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DIMETAPP COLD-CONGESTION (phenylephrine HCl/diphenhydramine HCl)
- cold symptoms
- inflammation of the nose due to an allergy
- stuffy nose
- allergic conjunctivitis
- non-seasonal allergic stuffy and runny nose
- runny nose
- seasonal runny nose
- sneezing
- vasomotor rhinitis
- Triaminic Cold And Cough Night Time (pe) Oral Liquid
- Kindermed Kids Night Cold-cough Oral Liquid
- Dimetapp Cold-congestion Oral Liquid
- Childs Triacting Cold And Cough Oral Liquid
- Childs Triacting Cold & Cough Oral Liquid
- Children Night Time Cold-cough Oral Liquid
Triaminic Cold and Cough Night Time(PE)6.25 mg-2.5 mg/5 mL oral liquid
- Dosage information is not available
KinderMed Kids Night Cold-Cough 6.25 mg-2.5 mg/5 mL oral liquid
- Dosage information is not available
6.25 mg-2.5 mg/5 mL oral liquid
- Dosage information is not available
Dimetapp Cold-Congestion 6.25 mg-2.5 mg/5 mL oral liquid
- Dosage information is not available
Childs Triacting Cold and Cough 6.25 mg-2.5 mg/5 mL oral liquid
- Dosage information is not available
Childs Triacting Cold and Cough 6.25 mg-2.5 mg/5 mL oral liquid
- Dosage information is not available
6.25 mg-2.5 mg/5 mL oral liquid
- Dosage information is not available
Children Night Time Cold-Cough 6.25 mg-2.5 mg/5 mL oral liquid
- Dosage information is not available
- isocarboxazid
- Marplan
- Matulane
- methylene blue (antidote)
- Nardil
- Parnate
- phenelzine
- procarbazine
- tranylcypromine
Contraindicated
- Azilect
- bromocriptine
- cabergoline
- Cafergot
- Compound 347
- Cycloset
- D.h.e.45
- dihydroergotamine
- Eldepryl
- enflurane
- ergoloid
- Ergomar
- ergotamine tartrate
- ergotamine-caffeine
- Forane
- isoflurane
- K-tab
- Klor-con
- Klor-con 10
- Klor-con M10
- Klor-con M15
- Klor-con M20
- linezolid
- Medi-lyte
- methylergonovine
- Migergot
- Migranal
- Parlodel
- potassium chloride
- potassium citrate
- potassium Cl-calcium phos-mag
- rasagiline
- selegiline HCl
- sevoflurane
- sodium Cl-potassium chloride
- Sojourn
- Terrell
- Thermotabs
- Ultane
- Urocit-k 10
- Urocit-k 15
- Urocit-k 5
- Zelapar
- Zyvox
Severe
Moderate
- methyldopa
- methyldopa-hydrochlorothiazide
- methyldopate
- reserpine
- Soltamox
- tamoxifen
- Severe uncontrolled hypertension
Contraindicated
- Angle-closure glaucoma
- Benign prostatic hyperplasia
- Bladder outflow obstruction
- Chronic idiopathic constipation
- Coronary artery disease
- Hypertension
- Hyperthyroidism
- Stenosing peptic ulcer
- Urinary retention
Severe
Moderate
- Chronic heart failure
- Hypertension
- Hyperthyroidism
- Ocular hypertension
DIMETAPP COLD-CONGESTION (phenylephrine HCl/diphenhydramine HCl)
- cold symptoms
- inflammation of the nose due to an allergy
- stuffy nose
- allergic conjunctivitis
- non-seasonal allergic stuffy and runny nose
- runny nose
- seasonal runny nose
- sneezing
- vasomotor rhinitis
- None
- Dizziness
- Drowsy
- Thick bronchial secretions
More Frequent
Severe
Less Severe
- None
- Sedation
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Anaphylaxis
- Blood dyscrasias
- Cardiac arrhythmia
- Dizziness
- Extrasystoles
- Hallucinations
- Headache disorder
- Hemolytic anemia
- Hyperhidrosis
- Hypersensitivity drug reaction
- Hypotension
- Insomnia
- Nervousness
- Pallor
- Seizure disorder
- Tachycardia
- Tremor
Less Severe
- Abdominal distension
- Acute abdominal pain
- Acute confusion
- Anorexia
- Ataxia
- Blurred vision
- Chest discomfort
- Chills
- Constipation
- Diarrhea
- Diplopia
- Dry nose
- Dry throat
- Dyspnea
- Dysuria
- Euphoria
- Excitement
- Fatigue
- Headache disorder
- Hyperhidrosis
- Increased urinary frequency
- Insomnia
- Irritability
- Maculopapular rash
- Malaise
- Migraine
- Nervousness
- Nightmares
- Palpitations
- Paresthesia
- Pruritus of skin
- Skin photosensitivity
- Skin rash
- Symptoms of anxiety
- Tachycardia
- Tinnitus
- Tremor
- Urinary retention
- Urticaria
- Vertigo
- Visual changes
- Vomiting
- Wheezing
- Xerostomia
Contraindicated
Diphenhydramine (Cough-Cold)
Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation; risk of respiratory depression.
Possible risk of CNS excitation, convulsions in newborns.
Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 30 Days – 6 Years
- 1 Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation; risk of respiratory depression.
- 1 Day – 29 Days
- 1 Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation; risk of respiratory depression.
- 1 Day – 6 Years
- 1 Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation; risk of respiratory depression.
Diphenhydramine (oral)
Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation; risk of respiratory depression.
Possible risk of CNS excitation, convulsions in newborns.
Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 30 Days – 6 Years
- 1 Possible risk of CNS excitation, convulsions in newborns.
- 1 Day – 29 Days
- 1 Possible risk of CNS excitation, convulsions in newborns.
- 1 Day – 6 Years
- 1 Possible risk of CNS excitation, convulsions in newborns.
Phenylephrine (oral)
Do not use unless as directed by clinician consultation. Risk of adverse CNS effects include sedation or paradoxical excitation; risk of respiratory depression.
Possible risk of CNS excitation, convulsions in newborns.
Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 30 Days – 6 Years
- 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 1 Day – 29 Days
- 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
- 1 Day – 6 Years
- 1 Risk of CNS excitation. Do not use age <6 years without clinician consult.
Severe Precaution
None
Management or Monitoring Precaution
None
Diphenhydramine
- Severity Level:
B
- Additional Notes:
Phenylephrine
- Severity Level:
2
- Additional Notes: Insufficient human data available.
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Diphenhydramine
Limited data suggest increased drowsiness, and irritability
Oral bioavailability low; infant exposure may be minimal
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Limited data suggest increased drowsiness, and irritability |
Phenylephrine
Limited data suggest increased drowsiness, and irritability
Oral bioavailability low; infant exposure may be minimal
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Excreted | Not known; no or inclusive data | Oral bioavailability low; infant exposure may be minimal |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Diphenhydramine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Maximum of 25mg/day. Cardiovascular-May cause orthostatic hypotension at higher doses. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | N | Y | N | N |
BEERS: Y HEDIS: Y STOPP: Y
Phenylephrine
Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Maximum of 25mg/day. Cardiovascular-May cause orthostatic hypotension at higher doses. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | Y | Y | N | N |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Allergic conjunctivitis | |
| H10.1 | Acute atopic conjunctivitis |
| H10.10 | Acute atopic conjunctivitis, unspecified eye |
| H10.11 | Acute atopic conjunctivitis, right eye |
| H10.12 | Acute atopic conjunctivitis, left eye |
| H10.13 | Acute atopic conjunctivitis, bilateral |
| H10.44 | Vernal conjunctivitis |
| H10.45 | Other chronic allergic conjunctivitis |
| H16.26 | Vernal keratoconjunctivitis, with limbar and corneal involvement |
| H16.261 | Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye |
| H16.262 | Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye |
| H16.263 | Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral |
| H16.269 | Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye |
| Allergic rhinitis | |
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| J30.5 | Allergic rhinitis due to food |
| J30.8 | Other allergic rhinitis |
| J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
| J30.89 | Other allergic rhinitis |
| J30.9 | Allergic rhinitis, unspecified |
| Cold symptoms | |
| J00 | Acute nasopharyngitis [common cold] |
| Nasal congestion | |
| R09.81 | Nasal congestion |
| Perennial allergic rhinitis | |
| J31.0 | Chronic rhinitis |
| Rhinorrhea | |
| R09.82 | Postnasal drip |
| Seasonal allergic rhinitis | |
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| Sneezing | |
| R06.7 | Sneezing |
| Vasomotor rhinitis | |
| J30.0 | Vasomotor rhinitis |
| 0-9 | A-Z |
|---|---|
| H10.1 | Acute atopic conjunctivitis |
| H10.10 | Acute atopic conjunctivitis, unspecified eye |
| H10.11 | Acute atopic conjunctivitis, right eye |
| H10.12 | Acute atopic conjunctivitis, left eye |
| H10.13 | Acute atopic conjunctivitis, bilateral |
| H10.44 | Vernal conjunctivitis |
| H10.45 | Other chronic allergic conjunctivitis |
| H16.26 | Vernal keratoconjunctivitis, with limbar and corneal involvement |
| H16.261 | Vernal keratoconjunctivitis, with limbar and corneal involvement, right eye |
| H16.262 | Vernal keratoconjunctivitis, with limbar and corneal involvement, left eye |
| H16.263 | Vernal keratoconjunctivitis, with limbar and corneal involvement, bilateral |
| H16.269 | Vernal keratoconjunctivitis, with limbar and corneal involvement, unspecified eye |
| J00 | Acute nasopharyngitis [common cold] |
| J30.0 | Vasomotor rhinitis |
| J30.1 | Allergic rhinitis due to pollen |
| J30.1 | Allergic rhinitis due to pollen |
| J30.2 | Other seasonal allergic rhinitis |
| J30.2 | Other seasonal allergic rhinitis |
| J30.5 | Allergic rhinitis due to food |
| J30.8 | Other allergic rhinitis |
| J30.81 | Allergic rhinitis due to animal (cat) (dog) hair and dander |
| J30.89 | Other allergic rhinitis |
| J30.9 | Allergic rhinitis, unspecified |
| J31.0 | Chronic rhinitis |
| R06.7 | Sneezing |
| R09.81 | Nasal congestion |
| R09.82 | Postnasal drip |
Formulary Reference Tool