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AMILORIDE HCL (AMILORIDE HCL)
- Edema
- Peripheral edema due to chronic heart failure
- Hypertension
amiloride 5 mg tablet
- 1 tablet (5 mg) by oral route once daily with food
Edema
- 1 tablet (5 mg) by oral route once daily with food
- 2 tablets (10 mg) by oral route once daily with food
- 3 tablets (15 mg) by oral route once daily with food
- 4 tablets (20 mg) by oral route once daily with food
Hypertension
- 1 tablet (5 mg) by oral route once daily with food
- 2 tablets (10 mg) by oral route once daily with food
- 3 tablets (15 mg) by oral route once daily with food
- 4 tablets (20 mg) by oral route once daily with food
Peripheral edema due to chronic heart failure
- 1 tablet (5 mg) by oral route once daily with food
- 2 tablets (10 mg) by oral route once daily with food
- Astagraf Xl
- cyclosporine
- cyclosporine modified
- Gengraf
- Hecoria
- Neoral
- Prograf
- Sandimmune
- tacrolimus
Contraindicated
- Alka-seltzer Gold
- Ceralyte-70
- Ceraors 75
- Cerasport
- Cerasport Ex1
- Curad Enema
- Cytra K Crystals
- Cytra-3
- Cytra-k
- Disposable Enema
- DM-GG-potassium citrate
- Effer-k
- Enema
- Enema Disposable
- eplerenone
- Fleet Enema
- Fleet Enema Extra
- Fleet Pediatric
- Hyperlyte Cr
- Inspra
- K-effervescent
- K-tab
- Kaochlor
- Klor-con
- Klor-con 10
- Klor-con M10
- Klor-con M15
- Klor-con M20
- Klor-con/ef
- Medi-lyte
- Nano Vm T/f
- Nutrilyte Ii
- Oral Saline Laxative
- Osmoprep
- Pedialyte
- Pediatric Electrolyte
- pediatric multivit #18-iron-FA
- PEG 3350-bowel 2,two part prep
- Phosphate Laxative
- pot & sod citrate-citric acid
- potassium
- potassium bicarb & chloride
- potassium bicarb-citric acid
- potassium chlorid-D5-0.45%NaCl
- potassium chloride
- potassium chloride in 0.9%NaCl
- potassium chloride in D5W
- potassium chloride in LR-D5
- potassium chloride-0.45 % NaCl
- potassium chloride-D5-0.2%NaCl
- potassium chloride-D5-0.3%NaCl
- potassium chloride-D5-0.9%NaCl
- potassium citrate
- potassium citrate-citric acid
- potassium Cl-calcium phos-mag
- potassium gluconate
- potassium phosphate dibasic
- Preparation Cleansing
- Ready-to-use Enema
- Reclast
- sod & pot chlorid-sod cit-rice
- sod phos mono-sod phos dibasic
- sodium & potassium bicarbonate
- sodium Cl-potassium chloride
- sodium phosphates
- sodium-K+-mag-Ca-chlor-acetate
- sodium-potas-chloride-dextrose
- Sorbutuss
- Suclear
- Taron-crystals
- Theralith Xr
- Thermotabs
- Tpn Electrolytes
- Tpn Electrolytes Ii
- Tricitrates
- Urocit-k 10
- Urocit-k 15
- Urocit-k 5
- vit B6-mag cit & ox-potass cit
- zoledronic acid
- zoledronic acid-mannitol-water
- Zometa
Severe
Moderate
- Accupril
- Accuretic
- Aceon
- Advil
- Advil Allergy Sinus
- Advil Allergy-congestion Rlf
- Advil Cold & Sinus
- Advil Congestion Relief
- Advil Liqui-gel
- Advil Migraine
- Advil Pm
- Advil Pm Liqui-gels
- Aleve
- Aleve Cold & Sinus
- Aleve Sinus & Headache
- Aleve-d Sinus & Cold
- Aleve-d Sinus & Headache
- All Day Pain Relief
- All Day Pain Relief Sinus & Co
- All Day Relief
- Altace
- amlodipine-benazepril
- amlodipine-olmesartan
- amlodipine-valsartan
- amlodipine-valsartan-hcthiazid
- Anaprox
- Anaprox Ds
- Angeliq
- Ansaid
- Arthrotec 50
- Atacand
- Atacand Hct
- Avalide
- Avapro
- azilsartan med-chlorthalidone
- azilsartan medoxomil
- Azor
- benazepril
- benazepril-hydrochlorothiazide
- Benicar
- Benicar Hct
- Beyaz
- Caldolor
- Cambia
- candesartan
- candesartan-hydrochlorothiazid
- captopril
- captopril-hydrochlorothiazide
- Cataflam
- Celebrex
- celecoxib
- Child Ibuprofen
- Children's Advil
- Children's Ibu-drops
- Children's Ibuprofen
- Children's Medi-profen
- Children's Motrin
- Children's Profen Ib
- chlorphen-phenyleph-ibuprofen
- chlorphen-pseudoeph-ibuprofen
- Cold & Sinus Pain Relief
- Cold-sinus Relief
- Cozaar
- Daypro
- diclofenac epolamine
- diclofenac potassium
- diclofenac sodium
- diclofenac submicronized
- diclofenac-misoprostol
- Diovan Hct
- drospirenone-e.estradiol-lm.FA
- drospirenone-estradiol
- drospirenone-ethinyl estradiol
- Duexis
- Ec-naprosyn
- Edarbi
- Edarbyclor
- enalapril maleate
- enalapril-hydrochlorothiazide
- enalaprilat
- Epaned
- eprosartan
- eprosartan-hydrochlorothiazide
- etodolac
- Exforge
- Exforge Hct
- Feldene
- fenoprofen
- Flanax
- Flector
- flurbiprofen
- fosinopril
- fosinopril-hydrochlorothiazide
- Gianvi (28)
- hydrocodone-ibuprofen
- Hyzaar
- I-prin
- Ibu-drops
- Ibudone
- ibuprofen
- Ibuprofen Cold
- Ibuprofen Cold-sinus(with Pse)
- Ibuprofen Ib
- Ibuprofen Jr Strength
- ibuprofen lysine (PF)
- Ibuprofen Pm
- ibuprofen-diphenhydramine
- ibuprofen-diphenhydramine HCl
- ibuprofen-famotidine
- ibuprofen-oxycodone
- ibuprofen-phenylephrine HCl
- Indocin
- indomethacin
- indomethacin sodium
- Infant's Ibuprofen
- Infant's Medi-profen
- Infant's Motrin
- Infants Ibu-drops
- Infants Profenib
- irbesartan
- irbesartan-hydrochlorothiazide
- ketoprofen
- ketorolac
- lisinopril
- lisinopril-hydrochlorothiazide
- Loryna (28)
- losartan
- losartan-hydrochlorothiazide
- Lotensin
- Lotrel
- Mavik
- Medi-profen
- Mediproxen
- mefenamic acid
- meloxicam
- Micardis
- Micardis Hct
- Midol (naproxen)
- Mobic
- moexipril
- moexipril-hydrochlorothiazide
- Motrin Ib
- Motrin Pm
- nabumetone
- Nalfon
- Naprelan Cr
- Naprosyn
- naproxen
- naproxen sodium
- naproxen-esomeprazole
- naproxen-pseudoephedrine
- Neoprofen (ibuprofen Lysn)(pf)
- Ocella
- olmesartan
- olmesartan-amlodipin-hcthiazid
- olmesartan-hydrochlorothiazide
- oxaprozin
- Pennsaid
- perindopril erbumine
- piroxicam
- Ponstel
- Prinivil
- Provil
- pseudoephedrine-ibuprofen
- quinapril
- quinapril-hydrochlorothiazide
- ramipril
- Reprexain
- Safyral
- Sinus & Cold-d
- Solaraze
- Sprix
- sulindac
- Syeda
- Tarka
- telmisartan
- telmisartan-amlodipine
- telmisartan-hydrochlorothiazid
- Teveten
- Teveten Hct
- tolmetin
- trandolapril
- trandolapril-verapamil
- Tribenzor
- Twynsta
- Uniretic
- Univasc
- valsartan-hydrochlorothiazide
- Vaseretic
- Vasotec
- Vestura (28)
- Vicoprofen
- Vimovo
- Voltaren-xr
- Wal-profen
- Wal-profen Cold-sinus
- Wal-proxen
- Yasmin (28)
- Yaz 28
- Zarah
- Zestoretic
- Zestril
- Zipsor
- Zorvolex
- Hyperkalemia
Contraindicated
- Diabetic nephropathy
- Disease of liver
- Kidney disease with reduction in GFR
- Oliguria
Severe
Moderate
- Acidosis
- Diabetes mellitus
- Hyponatremia
AMILORIDE HCL (AMILORIDE HCL)
- Edema
- Peripheral edema due to chronic heart failure
- Hypertension
- Hyperkalemia
- None
More Frequent
Severe
Less Severe
- Encephalopathy
- Abnormal sexual function
- Acute abdominal pain
- Anorexia
- Constipation
- Cough
- Cramps
- Diarrhea
- Dizziness
- Erectile dysfunction
- Fatigue
- Flatulence
- Gastrointestinal irritation
- General weakness
- Headache disorder
- Hyponatremia
- Nausea
- Vomiting
Less Frequent
Severe
Less Severe
Rare / Very Rare
Severe
- Abnormal hepatic function tests
- Anaphylaxis
- Angina
- Aplastic anemia
- Cardiac arrhythmia
- Dyspnea
- Gastrointestinal hemorrhage
- Jaundice
- Neutropenic disorder
- Ocular hypertension
- Orthostatic hypotension
Less Severe
- Acute confusion
- Alopecia
- Arthralgias
- Back pain
- Bladder irritability
- Chest pain
- Depression
- Drowsy
- Dysuria
- Gynecomastia
- Heartburn
- Increased urinary frequency
- Insomnia
- Leg pain
- Libido changes
- Nasal congestion
- Neck pain
- Nervousness
- Palpitations
- Paresthesia
- Polydipsia
- Polyuria
- Pruritus of skin
- Skin rash
- Tinnitus
- Tremor
- Vertigo
- Visual changes
- Xerostomia
Contraindicated
None
Severe Precaution
None
Management or Monitoring Precaution
Amiloride
Safety and efficacy not established in pediatrics.
- 1 Day – 18 Years
- Safety and efficacy not established in pediatrics.
Amiloride Hydrochloride
- Severity Level:
B
- Additional Notes:
Contraindicated
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Precaution Exists
Amiloride Hydrochloride
Animal studies suggest excretion occurs; no human studies data available.
| General | Excretion Potential | Effect on Infant | Notes |
| Evaluate use carefully | Unknown | Not known; no or inclusive data | Animal studies suggest excretion occurs; no human studies data available. |
No Known Risk
None
| General | Excretion Potential | Effect on Infant | Notes |
| None |
Contraindicated
None
Precaution Exists
Amiloride
Renal-Increased risk for hyperkalemia and hyponatremia in patients with severe renal impairment due to potassium sparing effects. Avoid with CrCl < 30 mL/min.
| Organ / System | HEP | REN | CARD | ENDO | NEURO / PSYCH | PULM |
| Increased Risk / Adverse Effects | Y | N | N | N | N | N |
BEERS: Y HEDIS: N STOPP: Y
No Known Risk
None
- This medication can cause high potassium levels (hyperkalemia). This effect is more likely to occur in older adults and in patients with kidney disease, diabetes, or a serious illness. Potassium levels must be closely monitored on a regular basis while taking this medication.<br /><br />If not treated, very high potassium levels can sometimes be fatal. Tell your doctor right away if you develop any symptoms of high potassium levels, including muscle weakness, slow/irregular heartbeat, numb/tingling skin.
| Edema | |
| R60 | Edema, not elsewhere classified |
| R60.0 | Localized edema |
| R60.1 | Generalized edema |
| R60.9 | Edema, unspecified |
| Hypertension | |
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| Peripheral edema due to chronic heart failure | |
| R60 | Edema, not elsewhere classified |
| R60.9 | Edema, unspecified |
| 0-9 | A-Z |
|---|---|
| I10 | Essential (primary) hypertension |
| I11 | Hypertensive heart disease |
| I11.0 | Hypertensive heart disease with heart failure |
| I11.9 | Hypertensive heart disease without heart failure |
| I12 | Hypertensive chronic kidney disease |
| I12.0 | Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease |
| I12.9 | Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13 | Hypertensive heart and chronic kidney disease |
| I13.0 | Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.1 | Hypertensive heart and chronic kidney disease without heart failure |
| I13.10 | Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease |
| I13.11 | Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease |
| I13.2 | Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease |
| I15.1 | Hypertension secondary to other renal disorders |
| R60 | Edema, not elsewhere classified |
| R60 | Edema, not elsewhere classified |
| R60.0 | Localized edema |
| R60.1 | Generalized edema |
| R60.9 | Edema, unspecified |
| R60.9 | Edema, unspecified |
Formulary Reference Tool