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MYCOBUTIN (RIFABUTIN)
- Prevention of mycobacterium avium complex disease
150 mg capsule
- 2 capsules (300 mg) by oral route once daily
150 mg capsule
- 2 capsules (300 mg) by oral route once daily
Prevention of mycobacterium avium complex disease
- 1 capsule (150 mg) by oral route 2 times per day with food
- 1 capsule (150 mg) by oral route every 12 hours with food
- 2 capsules (300 mg) by oral route once daily
- Adalat Cc
- Afeditab Cr
- artemether-lumefantrine
- Coartem
- delavirdine
- Latuda
- lurasidone
- Nifedical Xl
- nifedipine
- Procardia
- Procardia Xl
- Rescriptor
- typhoid vaccine
- Vfend
- Vfend Iv
- Vivotif Berna Vaccine
- voriconazole
Contraindicated
- Activella
- Afinitor
- Afinitor Disperz
- Alora
- Altavera (28)
- Alyacen 1/35 (28)
- Alyacen 7/7/7 (28)
- Amethia
- Amethia Lo
- Amethyst
- aminophylline
- Angeliq
- aprepitant
- Apri
- Aranelle (28)
- Astagraf Xl
- atazanavir
- Aubra
- Aviane
- axitinib
- Azurette (28)
- Balziva (28)
- BCG live
- BCG vaccine, live (PF)
- bedaquiline
- Beyaz
- bortezomib
- Bosulif
- bosutinib
- Brevicon (28)
- Briellyn
- Brilinta
- cabozantinib
- Camila
- Camptosar
- Camrese
- Camrese Lo
- Caprelsa
- Caziant (28)
- Cenestin
- Chateal
- Climara
- Climara Pro
- Combipatch
- Cometriq
- conj estrogens-bazedoxifene
- conjugated estrogens
- Coumadin
- Covaryx
- Covaryx H.s.
- Crixivan
- crizotinib
- Cryselle (28)
- Cyclafem 1/35 (28)
- Cyclafem 7/7/7 (28)
- Cyclessa (28)
- cyclosporine
- cyclosporine modified
- dabrafenib
- darunavir
- dasatinib
- Dasetta 1/35 (28)
- Dasetta 7/7/7 (28)
- Daysee
- Delestrogen
- Depo-estradiol
- Depo-provera
- Depo-subq Provera 104
- desog-e.estradiol/e.estradiol
- Desogen
- desogestrel-ethinyl estradiol
- dextromethorphan-quinidine
- Divigel
- drospirenone-e.estradiol-lm.FA
- drospirenone-estradiol
- drospirenone-ethinyl estradiol
- Duavee
- Eemt
- Eemt Hs
- Elestrin
- Elinest
- Elixophyllin
- elvitegr-cobicist-emtric-tenof
- Emend
- Emoquette
- Enjuvia
- Enpresse
- Enskyce
- enzalutamide
- erlotinib
- Errin
- Estarylla
- esterified estrogens
- Estrace
- estradiol
- estradiol acetate
- estradiol cypionate
- Estradiol Transdermal Patch
- estradiol valerate
- estradiol valerate-dienogest
- estradiol-levonorgestrel
- estradiol-norethindrone acet
- estradiol-norgestimate
- Estrasorb
- Estring
- Estrogel
- estrogens-methyltestosterone
- estropipate
- Estrostep Fe-28
- ethynodiol diac-eth estradiol
- etonogestrel
- etonogestrel-ethinyl estradiol
- etravirine
- Evamist
- everolimus
- Falmina (28)
- Fareston
- Femcon Fe
- Femhrt Low Dose
- Femring
- fosamprenavir
- fosaprepitant
- Generess Fe
- Gengraf
- Gianvi (28)
- Gildagia
- Gildess
- Gildess Fe
- Gleevec
- guanfacine
- Heather
- Hecoria
- ibrutinib
- imatinib
- Imbruvica
- Incivek
- indinavir
- Inlyta
- Intelence
- Introvale
- Intuniv Er
- Invirase
- irinotecan
- Istodax
- ixabepilone
- Ixempra
- Jantoven
- Jencycla
- Jinteli
- Jolessa
- Jolivette
- Junel 1.5/30 (21)
- Junel 1/20 (21)
- Junel Fe 1.5/30 (28)
- Junel Fe 1/20 (28)
- Kaletra
- Kariva (28)
- Kelnor 1/35 (28)
- Ketek
- Kurvelo
- L norgest&E estradiol-E estrad
- lapatinib
- Larin 1/20 (21)
- Larin Fe
- Leena 28
- Lessina
- Levonest (28)
- levonorg-eth estrad triphasic
- levonorgestrel
- levonorgestrel-ethinyl estrad
- Levora 0.15/30 (28)
- Levora-28
- Lexiva
- Lo Loestrin Fe
- Loestrin 1.5/30 (21)
- Loestrin 1/20 (21)
- Loestrin Fe 1.5/30 (28)
- Loestrin Fe 1/20 (28)
- Lomedia 24 Fe
- lopinavir-ritonavir
- Loryna (28)
- Loseasonique
- Low-ogestrel (28)
- Lutera (28)
- Lyza
- Marlissa
- medroxyprogesterone
- mefloquine
- Menest
- Menostar
- Microgestin 1.5/30 (21)
- Microgestin 1/20 (21)
- Microgestin Fe 1.5/30 (28)
- Microgestin Fe 1/20 (28)
- Mimvey
- Minastrin 24 Fe
- Minivelle
- Mircette (28)
- Mirena
- Modicon (28)
- Mono-linyah
- Mononessa (28)
- My Way
- Myzilra
- Natazia
- Necon 0.5/35 (28)
- Necon 1/35 (28)
- Necon 1/50 (28)
- Necon 10/11 (28)
- Necon 7/7/7 (28)
- nelfinavir
- Neoral
- Nexavar
- Nexplanon
- Next Choice One Dose
- nilotinib
- Nor-qd
- Nora-be
- norelgestrom-ethinyl estradiol
- noreth-ethinyl estradiol-iron
- norethin-e.estradiol triphasic
- norethin-eth estrad biphasic
- norethindrone (contraceptive)
- norethindrone ac-eth estradiol
- norethindrone-e.estradiol-iron
- norethindrone-ethin estradiol
- norethindrone-mestranol
- norgestimate-ethinyl estradiol
- norgestrel-ethinyl estradiol
- Norinyl 1+35 (28)
- Norinyl 1+50 (28)
- Nortrel 0.5/35 (28)
- Nortrel 1/35 (21)
- Nortrel 1/35 (28)
- Nortrel 7/7/7 (28)
- Noxafil
- Nuedexta
- Nuvaring
- Ocella
- Ogen 2.5
- Ogestrel (28)
- Olysio
- Orsythia
- Ortho Evra
- Ortho Micronor
- Ortho Tri-cyclen (28)
- Ortho Tri-cyclen Lo (28)
- Ortho-cept (28)
- Ortho-cyclen (28)
- Ortho-novum 1/35 (28)
- Ortho-novum 7/7/7 (28)
- Ovcon-35 (28)
- pazopanib
- Philith
- Pimtrea (28)
- Pirmella
- Plan B One-step
- pomalidomide
- Pomalyst
- Portia
- posaconazole
- Prefest
- Premarin
- Previfem
- Prezista
- Prograf
- Qualaquin
- Quartette
- Quasense
- quetiapine
- quinidine gluconate
- quinidine sulfate
- quinine sulfate
- Rapamune
- Reclipsen (28)
- Reyataz
- romidepsin
- Safyral
- Samsca
- Sandimmune
- saquinavir mesylate
- Seasonique
- Seroquel Xr
- simeprevir
- sirolimus
- Sirturo
- Skyla
- Soltamox
- sorafenib
- Sprintec (28)
- Sprycel
- Sronyx
- Stribild
- sunitinib
- Sutent
- Syeda
- synthetic conj estrogens A
- synthetic conj estrogens B
- tacrolimus
- Tafinlar
- tamoxifen
- Tarceva
- Tasigna
- telaprevir
- telithromycin
- temsirolimus
- Tenex
- Theo-24
- Theochron
- theophylline
- theophylline in dextrose 5 %
- ticagrelor
- Tice Bcg
- Tilia Fe
- tolvaptan
- toremifene
- Torisel
- Tri-estarylla
- Tri-legest Fe
- Tri-linyah
- Tri-norinyl (28)
- Tri-previfem (28)
- Tri-sprintec (28)
- Trinessa (28)
- Trivora (28)
- Tykerb
- Vagifem
- vandetanib
- Velcade
- Velivet Triphasic Regimen (28)
- Vestura (28)
- Viorele (28)
- Viracept
- Vivelle-dot
- Votrient
- Vyfemla (28)
- warfarin
- Wera (28)
- Wymzya Fe
- Xalkori
- Xtandi
- Yasmin (28)
- Yaz 28
- Zarah
- Zenchent (28)
- Zenchent Fe
- Zeosa
- Zortress
- Zovia 1/35E (28)
- Zovia 1/50E (28)
Severe
Moderate
- 1-day
- 3 Day Vaginal
- 3-day Vaginal
- A-hydrocort
- A-methapred
- Abilify
- Abilify Discmelt
- Abilify Maintena
- afatinib
- alprazolam
- Alprazolam Intensol
- Amaryl
- Anucort-hc
- Anusol-hc
- aripiprazole
- Aristospan Intra-articular
- Aristospan Intralesional
- Aromasin
- Ativan
- atovaquone
- atovaquone-proguanil
- Atripla
- betamethasone acet & sod phos
- bosentan
- budesonide
- butoconazole nitrate
- Bystolic
- Calan
- Calan Sr
- Cardizem
- Cardizem Cd
- Cardizem La
- Cartia Xt
- carvedilol
- carvedilol phosphate
- Celestone Soluspan
- clotrimazole
- Clotrimazole 3 Day
- Clotrimazole-3
- Clotrimazole-7
- Colocort
- Coreg
- Coreg Cr
- Cortef
- Cortenema
- Cortifoam
- cortisone
- Depo-medrol
- dexamethasone
- Dexamethasone Intensol
- dexamethasone sodium phos (PF)
- dexamethasone sodium phosphate
- Dexpak 10 Day
- Dexpak 13 Day
- Dexpak 6 Day
- Diabeta
- Diastat
- Diastat Acudial
- diazepam
- Diazepam Intensol
- Diflucan
- Digox
- digoxin
- Dilacor Xr
- Dilt-xr
- diltiazem HCl
- Duetact
- Dutoprol
- efavirenz
- efavirenz-emtricitabin-tenofov
- Entocort Ec
- Erythrocin
- erythromycin
- erythromycin-sulfisoxazole
- exemestane
- Ez Use Joint-tunnel-trigger
- First-duke's
- First-mary's Mouthwash
- Flo-pred
- fluconazole
- fluconazole in dextrose(iso-o)
- fluconazole in NaCl (iso-osm)
- fludrocortisone
- Gilotrif
- glimepiride
- Glucovance
- glyburide
- glyburide micronized
- glyburide-metformin
- Glynase
- Grx Hicort 25
- Gynazole-1
- Gyne-lotrimin
- Gyne-lotrimin 7
- Haldol
- Haldol Decanoate
- haloperidol
- haloperidol decanoate
- haloperidol lactate
- Hemril-30
- hydrocortisone
- hydrocortisone acetate
- hydrocortisone sod succ (PF)
- hydrocortisone sod succinate
- Iclusig
- Inderal La
- Inderal Xl
- Innopran Xl
- isradipine
- itraconazole
- Kenalog
- ketoconazole
- Lanoxin
- Lanoxin Pediatric
- Lopressor Hct
- lorazepam
- Lorazepam Intensol
- macitentan
- Malarone
- Malarone Pediatric
- Matzim La
- Medrol
- Medrol (pak)
- Mepron
- methylprednisolone
- methylprednisolone acetate
- methylprednisolone sod suc(PF)
- methylprednisolone sodium succ
- methylprednisolone-bupivacaine
- metoprolol su-hydrochlorothiaz
- metoprolol succinate
- metoprolol ta-hydrochlorothiaz
- metoprolol tartrate
- mexiletine
- miconazole
- Miconazole 7
- miconazole nitrate
- Miconazole-3
- Miconazole-3 Prefil,cream,wipe
- miconazole-skin clnsr17
- midazolam
- midazolam (PF)
- Millipred
- Millipred Dp
- Monistat 1 Combo Pack
- Monistat 3
- Monistat 7
- Monistat 7 Cream, Appl, Wipes
- nebivolol
- Niravam
- nisoldipine
- nystatin-hydrocortisone-diphen
- nystatin-TCN-HC-diphenhydramin
- Onmel
- Opsumit
- Orapred
- Orapred Odt
- Oravig
- Pediapred
- Physicians Ez Use M-pred
- pioglitazone-glimepiride
- ponatinib
- prednisolone
- prednisolone acetate
- prednisolone sodium phosphate
- prednisone
- Prednisone Intensol
- Proctocort
- propafenone
- propranolol
- propranolol-hydrochlorothiazid
- Rayos
- Rectacort-hc
- regorafenib
- Risperdal
- Risperdal Consta
- Risperdal M-tab
- risperidone
- risperidone microspheres
- Rythmol
- Seroquel
- Solu-cortef
- Solu-cortef (pf)
- Solu-medrol
- Solu-medrol (pf)
- Sporanox
- Sporanox Pulsepak
- Stivarga
- Sular
- Sustiva
- Tarka
- Taztia Xt
- Terazol 3
- Terazol 7
- terconazole
- Tiazac
- tioconazole
- Tioconazole-1
- tolbutamide
- Toprol Xl
- Tracleer
- trandolapril-verapamil
- triamcinolone acetonide
- triamcinolone hexacetonide
- triamcinolone-lidocaine
- triazolam
- Uceris
- Vagistat-1
- Vagistat-3
- Valium
- verapamil
- Verelan
- Verelan Pm
- Veripred 20
- Xanax
- Xanax Xr
- None
Contraindicated
- Clostridium difficile infection
- Severe renal impairment
Severe
Moderate
- Neutropenic disorder
- Thrombocytopenic disorder
MYCOBUTIN (RIFABUTIN)
- Prevention of mycobacterium avium complex disease
- Skin rash
- Discoloration of sweat
- Discolored feces
- Dyschromia
- Nausea
- Saliva discoloration
- Sputum discoloration
- Tear discoloration
- Urine discoloration
- Vomiting
More Frequent
Severe
Less Severe
- None
- Dyspnea
- Flatulence
- Insomnia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Agranulocytosis
- Anaphylaxis
- Angioedema
- Arthralgias
- Bronchospastic pulmonary disease
- Clostridium difficile infection
- Conjunctivitis
- Dysgeusia
- Hemolysis
- Hepatitis
- Hypersensitivity drug reaction
- Hypotension
- Jaundice
- Leukopenia
- Lymphopenia
- Myalgias
- Myositis
- Neutropenic disorder
- Pancytopenia
- Seizure disorder
- Thrombocytopenic disorder
- Urticaria
- Uveitis
Less Severe
- Acute abdominal pain
- Chest pain
- Diarrhea
- Dyspepsia
- Eructation
- Fever
- Flu-like symptoms
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Rifabutin
Corneal deposits noted in HIV positive pediatric patients receiving MAC prophylaxis. Limited safety data.
- 1 Day – 18 Years
- Corneal deposits noted in HIV positive pediatric patients receiving MAC prophylaxis. Limited safety data.
Rifabutin
- Severity Level:
B
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Rifabutin
Potential adverse reaction. cdc does not rec breastfeed if patient has hiv
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Potential adverse reaction. cdc does not rec breastfeed if patient has hiv |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
Formulary Reference Tool