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PROSTIN VR PEDIATRIC (ALPROSTADIL)
- Congenital defect requiring patency of ductus arteriosus
500 mcg/mL injection solution
- Dosage information is not available
- None
Contraindicated
- None
Severe
Moderate
- None
- Pregnancy
Contraindicated
- Apnea
- Pyloroduodenal obstruction
- Respiratory distress syndrome in the newborn
Severe
Moderate
- Hypotension
- Increased risk of bleeding
PROSTIN VR PEDIATRIC (ALPROSTADIL)
- Congenital defect requiring patency of ductus arteriosus
- Apnea
- Flushing
- Hypocalcemia
- Fever
More Frequent
Severe
Less Severe
- Bradycardia
- Diarrhea
- Hypotension
- Seizure disorder
- Sepsis
- Tachycardia
- None
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anemia
- Bradypnea
- Cardiac arrest
- Chronic heart failure
- Disseminated intravascular coagulation
- Edema
- Erythema
- Hematuria
- Hemorrhage
- Hypercapnia
- Hyperkalemia
- Hypoglycemic disorder
- Hypokalemia
- Hypothermia
- Infantile cortical hyperostosis
- Intracerebral hemorrhage
- Irritability
- Joint stiffness
- Lethargy
- Neck hyperextension
- Oliguria
- Paroxysmal supraventricular tachycardia
- Peritonitis
- Respiratory depression
- Respiratory distress syndrome in the newborn
- Second degree atrioventricular heart block
- Shock
- Spasm of the right ventricle infundibulum
- Tachypnea
- Thrombocytopenic disorder
- Ventricular fibrillation
- Vomiting
- Wheezing
Less Severe
- None
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Alprostadil (Inj)
Risk of apnea in birth weight <2 kg. Monitor arterial pressure and respiratory status.
- 1 Day – 364 Days
- Risk of apnea in birth weight <2 kg. Monitor arterial pressure and respiratory status.
Alprostadil (injection)
- Severity Level:
1
- Additional Notes: Not indicated in women
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Alprostadil (pedi Only Inj)
Insufficient data available, dosage form not indicated for use in adults
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available, dosage form not indicated for use in adults |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Congenital defect requiring patency of ductus arteriosus | |
| Q20.3 | Discordant ventriculoarterial connection |
| Q21.3 | Tetralogy of fallot |
| Q22.0 | Pulmonary valve atresia |
| Q22.1 | Congenital pulmonary valve stenosis |
| Q22.4 | Congenital tricuspid stenosis |
| Q22.9 | Congenital malformation of tricuspid valve, unspecified |
| Q25.1 | Coarctation of aorta |
| Q25.4 | Other congenital malformations of aorta |
| Q25.5 | Atresia of pulmonary artery |
| 0-9 | A-Z |
|---|---|
| Q20.3 | Discordant ventriculoarterial connection |
| Q21.3 | Tetralogy of fallot |
| Q22.0 | Pulmonary valve atresia |
| Q22.1 | Congenital pulmonary valve stenosis |
| Q22.4 | Congenital tricuspid stenosis |
| Q22.9 | Congenital malformation of tricuspid valve, unspecified |
| Q25.1 | Coarctation of aorta |
| Q25.4 | Other congenital malformations of aorta |
| Q25.5 | Atresia of pulmonary artery |
Formulary Reference Tool