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SINUS RELIEF (PHENYLEPHRINE HCL/ACETAMINOPHEN)
- Nasal congestion
- Sinus headache
- Rhinorrhea
- Wal-phed Pe Sinus Headache Tablet
- Suphedrine Pe Sinus Headache Tablet
- Sudafed Pe Pressure+pain Tablet
- Sinus Relief (non-drowsy) Tablet
- Sinus Pain-pressure (pe) Tablet
- Sinus Pain Relief Tablet
- Sinus Maximum Strength Tablet
- Sinus Headache Pe Tablet
- Sinus Congestion And Pain Tablet
- Sinus Congestion & Pain Tablet
- Mapap Sinus Maximum Strength (pe) Tablet
- Acetaminophen Congestion-pain Tablet
5 mg-325 mg tablet
- Dosage information is not available
Sinus Headache 5 mg-325 mg tablet
- Dosage information is not available
Sudafed PE Pressure-Pain 5 mg-325 mg tablet
- Dosage information is not available
(Non-Drowsy) 5 mg-325 mg tablet
- Dosage information is not available
Sinus Pain-Pressure (PE) 5 mg-325 mg tablet
- Dosage information is not available
Sinus Pain-Pressure (PE) 5 mg-500 mg tablet
- Dosage information is not available
5 mg-325 mg tablet
- Dosage information is not available
5 mg-325 mg tablet
- Dosage information is not available
5 mg-325 mg tablet
- Dosage information is not available
Sinus Headache PE 5 mg-325 mg tablet
- Dosage information is not available
Sinus Congestion and Pain 5 mg-325 mg tablet
- Dosage information is not available
Sinus Congestion and Pain 5 mg-325 mg tablet
- Dosage information is not available
Maximum Strength (PE) 5 mg-325 mg tablet
- Dosage information is not available
5 mg-325 mg tablet
- Dosage information is not available
- tranylcypromine
- procarbazine
- phenelzine
- Parnate
- Nardil
- methylene blue (antidote)
- Matulane
- Marplan
- isocarboxazid
Contraindicated
- Zyvox
- Zelapar
- Ultane
- Terrell
- Sojourn
- sevoflurane
- selegiline HCl
- rasagiline
- Parlodel
- Migranal
- Migergot
- methylergonovine
- linezolid
- isoflurane
- Forane
- ergotamine-caffeine
- ergotamine tartrate
- Ergomar
- ergoloid
- enflurane
- Eldepryl
- dihydroergotamine
- D.h.e.45
- Cycloset
- Compound 347
- Cafergot
- cabergoline
- bromocriptine
- Azilect
Severe
Moderate
- warfarin
- Rifater
- rifampin-isoniazid
- Rifamate
- reserpine
- methyldopate
- methyldopa-hydrochlorothiazide
- methyldopa
- Jantoven
- isoniazid-rifamp-pyrazinamide
- isoniazid
- Coumadin
- Acetaminophen overdose
- Acute hepatic failure
- Acute hepatitis C
- Acute myocardial infarction
- Arterial thrombosis
- Severe uncontrolled hypertension
- Ventricular tachycardia
Contraindicated
- Acute hepatitis
- Acute pancreatitis
- Benign prostatic hyperplasia
- Bradycardia
- Coronary artery disease
- Disease of liver
- Hypertension
- Hyperthyroidism
- Incomplete AV heart block
- Protein-calorie malnutrition
- Severe arteriosclerotic vascular disease
- Severe renal impairment
- Shock
Severe
Moderate
- Acidosis
- Chronic heart failure
- Hypoxia
SINUS RELIEF (PHENYLEPHRINE HCL/ACETAMINOPHEN)
- Nasal congestion
- Sinus headache
- Rhinorrhea
- None
- None
More Frequent
Severe
Less Severe
- Abnormal hepatic function tests
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute generalized exanthematous pustulosis
- Acute hepatic failure
- Agranulocytosis
- Allergic dermatitis
- Angioedema
- Cardiac arrhythmia
- Dizziness
- Drug-induced hepatitis
- Headache disorder
- Hyperhidrosis
- Insomnia
- Laryngeal edema
- Leukopenia
- Maculopapular rash
- Nervousness
- Neutropenic disorder
- Pallor
- Stevens-johnson syndrome
- Tachycardia
- Thrombocytopenic disorder
- Toxic epidermal necrolysis
- Tremor
Less Severe
- Erythema
- Medication overuse headache
- Skin rash
- Urticaria
Contraindicated
Phenylephrine (Oral,Rectal)
Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 1 Day – 6 Years
- 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
Severe Precaution
None
Management or Monitoring Precaution
Acetaminophen (oral,rectal)
Use weight based dosing in children less than 12 years.
- 1 Day – 12 Years
- Use weight based dosing in children less than 12 years.
Acetaminophen
- Severity Level:
2
- Additional Notes: Available data suggest no known risk; otc product, no fda pregnancy warnings
Phenylephrine
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Phenylephrine
Oral bioavailability low; infant exposure may be minimal
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Oral bioavailability low; infant exposure may be minimal |
No Known Risk
Acetaminophen
Low levels excreted with low risk for adverse effects in infant
| General | Excretion Potential | Effect on Infant | Notes |
| No known risks; does not adversely affect lactation | Excreted | No adverse effect | Low levels excreted with low risk for adverse effects in infant |
Contraindicated
None
Precaution Exists
Acetaminophen (oral,rectal)
Hepatic-Elderly may be more susceptible to hepatotoxicity. Strict adherence to a maximum daily dose is recommended, and the maximum dose recommendation varies between 3000-3800 mg depending on strength used and source of the recommendation.
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | Y | N | N | N | N |
BEERS: N HEDIS: N STOPP: N
Phenylephrine
Hepatic-Elderly may be more susceptible to hepatotoxicity. Strict adherence to a maximum daily dose is recommended, and the maximum dose recommendation varies between 3000-3800 mg depending on strength used and source of the recommendation.
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Nasal congestion | |
| R09.81 | Nasal congestion |
| Rhinorrhea | |
| R09.82 | Postnasal drip |
| Sinus headache | |
| R51 | Headache |
| 0-9 | A-Z |
|---|---|
| R09.81 | Nasal congestion |
| R09.82 | Postnasal drip |
| R51 | Headache |
Formulary Reference Tool