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PAMIDRONATE DISODIUM (PAMIDRONATE DISODIUM)
- Humoral hypercalcemia of malignancy
- Osteolytic bone metastases of breast cancer
- Paget's disease of bone
- Prevention of skeletal related event in multiple myeloma
30 mg/10 mL (3 mg/mL) intravenous solution
- Dosage information is not available
60 mg/10 mL (6 mg/mL) intravenous solution
- Dosage information is not available
90 mg/10 mL (9 mg/mL) intravenous solution
- Dosage information is not available
30 mg/10 mL (3 mg/mL) intravenous solution
- Dosage information is not available
60 mg/10 mL (6 mg/mL) intravenous solution
- Dosage information is not available
90 mg/10 mL (9 mg/mL) intravenous solution
- Dosage information is not available
pamidronate 30 mg/10 mL (3 mg/mL) intravenous solution
- Dosage information is not available
pamidronate 60 mg/10 mL (6 mg/mL) intravenous solution
- Dosage information is not available
pamidronate 90 mg/10 mL (9 mg/mL) intravenous solution
- Dosage information is not available
Humoral hypercalcemia of malignancy
- Infuse 90 mg over 2-24 hour(s) by intravenous route once ;May repeat in 7 days or every 2-4 weeks
- Infuse 60 mg over 2-24 hour(s) by intravenous route once ;May repeat in 7 days or every 2-4 weeks
Osteolytic bone metastases of breast cancer
- Infuse 90 mg over 2 hour(s) by intravenous route every 3 weeks
- Infuse 90 mg over 2 hour(s) by intravenous route every 4 weeks
Paget's disease of bone
- Infuse 30 mg over 4 hour(s) by intravenous route once daily for 3 days
Prevention of skeletal related event in multiple myeloma
- Infuse 90 mg over 2 hour(s) by intravenous route every 3 weeks
- Infuse 90 mg over 2 hour(s) by intravenous route every 4 weeks
- None
Contraindicated
- None
Severe
Moderate
- None
- Aseptic necrosis of jaw bone
Contraindicated
- Dehydration
- Hypovolemia
- Invasive dental procedure
- Kidney disease with reduction in GFR
- Periodontitis
- Pregnancy
Severe
Moderate
- Hypocalcemia
- Hypokalemia
- Hypomagnesemia
- Hypophosphatemia
- Thyroid surgery
PAMIDRONATE DISODIUM (PAMIDRONATE DISODIUM)
- Humoral hypercalcemia of malignancy
- Osteolytic bone metastases of breast cancer
- Paget's disease of bone
- Prevention of skeletal related event in multiple myeloma
- Body fluid retention
- Hypertension
- Hypocalcemia
- Hypokalemia
- Hypomagnesemia
- Pleural effusions
- Abdominal pain with cramps
- Anemia
- Anorexia
- Arthralgias
- Candidiasis
- Constipation
- Cough
- Dyspnea
- Fatigue
- Fever
- General weakness
- Granulocytopenic disorder
- Headache disorder
- Hypophosphatemia
- Injection site sequelae
- Insomnia
- Nausea
- Osteoarthritis
- Pain
- Rales
- Rhinitis
- Sinusitis
- Symptoms of anxiety
- Upper respiratory infection
- Urinary tract infection
- Vomiting
More Frequent
Severe
Less Severe
- Drug-induced psychosis
- Edema
- Tachycardia
- Chills
- Diarrhea
- Drowsy
- Dyspepsia
- Muscle rigidity
- Stomatitis
- Uremia
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Acute respiratory distress syndrome
- Anaphylaxis
- Angioedema
- Aseptic necrosis of jaw bone
- Atrial flutter
- Atypical femoral fracture
- Bone pain
- Focal segmental glomerulosclerosis
- Gastrointestinal hemorrhage
- Heart failure
- Hypotension
- Inflammation of orbit
- Interstitial lung disease
- Interstitial nephritis
- Iritis
- Kidney disease with reduction in GFR
- Leukopenia
- Neutropenic disorder
- Scleritis
- Syncope
- Thrombocytopenic disorder
- Uveitis
Less Severe
- Acute confusion
- Conjunctivitis
- Flu-like symptoms
- Hallucinations
- Hematuria
- Hyperkalemia
- Hypernatremia
- Hypothyroidism
- Malaise
- Myalgias
- Pruritus of skin
- Renal failure
- Skin rash
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Pamidronate
Limited safety data available. Not approved in pediatrics.
- 1 Day – 18 Years
- Limited safety data available. Not approved in pediatrics.
Pamidronate
- Severity Level:
D
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Pamidronate
Insufficient data available.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient data available. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
None
No Known Risk
None
- None
| Humoral hypercalcemia of malignancy | |
| E83.52 | Hypercalcemia |
| Osteolytic bone metastases of breast cancer | |
| C79.51 | Secondary malignant neoplasm of bone |
| Paget's disease of bone | |
| M88 | Osteitis deformans [paget's disease of bone] |
| M88.0 | Osteitis deformans of skull |
| M88.1 | Osteitis deformans of vertebrae |
| M88.8 | Osteitis deformans of other bones |
| M88.81 | Osteitis deformans of shoulder |
| M88.811 | Osteitis deformans of right shoulder |
| M88.812 | Osteitis deformans of left shoulder |
| M88.819 | Osteitis deformans of unspecified shoulder |
| M88.82 | Osteitis deformans of upper arm |
| M88.821 | Osteitis deformans of right upper arm |
| M88.822 | Osteitis deformans of left upper arm |
| M88.829 | Osteitis deformans of unspecified upper arm |
| M88.83 | Osteitis deformans of forearm |
| M88.831 | Osteitis deformans of right forearm |
| M88.832 | Osteitis deformans of left forearm |
| M88.839 | Osteitis deformans of unspecified forearm |
| M88.84 | Osteitis deformans of hand |
| M88.841 | Osteitis deformans of right hand |
| M88.842 | Osteitis deformans of left hand |
| M88.849 | Osteitis deformans of unspecified hand |
| M88.85 | Osteitis deformans of thigh |
| M88.851 | Osteitis deformans of right thigh |
| M88.852 | Osteitis deformans of left thigh |
| M88.859 | Osteitis deformans of unspecified thigh |
| M88.86 | Osteitis deformans of lower leg |
| M88.861 | Osteitis deformans of right lower leg |
| M88.862 | Osteitis deformans of left lower leg |
| M88.869 | Osteitis deformans of unspecified lower leg |
| M88.87 | Osteitis deformans of ankle and foot |
| M88.871 | Osteitis deformans of right ankle and foot |
| M88.872 | Osteitis deformans of left ankle and foot |
| M88.879 | Osteitis deformans of unspecified ankle and foot |
| M88.88 | Osteitis deformans of other bones |
| M88.89 | Osteitis deformans of multiple sites |
| M88.9 | Osteitis deformans of unspecified bone |
| Prevention of skeletal related event in multiple myeloma | |
| C90.0 | Multiple myeloma |
| C90.00 | Multiple myeloma not having achieved remission |
| C90.02 | Multiple myeloma in relapse |
| 0-9 | A-Z |
|---|---|
| C79.51 | Secondary malignant neoplasm of bone |
| C90.0 | Multiple myeloma |
| C90.00 | Multiple myeloma not having achieved remission |
| C90.02 | Multiple myeloma in relapse |
| E83.52 | Hypercalcemia |
| M88 | Osteitis deformans [paget's disease of bone] |
| M88.0 | Osteitis deformans of skull |
| M88.1 | Osteitis deformans of vertebrae |
| M88.8 | Osteitis deformans of other bones |
| M88.81 | Osteitis deformans of shoulder |
| M88.811 | Osteitis deformans of right shoulder |
| M88.812 | Osteitis deformans of left shoulder |
| M88.819 | Osteitis deformans of unspecified shoulder |
| M88.82 | Osteitis deformans of upper arm |
| M88.821 | Osteitis deformans of right upper arm |
| M88.822 | Osteitis deformans of left upper arm |
| M88.829 | Osteitis deformans of unspecified upper arm |
| M88.83 | Osteitis deformans of forearm |
| M88.831 | Osteitis deformans of right forearm |
| M88.832 | Osteitis deformans of left forearm |
| M88.839 | Osteitis deformans of unspecified forearm |
| M88.84 | Osteitis deformans of hand |
| M88.841 | Osteitis deformans of right hand |
| M88.842 | Osteitis deformans of left hand |
| M88.849 | Osteitis deformans of unspecified hand |
| M88.85 | Osteitis deformans of thigh |
| M88.851 | Osteitis deformans of right thigh |
| M88.852 | Osteitis deformans of left thigh |
| M88.859 | Osteitis deformans of unspecified thigh |
| M88.86 | Osteitis deformans of lower leg |
| M88.861 | Osteitis deformans of right lower leg |
| M88.862 | Osteitis deformans of left lower leg |
| M88.869 | Osteitis deformans of unspecified lower leg |
| M88.87 | Osteitis deformans of ankle and foot |
| M88.871 | Osteitis deformans of right ankle and foot |
| M88.872 | Osteitis deformans of left ankle and foot |
| M88.879 | Osteitis deformans of unspecified ankle and foot |
| M88.88 | Osteitis deformans of other bones |
| M88.89 | Osteitis deformans of multiple sites |
| M88.9 | Osteitis deformans of unspecified bone |
Formulary Reference Tool