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TOLAK (FLUOROURACIL)
- Actinic keratosis
4 % topical cream
- Apply a sufficient amount to cover the lesions in the affected area(s) by topical route once daily for 4 weeks
Actinic keratosis
- Apply a sufficient amount to cover the lesions in the affected area(s) by topical route once daily
- Apply a sufficient amount to cover the lesions in the affected area(s) by topical route once daily for 4 weeks
- None
Contraindicated
- None
Severe
Moderate
- None
- Dihydropyrimidine dehydrogenase deficiency
- Lactating mother
- Pregnancy
Contraindicated
- None
Severe
Moderate
- None
TOLAK (FLUOROURACIL)
- Actinic keratosis
- Dermatitis due to topical drug
- Pruritus of skin
- Skin rash
- Paresthesia
- Skin photosensitivity
More Frequent
Severe
Less Severe
- None
- Pain
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- None
Less Severe
- Dyschromia
- Eye tearing
- Skin scaling
- Skin thickening
- Telangiectasia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Fluorouracil (Topical)
Safety and efficacy not established. Actinic keratosis rare in pediatrics.
- 1 Day – 18 Years
- Safety and efficacy not established. Actinic keratosis rare in pediatrics.
Fluorouracil (topical)
- Severity Level:
X
- Additional Notes:
Contraindicated
Fluorouracil (topical)
Some systemic absorption with topical use;Potential severe adverse effects.
| General | Excretion Potential | Effect on Infant | Notes |
| Drug should not be given to breast feeding mothers | Unknown | Not known; no or inclusive data | Some systemic absorption with topical use;Potential severe adverse effects. |
Precaution Exists
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Actinic keratosis | |
| L57.0 | Actinic keratosis |
| 0-9 | A-Z |
|---|---|
| L57.0 | Actinic keratosis |
Formulary Reference Tool