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NEO-POLYCIN HC (neomycin sulfate/bacitracin zinc/polymyxin B/hydrocortisone)
- bacterial infection of the eyelid
- inflammation of eyelid edges and the lining of the eye
- inflammation of the cornea of the eye
- inflammation of the cornea of the eye due to bacteria
- scratch wound on cornea
3.5 mg-400-10,000 unit/g-1 % eye ointment
- Apply a small amount into the conjunctival sac(s) in affected eye(s) by ophthalmic route every 4 hours
3.5 mg-400-10,000 unit/g-1 % eye ointment
- Apply a small amount into the conjunctival sac(s) in affected eye(s) by ophthalmic route every 4 hours
Bacterial blepharitis
- Apply a small amount in the conjunctival sacs in both eyes by ophthalmic route every 3 hours
- Apply a small amount in the conjunctival sac in the left eye by ophthalmic route every 4 hours
- Apply a small amount into the conjunctival sac in the right eye by ophthalmic route every 4 hours
- Apply a small amount in the conjunctival sac in the left eye by ophthalmic route every 3 hours
- Apply a small amount into the conjunctival sac in the right eye by ophthalmic route every 3 hours
- Apply a small amount in the conjunctival sacs in both eyes by ophthalmic route every 4 hours
- Apply a small amount into the conjunctival sac(s) in affected eye(s) by ophthalmic route every 3 hours
- Apply a small amount into the conjunctival sac(s) in affected eye(s) by ophthalmic route every 4 hours
- None
Contraindicated
- None
Severe
Moderate
- None
- Fungal infection of eye
- Herpes simplex dendritic keratitis
- Tuberculosis of the eye
- Vaccinia virus keratitis
Contraindicated
- Amebic infection of the eye
- Ocular hypertension
- Ocular injury
Severe
Moderate
- Diabetes mellitus
- Krukenberg spindle
- No disease contraindications
- Open angle glaucoma
- Severe myopia
NEO-POLYCIN HC (neomycin sulfate/bacitracin zinc/polymyxin B/hydrocortisone)
- bacterial infection of the eyelid
- inflammation of eyelid edges and the lining of the eye
- inflammation of the cornea of the eye
- inflammation of the cornea of the eye due to bacteria
- scratch wound on cornea
- Contact dermatitis
- Ocular inflammation
- Ocular itching
- Ocular redness
- Skin rash
- Blurred vision
More Frequent
Severe
Less Severe
- Ocular hypertension
- Ocular irritation
- Blurred vision
- Headache disorder
- Iritis
- Ocular irritation
- Ocular pain
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Adrenocortical insufficiency
- Anaphylaxis
- Bullous dermatitis
- Cataracts
- Central serous chorioretinopathy
- Corneal degeneration
- Corneal edema
- Corneal erosion
- Corneal ulcer
- Fungal infection of eye
- Glaucoma
- Globe perforation
- Hypercortisolism
- Hypersensitivity drug reaction
- Keratitis
- Optic nerve damage
- Punctate keratitis
- Reduced visual acuity
- Uveitis
- Visual changes
- Visual field defect
Less Severe
- Accommodation disorder
- Allergic dermatitis
- Blepharoptosis
- Chemosis
- Conjunctival hyperemia
- Conjunctivitis
- Dizziness
- Dysgeusia
- Eye tearing
- Foreign body sensation of eye
- Impaired wound healing
- Mydriasis
- Ocular infection
- Ocular irritation
- Ocular itching
- Ocular redness
- Photophobia
- Urticaria
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Hydrocortisone (Top,Ophth,Rect)
Prolonged or extensive use may lead to systemic absorption; may affect growth rate.
- 1 Day – 18 Years
- Prolonged or extensive use may lead to systemic absorption; may affect growth rate.
Bacitracin (ophth,top)
- Severity Level:
2
- Additional Notes: Insufficient data available
Hydrocortisone (topical, Non-systemic)
- Severity Level:
2
- Additional Notes: Insufficient human data available
Neomycin (ophth)
- Severity Level:
C
- Additional Notes: No single ingredient data. fda category c in combination product.
Polymyxin B Sulfate (ophth,otic,top)
- Severity Level:
B
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Bacitracin (inj,top,ophth)
Insufficient human data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available |
Neomycin (topical, Ophth)
Insufficient human data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available |
Polymyxin B
Insufficient human data available
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Insufficient human data available |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Hydrocortisone (ophth)
Increased risk of diabetes, cataracts, or glaucoma. Frequent ophthalmic exams recommended.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | N | N | N | N | N | Y |
BEERS: N HEDIS: N STOPP: N
No Known Risk
None
- None
| Bacterial blepharitis | |
| H01.0 | Blepharitis |
| H01.00 | Unspecified blepharitis |
| H01.001 | Unspecified blepharitis right upper eyelid |
| H01.002 | Unspecified blepharitis right lower eyelid |
| H01.003 | Unspecified blepharitis right eye, unspecified eyelid |
| H01.004 | Unspecified blepharitis left upper eyelid |
| H01.005 | Unspecified blepharitis left lower eyelid |
| H01.006 | Unspecified blepharitis left eye, unspecified eyelid |
| H01.009 | Unspecified blepharitis unspecified eye, unspecified eyelid |
| H01.00A | Unspecified blepharitis right eye, upper and lower eyelids |
| H01.00B | Unspecified blepharitis left eye, upper and lower eyelids |
| H01.01 | Ulcerative blepharitis |
| H01.011 | Ulcerative blepharitis right upper eyelid |
| H01.012 | Ulcerative blepharitis right lower eyelid |
| H01.013 | Ulcerative blepharitis right eye, unspecified eyelid |
| H01.014 | Ulcerative blepharitis left upper eyelid |
| H01.015 | Ulcerative blepharitis left lower eyelid |
| H01.016 | Ulcerative blepharitis left eye, unspecified eyelid |
| H01.019 | Ulcerative blepharitis unspecified eye, unspecified eyelid |
| H01.01A | Ulcerative blepharitis right eye, upper and lower eyelids |
| H01.01B | Ulcerative blepharitis left eye, upper and lower eyelids |
| H01.02 | Squamous blepharitis |
| H01.021 | Squamous blepharitis right upper eyelid |
| H01.022 | Squamous blepharitis right lower eyelid |
| H01.023 | Squamous blepharitis right eye, unspecified eyelid |
| H01.024 | Squamous blepharitis left upper eyelid |
| H01.025 | Squamous blepharitis left lower eyelid |
| H01.026 | Squamous blepharitis left eye, unspecified eyelid |
| H01.029 | Squamous blepharitis unspecified eye, unspecified eyelid |
| H01.02A | Squamous blepharitis right eye, upper and lower eyelids |
| H01.02B | Squamous blepharitis left eye, upper and lower eyelids |
| Bacterial keratitis | |
| H16.10 | Unspecified superficial keratitis |
| H16.101 | Unspecified superficial keratitis, right eye |
| H16.102 | Unspecified superficial keratitis, left eye |
| H16.103 | Unspecified superficial keratitis, bilateral |
| H16.109 | Unspecified superficial keratitis, unspecified eye |
| H16.32 | Diffuse interstitial keratitis |
| H16.321 | Diffuse interstitial keratitis, right eye |
| H16.322 | Diffuse interstitial keratitis, left eye |
| H16.323 | Diffuse interstitial keratitis, bilateral |
| H16.329 | Diffuse interstitial keratitis, unspecified eye |
| H16.39 | Other interstitial and deep keratitis |
| H16.391 | Other interstitial and deep keratitis, right eye |
| H16.392 | Other interstitial and deep keratitis, left eye |
| H16.393 | Other interstitial and deep keratitis, bilateral |
| H16.399 | Other interstitial and deep keratitis, unspecified eye |
| H16.8 | Other keratitis |
| Blepharoconjunctivitis | |
| H10.5 | Blepharoconjunctivitis |
| H10.50 | Unspecified blepharoconjunctivitis |
| H10.501 | Unspecified blepharoconjunctivitis, right eye |
| H10.502 | Unspecified blepharoconjunctivitis, left eye |
| H10.503 | Unspecified blepharoconjunctivitis, bilateral |
| H10.509 | Unspecified blepharoconjunctivitis, unspecified eye |
| H10.52 | Angular blepharoconjunctivitis |
| H10.521 | Angular blepharoconjunctivitis, right eye |
| H10.522 | Angular blepharoconjunctivitis, left eye |
| H10.523 | Angular blepharoconjunctivitis, bilateral |
| H10.529 | Angular blepharoconjunctivitis, unspecified eye |
| Corneal abrasion | |
| S05.00xA | Injury of conjunctiva and corneal abrasion without foreign body, unspecified eye, initial encounter |
| S05.01xA | Injury of conjunctiva and corneal abrasion without foreign body, right eye, initial encounter |
| S05.02xA | Injury of conjunctiva and corneal abrasion without foreign body, left eye, initial encounter |
| Keratitis | |
| H16 | Keratitis |
| H16.10 | Unspecified superficial keratitis |
| H16.101 | Unspecified superficial keratitis, right eye |
| H16.102 | Unspecified superficial keratitis, left eye |
| H16.103 | Unspecified superficial keratitis, bilateral |
| H16.109 | Unspecified superficial keratitis, unspecified eye |
| H16.11 | Macular keratitis |
| H16.111 | Macular keratitis, right eye |
| H16.112 | Macular keratitis, left eye |
| H16.113 | Macular keratitis, bilateral |
| H16.119 | Macular keratitis, unspecified eye |
| H16.12 | Filamentary keratitis |
| H16.121 | Filamentary keratitis, right eye |
| H16.122 | Filamentary keratitis, left eye |
| H16.123 | Filamentary keratitis, bilateral |
| H16.129 | Filamentary keratitis, unspecified eye |
| H16.13 | Photokeratitis |
| H16.131 | Photokeratitis, right eye |
| H16.132 | Photokeratitis, left eye |
| H16.133 | Photokeratitis, bilateral |
| H16.139 | Photokeratitis, unspecified eye |
| H16.14 | Punctate keratitis |
| H16.141 | Punctate keratitis, right eye |
| H16.142 | Punctate keratitis, left eye |
| H16.143 | Punctate keratitis, bilateral |
| H16.149 | Punctate keratitis, unspecified eye |
| H16.30 | Unspecified interstitial keratitis |
| H16.301 | Unspecified interstitial keratitis, right eye |
| H16.302 | Unspecified interstitial keratitis, left eye |
| H16.303 | Unspecified interstitial keratitis, bilateral |
| H16.309 | Unspecified interstitial keratitis, unspecified eye |
| H16.32 | Diffuse interstitial keratitis |
| H16.321 | Diffuse interstitial keratitis, right eye |
| H16.322 | Diffuse interstitial keratitis, left eye |
| H16.323 | Diffuse interstitial keratitis, bilateral |
| H16.329 | Diffuse interstitial keratitis, unspecified eye |
| H16.33 | Sclerosing keratitis |
| H16.331 | Sclerosing keratitis, right eye |
| H16.332 | Sclerosing keratitis, left eye |
| H16.333 | Sclerosing keratitis, bilateral |
| H16.339 | Sclerosing keratitis, unspecified eye |
| H16.39 | Other interstitial and deep keratitis |
| H16.391 | Other interstitial and deep keratitis, right eye |
| H16.392 | Other interstitial and deep keratitis, left eye |
| H16.393 | Other interstitial and deep keratitis, bilateral |
| H16.399 | Other interstitial and deep keratitis, unspecified eye |
| H16.8 | Other keratitis |
| H16.9 | Unspecified keratitis |
| 0-9 | A-Z |
|---|---|
| H01.0 | Blepharitis |
| H01.00 | Unspecified blepharitis |
| H01.001 | Unspecified blepharitis right upper eyelid |
| H01.002 | Unspecified blepharitis right lower eyelid |
| H01.003 | Unspecified blepharitis right eye, unspecified eyelid |
| H01.004 | Unspecified blepharitis left upper eyelid |
| H01.005 | Unspecified blepharitis left lower eyelid |
| H01.006 | Unspecified blepharitis left eye, unspecified eyelid |
| H01.009 | Unspecified blepharitis unspecified eye, unspecified eyelid |
| H01.00A | Unspecified blepharitis right eye, upper and lower eyelids |
| H01.00B | Unspecified blepharitis left eye, upper and lower eyelids |
| H01.01 | Ulcerative blepharitis |
| H01.011 | Ulcerative blepharitis right upper eyelid |
| H01.012 | Ulcerative blepharitis right lower eyelid |
| H01.013 | Ulcerative blepharitis right eye, unspecified eyelid |
| H01.014 | Ulcerative blepharitis left upper eyelid |
| H01.015 | Ulcerative blepharitis left lower eyelid |
| H01.016 | Ulcerative blepharitis left eye, unspecified eyelid |
| H01.019 | Ulcerative blepharitis unspecified eye, unspecified eyelid |
| H01.01A | Ulcerative blepharitis right eye, upper and lower eyelids |
| H01.01B | Ulcerative blepharitis left eye, upper and lower eyelids |
| H01.02 | Squamous blepharitis |
| H01.021 | Squamous blepharitis right upper eyelid |
| H01.022 | Squamous blepharitis right lower eyelid |
| H01.023 | Squamous blepharitis right eye, unspecified eyelid |
| H01.024 | Squamous blepharitis left upper eyelid |
| H01.025 | Squamous blepharitis left lower eyelid |
| H01.026 | Squamous blepharitis left eye, unspecified eyelid |
| H01.029 | Squamous blepharitis unspecified eye, unspecified eyelid |
| H01.02A | Squamous blepharitis right eye, upper and lower eyelids |
| H01.02B | Squamous blepharitis left eye, upper and lower eyelids |
| H10.5 | Blepharoconjunctivitis |
| H10.50 | Unspecified blepharoconjunctivitis |
| H10.501 | Unspecified blepharoconjunctivitis, right eye |
| H10.502 | Unspecified blepharoconjunctivitis, left eye |
| H10.503 | Unspecified blepharoconjunctivitis, bilateral |
| H10.509 | Unspecified blepharoconjunctivitis, unspecified eye |
| H10.52 | Angular blepharoconjunctivitis |
| H10.521 | Angular blepharoconjunctivitis, right eye |
| H10.522 | Angular blepharoconjunctivitis, left eye |
| H10.523 | Angular blepharoconjunctivitis, bilateral |
| H10.529 | Angular blepharoconjunctivitis, unspecified eye |
| H16 | Keratitis |
| H16.10 | Unspecified superficial keratitis |
| H16.10 | Unspecified superficial keratitis |
| H16.101 | Unspecified superficial keratitis, right eye |
| H16.101 | Unspecified superficial keratitis, right eye |
| H16.102 | Unspecified superficial keratitis, left eye |
| H16.102 | Unspecified superficial keratitis, left eye |
| H16.103 | Unspecified superficial keratitis, bilateral |
| H16.103 | Unspecified superficial keratitis, bilateral |
| H16.109 | Unspecified superficial keratitis, unspecified eye |
| H16.109 | Unspecified superficial keratitis, unspecified eye |
| H16.11 | Macular keratitis |
| H16.111 | Macular keratitis, right eye |
| H16.112 | Macular keratitis, left eye |
| H16.113 | Macular keratitis, bilateral |
| H16.119 | Macular keratitis, unspecified eye |
| H16.12 | Filamentary keratitis |
| H16.121 | Filamentary keratitis, right eye |
| H16.122 | Filamentary keratitis, left eye |
| H16.123 | Filamentary keratitis, bilateral |
| H16.129 | Filamentary keratitis, unspecified eye |
| H16.13 | Photokeratitis |
| H16.131 | Photokeratitis, right eye |
| H16.132 | Photokeratitis, left eye |
| H16.133 | Photokeratitis, bilateral |
| H16.139 | Photokeratitis, unspecified eye |
| H16.14 | Punctate keratitis |
| H16.141 | Punctate keratitis, right eye |
| H16.142 | Punctate keratitis, left eye |
| H16.143 | Punctate keratitis, bilateral |
| H16.149 | Punctate keratitis, unspecified eye |
| H16.30 | Unspecified interstitial keratitis |
| H16.301 | Unspecified interstitial keratitis, right eye |
| H16.302 | Unspecified interstitial keratitis, left eye |
| H16.303 | Unspecified interstitial keratitis, bilateral |
| H16.309 | Unspecified interstitial keratitis, unspecified eye |
| H16.32 | Diffuse interstitial keratitis |
| H16.32 | Diffuse interstitial keratitis |
| H16.321 | Diffuse interstitial keratitis, right eye |
| H16.321 | Diffuse interstitial keratitis, right eye |
| H16.322 | Diffuse interstitial keratitis, left eye |
| H16.322 | Diffuse interstitial keratitis, left eye |
| H16.323 | Diffuse interstitial keratitis, bilateral |
| H16.323 | Diffuse interstitial keratitis, bilateral |
| H16.329 | Diffuse interstitial keratitis, unspecified eye |
| H16.329 | Diffuse interstitial keratitis, unspecified eye |
| H16.33 | Sclerosing keratitis |
| H16.331 | Sclerosing keratitis, right eye |
| H16.332 | Sclerosing keratitis, left eye |
| H16.333 | Sclerosing keratitis, bilateral |
| H16.339 | Sclerosing keratitis, unspecified eye |
| H16.39 | Other interstitial and deep keratitis |
| H16.39 | Other interstitial and deep keratitis |
| H16.391 | Other interstitial and deep keratitis, right eye |
| H16.391 | Other interstitial and deep keratitis, right eye |
| H16.392 | Other interstitial and deep keratitis, left eye |
| H16.392 | Other interstitial and deep keratitis, left eye |
| H16.393 | Other interstitial and deep keratitis, bilateral |
| H16.393 | Other interstitial and deep keratitis, bilateral |
| H16.399 | Other interstitial and deep keratitis, unspecified eye |
| H16.399 | Other interstitial and deep keratitis, unspecified eye |
| H16.8 | Other keratitis |
| H16.8 | Other keratitis |
| H16.9 | Unspecified keratitis |
| S05.00xA | Injury of conjunctiva and corneal abrasion without foreign body, unspecified eye, initial encounter |
| S05.01xA | Injury of conjunctiva and corneal abrasion without foreign body, right eye, initial encounter |
| S05.02xA | Injury of conjunctiva and corneal abrasion without foreign body, left eye, initial encounter |
Formulary Reference Tool