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Drug overview for OBAGI-C THERAPY NIGHT (hydroquinone/ascorbic acid/vitamin e acetate):
Generic name: HYDROQUINONE/ASCORBIC ACID/VITAMIN E ACETATE (hi-dro-KWIN-own)
Drug class:
Therapeutic class: Dermatological
Hydroquinone, which is structurally related to monobenzone, is a depigmenting agent.
No enhanced Uses information available for this drug.
Generic name: HYDROQUINONE/ASCORBIC ACID/VITAMIN E ACETATE (hi-dro-KWIN-own)
Drug class:
Therapeutic class: Dermatological
Hydroquinone, which is structurally related to monobenzone, is a depigmenting agent.
No enhanced Uses information available for this drug.
DRUG IMAGES
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The following indications for OBAGI-C THERAPY NIGHT (hydroquinone/ascorbic acid/vitamin e acetate) have been approved by the FDA:
Indications:
Chloasma
Dyschromia
Professional Synonyms:
Anomalous pigmentation of the skin
Discoloration of skin
Discolored skin
Mask of pregnancy
Melanoderma chloasma
Moth patch
Pigmentation alteration
Skin pigmentation disorder
Indications:
Chloasma
Dyschromia
Professional Synonyms:
Anomalous pigmentation of the skin
Discoloration of skin
Discolored skin
Mask of pregnancy
Melanoderma chloasma
Moth patch
Pigmentation alteration
Skin pigmentation disorder
The following dosing information is available for OBAGI-C THERAPY NIGHT (hydroquinone/ascorbic acid/vitamin e acetate):
To depigment hyperpigmented skin, a thin layer of hydroquinone cream or solution should be applied uniformly and rubbed into the pigmented area twice daily, in the morning and evening. Application of the drug should be limited to an area equal to that of the face and neck or hands and arms. Exposure to sunlight should be minimized during treatment (See Cautions: Precautions and Contraindications); the opaque base in some hydroquinone preparations (Eldopaque(R), Eldopaque Forte(R)) may provide sufficient protection from sunlight.
If no depigmentation is evident after 2 months of hydroquinone treatment, the drug should be discontinued. When the desired degree of depigmentation is obtained, hydroquinone should be applied only as often as needed to maintain depigmentation.
If no depigmentation is evident after 2 months of hydroquinone treatment, the drug should be discontinued. When the desired degree of depigmentation is obtained, hydroquinone should be applied only as often as needed to maintain depigmentation.
Preparations containing 2-4% hydroquinone are applied topically. Hydroquinone should not be administered orally.
| DRUG LABEL | DOSING TYPE | DOSING INSTRUCTIONS |
|---|---|---|
| OBAGI-C THERAPY NIGHT CREAM | Maintenance | Adults apply a thin layer to the affected area(s) by topical route 1-2 times daily |
No generic dosing information available.
The following drug interaction information is available for OBAGI-C THERAPY NIGHT (hydroquinone/ascorbic acid/vitamin e acetate):
There are 0 contraindications.
There are 0 severe interactions.
There are 0 moderate interactions.
The following contraindication information is available for OBAGI-C THERAPY NIGHT (hydroquinone/ascorbic acid/vitamin e acetate):
Drug contraindication overview.
No enhanced Contraindications information available for this drug.
No enhanced Contraindications information available for this drug.
There are 0 contraindications.
There are 1 severe contraindications.
Adequate patient monitoring is recommended for safer drug use.
| Severe List |
|---|
| Sunburn |
There are 0 moderate contraindications.
The following adverse reaction information is available for OBAGI-C THERAPY NIGHT (hydroquinone/ascorbic acid/vitamin e acetate):
Adverse reaction overview.
No enhanced Common Adverse Effects information available for this drug.
No enhanced Common Adverse Effects information available for this drug.
There are 3 severe adverse reactions.
| More Frequent | Less Frequent |
|---|---|
| None. |
Contact dermatitis Hypersensitivity drug reaction |
| Rare/Very Rare |
|---|
|
Dyschromia |
There are 0 less severe adverse reactions.
The following precautions are available for OBAGI-C THERAPY NIGHT (hydroquinone/ascorbic acid/vitamin e acetate):
No enhanced Pediatric Use information available for this drug.
Contraindicated
Severe Precaution
Management or Monitoring Precaution
Contraindicated
| None |
Severe Precaution
| None |
Management or Monitoring Precaution
| None |
Reproductive studies in animals have not been performed with topical hydroquinone. It is not known whether hydroquinone can cause fetal harm when used topically by pregnant women. Topical hydroquinone should be used during pregnancy only when clearly needed.
Since it is not known if topical hydroquinone is absorbed or distributed into human milk, the drug should be used with caution in nursing women.
Precaution Exists
Precaution exists. (No data or inconclusive human data.) Use of this drug by breast feeding mothers should be evaluated carefully.
No Known Risk
No known risk. This drug has no known risks to nursing infants and does not adversely affect lactation.
Precaution Exists
Precaution exists. (No data or inconclusive human data.) Use of this drug by breast feeding mothers should be evaluated carefully.
| Drug Name | Excretion Potential | Effect on Infant | Notes |
|---|---|---|---|
| Hydroquinone | Unknown. It is unknown whether the drug is excreted in human breast milk. | It is not known whether this drug has an adverse effect on the nursing infant. (No data or inconclusive human data) | Insufficient human data available |
No Known Risk
No known risk. This drug has no known risks to nursing infants and does not adversely affect lactation.
| Drug Name | Excretion Potential | Effect on Infant | Notes |
|---|---|---|---|
| Vitamin E (topical) | Excreted.This drug is known to be excreted in human breast milk. | This drug has been shown not to have an adverse effect on the nursing infant. | Avoid using products w/high conc in nipple area, risk of inc level in infant |
No enhanced Geriatric Use information available for this drug.
The following prioritized warning is available for OBAGI-C THERAPY NIGHT (hydroquinone/ascorbic acid/vitamin e acetate):
No warning message for this drug.
No warning message for this drug.
The following icd codes are available for OBAGI-C THERAPY NIGHT (hydroquinone/ascorbic acid/vitamin e acetate)'s list of indications:
| Chloasma | |
| H02.71 | Chloasma of eyelid and periocular area |
| H02.711 | Chloasma of right upper eyelid and periocular area |
| H02.712 | Chloasma of right lower eyelid and periocular area |
| H02.713 | Chloasma of right eye, unspecified eyelid and periocular area |
| H02.714 | Chloasma of left upper eyelid and periocular area |
| H02.715 | Chloasma of left lower eyelid and periocular area |
| H02.716 | Chloasma of left eye, unspecified eyelid and periocular area |
| H02.719 | Chloasma of unspecified eye, unspecified eyelid and periocular area |
| L81.1 | Chloasma |
| Dyschromia | |
| L81.9 | Disorder of pigmentation, unspecified |
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