METOPROLOL-HYDROCHLOROTHIAZIDE (METOPROLOL TARTRATE/HYDROCHLOROTHIAZIDE)

Moderate

• acarbose

• Aceta-gesic

• Acetadryl

• Acetaminophen Pm

• Acetaminophen Pm Extra Str

• Acid Control (ranitidine)

• Acid Reducer (cimetidine)

• Acid Reducer (ranitidine)

• Acid Relief (cimetidine)

• Adalat Cc

• Adult Robitussin Night M-s Cld

• Advil

• Advil Allergy Sinus

• Advil Allergy-congestion Rlf

• Advil Cold & Sinus

• Advil Congestion Relief

• Advil Liqui-gel

• Advil Migraine

• Advil Pm

• Advil Pm Liqui-gels

• Afeditab Cr

• Alagesic Lq

• Aldex-ct

• Aler-cap

• Aler-tab

• Aleve

• Aleve Cold & Sinus

• Aleve Sinus & Headache

• Aleve-d Sinus & Cold

• Aleve-d Sinus & Headache

• Alka-seltzer Plus Allergy

• Alka-seltzer Pm

• All Day Pain Relief

• All Day Pain Relief Sinus & Co

• All Day Relief

• Aller-g-time

• Allergy (diphenhydramine)

• Allergy M-s Nighttime

• Allergy Medication

• Allergy Medicine

• Allergy Plus Severe Sinus Ha

• Allergy Relief(diphenhydramin)

• Allergy Relief-sinus Headache

• Allergy Severe

• Allergy Sinus Headache

• Allergy-d

• Allergy-sinus

• Altavera (28)

• Alyacen 1/35 (28)

• Alyacen 7/7/7 (28)

• Amaryl

• Amethia

• Amethia Lo

• Amethyst

• amiodarone

• amiodarone in dextrose,iso-osm

• amobarbital

• Amytal

• Anaprox

• Anaprox Ds

• Ansaid

• Antihist

• Antihistamine

• Apidra

• Apidra Solostar

• Aplenzin

• Apri

• Aranelle (28)

• Ascomp With Codeine

• aspirin-diphenhydramine

• aspirin-diphenhydramine citrat

• Aubra

• Aviane

• Azurette (28)

• Balziva (28)

• Banophen

• Banophen Allergy

• Bayer Pm

• Belladonna-phenobarbital

• Belviq

• Benadryl

• Benadryl Allergy

• Beyaz

• Bidil

• Brevicon (28)

• Briellyn

• Brisdelle

• Bupap

• Buproban

• bupropion HBr

• bupropion HCl

• butabarbital

• Butalbital Compound W/codeine

• Butalbital Compound-codeine

• butalbital-acetaminop-caf-cod

• butalbital-acetaminophen

• butalbital-acetaminophen-caff

• butalbital-aspirin-caffeine

• Butisol

• Calan

• Calan Sr

• Caldolor

• Camila

• Camrese

• Camrese Lo

• Capacet

• Cardizem

• Cardizem Cd

• Cardizem La

• Cartia Xt

• Caziant (28)

• Celebrex

• celecoxib

• Celexa

• Chateal

• Child Allergy Relief (diphen)

• Child Delsym Cough+cold

• Child Ibuprofen

• Child's Benadryl-d Allergy-sin

• Children Night Time Cold-cough

• Children's Advil

• Children's Allergy

• Children's Complete Allergy

• Children's Ibu-drops

• Children's Ibuprofen

• Children's Medi-profen

• Children's Motrin

• Children's Mucinex Night Time

• Children's Profen Ib

• Children's Wal-dryl Allergy

• Childs Plus Cold & Allergy

• Childs Triacting Cold & Cough

• chlorphen-phenyleph-ibuprofen

• chlorphen-pseudoeph-ibuprofen

• cholestyramine (with sugar)

• Cholestyramine Light

• cholestyramine-aspartame

• cimetidine

• cinacalcet

• citalopram

• codeine-butalbital-ASA-caff

• Cold & Cough

• Cold & Sinus Pain Relief

• Cold Relief

• Cold-sinus Relief

• Colestid

• Colestid Flavored

• colestipol

• Complete Allergy

• Complete Allergy Medicine

• Compoz

• conj estrogens-bazedoxifene

• Cordarone

• Cough & Severe Cold

• Cryselle (28)

• Cyclafem 1/35 (28)

• Cyclafem 7/7/7 (28)

• Cyclessa (28)

• Cymbalta

• Dasetta 1/35 (28)

• Dasetta 7/7/7 (28)

• Daysee

• Delsym Cough+cold Nighttime

• Depo-provera

• Depo-subq Provera 104

• Deprizine

• desog-e.estradiol/e.estradiol

• Desogen

• desogestrel-ethinyl estradiol

• dextromethorphan-quinidine

• Diabeta

• Diabetic Tussin Night Time

• diazoxide

• Dicopanol

• Digox

• digoxin

• Dilacor Xr

• Dilt-xr

• diltiazem HCl

• Dimetapp Cold-congestion

• Diphedryl

• Diphedryl Allergy

• Diphenhist

• diphenhy HCl-PE-DM-acetamin-GG

• diphenhyd-PE-acetaminophen

• diphenhyd-PE-DM-acetaminophen

• diphenhydram-PE-acetaminoph-GG

• diphenhydram-PSE-acetaminophen

• diphenhydramine HCl

• diphenhydramine-acetaminophen

• diphenhydramine-DM-acetamin

• diphenhydramine-phenylephrine

• Donnatal

• dronedarone

• drospirenone-e.estradiol-lm.FA

• drospirenone-ethinyl estradiol

• Duavee

• Duetact

• Duexis

• duloxetine

• Ec-naprosyn

• Elinest

• Emoquette

• Enpresse

• Enskyce

• Errin

• escitalopram oxalate

• Esgic

• Estarylla

• estradiol valerate-dienogest

• Estrostep Fe-28

• ethynodiol diac-eth estradiol

• etonogestrel

• etonogestrel-ethinyl estradiol

• Ex-strength Medi-tabs Pm

• Ez Nite Sleep

• Ez Use Joint-tunnel-trigger

• Falmina (28)

• Feldene

• Femcon Fe

• Fioricet

• Fioricet With Codeine

• Fiorinal

• Fiorinal-codeine #3

• First-bxn

• First-duke's

• First-mary's Mouthwash

• Flanax

• Flu & Severe Cold-nighttime

• Flu & Sore Throat Relief

• Flu Formula Daytime-nighttime

• Flu Relief Therapy Nighttime

• Flu-severe Cold-cough

• fluoxetine

• flurbiprofen

• Forfivo Xl

• Generess Fe

• Gianvi (28)

• Gildagia

• Gildess

• Gildess Fe

• Gleevec

• glimepiride

• glipizide

• glipizide-metformin

• Glucotrol

• Glucotrol Xl

• Glucovance

• glyburide

• glyburide micronized

• glyburide-metformin

• Glynase

• Glyset

• Goody's Pm

• Headache Pm

• Headache Relief Pm

• Heartburn Relief

• Heartburn Relief (ranitidine)

• Heather

• Humalog

• Humalog Kwikpen

• Humalog Mix 50-50

• Humalog Mix 50-50 Kwikpen

• Humalog Mix 75-25

• Humalog Mix 75-25 Kwikpen

• Humulin 70/30

• Humulin N

• Humulin N Kwikpen

• Humulin R

• Humulin R U-500 "Concentrated"

• hydralazine

• hydrocodone-ibuprofen

• hydroxychloroquine

• I-prin

• Ibu-drops

• Ibudone

• ibuprofen

• Ibuprofen Cold

• Ibuprofen Cold-sinus(with Pse)

• Ibuprofen Ib

• Ibuprofen Jr Strength

• ibuprofen lysine (PF)

• Ibuprofen Pm

• ibuprofen-diphenhydramine

• ibuprofen-diphenhydramine HCl

• ibuprofen-famotidine

• ibuprofen-oxycodone

• ibuprofen-phenylephrine HCl

• imatinib

• Indocin

• indomethacin

• indomethacin sodium

• Infant's Ibuprofen

• Infant's Medi-profen

• Infant's Motrin

• Infants Ibu-drops

• Infants Profenib

• insulin asp prt-insulin aspart

• insulin aspart

• insulin detemir

• insulin glargine

• insulin glulisine

• insulin lispro

• insulin lispro protam-lispro

• insulin NPH and regular human

• insulin regular hum U-500 conc

• insulin regular human

• Intense Cold & Flu

• Introvale

• isoniazid-rifamp-pyrazinamide

• isosorbide-hydralazine

• Jencycla

• Jolessa

• Jolivette

• Junel 1.5/30 (21)

• Junel 1/20 (21)

• Junel Fe 1.5/30 (28)

• Junel Fe 1/20 (28)

• Kariva (28)

• Kelnor 1/35 (28)

• Kurvelo

• L norgest&E estradiol-E estrad

• Lamisil

• Lanoxin

• Lanoxin Pediatric

• Lantus

• Lantus Solostar

• Larin 1/20 (21)

• Larin Fe

• Leena 28

• Lessina

• Levemir

• Levemir Flexpen

• Levonest (28)

• levonorg-eth estrad triphasic

• levonorgestrel

• levonorgestrel-ethinyl estrad

• Levora 0.15/30 (28)

• Levora-28

• Lexapro

• lidocaine (PF)

• lidocaine in D5W (PF)

• Lo Loestrin Fe

• Loestrin 1.5/30 (21)

• Loestrin 1/20 (21)

• Loestrin Fe 1.5/30 (28)

• Loestrin Fe 1/20 (28)

• Lomedia 24 Fe

• lorcaserin

• Loryna (28)

• Loseasonique

• Low-ogestrel (28)

• Luminal

• Lutera (28)

• Lyza

• Mapap Pm

• Margesic

• Marlissa

• Marten-tab

• Matzim La

• Medi-phedryl

• Medi-profen

• Medi-tabs Pm

• Mediproxen

• medroxyprogesterone

• mefloquine

• meloxicam

• methimazole

• Microgestin 1.5/30 (21)

• Microgestin 1/20 (21)

• Microgestin Fe 1.5/30 (28)

• Microgestin Fe 1/20 (28)

• Midol (naproxen)

• Midol Pm

• miglitol

• Minastrin 24 Fe

• Minipress

• mirabegron

• Mircette (28)

• Mirena

• Mobic

• Modicon (28)

• Mono-linyah

• Mononessa (28)

• Motrin Ib

• Motrin Pm

• Mucinex Fast-max Nite Cold-flu

• Mucinex Sinus-max Day-night

• Multaq

• My Way

• Mycobutin

• Myrbetriq

• Mysoline

• Myzilra

• Naprelan Cr

• Naprosyn

• naproxen

• naproxen sodium

• naproxen-esomeprazole

• naproxen-pseudoephedrine

• Natazia

• nateglinide

• Necon 0.5/35 (28)

• Necon 1/35 (28)

• Necon 1/50 (28)

• Necon 10/11 (28)

• Necon 7/7/7 (28)

• Nembutal Sodium

• Neoprofen (ibuprofen Lysn)(pf)

• Nexplanon

• Next Choice One Dose

• Nexterone

• Nifedical Xl

• nifedipine

• Nightime Sleep

• Nighttime Cough-cold

• Nighttime Sleep Aid (diphen)

• Non-asa Ex St Pain/sleep Aid

• Non-aspirin Allergy Sinus Pm

• Non-aspirin Flu

• Non-aspirin Nightime

• Non-aspirin Pain Relief Pm

• Non-aspirin Pm

• Nor-qd

• Nora-be

• norelgestrom-ethinyl estradiol

• noreth-ethinyl estradiol-iron

• norethin-e.estradiol triphasic

• norethin-eth estrad biphasic

• norethindrone (contraceptive)

• norethindrone ac-eth estradiol

• norethindrone-e.estradiol-iron

• norethindrone-ethin estradiol

• norethindrone-mestranol

• norgestimate-ethinyl estradiol

• norgestrel-ethinyl estradiol

• Norinyl 1+35 (28)

• Norinyl 1+50 (28)

• Nortrel 0.5/35 (28)

• Nortrel 1/35 (21)

• Nortrel 1/35 (28)

• Nortrel 7/7/7 (28)

• Novolin 70/30

• Novolin N

• Novolin R

• Novolog

• Novolog Flexpen

• Novolog Mix 70-30

• Novolog Mix 70-30 Flexpen

• Novolog Penfill

• NPH insulin human recomb

• Nuedexta

• Nuvaring

• nystat-lidocaine-diphenhyd HCl

• nystatin-hydrocortisone-diphen

• nystatin-TCN-HC-diphenhydramin

• Nytol

• Ocella

• Ogestrel (28)

• olanzapine-fluoxetine

• Ormir

• Orsythia

• Ortho Evra

• Ortho Micronor

• Ortho Tri-cyclen (28)

• Ortho Tri-cyclen Lo (28)

• Ortho-cept (28)

• Ortho-cyclen (28)

• Ortho-novum 1/35 (28)

• Ortho-novum 7/7/7 (28)

• Ovcon-35 (28)

• Pacerone

• Pain & Sleep

• Pain Medicine P.m.

• Pain Relief Pm

• Pain Relief Pm Rapid Release

• Pain Reliever Am/pm

• Pain Reliever Pm

• Pain Reliever Pm Ex-strength

• paroxetine HCl

• paroxetine mesylate

• Paxil

• Paxil Cr

• pentobarbital sodium

• Percogesic

• Percogesic Extra Strength

• Pexeva

• Pharbedryl

• phenobarb-hyoscy-atropine-scop

• phenobarbital

• phenobarbital sodium

• Philith

• Pimtrea (28)

• pioglitazone-glimepiride

• Pirmella

• piroxicam

• Plan B One-step

• Plaquenil

• Pm Pain Reliever

• Portia

• prazosin

• Precose

• Prevalite

• Previfem

• Priftin

• primidone

• Procardia

• Procardia Xl

• Proglycem

• propafenone

• propylthiouracil

• Provil

• Prozac

• Prozac Weekly

• pseudoephedrine-ibuprofen

• Q-dryl

• Quartette

• Quasense

• Quenalin

• Questran

• Questran Light

• quinidine gluconate

• quinidine sulfate

• ranitidine HCl

• Reclipsen (28)

• Reprexain

• Rest Simply Nighttime Sleep

• Restfully Sleep

• rifabutin

• Rifadin

• Rifamate

• rifampin

• rifampin-isoniazid

• rifapentine

• Rifater

• Rythmol

• Safyral

• Sarafem

• Seasonique

• secobarbital sodium

• Seconal Sodium

• Sensipar

• sertraline

• Severe Allergy

• Severe Allergy-sinus Headache

• Severe Cold (diphen-pe-acetam)

• Severe Cold Pe

• Siladryl Sa

• Silphen Cough

• Simply Sleep

• Sinus & Cold-d

• Sleep

• Sleep Aid (diphenhydramine)

• Sleep Aid Max Str (diphenhydr)

• Sleep Ii

• Sleep Tablet (diphenhydramine)

• Sleep Time

• Sleep-tabs

• Sleepgels

• Sleeping

• Sprintec (28)

• Sronyx

• Starlix

• sulindac

• Suphedrine Pe Day-night

• Syeda

• Symbyax

• Tagamet Hb

• Tapazole

• Tarka

• Taztia Xt

• Tencon

• terbinafine

• Theraflu Nighttime Cold-cough

• Tiazac

• Tilia Fe

• tolazamide

• tolbutamide

• trandolapril-verapamil

• Tri-estarylla

• Tri-legest Fe

• Tri-linyah

• Tri-norinyl (28)

• Tri-previfem (28)

• Tri-sprintec (28)

• triamcinolone-lidocaine

• Triaminic Cold & Cough Nt (pe)

• Trinessa (28)

• Trivora (28)

• Unisom Sleepgels

• Unisom Sleepmelts

• Valu-dryl

• Valu-dryl Allergy

• Valu-dryl Allergy-sinus-head

• Valu-dryl Child's Allergy

• Velivet Triphasic Regimen (28)

• verapamil

• Verelan

• Verelan Pm

• Vestura (28)

• Vicoprofen

• Vimovo

• Viorele (28)

• Vyfemla (28)

• Wal-dryl Allergy

• Wal-dryl Severe Allergy-sinus

• Wal-dryl-d Allergy & Sinus

• Wal-flu Night Severe Cold

• Wal-nadol Pm

• Wal-phed Pe Nighttime Cold

• Wal-phed Pe Severe Cold

• Wal-profen

• Wal-profen Cold-sinus

• Wal-proxen

• Wal-sleep Z

• Wal-som

• Wal-zan 150

• Wellbutrin

• Wellbutrin Sr

• Wellbutrin Xl

• Wera (28)

• Wymzya Fe

• Xylocaine (cardiac) (pf)

• Yasmin (28)

• Yaz 28

• Z-sleep

• Zantac

• Zantac Maximum Strength

• Zarah

• Zebutal

• Zenchent (28)

• Zenchent Fe

• Zeosa

• Zoloft

• Zovia 1/35E (28)

• Zovia 1/50E (28)

• Zyban

• Zzzquil

Moderate

• Basal cell carcinoma of skin

• Bronchospastic pulmonary disease

• Depression

• Diabetes mellitus

• Hypercalcemia

• Hypercholesterolemia

• Hyperparathyroidism

• Hypoglycemic disorder

• Myasthenia gravis

• Pheochromocytoma

• Psoriasis

• Raynaud's phenomenon

• Squamous cell carcinoma of skin

• Sympathectomy

• Systemic lupus erythematosus

Hydrochlorothiazide

• Severity Level:

  B

• Additional Notes: Not recommended in pre-eclampsia and other pregnancy-induced hypertension.

Metoprolol

• Severity Level:

  C

• Additional Notes: Reports of intrauterine growth retardation; monitor fetus/infant heart rate

Contraindicated

None

General	Excretion Potential	Effect on Infant	Notes
			None

Precaution Exists

Hydrochlorothiazide

Limited amounts excreted with no known adverse effects in infant.

Limited data suggest minimal excretion; monitor for bradycardia & hypotension

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Not known; no or inclusive data	Limited amounts excreted with no known adverse effects in infant.

Metoprolol

Limited amounts excreted with no known adverse effects in infant.

Limited data suggest minimal excretion; monitor for bradycardia & hypotension

General	Excretion Potential	Effect on Infant	Notes
Evaluate use carefully	Excreted	Not known; no or inclusive data	Limited data suggest minimal excretion; monitor for bradycardia & hypotension

No Known Risk

None

General	Excretion Potential	Effect on Infant	Notes
			None

Contraindicated

None

Precaution Exists

Hydrochlorothiazide

Cardiovascular-Increased sensitivity to effects on blood pressure. Metabolic-More likely to develop hypokalemia, hypomagnesemia, or hyponatremia. Endocrine-May exacerbate SIADH. May worsen glucose control in patients with diabetes. Renal-Not effective with CrCL < 30mL/min.

Cardiovascular-Minimize dose to decrease dizziness and falls. Worsening cardiac failure may occur during up-titration of beta-blockers.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	Y	N	Y	N	N	Y

BEERS: Y     HEDIS: N     STOPP: Y

Metoprolol

Cardiovascular-Increased sensitivity to effects on blood pressure. Metabolic-More likely to develop hypokalemia, hypomagnesemia, or hyponatremia. Endocrine-May exacerbate SIADH. May worsen glucose control in patients with diabetes. Renal-Not effective with CrCL < 30mL/min.

Cardiovascular-Minimize dose to decrease dizziness and falls. Worsening cardiac failure may occur during up-titration of beta-blockers.

Organ / System	HEP	REN	CARD	ENDO	NEURO / PSYCH	PULM
Increased Risk / Adverse Effects	N	N	N	N	N	N

BEERS: N     HEDIS: N     STOPP: Y

No Known Risk

None

0-9	A-Z
I10	Essential (primary) hypertension
I11	Hypertensive heart disease
I11.0	Hypertensive heart disease with heart failure
I11.9	Hypertensive heart disease without heart failure
I12	Hypertensive chronic kidney disease
I12.0	Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease
I12.9	Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13	Hypertensive heart and chronic kidney disease
I13.0	Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13.1	Hypertensive heart and chronic kidney disease without heart failure
I13.10	Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13.11	Hypertensive heart and chronic kidney disease without heart failure, with stage 5 chronic kidney disease, or end stage renal disease
I13.2	Hypertensive heart and chronic kidney disease with heart failure and with stage 5 chronic kidney disease, or end stage renal disease
I15.1	Hypertension secondary to other renal disorders