventilation
- Ileus
- Laryngeal edema
- Leukopenia
- Maculopapular rash
- Megaloblastic anemia
- Memory impairment
- Neutropenic disorder
- Opioid dependence
- Osteopenia
- Pancreatitis
- Psychiatric disorder
- Rickets
- Seizure disorder
- Shock
- Skin rash
- Sleep apnea
- Stevens-johnson syndrome
- Throat constriction
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
- Urticaria
- Wheezing
Less Severe
- Agitation
- Ataxia
- Biliary spasm
- CNS depression
- Complex sleep behavior
- Diarrhea
- Disturbance in thinking
- Drug dependence
- Erectile dysfunction
- Erythema
- Euphoria
- Fatigue
- Flushing
- Gastrointestinal irritation
- Hyperesthesia
- Hyperglycemia
- Hyperkinesis
- Infertility
- Insomnia
- Irritability
- Libido changes
- Medication overuse headache
- Nausea
- Nephrotoxicity
- Scotomata
- Skin rash
- Symptoms of anxiety
- Tachycardia
- Tinnitus
- Tremor
- Urticaria
- Vertigo
- Vomiting
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
None
Acetaminophen
- Severity Level:
2
- Additional Notes: Available data suggest no known risk; otc product, no fda pregnancy warnings
Butalbital
- Severity Level:
C
- Additional Notes: Case report of neonatal withdrawal seizures with butalbital combo product
Caffeine
- Severity Level:
C
- Additional Notes: Reports of miscarriage,poor fetal growth possibly assoc w/high doses of caffeine
Codeine
- Severity Level:
C
- Additional Notes: Neonatal withdrawal/resp.depress. w/chronic or high dose; small teratogenic risk
Contraindicated
Codeine
Cns/respiratory depression,apnea possible;Caution w/ fast cyp2D6 metabolizer
General | Excretion Potential | Effect on Infant | Notes |
Drug should not be given to breast feeding mothers | Excreted | Drug shown to have adverse effect | Cns/respiratory depression,apnea possible;Caution w/ fast cyp2D6 metabolizer |
Precaution Exists
Butalbital
Possibility of central nervous system depression in nursing infant.
High doses may cause hyperactivity and wakefulness in infant.
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Drug shown to have adverse effect | Possibility of central nervous system depression in nursing infant. |
Caffeine
Possibility of central nervous system depression in nursing infant.
High doses may cause hyperactivity and wakefulness in infant.
General | Excretion Potential | Effect on Infant | Notes |
Evaluate use carefully | Excreted | Drug shown to have adverse effect | High doses may cause hyperactivity and wakefulness in infant. |
No Known Risk
Acetaminophen
Low levels excreted with low risk for adverse effects in infant
General | Excretion Potential | Effect on Infant | Notes |
No known risks; does not adversely affect lactation | Excreted | No adverse effect | Low levels excreted with low risk for adverse effects in infant |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- Codeine has a risk for abuse and addiction, which can lead to overdose and death. Codeine may also cause severe, possibly fatal, breathing problems. To lower your risk, your doctor should have you take the smallest dose of codeine that works, and take it for the shortest possible time.<br /><br />See also How to Use section for more information about addiction. The risk for severe breathing problems is higher when you start this medication and after a dose increase, or if you take the wrong dose/strength. Taking this medication with alcohol or other drugs that can cause drowsiness or breathing problems may cause very serious side effects, including death.<br /><br />Also, other medications can affect the removal of codeine from your body, which may affect how codeine works. Be sure you know how to take this medication and what other drugs you should avoid taking with it. See also Drug Interactions section.<br /><br />Get medical help right away if any of these very serious side effects occur: slow/shallow breathing, unusual lightheadedness, severe drowsiness/dizziness, difficulty waking up. Keep this medicine in a safe place to prevent theft, misuse, or abuse. If someone accidentally swallows this medication, get medical help right away.<br /><br /> One ingredient in this product is acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day.<br /><br />People with liver problems and children should take less acetaminophen. Ask your doctor or pharmacist how much acetaminophen is safe to take. Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first.<br /><br />Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough-and-cold products). Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. Get medical help right away if you take too much acetaminophen (overdose), even if you feel well.<br /><br />Overdose symptoms may include nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, yellowing eyes/skin, and dark urine. Daily alcohol use, especially when combined with acetaminophen, may damage your liver. Avoid alcohol.<br /><br /> Before using this medication, women of childbearing age should talk with their doctor(s) about the risks and benefits. Tell your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed.<br /><br />It may slightly increase the risk of birth defects if used during the first two months of pregnancy. Also, using it for a long time or in high doses near the expected delivery date may harm the unborn baby. To lessen the risk, take the smallest effective dose for the shortest possible time.<br /><br /> Babies born to mothers who use this drug for a long time may develop severe (possibly fatal) withdrawal symptoms. Tell the doctor right away if you notice any symptoms in your newborn baby such as crying that doesn't stop, slow/shallow breathing, irritability, shaking, vomiting, diarrhea, poor feeding, or difficulty gaining weight. Children younger than 12 years should not use products that contain codeine.<br /><br />Children between 12 and 18 years old should not use codeine after certain surgeries (including tonsil/adenoid removal). Also, codeine use is not recommended for children between 12 and 18 years old who are obese or have breathing problems. Some children are more sensitive to codeine and have had very serious (rarely fatal) breathing problems such as slow/shallow breathing (see also Side Effects section). Talk with your doctor or pharmacist about the risks and benefits of this medication.
Tension-type headache | |
G44.2 | Tension-type headache |
G44.20 | Tension-type headache, unspecified |
G44.201 | Tension-type headache, unspecified, intractable |
G44.209 | Tension-type headache, unspecified, not intractable |
G44.21 | Episodic tension-type headache |
G44.211 | Episodic tension-type headache, intractable |
G44.219 | Episodic tension-type headache, not intractable |
G44.22 | Chronic tension-type headache |
G44.221 | Chronic tension-type headache, intractable |
G44.229 | Chronic tension-type headache, not intractable |
0-9 | A-Z |
---|---|
G44.2 | Tension-type headache |
G44.20 | Tension-type headache, unspecified |
G44.201 | Tension-type headache, unspecified, intractable |
G44.209 | Tension-type headache, unspecified, not intractable |
G44.21 | Episodic tension-type headache |
G44.211 | Episodic tension-type headache, intractable |
G44.219 | Episodic tension-type headache, not intractable |
G44.22 | Chronic tension-type headache |
G44.221 | Chronic tension-type headache, intractable |
G44.229 | Chronic tension-type headache, not intractable |